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Volumn 35, Issue 3, 2000, Pages 305-315

Structure-apoptotic potency evaluations of novel sterols using human leukemic cells

Author keywords

[No Author keywords available]

Indexed keywords

15 KETOCHOLESTENOL; 15 KETOCHOLESTENOL HYDROXYETHYL ETHER; 25 HYDROXYCHOLESTEROL; 7 KETOCHOLESTEROL HYDROXYETHYL ETHER; CHOLESTEROL DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0034118212     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-000-0527-9     Document Type: Conference Paper
Times cited : (4)

References (37)
  • 1
    • 0027327239 scopus 로고
    • Suppression of c-myc is a critical step in glucocorticoid-induced human leukemic cell lysis
    • Thulasi, R., Harbour, D.V., and Thompson, E.B. (1993) Suppression of c-myc Is a Critical Step in Glucocorticoid-Induced Human Leukemic Cell Lysis, J. Biol. Chem. 268, 18306-18312.
    • (1993) J. Biol. Chem. , vol.268 , pp. 18306-18312
    • Thulasi, R.1    Harbour, D.V.2    Thompson, E.B.3
  • 2
    • 0033540272 scopus 로고    scopus 로고
    • Apoptosis induced by oxysterol in CEM cells is associated with negative regulation of c-myc
    • Ayala-Torres, S., Zhou, F., and Thompson, E.B. (1999) Apoptosis Induced by Oxysterol in CEM Cells Is Associated with Negative Regulation of c-myc, Exper. Cell Res. 246, 193-202.
    • (1999) Exper. Cell Res. , vol.246 , pp. 193-202
    • Ayala-Torres, S.1    Zhou, F.2    Thompson, E.B.3
  • 4
    • 0025987828 scopus 로고
    • Biological activities and physico-chemical studies
    • Luu, B., and Moog, C. (1991) Biological Activities and Physico-chemical Studies, Biochimie 73, 1317-1320.
    • (1991) Biochimie , vol.73 , pp. 1317-1320
    • Luu, B.1    Moog, C.2
  • 6
    • 0028957232 scopus 로고
    • Side-chain oxysterol regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity
    • Parish, E.J., Parish, S.C.,and Li, S. (1995) Side-Chain Oxysterol Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Activity, Lipids 30, 247-251.
    • (1995) Lipids , vol.30 , pp. 247-251
    • Parish, E.J.1    Parish, S.C.2    Li, S.3
  • 9
    • 0026248941 scopus 로고
    • Biological activities of oxygenated sterols: Physiological and pathological implications
    • Hwang, P.L. (1991) Biological Activities of Oxygenated Sterols: Physiological and Pathological Implications, BioEssays 13, 583-589.
    • (1991) BioEssays , vol.13 , pp. 583-589
    • Hwang, P.L.1
  • 10
    • 0029945036 scopus 로고    scopus 로고
    • Review of progress in sterol oxidations: 1987-1995
    • Smith, L.L. (1996) Review of Progress in Sterol Oxidations: 1987-1995, Lipids 31, 453-487.
    • (1996) Lipids , vol.31 , pp. 453-487
    • Smith, L.L.1
  • 11
    • 0025012732 scopus 로고
    • Basic precepts and the lipid hypothesis of atherogenesis
    • Stehbens, W.E. (1990) Basic Precepts and the Lipid Hypothesis of Atherogenesis, Med. Hypotheses 31, 105-113.
    • (1990) Med. Hypotheses , vol.31 , pp. 105-113
    • Stehbens, W.E.1
  • 12
    • 0023727252 scopus 로고
    • The complement system in atherosclerosis
    • Seifert, P.S., and Kazatchkine, M.D. (1988) The Complement System in Atherosclerosis. Atherosclerosis 73, 91-104.
    • (1988) Atherosclerosis , vol.73 , pp. 91-104
    • Seifert, P.S.1    Kazatchkine, M.D.2
  • 13
    • 0030820068 scopus 로고    scopus 로고
    • 7-hydroperoxycholesterol and its products in oxidized low density lipoprotein and human atherosclerotic plaque
    • Brown, A.J., Leong, S.L., Dean, R.T., and Jessup, W. (1997) 7-Hydroperoxycholesterol and Its Products in Oxidized Low Density Lipoprotein and Human Atherosclerotic Plaque, J. Lipid Res. 38, 1730-1745.
    • (1997) J. Lipid Res. , vol.38 , pp. 1730-1745
    • Brown, A.J.1    Leong, S.L.2    Dean, R.T.3    Jessup, W.4
  • 14
    • 0030768928 scopus 로고    scopus 로고
    • Lipoprotein trafficking in vascular cells: Molecular trojan horses and cellular saboteurs
    • Hajjar, D.P., and Haberland, M.D. (1997) Lipoprotein Trafficking in Vascular Cells: Molecular Trojan Horses and Cellular Saboteurs, J. Biol. Chem. 272, 22975-22978.
    • (1997) J. Biol. Chem. , vol.272 , pp. 22975-22978
    • Hajjar, D.P.1    Haberland, M.D.2
  • 15
    • 0342316532 scopus 로고    scopus 로고
    • Oxysterols: Modulators of cholesterol metabolism and other processes - Oxysterols as potential cancer chemotherapeutic agents
    • Schroepfer, G.J., Jr. (1999) Oxysterols: Modulators of Cholesterol Metabolism and Other Processes - Oxysterols as Potential Cancer Chemotherapeutic Agents, Physiol. Rev. 80, 361-554.
    • (1999) Physiol. Rev. , vol.80 , pp. 361-554
    • Schroepfer G.J., Jr.1
  • 16
    • 0027305001 scopus 로고
    • Metabolism of new anticancer oxysterol derivatives in rats
    • Moog, C., Frank, N., Luu, B., and Bertram, B. (1993) Metabolism of New Anticancer Oxysterol Derivatives in Rats, Anticancer Res. 13, 953-958.
    • (1993) Anticancer Res. , vol.13 , pp. 953-958
    • Moog, C.1    Frank, N.2    Luu, B.3    Bertram, B.4
  • 17
    • 0029446145 scopus 로고
    • From cholesterol to oxysterols: Current data
    • Luu, B. (1995) From Cholesterol to Oxysterols: Current Data, C.R. Seances Soc. Biol. Fil. 189, 827-837.
    • (1995) C.R. Seances Soc. Biol. Fil. , vol.189 , pp. 827-837
    • Luu, B.1
  • 18
    • 0030797176 scopus 로고    scopus 로고
    • Cytotoxic properties of a phosphoglycoconjugated derivative of 7-beta-hydroxycholesterol upon normal and tumor cells in culture
    • Hyun, J.W., Weltin, D., Holl, V., Marchal, J., Dufour, P., Luu, B., and Bischoff, P. (1997) Cytotoxic Properties of a Phosphoglycoconjugated Derivative of 7-beta-Hydroxycholesterol upon Normal and Tumor Cells in Culture. Anticancer Res. 17, 2621-2626.
    • (1997) Anticancer Res. , vol.17 , pp. 2621-2626
    • Hyun, J.W.1    Weltin, D.2    Holl, V.3    Marchal, J.4    Dufour, P.5    Luu, B.6    Bischoff, P.7
  • 19
    • 0031586358 scopus 로고    scopus 로고
    • Characteristics of 25-hydroxycholesterol-induced apoptosis in the human leukemic cell line CEM
    • Ayala-Torres, S., Moller, P.C., Johnson, B.H., and Thompson, E.B. (1997) Characteristics of 25-Hydroxycholesterol-Induced Apoptosis in the Human Leukemic Cell Line CEM, Exper. Cell Res. 235, 35-47.
    • (1997) Exper. Cell Res. , vol.235 , pp. 35-47
    • Ayala-Torres, S.1    Moller, P.C.2    Johnson, B.H.3    Thompson, E.B.4
  • 20
    • 0027383353 scopus 로고
    • Oxysterol-induced cell death in human leukemic T-cells correlates with oxysterol binding protein occupancy and is independent of glucocorticoid-induced apoptosis
    • Bakos, J.T., Johnson, B.H., and Thompson, E.B. (1993) Oxysterol-Induced Cell Death in Human Leukemic T-Cells Correlates with Oxysterol Binding Protein Occupancy and Is Independent of Glucocorticoid-Induced Apoptosis, J. Steroid Biochem. Molec. Biol. 46, 415-426.
    • (1993) J. Steroid Biochem. Molec. Biol. , vol.46 , pp. 415-426
    • Bakos, J.T.1    Johnson, B.H.2    Thompson, E.B.3
  • 21
    • 0030600377 scopus 로고    scopus 로고
    • Oxysterols induced apoptosis in cultured smooth muscle cells through CPP32 protease activation and Bcl-2 protein downregulation
    • Nishio, E., and Watanabe, Y. (1996) Oxysterols Induced Apoptosis in Cultured Smooth Muscle Cells Through CPP32 Protease Activation and Bcl-2 Protein Downregulation, Biochem. Biophys. Res. Com. 226, 928-934.
    • (1996) Biochem. Biophys. Res. Com. , vol.226 , pp. 928-934
    • Nishio, E.1    Watanabe, Y.2
  • 23
    • 0031464053 scopus 로고    scopus 로고
    • Induction of apoptosis and of interleukin-1 beta secretion by 7 beta-hydroxycholesterol and 7-ketocholes-terol: Partial inhibition by Bcl-2 over-expression
    • Lizard, G., Lemaire, S., Monier, S., Gueldry, S., Neel, D., and Gambert, P. (1997) Induction of Apoptosis and of Interleukin-1 beta Secretion by 7 beta-Hydroxycholesterol and 7-Ketocholes-terol: Partial Inhibition by Bcl-2 Over-expression, FEBS Lett. 419, 276-280.
    • (1997) FEBS Lett. , vol.419 , pp. 276-280
    • Lizard, G.1    Lemaire, S.2    Monier, S.3    Gueldry, S.4    Neel, D.5    Gambert, P.6
  • 24
    • 0017663695 scopus 로고
    • Characterization of a glucocorticoid-sensitive human lymphoid cell line
    • Norman, M.R., and Thompson, E.B. (1977) Characterization of a Glucocorticoid-sensitive Human Lymphoid Cell Line, Cancer Res. 37, 3785-3791.
    • (1977) Cancer Res. , vol.37 , pp. 3785-3791
    • Norman, M.R.1    Thompson, E.B.2
  • 25
    • 0002569886 scopus 로고
    • Dye exclusion tests for cell viability
    • Kruse, M.K., Jr., and Patterson, P.F., Jr., eds., Academic Press, New York
    • Philips, H.J. (1973) Dye Exclusion Tests for Cell Viability, in Tissue Culture: Methods and Applications (Kruse, M.K., Jr., and Patterson, P.F., Jr., eds.), pp. 406-408, Academic Press, New York.
    • (1973) Tissue Culture: Methods and Applications , pp. 406-408
    • Philips, H.J.1
  • 27
    • 0026737347 scopus 로고
    • Accelerated programmed cell death of MRL-1pr/1pr T lymphocytes
    • Van Houten, N., and Budd, R.C. (1992) Accelerated Programmed Cell Death of MRL-1pr/1pr T lymphocytes, J. Immunol. 149, 2513-2517.
    • (1992) J. Immunol. , vol.149 , pp. 2513-2517
    • Van Houten, N.1    Budd, R.C.2
  • 28
    • 0026465103 scopus 로고
    • Prediction of response to drug therapy of cancer: A review of in vitro assays
    • Bellamy, W.T. (1992) Prediction of Response to Drug Therapy of Cancer: A Review of In Vitro Assays, Drugs 44, 690-708.
    • (1992) Drugs , vol.44 , pp. 690-708
    • Bellamy, W.T.1
  • 29
    • 0021260784 scopus 로고
    • Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation
    • Vitols, S., Gahrton, F., Ost, A., and Peterson, C. (1984) Elevated Low Density Lipoprotein Receptor Activity in Leukemic Cells with Monocytic Differentiation, Blood 63, 1186-1193.
    • (1984) Blood , vol.63 , pp. 1186-1193
    • Vitols, S.1    Gahrton, F.2    Ost, A.3    Peterson, C.4
  • 30
    • 0021265487 scopus 로고
    • Significance of the Low-Density Lipoprotein (LDL) receptor pathway for the in vitro accumulation of AD-32 incorporated into LDL in normal and leukemic white blood cells
    • Vitols, S., Gahrton G., and Peterson, C. (1984) Significance of the Low-Density Lipoprotein (LDL) Receptor Pathway for the in vitro Accumulation of AD-32 Incorporated into LDL in Normal and Leukemic White Blood Cells, Cancer Treat. Rep. 68, 515-520.
    • (1984) Cancer Treat. Rep. , vol.68 , pp. 515-520
    • Vitols, S.1    Gahrton, G.2    Peterson, C.3
  • 32
    • 0026251048 scopus 로고
    • Cholesterol content but not plasma membrane fluidity influences the susceptibility of L1210 leukemic cells to merocyanine 540-sensitized irradiation
    • Gaffney, D.K., Feix, J.B., Schwarz, H.P., Stuve, M.F., and Sieber, F. (1991) Cholesterol Content but Not Plasma Membrane Fluidity Influences the Susceptibility of L1210 Leukemic Cells to Merocyanine 540-Sensitized Irradiation, Photochem. Photobiol. 54, 717-723.
    • (1991) Photochem. Photobiol. , vol.54 , pp. 717-723
    • Gaffney, D.K.1    Feix, J.B.2    Schwarz, H.P.3    Stuve, M.F.4    Sieber, F.5
  • 33
    • 0021747172 scopus 로고
    • Correlation between oxysterol binding to a cytosolic binding protein and potency in the repression of hydroxymethylglutaryl coenzyme A reductase
    • Taylor, F.R., Saucier, S.E., Shown, E.P., Parish, E.J., and Kandutsch, A.A. (1984) Correlation Between Oxysterol Binding to a Cytosolic Binding Protein and Potency in the Repression of Hydroxymethylglutaryl Coenzyme A Reductase, J. Biol. Chem. 259, 12382-12387.
    • (1984) J. Biol. Chem. , vol.259 , pp. 12382-12387
    • Taylor, F.R.1    Saucier, S.E.2    Shown, E.P.3    Parish, E.J.4    Kandutsch, A.A.5
  • 35
    • 11944268807 scopus 로고
    • Role of oxysterols in the regulation of cholesterol homeostasis: A critical evaluation
    • Lund, E., and Bjorkhem, I. (1995) Role of Oxysterols in the Regulation of Cholesterol Homeostasis: A Critical Evaluation, Accounts Chem. Res. 28, 241-249.
    • (1995) Accounts Chem. Res. , vol.28 , pp. 241-249
    • Lund, E.1    Bjorkhem, I.2
  • 36
    • 0025202968 scopus 로고
    • Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis
    • Sinensky, M., Beck, L.A., Leonard, S., and Evans, R. (1990) Differential Inhibitory Effects of Lovastatin on Protein Isoprenylation and Sterol Synthesis, J. Biol. Chem. 265, 19937-19941.
    • (1990) J. Biol. Chem. , vol.265 , pp. 19937-19941
    • Sinensky, M.1    Beck, L.A.2    Leonard, S.3    Evans, R.4
  • 37
    • 0030609811 scopus 로고    scopus 로고
    • 7 alpha-hydroxylation and 3-dehydrogenation abolish the ability of 25-hydroxycholesterol and 27-hydroxycholesterol to induce apoptosis in thymocytes
    • Zhang, J., Xue, Y., Jondal, M., and Sjovall, J. (1997) 7 Alpha-hydroxylation and 3-Dehydrogenation Abolish the Ability of 25-Hydroxycholesterol and 27-Hydroxycholesterol to Induce Apoptosis in Thymocytes. Eur. J. Biochem. 247, 129-135.
    • (1997) Eur. J. Biochem. , vol.247 , pp. 129-135
    • Zhang, J.1    Xue, Y.2    Jondal, M.3    Sjovall, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.