The activation and inhibition of human nicotinic acetylcholine receptor by RJR-2403 indicate a selectivity for the α4β2 receptor subtype

Journal of Neurochemistry

Volumn 75, Issue 1, 2000, Pages 204-216

  Papke, Roger L ^a   Webster, J Christopher ^a   Lippiello, Patrick M ^b   Bencherif, Merouane ^b   Francis, Michael M ^a,c  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b Targacept   (United States)

^c Department of Obstetrics Gynecology   (United States)

Author keywords

Alzheimer's disease; Desensitization; Noncompetitive inhibition; Voltage clamp

Indexed keywords

ACETYLCHOLINE; N METHYL 4 (3 PYRIDINYL) 3 BUTENAMINE; NICOTINE; NICOTINIC RECEPTOR; RECEPTOR SUBTYPE;

ARTICLE; COMPETITIVE INHIBITION; DESENSITIZATION; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; VOLTAGE CLAMP; XENOPUS;

ACETYLCHOLINE; ANIMALS; ELECTRIC CONDUCTIVITY; FEMALE; HUMANS; NICOTINE; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 0034126584     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0750204.x     Document Type: Article

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