Reflections on the role of the thiol group in biology

Annals of the New York Academy of Sciences

Volumn 899, Issue , 2000, Pages 148-158

  Haugaard, Niels ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; OXYGEN; THIOL GROUP;

BIOLOGY; CELL FUNCTION; CELL METABOLISM; CONFERENCE PAPER; DIABETES MELLITUS; ENERGY METABOLISM; GLYCOLYSIS; MITOCHONDRION; OXIDATION; OXYGEN TOXICITY;

EID: 0034121840     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb06183.x     Document Type: Conference Paper

References (58)

1. 1. BARRON, E.S.G. 1951. Thiol groups of biological importance. Adv. Enzymol. 11: 201-266.
2. 2. SINGER, T.P. 1948. On the mechanism of enzyme inhibition by sulfhydryl reagents. J. Biol. Chem. 174: 11-21.
3. 3. HAUGAARD, N. 1946. Oxygen poisoning XI. The relation between inactivation of enzymes by oxygen and essential sulfhydryl groups. J. Biol. Chem. 164: 265-270.
4. 4. HAUGAARD, N. 1968. Cellular mechanisms of oxygen toxicity. Physiol. Rev. 48: 311-373.
5. 5. HENRIKSEN, E.J., S. JACOB, R.S. STREEPER, D.L. FOGT, J.Y. HOKAMA & H.J. TRITSCHLER. 1997. Stimulation by α-lipoic acid of glucose transport activity in skeletal muscle of lean and obese Zucker rats. Life Sci. 61: 805-812
6. 6. MEISTER, A. 1988. On the discovery of glutathione. Trends Biochem. Sci. 13: 185-188.
7. 7. COLOWICK, S. et al., Eds. 1954. Glutathione. A Symposium. Academic Press. New York.
8. 8. ARIAS, I.M. & W.B. JACOBY, Eds. 1976. Glutathione Metabolism and Function. Raven Press. New York.
9. 9. HELLERMAN, L. 1937. Reversible inactivation of certain hydrolytic enzymes. Physiol. Rev. 17: 454-484.
10. 10. DUNN, J.S., H.L. SHEEHAN & N.G.B. MCLETCHIE. 1943. Necrosis of islets of Langerhans produced experimentally. Lancet I: 384-387.
11. 11. LAHIRI, S. 1981. Chemical modification of carotid body chemoreception by sulfhydryls. Science 212: 1065-1066.
12. 12. ELLMAN, G.L. 1959. Tissue sulfhydryl groups Arch. Biochem. Biophys. 82: 70-77.
13. 13. ROBINSON, K.B., JR. R.G. BRENT, P. SUMEGI & P.A. SRERE. 1989. An enzymatic approach to the study of the Krebs tricarboxylic acid cycle. In Mitochondria: A Practical Approach. V.M. Darley Usmar, D. Rickwood & M.T. Wilson, Eds. :153-170. IRS Press. Oxford.
14. 14. DIXON, M. & E.C. WEBB. 1964. Enzymes. Academic Press. New York, p. 344.
15. 15. CLELAND, W.W. 1964. Dithiothreitol, a new protective reagent for SH groups. Biochemistry 3: 480-482.
16. 16. LUNDSGAARD, E. 1932. Weitere Untersuchungen uber die Einwirkung der Halogenessigsauren auf der Spaltung-und Oxidationsstoffwechsel. Biochem. Ztschr. 250: 61-88.
17. 17. CAIN, D.F. & R.E. DAVIES. 1962. Breakdown of adenosinetriphosphate during a single contraction of working muscle. Biochem. Biophys. Res. Commun. 8: 361-366.
18. 18. FONYO, A. & S.P. BESSMAN. 1966. The action of oligomycin and parahydroxymercuribenzoate on mitochondrial respiration stimulated by ADP, arsenate and calcium. Biochem. Biophys Res. Commun. 24: 61-66.
19. 19. HAUGAARD, N., N.H. LEE, R. KOSTRZEWA, R.S. HORN & E.S. HAUGAARD. 1969. The role of sulfhydryl groups in oxidative phosphorylation and ion transport by rat liver mitochondria. Biochim. Biophys. Acta 172: 198-204.
20. 20. HAUGAARD, N., N.H. LEE, P. CHUDAPONGSE, C.D. WILLIAMS & E.S. HAUGAARD. 1970. The actions of disulfiram and 2,2-dithiopyridine on oxidative phosphorylation and ion transport by rat liver mitochondria. Biochem. Pharmacol. 19: 2969-2971.
21. 21. FONYO, A. 1974. Phosphate carrier of liver mitochondria: two equivalent SH-groups in the carrier unit. Biochem Biophys. Res. Commun. 57: 1069-1073.
22. 22. FONYO, A. 1978. SH-group reagents as tools in the study of mitochondrial anion transport. A review. J. Bioenerg. Biomembr. 10: 171-194
23. 23. WEHRLE, J.P & P.L. PEDERSEN. 1981. Phosphate transport in rat liver mitochondria: location of sulfhydryl groups essential for transport activities. J. Bioenerg. Biomembr. 13: 285-294.
24. 24. WOHLRAB, H. & N. FLOWERS. 1982. pH-gradient-dependent phosphate transport catalyzed by the purified mitochondrial phosphate transport protein. J. Biol. Chem. 257: 28-31.
25. 25. LAVIS, R. & R.H. WILLIAMS. 1970. Studies of the insulin-like actions of thiols upon isolated fat cells. J. Biol. Chem. 245: 23-31.
26. 26. SINGH, H.P.P. & R.H. BOWMAN. 1970. Effect of DL-α-lipoic acid on the citrate concentration and fructophosphokinase activity by perfused hearts from normal and diabetic rats. Biochem. Biophys. Res. Commun. 41: 555-561.
27. 27. HAUGAARD, N. & E.S. HAUGAARD. 1970. Stimulation of glucose utilization by thioctic acid in rat diaphragm incubated in vitro. Biochim. Biophys. Acta 222: 583-586.
28. 28. HAUGAARD, E.S., M.J. SMITH & N. HAUGAARD. 1972. Effects of thiols and disulfides on glucose utilization and insulin action in the isolated rat diaphragm. Biochem. Pharmacol. 21: 517-523.
29. 29. HENRIKSEN, E J. & J.O. HOLOSZY. 1990. Effects of phenylarsine oxide on stimulation of glucose transport in rat skeletal muscle. Am. J. Physiol. 258: C648-C653.
30. 30. HENRIKSEN, E.J & S. JACOB. 1994. Chronic thioctic acid treatment increases insulin stimulated glucose transport activity in skeletal muscle of obese Zucker rats. Diabetes 43 (Suppl. 1): 122A.
31. 31. JACOB, S., R.S. STREEPER, D. FOGT, J.Y. HOKAMA, H.J. TRITCHLER, G.J. DIETZE & E.J. HENRIKSEN. 1996. The antioxidant α-lipoic acid enhances insulin-stimulated glucose metabolism in insulin-resistant rat skeletal muscle. Diabetes 45: 1024-1029.
32. 32. STREEPER, R.S., E.J. HENRIKSEN, S. JACOB, J.Y. HOKAMA, D.L. FOGT & H.J. TRITCHLER. 1997. Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle. Am. J. Physiol. 273: E185-E191.
33. 33. KLIP, A., A. VOLCHUK, T. RANLAL, C. ACKERLEY & Y. MITSUMOTO. 1994. In Molecular Biology of Diabetes, Vol. II. B. Draznin & D. Leroith, Eds. :511-528. Humana Press. Totowa, NJ.
34. 34. HAUGAARD, E.S. & N. HAUGAARD. 1974. The action of insulin on glycogen synthesis in rat diaphragm from intracellular and extracellular glucose. Biochim. Biophys. Acta 338: 309-316.
35. 35. HAUGAARD, E.S., R.A. MICKEL & N. HAUGAARD. 1973. Actions of lithium ions and insulin on glucose utilization glycogen synthesis and glycogen synthase in the isolated rat diaphragm. Biochem. Pharmacol. 23: 1675-1685.
36. 36. FÜRNSINN, C., C. NOE, R. HERDLICKA, M. RODEN, P. NOWOTNY, B. LEIGHTON & W. WALDHXUSL. 1997. More marked stimulation by lithiuim than insulin of the glycogenis pathway in skeletal muscle. Am. J. Physiol. 273: E514-E520.
37. 37. DAVIDHEISER, S., E.S. HAUGAARD & N. HAUGAARD. 1979. Effects of epinephrine and the cyclic AMP phosphodiesterase inhibitor SQ 20009 on glucose and glycogen metabolism in skeletal muscle. Biochem. Pharmacol. 28: 807-813.
38. 38. HAUGAARD, N., R.M. LEVIN & A.J. WEIN. 1987. In vitro studies of glucose metabolism of the rabbit urinary bladder. J. Urol. 137: 782-784.
39. 39. BUSTAMANTE, J., J.K. LODGE, L. MARCONI, H.J. TRITCHLER, L. PACKER & B.H. RIHN. 1998. α-Lipoic acid in liver metabolism and disease. Free Rad. Biol. Med. 24: 1023-1039.
40. 40. BUSSE, E., G. ZIMMER, B. SCHOPOHL & B. KORNHUBER. 1992. Influence of alpha lipoic acid on intracellular glutathione in vitro and in vivo. Artzneimittelforschung 42: 829-831.
41. 41. PACKER, L., H.J. TRITCHLER & K. WESSEL. 1997. Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free Rad. Biol. Med. 22: 359-378.
42. 42. SACHSE, G. & B. WILLMS. 1980. Efficacy of thioctic acid in the therapy of peripheral diabetic neuropathy. In Aspects of Autonomic Neuropathy in Diabetes. F.A. Gries, H.J. Freund, F. Rabe & H. Berger, Eds. :105-108. Thieme.
43. 43. ZIEGLER, D., M. HANEFELD, K.J. RUHNAU, H.P. MEISNER, et al. 1996. Treatment of symptomatic diabetic peripheral neuropathy with the antioxidant α-lipoic acid. Diabetologia 38: 1425-1433.
44. 44. BERT, P. 1878. Barometric Pressure: Researches in Experimental Physiology. Translated by M.A. Hitchcock & F.A. Hitchcock. College Book Co. Columbus OH.
45. 45. STADIE, W.C., B.C. RIGGS & N. HAUGAARD. 1944. Oxygen poisoning. Am. J. Med. Sci. 207: 84-114.
46. 46. DICKENS, F. & E. NEIL, Eds. 1964. Oxygen in the Animal Organism. Pergamon Press. Oxford.
47. 47. HAYAISHI, O. 1974. Molecular Oxygen in Biology. American Elsevier. New York.
48. 48. GILBERT, D.L., Ed. 1981. Oxygen and Living Processes. An Interdisciplinary Approach. Springer Verlag. New York.
49. 49. JAMIESON, D. 1989. Oxygen toxicity and reactive oxygen metabolites in mammals. Free Rad. Biol. Med. 7: 87-108.
50. 50. GERSCHMAN, R., D.L. GILBERT, S.W. NYE, P. DWYER & W.O. FENN. 1954. Oxygen poisoning and X-radiation: a mechanism in common. Science 119: 623-625.
51. 51. GILBERT, D.L. 1996. Rebeca Gerschman: a personal remembrance. Free Rad. Biol. Med. 21: 1-4.
52. 52. BOVERIS, A.A. 1996. Rebeca Gerschman: a brilliant woman scientist in the fifties. Free Rad. Biol. Med. 21: 5-6.
53. 53. MCCORD, J.M. & I. FRIDOVICH. 1969. Superoxide dismutase: an enzymatic function for erythrocuprein (Hemocrupein). J. Biol. Chem. 244: 6049-6055.
54. 54. DIGUISEPPI, J. & I. FRIDOVICH. 1984. The toxicology of molecular oxygen. Crit. Rev. Toxicol. 12: 315-342.
55. 55. TJIOE, G. & N. HAUGAARD. 1972. Oxygen inhibition of crystalline glyceraldehyde phosphate dehydrogenase and disappearance of enzyme sulfhydryl groups. Life Sci. 11: 329-335.
56. 56. JAMIESON, D. & H.A.S. VAN DEN BRINK. 1962. Pulmonary damage due to high pressure oxygen breathing in rat. 2. Changes in dehydrogenase activity of rat lung. Aust. J. Exp. Biol. Med.Sci. 20: 51-56.
57. 57. JAMIESON, D., K. LADNER & H.A.S. VAN DEN BRINK. 1963. Pulmonary damage due to high pressure oxygen breathing in rat. 4. Quantitative analysis of sulfhydryl and disulphide groups in rat lung. Aust. J. Exp. Biol. Med. Sci. 41: 491-498.
58. 58. PIRIE, N.W. 1983. Sir Frederick Gowland Hopkins (1861-1947). In Comprehensive Biochemistry, Vol 35. Selected Topics in the History of Biochemistry. Personal Recollections 1. Elsevier Science Publishers. Amsterdam, pp. 103-127.