Plasma membrane Ca2+-ATPase extrudes Ca2+ from hair cell stereocilia

Journal of Neuroscience

Volumn 18, Issue 2, 1998, Pages 610-624

  Yamoah, Ebenezer N ^a,c,e   Lumpkin, Ellen A ^d   Dumont, Rachel A ^a   Smith, Peter J S ^c   Hudspeth, A J ^d   Gillespie, Peter G ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MARINE BIOLOGICAL LABORATORY   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e UNIVERSITY OF CINCINNATI   (United States)

Author keywords

ATPase; Calcium; Hair bundle; Hair cell; Hearing; Ion selective probe; Stereocilia

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM ION; CALMODULIN BINDING PROTEIN; APAMIN; CALCIUM; STRONTIUM; VANADIC ACID;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CELL MEMBRANE; DIALYSIS; ENDOLYMPH; ENZYME ANALYSIS; ENZYME LOCALIZATION; EXTRACELLULAR CALCIUM; FROG; HAIR CELL; HEARING; IMMUNOBLOTTING; ION SELECTIVE ELECTRODE; MEMBRANE CURRENT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEREOCILIUM; ANIMAL; BIOLOGICAL MODEL; CHEMOLUMINESCENCE; CYTOLOGY; ENZYME IMMUNOASSAY; ENZYMOLOGY; METABOLISM; VESTIBULE;

ANIMALS; APAMIN; CALCIUM; CALCIUM-TRANSPORTING ATPASES; CELL MEMBRANE; CHEMILUMINESCENT MEASUREMENTS; HAIR CELLS, VESTIBULAR; IMMUNOENZYME TECHNIQUES; MODELS, BIOLOGICAL; RANA CATESBEIANA; SACCULE AND UTRICLE; STRONTIUM; VANADATES;

EID: 0031594190     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-02-00610.1998     Document Type: Article

References (19)

1. 2+ pump. J Biol Chem 267:14244-14249.
2. Ammann D (1986) Ion-selective microelectrodes: principles, design and application. New York: Springer.
3. Assad JA, Corey DP (1992) An active motor model for adaptation by vertebrate hair cells. J Neurosci 12:3291-3309.
4. Assad JA, Shepherd GMG, Corey DP (1991) Tip-link integrity and mechanical transduction in vertebrate haircells. Neuron 7:985-994.
5. Denser ME, Issa NP, Hudspeth AJ (1993) Hair bundle stiffness dominates the elastic reactance to otolithic membrane shear. Hear Res 68:243-252.
6. Benser ME, Marquis RE, Hudspeth AJ (1996) Rapid, active hair bundle movements in hair cells from the bullfrog's sacculus. J Neurosci 16:5629-5643.
7. Berg HC (1993) Random walks in biology, Expanded Ed. Princeton, NJ: Princeton UP.
8. Bosher SK, Warren RL (1978) Very low calcium content of cochlear endolymph, an extracellular fluid. Nature 273:377-378.
9. Bronner F (1989) Renal calcium transport: mechanisms and regulation-an overview. Am J Physiol 26:F707-F711.
10. Burnham JA, Sterling CE (1984) Quantitative localization of Na-K pump sites in the frog sacculus. J Neurocytol 13:617-638.
11. Carafoli E (1991) Calcium pump of the plasma membrane. Physiol Rev 71:129-153.
12. Carslaw HS, Jaeger JC (1959) Conduction of heat in solids, 2nd Ed. Oxford: Oxford UP.
13. Corcy DP, Hudspeth AJ (1979) Ionic basis of the receptor potential in a vertebrate hair cell. Nature 281:675-677.
14. Corey DP, Hudspeth AJ (1980) Mechanical stimulation and micromanipulation with piezoelectric bimorph elements. J Neurosci Methods 3:183-202.
15. Corey DP, Hudspeth AJ (1983) Kinetics of the receptor current in bullfrog saccular hair cells. J Neurosci 3:962-976.
16. Crawford AC, Evans MG, Fettiplace R (1991) The actions of calcium on the mechanoelectrical transducer current of the turtle hair cells. J Physiol (Lond) 434:369-398.
17. Crouch JJ, Schulte BA (1995) Expression of plasma membrane CaATPase in the adult and developing gerbil cochlea. Hear Res 92:112-119.
18. Crouch JJ, Schulte BA (1996) Identification and cloning of site C splice variants of plasma membrane Ca-ATPase in the gerbil cochlea. Hear Res 101:55-61.
19. Denk W, Holt JR, Shepherd GMG, Corey DP (1995) Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links. Neuron 15:1311-1321.