메뉴 건너뛰기




Volumn 53, Issue 5, 2000, Pages 459-466

F-12509A, a new sphingosine kinase inhibitor, produced by a discomycete

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; F 12509A; HYDROQUINONE DERIVATIVE; SESQUITERPENE; SPHINGOSINE KINASE; UNCLASSIFIED DRUG;

EID: 0034121965     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.459     Document Type: Article
Times cited : (48)

References (26)
  • 1
    • 0014833032 scopus 로고
    • Metabolism of sphingosine bases. XV. Enzymatic degradation of 4t-sphingenine 1-phosphate (sphingosine 1-phosphate) to 2t-hexadecen-1-al and ethanolamine phosphate
    • STOFFEL, W. & G. ASSMANN: Metabolism of sphingosine bases. XV. Enzymatic degradation of 4t-sphingenine 1-phosphate (sphingosine 1-phosphate) to 2t-hexadecen-1-al and ethanolamine phosphate. Hoppe Seyler's Z. Physiol. Chem. 51: 1041-1049, 1970
    • (1970) Hoppe Seyler's Z. Physiol. Chem. , vol.51 , pp. 1041-1049
    • Stoffel, W.1    Assmann, G.2
  • 2
    • 0029862561 scopus 로고    scopus 로고
    • Sphingolipid metabolism and cell growth regulation
    • SPIEGEL, S. & A. H. MERRILL, Jr.: Sphingolipid metabolism and cell growth regulation. FASEB J. 10: 1388-1397, 1996
    • (1996) FASEB J. , vol.10 , pp. 1388-1397
    • Spiegel, S.1    Merrill A.H., Jr.2
  • 3
    • 0029027837 scopus 로고
    • Sphingolipid metabolites: Members of a new class of lipid second messengers
    • SPIEGEL, S. & S. MILSTIEN: Sphingolipid metabolites: members of a new class of lipid second messengers. J. Membr. Biol. 146: 225-237, 1995
    • (1995) J. Membr. Biol. , vol.146 , pp. 225-237
    • Spiegel, S.1    Milstien, S.2
  • 4
    • 0029996127 scopus 로고    scopus 로고
    • Calcium mobilization via sphingosine kinase in signaling by the Fc ε RI antigen receptor
    • CHOI, O. H.; J. H. KIM & J. P. KINET: Calcium mobilization via sphingosine kinase in signaling by the Fc ε RI antigen receptor. Nature 380: 634-636, 1996
    • (1996) Nature , vol.380 , pp. 634-636
    • Choi, O.H.1    Kim, J.H.2    Kinet, J.P.3
  • 5
    • 0030780015 scopus 로고    scopus 로고
    • Involvement of sphingosine-1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
    • EDSALL, L. C.; G. G. PIRIANOV & S. SPIEGEL: Involvement of sphingosine-1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. J. Neurosci. 17: 6952-6960, 1997
    • (1997) J. Neurosci. , vol.17 , pp. 6952-6960
    • Edsall, L.C.1    Pirianov, G.G.2    Spiegel, S.3
  • 6
    • 0029027589 scopus 로고
    • Sphingosine 1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: Spatial and temporal modulation of PDGF chemotactic signal transduction
    • BORNFELDT, K. E.; L. M. GRAVES, E. W. RAINES, Y. IGARASHI, G. WAYMAN, S. YAMAMURA, Y. YATOMI, J. S. SIDHU, E. G. KREBS, S. HAKOMORI & R. ROSS: Sphingosine 1-phosphate inhibits PDGF-induced chemotaxis of human arterial smooth muscle cells: spatial and temporal modulation of PDGF chemotactic signal transduction. J. Cell Biol. 130: 193-206, 1995
    • (1995) J. Cell Biol. , vol.130 , pp. 193-206
    • Bornfeldt, K.E.1    Graves, L.M.2    Raines, E.W.3    Igarashi, Y.4    Wayman, G.5    Yamamura, S.6    Yatomi, Y.7    Sidhu, J.S.8    Krebs, E.G.9    Hakomori, S.10    Ross, R.11
  • 7
    • 0030868653 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action and in a pertussis toxin-insensitive manner
    • YAMAMURA, S.; Y. YATOMI, F. RUAN, E. A. SWEENEY, S. HAKOMORI & Y. IGARASHI: Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action and in a pertussis toxin-insensitive manner. Biochemistry 36: 10751-10759, 1997
    • (1997) Biochemistry , vol.36 , pp. 10751-10759
    • Yamamura, S.1    Yatomi, Y.2    Ruan, F.3    Sweeney, E.A.4    Hakomori, S.5    Igarashi, Y.6
  • 8
    • 0029052921 scopus 로고
    • Sphingosine 1-phosphate: A platelet-activating sphingolipid released from agonist-stimulated human platelets
    • YATOMI, Y.; F. RUAN, S. HAKOMORI & Y. IGARASHI: Sphingosine 1-phosphate: a platelet-activating sphingolipid released from agonist-stimulated human platelets. Blood 86: 193-202, 1995
    • (1995) Blood , vol.86 , pp. 193-202
    • Yatomi, Y.1    Ruan, F.2    Hakomori, S.3    Igarashi, Y.4
  • 10
    • 0029879915 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate rapidly induces Rho-dependent neurite retraction: Action through a specific cell surface receptor
    • POSTMA, F. R.; K. JALINK, T. HENGEVELD & W. H. MOOLENAAR: Sphingosine 1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor. EMBO J. 15: 2388-2392, 1996
    • (1996) EMBO J. , vol.15 , pp. 2388-2392
    • Postma, F.R.1    Jalink, K.2    Hengeveld, T.3    Moolenaar, W.H.4
  • 11
    • 0027371722 scopus 로고
    • Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens
    • OLIVERA, A. & S. SPIEGEL: Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365: 557-560, 1993
    • (1993) Nature , vol.365 , pp. 557-560
    • Olivera, A.1    Spiegel, S.2
  • 12
    • 0026049696 scopus 로고
    • Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
    • ZHANG, H.; N. N. DESAI, A. OLIVERA, T. SEKI, G. BROOKER & S. SPIEGEL: Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 114: 155-167, 1991
    • (1991) J. Cell Biol. , vol.114 , pp. 155-167
    • Zhang, H.1    Desai, N.N.2    Olivera, A.3    Seki, T.4    Brooker, G.5    Spiegel, S.6
  • 13
    • 0030054341 scopus 로고    scopus 로고
    • N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets
    • YATOMI, Y.; F. RUAN, T. MEGIDISH, T. TOYOKUNI, S. HAKOMORI & Y. IGARASHI: N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets. Biochemistry 35: 626-633, 1996
    • (1996) Biochemistry , vol.35 , pp. 626-633
    • Yatomi, Y.1    Ruan, F.2    Megidish, T.3    Toyokuni, T.4    Hakomori, S.5    Igarashi, Y.6
  • 14
    • 0024439904 scopus 로고
    • Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities
    • IGARASHI, Y.; S. HAKOMORI, T. TOYOKUNI, B. DEAN, S. FUJITA, M. SUGIMOTO, T. OGAWA, K. E. GHENDY & E. RACKER: Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities. Biochemistry 28: 6796-6800, 1989
    • (1989) Biochemistry , vol.28 , pp. 6796-6800
    • Igarashi, Y.1    Hakomori, S.2    Toyokuni, T.3    Dean, B.4    Fujita, S.5    Sugimoto, M.6    Ogawa, T.7    Ghendy, K.E.8    Racker, E.9
  • 15
    • 0025045879 scopus 로고
    • Protein kinase C and platelet inhibition by D-erythro-sphingosine: Comparison with N,N-dimethylsphingosine and commercial preparation
    • KHAN W. A.; R. DOBROWSKY, S. TOUNY & Y. A. HANNUN: Protein kinase C and platelet inhibition by D-erythro-sphingosine: comparison with N,N-dimethylsphingosine and commercial preparation. Biochem. Biophys. Res. Commun. 172: 683-691, 1990
    • (1990) Biochem. Biophys. Res. Commun. , vol.172 , pp. 683-691
    • Khan, W.A.1    Dobrowsky, R.2    Touny, S.3    Hannun, Y.A.4
  • 16
    • 0030004270 scopus 로고    scopus 로고
    • Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines
    • SWEENEY, E. A.; C. SAKAKURA, T. SHIRAHAMA, A. MASAMUNE, H. OHTA, S. HAKOMORI & Y. IGARASHI: Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines. Int. J. Cancer 66: 358-366, 1996
    • (1996) Int. J. Cancer , vol.66 , pp. 358-366
    • Sweeney, E.A.1    Sakakura, C.2    Shirahama, T.3    Masamune, A.4    Ohta, H.5    Hakomori, S.6    Igarashi, Y.7
  • 18
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • BLIGH, E. G. & W. J. DYER: A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-918, 1959
    • (1959) Can. J. Biochem. Physiol. , vol.37 , pp. 911-918
    • Bligh, E.G.1    Dyer, W.J.2
  • 19
    • 0032817681 scopus 로고    scopus 로고
    • Scyphostatin, a neutral sphingomyelinase inhibitor from a discomycete, Trichopeziza mollissiama: Taxonomy of the producing organism, fermentation, isolation and physico-chemical properties
    • NARA, F.; M. TANAKA, T. HOSOYA, K. S. KONAGAI & T. OGITA: Scyphostatin, a neutral sphingomyelinase inhibitor from a discomycete, Trichopeziza mollissiama: Taxonomy of the producing organism, fermentation, isolation and physico-chemical properties. J. Antibiotics 52: 525-530, 1999
    • (1999) J. Antibiotics , vol.52 , pp. 525-530
    • Nara, F.1    Tanaka, M.2    Hosoya, T.3    Konagai, K.S.4    Ogita, T.5
  • 20
    • 0027992342 scopus 로고
    • Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells
    • GOLD, M. R.; V. DURONIO, S. P. SAXENA, J. W. SCHRADER & R. AEBERSOLD: Multiple cytokines activate phosphatidylinositol 3-kinase in hemopoietic cells. J. Biol. Chem. 269: 5403-5412, 1994
    • (1994) J. Biol. Chem. , vol.269 , pp. 5403-5412
    • Gold, M.R.1    Duronio, V.2    Saxena, S.P.3    Schrader, J.W.4    Aebersold, R.5
  • 21
    • 0342361301 scopus 로고
    • Notes on the genus Trichopezizella with descriptions of new taxa
    • HAINES, J. H.: Notes on the genus Trichopezizella with descriptions of new taxa. Mycologia 66: 213-241, 1974
    • (1974) Mycologia , vol.66 , pp. 213-241
    • Haines, J.H.1
  • 22
    • 0343666474 scopus 로고    scopus 로고
    • Application of underutilized microbial resouces in drug discovery: A review focused on discomycetes
    • HOSOYA, T.: Application of underutilized microbial resouces in drug discovery: a review focused on discomycetes. Annual Report of Sankyo Research Laboratories 50: 15-40, 1998
    • (1998) Annual Report of Sankyo Research Laboratories , vol.50 , pp. 15-40
    • Hosoya, T.1
  • 23
    • 0026488221 scopus 로고
    • Structures of stealthins A and B, new free radical scavengers of microbial origin
    • SHIN-YA, K.; K. FURIHATA, Y. TESHIMA, Y. HAYAKAWA & H. SETO: Structures of stealthins A and B, new free radical scavengers of microbial origin. Tetrahedron Lett. 33: 7025-7028, 1992
    • (1992) Tetrahedron Lett. , vol.33 , pp. 7025-7028
    • Shin-Ya, K.1    Furihata, K.2    Teshima, Y.3    Hayakawa, Y.4    Seto, H.5
  • 24
    • 0015694524 scopus 로고
    • Zonarol and isozonarol, fungitoxic hydroquinones from the brown seaweed Dictyopteris zonarioides
    • FENICAL, W.; J. J. SIMS, D. SQUATRITO, R. M. WING & P. RANDLICK: Zonarol and isozonarol, fungitoxic hydroquinones from the brown seaweed Dictyopteris zonarioides. J. Org. Chem. 38: 2383-2386, 1973
    • (1973) J. Org. Chem. , vol.38 , pp. 2383-2386
    • Fenical, W.1    Sims, J.J.2    Squatrito, D.3    Wing, R.M.4    Randlick, P.5
  • 25
    • 0028348152 scopus 로고
    • Three new sesquiterpene hydroquinones from marine origin
    • TALPIR, R.; A. RUDI, Y. KASHMAN, Y. LOYA & A. HIZI: Three new sesquiterpene hydroquinones from marine origin. Tetrahedron 50: 4179-4184, 1994
    • (1994) Tetrahedron , vol.50 , pp. 4179-4184
    • Talpir, R.1    Rudi, A.2    Kashman, Y.3    Loya, Y.4    Hizi, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.