Flt3 ligand structure and unexpected commonalities of helical bundles and cystine knots

Nature Structural Biology

Volumn 7, Issue 6, 2000, Pages 486-491

  Savvides, Savvas N ^a,c   Boone, Tom ^d   Karplus, P Andrew ^a,b  

^a Department of Population Medicine and Diagnostic Sciences   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLT3 LIGAND; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; STEM CELL FACTOR; VASCULOTROPIN;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; HUMAN; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING;

AMINO ACID SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYSTINE; DIMERIZATION; FMS-LIKE TYROSINE KINASE 3; HUMANS; LIGANDS; MACROPHAGE COLONY-STIMULATING FACTOR; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SEQUENCE ALIGNMENT; STEM CELL FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034124850     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/75896     Document Type: Article

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