Comparative genomic hybridization reveals complex genetic changes in primary breast cancer tumors and their cell lines

Cancer Genetics and Cytogenetics

Volumn 119, Issue 2, 2000, Pages 132-138

  Larramendy, Marcelo L ^a,b   Lushnikova, Tamara ^a   Björkqvist, Anna Maria ^a   Wistuba, Ignacio I ^c   Virmani, Arvind K ^c   Shivapurkar, Narayan ^c   Gazdar, Adi F ^c   Knuutila, Sakari ^d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b FACULTAD DE CIENCIAS NATURALES Y MUSEO   (Argentina)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; CANCER; CANCER CELL CULTURE; CARCINOGENESIS; CHROMOSOME 13Q; CHROMOSOME 17Q; CHROMOSOME 1Q; CHROMOSOME 8Q; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENE ISOLATION; GENE MAPPING; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL;

BREAST NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENE AMPLIFICATION; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; NUCLEIC ACID HYBRIDIZATION; TUMOR CELLS, CULTURED;

EID: 0034120979     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(99)00226-5     Document Type: Article

References (35)

1. Holford T.R., Roush G.C., McKay L.A. Trends in female breast cancer in Connecticut and the United States. J Clin Epidemiol. 44:1991;29-39.
2. Harris J.R., Lippman M.E., Veronesi U., Willet W. Breast cancer. N Engl J Med. 327:1992;473-480.
3. Slovak M.L. Breast tumor cytogenetic markers. Wolman S.R., Sell S. Human Cytogenetic Markers. 1996;111-149 Humana Press Inc, Totowa, NJ.
4. Mitelman F. Catalog of Chromosome Aberrations in Cancer. 1994;Wiley-Liss, New York.
5. Heim S., Mitelman F. Cancer Cytogenetics. 1995;Wiley-Liss, New York.
6. Kuukasjärvi T., Tanner M., Pennanen S., Karhu R., Visakorpi T., Isola J. Optimizing DOP-PCR for universal amplification of small DNA samples in comparative genomic hybridization. Genes Chromosom Cancer. 18:1997;94-101.
7. Knuutila S., Autio K., Björkqvist A.-M., El-Rifai W., Hemmer S., Huhta T., Kettunen E., Kiuru-Kuhlefelt S., Larramendy M.L., Lushnikova T., Monni O., Pere H., Tapper J., Tarkkanen M., Varis A., Wasenius V.-M., Wolf M., Zhu Y. DNA copy number losses in human neoplasms. Am J Pathol. 155:1999;683-694.
8. Kallioniemi A., Kallioniemi O.-P., Sudar D., Rutovitz D., Gray J.W., Waldman F., Pinkel D. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science. 258:1992;818-821.
9. Knuutila S., Björkqvist A.-M., Autio K., Tarkkanen M., Wolf M., Monni O., Szymanska J., Larramendy M.L., Tapper J., Pere H., El-Rifai W., Hemmer S., Wasenius V.-M., Vidgren V., Zhu Y. DNA copy number amplifications in human neoplasms. Review of comparative genomic hybridization studies. Am J Pathol. 152:1998;1107-1123.
10. Kuukasjärvi T., Karhu R., Tanner M., Kähkönen M., Schäffer A., Nupponen N., Pennanen S., Kallioniemi A., Kallioniemi O.-P., Isola J. Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer. Cancer Res. 57:1997;1597-1604.
11. Courjal F., Theillet C. Comparative genomic hybridization analysis of breast tumors with predeterminated profiles of DNA amplification. Cancer Res. 57:1997;4368-4377.
12. Ried T., Just K.E., Holtgreve-Grez H., du Manoir S., Speicher M.R., Schröck E., Latham C., Blegen H., Zetterberg A., Cremer T., Auer G. Comparative genomic hybridization of formalin-fixed, paraffin-embedded breast tumors reveals different patterns of chromosomal gains and losses in fibroadenomas and diploid and aneuploid carcinomas. Cancer Res. 55:1995;5415-5423.
13. James L.A., Mitchell E.L., Menansce L., Varley J.M. Comparative genomic hybridization of ductal carcinoma in situ of the breast. identification of regions of DNA amplification and deletion in common with invasive breast carcinoma Oncogene. 14:1997;1059-1065.
14. Kuukasjärvi T., Tanner M., Pennanen S., Karhu R., Kallioniemi O.-P., Isola J. Genetic changes in intraductal breast cancer detected by comparative genomic hybridization. Am J Pathol. 150:1997;1465-1471.
15. Kallioniemi A., Kallioniemi O.-P., Piper J., Tanner M., Stroke T., Chen L., Smith H.S., Pinkel D., Gray J.W., Waldman F.M. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc Natl Acad Sci USA. 91:1994;2156-2160.
16. Nishizaki T., DeVries S., Chew K., Goodson W.H., Ljung B.-M., Thor A., Waldman F.M. Genetic alteration in primary breast cancers and their metastases. direct comparison using modified comparative genomic hybridization Genes Chromosom Cancer. 19:1997;267-272.
17. Muleris M., Almeida A., Gerbault-Seureau M., Malfoy B., Dutrillaux B. Detection of DNA amplification in 17 primary breast carcinomas with homogeneous staining regions by a modified comparative genomic hybridization technique. Genes Chromosom Cancer. 10:1994;160-170.
18. Tirkkonen M., Tanner M., Karhu R., Kallioniemi A., Isola J., Kallioniemi O.-P. Molecular cytogenetics of primary breast cancer by CGH. Genes Chromosom Cancer. 21:1998;177-184.
19. Gazdar A.F., Kurvari V., Virmani A., Gollahon L., Sakaguchi M., Westerfield M., Kodagoda D., Stasny V., Cunningham H.T., Wistaba I.I., Tomlinson G., Tonk V., Ashfaq R., Leitch A.M., Minna J.D., Shay J.W. Characterization of pair-tumor and non-tumor cell lines established from patients with breast cancer. Int J Cancer. 78:1998;766-774.
20. Isola J., DeVries S., Chu L., Ghazvini S., Waldman F. Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples. Am J Pathol. 145:1994;1301-1308.
21. El-Rifai W., Larramendy M.L., Björkqvist A.-M., Hemmer S., Knuutila S. Optimization of comparative genomic hybridization using fluorochrome conjugated to dCTP and dUTP nucleotides. Lab Invest. 77:1997;699-700.
22. Larramendy M.L., El-Rifai W., Knuutila S. Comparison of fluorescein isothiocyanate- and Texas red-conjugated nucleotides for direct labeling in comparative genomic hybridization. Cytometry. 31:1998;174-179.
23. Isola J., Kallioniemi O.-P., Chu W., Fuqua S.A.W., Hilsenbeck S.G., Osborne C.K., Waldman F.M. Genetic aberrations detected by comparative genomic hybridization predict outcome in node-negative breast cancer. Am J Pathol. 147:1995;905-911.
24. Courjal F., Cuny M., Simony-Lafontaine J., Louason G., Speiser P., Zeillinger R., Rodriguez C., Theillet C. Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors. definition of phenotypic groups Cancer Res. 57:1997;4360-4367.
25. Persons D.L., Borelli K.A., Hsu P.H. Quantitation of HER-s/neu and c-myc gene amplification in breast carcinoma using fluorescence in situ hybridization. Mod Pathol. 10:1997;720-727.
26. Berns E.M., Klijn J.G., Smid M., van Staveren I.L., Look M.P., van Putten W.L., Foekens J.A. TP53 and MYC gene alterations independently predict poor prognosis in breast cancer patients. Genes Chromosom Cancer. 16:1996;170-179.
27. Misukami Y., Nonomura A., Takizawa T., Noguch M., Michigishi T., Nakamura S., Ishizaki T. N-myc protein expression in human breast cancer. prognostic implications Anticancer Res. 15:1995;2899-2905.
28. Tanner M., Tirkkonen M., Kallioniemi A., Isola J., Kuukasjärvi T., Collins C., Kowbel D., Guan X.Y., Trent J., Gray J.W., Meltzer P., Kallioniemi O.-P. Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer. Cancer Res. 56:1996;3441-3445.
29. Anzick S.L., Kononen J., Walker R.L., Aziosa D.O., Tanner M., Guan X.Y., Sauter G., Kallioniemi O.-P., Trent J.M., Meltzer P.S. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science. 277:1997;965-968.
30. Sen S., Zhou H., White R.A. A putative serine/threonine kinase encoding gene BTAK on chromosome 20q12 is amplified and overexpressed in human breast cancer cell lines. Oncogene. 14:1997;2195-2200.
31. Wiener J.R., Hurteau J.A., Kerns B.J., Whitaker R.S., Conaway M.R., Berchuck A., Bast R.J. Overexpression of the thyrosine phosphatase PTP1B is associated with human ovarian carcinomas. Am J Obstet Gynecol. 170:1994;1177-1183.
32. Hashimoto N., Goldstein B.J. Differential regulation of mRNAs encoding three protein-thyrosine phosphatases by insulin and activation of protein kinase C. Biochem Biophys Res Commun. 188:1992;1305-1311.
33. Tirkkonen M., Johannsson O., Agnarsson B.A., Olsson H., Ingvarsson S., Karhu R., Tanner M., Isola J., Barkardottir R.B., Borg A., Kallioniemi O.-P. Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations. Cancer Res. 57:1997;1222-1227.
34. Bieche I., Liderau R. A gene dosage effect is responsible for high overexpression of the MUC1 gene observed in human breast tumors. Cancer Genet Cytogenet. 98:1997;75-80.
35. II Wistuba, Behrens C., Milchgrub S., Syed S., Ahmadian M., Virmani A.K., Kurvari V., Cunningham T.H., Ashfaq R., Minna J.D., Gazdar A.F. Comparison of features of human breast cancer cell lines and their correponding tumors. Clin Cancer Res. 4:1998;2931-2938.