Overexpression of thyroid hormone receptor β1 is associated with thyrotropin receptor gene expression and proliferation in a human thyroid carcinoma cell line

Journal of Endocrinology

Volumn 165, Issue 2, 2000, Pages 379-389

  Chen, S T ^a   Shieh, H Y ^a   Lin, J D ^b   Chang, K S S ^a   Lin, K H ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

THYROID HORMONE RECEPTOR; THYROTROPIN RECEPTOR;

ARTICLE; CANCER GROWTH; CELL DIFFERENTIATION; CELL PROLIFERATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; THYROID CARCINOMA;

EID: 0034118687     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1650379     Document Type: Article

References (39)

1. Akiguchi I, Strauss K, Borges M, Silva JE & Moses JE 1992 Thyroid hormone receptors and 3,5,3′-triiodothyronine biological effects in FRTL-5 thyroid follicular cells. Endocrinology 131 1279-1287.
2. Barrera-Hernandez G, Zhan Q, Wong R & Cheng SY 1998 Thyroid hormone receptor is a negative regulator in p53-mediated signaling pathways. DNA and Cell Biology 17 743-750.
3. Berlingieri MT, Akamizu T, Fusco A, Grieco M, Colletta G, Cirafici AM, Ikuyama S, Kohn LD & Vecchio G, 1990 Thyrotropin receptor gene expression in oncogene-transfected rat thyroid cells: correlation between transformation, loss of thyrotropin-dependent growth, and loss of thyrotropin receptor gene expression. Biochemical and Biophysical Research Communications 173 172-178.
4. Bouterfa HL, Piedrafita FJ, Doenecke D & Pfahl M 1995 Regulation of H1 ° gene expression by nuclear receptors through an unusual response element: implications for regulation of cell proliferation. DNA and Cell Biology 14 909-919.
5. Brabant G, Maenhaut C, Korle J, Scheumann G, Dralle H, Hoang-Vu C, Hesch RD, von zur Muhlen A, Vassart G & Dumont JE 1991 Human thyrotropin receptor gene: expression in thyroid tumors and correlation to markers of thyroid differentiation and dedifferentiation. Molecular and Cellular Endocrinology 82 R7-R12.
6. Broecker M, Mayr GW & Derwahl M 1997 Suppression of thyrotropin receptor-G protein phospholipase C coupling by activation of protein kinase C in thyroid carcinoma cells. Endocrinology 138 3787-3796.
7. Bronnegard M, Torring O, Boos J, Sylven C, Marcus C & Wallin G 1994 Expression of thyrotropin receptor and thyroid hormone receptor messenger ribonucleic acid in normal, hyperplastic, and neoplastic human thyroid tissue. Journal of Clinical Endocrinology and Metabolism 79 384-389.
8. Cheng SY 1995 New insights into the structure and function of the thyroid hormone receptor. Jounal of Biomedical Science 2 77-89.
9. 3 receptor. Endocrinology 116 2062-2069.
10. Estour B, Van Herle AJ, Juillard GJF, Totanes TL, Sparkes RS, Giuliano AE & Klandorf H 1989 Characterization of a human follicular thyroid carcinoma cell line (UCLA RO 82 W-1). Virchows Archiv B Cell Pathology 57 167-174.
11. Fabbro D, DiLoreto C, Beltrami CA, Belfiore A, DiLauro R & Damante G 1994 Expression of thyroid specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms. Cancer Research 54 4744-4749.
12. Field JB 1991 Mechanism of action of thyrotropin and other thyroid growth factors. In Werner and Ingbar's The Thyroid, edn 6, pp 276-287. Eds LE Braverman & RD Utiger. Philadelphia: JB Lippincott Co.
13. Francis-Lang H, Price M, Polycarpou-Schwarz M & DiLauro R 1992a Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression. Molecular and Cellular Biology 12 576-588.
14. Francis-Lang H, Zannini M, DeFelice M, Berlingieri MT, Fusco A & DiLauro R 1992b Multiple mechanisms of interference between transformation and differentiation in thyroid cells. Molecular and Cellular Biology 12 5793-5800.
15. Gauthier K, Chassande O, Plateroti M, Roux JP, Legrand C, Pain B, Rousset B, Weiss R, Trouillas J & Samaurt J 1999 Different functions for the thyroid hormone receptors TRα and TRβ in the control of thyroid hormone production and post-natal development. EMBO Journal 18 623-631.
16. Gittoes NJL, McCabe CJ, Verhaeg J, Sheppard MC & Franklyn JA 1998 An abnormality of thyroid hormone receptor expression may explain abnormal thyrotropin production in thyrotropin-secreting pituitary tumors. Thyroid 8 9-14.
17. Kimura S 1997 Role of the thyroid-specific enhancer-binding protein in transcription, development and differentiation. European Journal of Endocrinology 136 128-136.
18. Koenig RJ 1998 Thyroid hormone receptor coactivators and compressors. Thyroid 8 703-713.
19. Kohn LD, Ban T, Okajima F, Shimura H, Shimura Y, Hidaka A, Giuliani C, Napolitano G, Kosugi S, Ikuyama S, Akamizu T, Tahara K & Saji M 1995 Cloning and regulation of glycoprotein hormone receptor genes. In Molecular Endocrinology: Basic Concepts and Clinical Correlations, edn 1, pp 133-153. Ed BD Weintraub. New York: Raven Press Ltd.
20. Lebel JM, Dussault JH & Puymirat J 1994 Overexpression of the β1 thyroid receptor induces differentiation in Neuro-2a cells. Proceedings of the National Academy of Sciences of the USA 91 2644-2648.
21. Lin KH, Willingham MC, Liang CM & Cheng SY 1991 Intracellular distribution of the endogenous and transfected β form of thyroid hormone nuclear receptor visualized by the use of domain-specific monoclonal antibodies. Endocrinology 128 2601-2609.
22. Lin KH, Lin YW, Parkison C & Cheng SY 1994 Stimulation of proliferation by 3,3′,5-triiodo-L-thyronine in poorly differentiated human hepatocarcinoma cells over-expressing β1 thyroid hormone receptor. Cancer Letters 85 189-194.
23. Lin KH, Lin YW, Lee HF, Liu WL, Chen ST, Chang KSS & Cheng SY 1995 Increased invasive activity of human hepatocellular carcinoma cells is associated with an overexpression of thyroid hormone β1 nuclear receptor and low expression of the anti-metastatic nm23 gene. Cancer Letters 98 89-95.
24. Lin KH, Zhu XG, Shieh HY, Hsu HC, Chen ST, McPhie P & Cheng SY 1996 Identification of naturally occurring dominant negative mutants of thyroid hormone α1 and β1 receptors in a human hepatocellular carcinoma cell line. Endocrinology 137 4073-4081.
25. Lin KH, Zhu XG, Hsu HC, Chen SL, Shieh HY, Chen ST, McPhie P & Cheng SY 1997 Dominant negative activity of mutant thyroid hormone α1 receptors from patients with hepatocellular carcinoma. Endocrinology 138 5308-5315.
26. Metcalfe RA, Findlay C, Robertson WR, Weetman AP & MacNeil S 1998 Differential effect of thyroid-stimulating hormone (TSH) on intracellular free calcium and cAMP in cells transfected with the human TSH receptor. Journal of Endocrinology 157 415-424.
27. Moretti F, Farsetti A, Soddu S, Misiti S, Crescenzi M, Filetti S, Andreoli M, Sacchi A & Pontecorvi A 1997 p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells. Oncogene 14 729-740.
28. Munoz A & Bernal J 1997 Biological activities of thyroid hormone receptors. European Journal of Endocrinology 137 433-445.
29. Namba H, Yamashita S, USA T, Kimura H, Yokoyama N, Izumi M & Nagataki S 1993 Overexpression of the intact thyrotropin receptor in a human thyroid cancer cell line. Endocrinology 132 839-845.
30. Ohta K, Endo T & Onaya T 1991 The mRNA levels of thyrotropin receptor, thyroglobulin and thyroid peroxidase in neoplastic human thyroid tissues. Biochemical and Biophysical Research Communications 174 1148-1153.
31. Pastor R, Bernal J & Rodriguez-Pena A 1994 Unliganded c-erbA/thyroid hormone receptor induces trkB expression in neuroblastoma cells. Oncogene 9 1081-1089.
32. Qi JS, Desai-Yajnik V, Yuan Y & Samuels HH 1997 Constitutive-activation of gene expression by thyroid hormone receptor results from reversal of p53-mediated repression. Molecular and Cellular Biology 17 7195-7207.
33. Qi JS, Yuan Y, Desai-Yajnik V & Samuels HH 1999 Regulation of the mdm2 oncogene by thyroid hormone receptor. Molecular and Cellular Biology 19 864-872.
34. Saiardi A, Falasca P & Civitareale D 1994 The thyroid hormone inhibits the thyrotropin receptor promoter activity: evidence for a short loop regulation. Biochemical and Biophysical Research Communications 205 230-237.
35. Sarapura VD, Wood WM, Bright TM, Ocran KW, Gordon DF & Ridgway CR 1997 Reconstitution of triiodothyronine inhibition in non-triiodothyronine-responsive thyrotropic tumor cells using transfected thyroid hormone receptor isoforms. Thyroid 7 453-461.
36. Schneider AB 1991 Carcinoma of follicular epithelium. In Werner and Ingbar's The Thyroid, edn 6, pp 1121-1165. Eds LE Braverman & RD Utiger. Philadelphia: JB Lippincott Co.
37. Schuppert F, Deiters S, Rambusch E, Sierralta W, Dralle H & von zur Muhlen A 1996 TSH-receptor expression and human thyroid disease: relation to clinical, endocrine, and molecular thyroid parameters. Thyroid 6 575-587.
38. Tagami T, Madison LD, Nagaya T & Jameson L 1997 Nuclear receptor compressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone. Molecular and Cellular Biology 17 2642-2648.
39. Zannini M, Francis-Lang H, Plachov D & DiLauro R 1992 Pax 8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters. Molecular and Cellular Biology 12 4230-4241.