Modulation of synaptic transmission in the rat ventral septal area by the pharmacological activation of metabotropic glutamate receptors

European Journal of Neuroscience

Volumn 12, Issue 5, 2000, Pages 1843-1847

  Tolchard, Stephen ^a   Clarke, Geoff ^a   Collingridge, Graham L ^a   Fitzjohn, Stephen M ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

DCG IV; DHPG; L AP4; mGlu receptor; NMDA; Septum

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; 2 AMINO 5 PHOSPHONOVALERIC ACID; 3,5 DIHYDROXYPHENYLGLYCINE; GLUTAMATE RECEPTOR AGONIST; GLYCINE DERIVATIVE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; SEPTUM PELLUCIDUM; SYNAPTIC TRANSMISSION;

2-AMINO-5-PHOSPHONOVALERATE; ANIMALS; CYCLOPROPANES; EXCITATORY POSTSYNAPTIC POTENTIALS; GLYCINE; METHOXYHYDROXYPHENYLGLYCOL; PATCH-CLAMP TECHNIQUES; PICROTOXIN; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; SEPTUM OF BRAIN; SYNAPTIC TRANSMISSION;

EID: 0034117392     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2000.00080.x     Document Type: Article

References (27)

1. Anwyl, R. (1999) Metabotropic glutamate receptors: electrophysiological properties and role in plasticity. Brain Res. Rev., 29, 83-120.
2. Anderson, W.W. & Collingridge, G.L. (1997) A data acquisition program for on-line analysis of long-term potentiation and long-term depression. Soc. Neurosci. Abstr., 264, 19.
3. Breakwell, N.A., Huang, L., Rowan, M.J. & Anwyl, R. (1997) DCG-IV inhibits synaptic transmission by activation of NMDA receptors in area CA1 of the rat hippocampus. Eur. J. Pharmacol., 322, 173-178.
4. Bushell, T.J., Jane, D.E., Tse, H., Watkins, J.C., Garthwaite, J. & Collingridge, G.L. (1996) Pharmacological antagonism of the actions of group II and III mGluR agonists in the lateral perforant path of rat hippocampal slices. Br. J. Pharmacol., 117, 1457-1462.
5. Conn, P.J. & Pin, J.-P. (1997) Pharmacology and functions of metabotropic glutamate receptors. Annu. Rev. Pharmacol. Toxicol., 37, 205-237.
6. Disturnal, J.E., Veale, W.L. & Pittman, Q.J. (1986) The ventral septal area: Electrophysiological evidence for putative arginine vasopressin projections onto thermoresponsive neurones. Neuroscience, 19, 795-802.
7. Disturnal, J.E., Veale, W.L. & Pittman, Q.J. (1987) Modulation by arginine-vasopressin of glutamate excitation in the ventral septal area of the rat brain. Can. J. Physiol., 65, 30-35.
8. Fitzjohn, S.M., Irving, A.J., Palmer, M.J., Harvey, J., Lodge, D. & Collingridge, G.L. (1996a) Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices. Neurosci. Lett., 203, 211-213.
9. Fitzjohn, S.M., Lodge, D. & Collingridge, G.L. (1996b) Long-term depression of synaptic transmission induced by group I metabotropic glutamate receptor activation in the CA1 of young rat hippocampus. J. Physiol. (Paris), 90, 410-411.
10. Fitzjohn, S.M., Kingston, A.E., Lodge, D. & Collingridge, G.L. (1999) DHPG-induced LTD in area CA1 of juvenile rat hippocampus; characterisation and sensitivity to novel mGlu receptor antagonists. Neuropharmacology, 38, 1577-1583.
11. Gereau, R. & Conn, J. (1995) Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1. J. Neurosci., 15, 6879-6889.
12. Hölscher, C., Anwyl, R. & Rowan, M.J. (1997) Activation of group II metabotropic receptors blocks induction of long-term potentiation and depotentiation in area CA1 of the rat in vivo. Eur. J. Pharmacol., 322, 155-163.
13. Huang, L., Rowan, M.J. & Anwyl, R. (1997) mGluR II agonist inhibition of LTP induction, and mGluR II antagonist inhibition of LTD induction, in the dentate gyrus in vitro. Neuroreport, 8, 687-693.
14. Huang, L., Kilbride, J., Rowan, M.J. & Anwyl, R. (1999) Activation of mGluRII induces LTD via activation of protein kinase A and protein kinase C in the dentate gyrus of the hippocampus in vitro. Neuropharmacology, 38, 73-83.
15. Kastings, N.W. (1989) Criteria for establishing a physiological role for brain peptides. A case in point: the role of vasopressin in thermoregulation during fever and antipyresis. Brain Res. Rev., 14, 143-153.
16. Kilbride, J., Huang, L.Q., Rowan, M.J. & Anwyl, R. (1998) Presynaptic inhibitory action of the group II metabotropic glutamate receptor agonists, LY354740 and DCG-IV. Eur. J. Pharmacol., 356, 149-157.
17. Macek, T.A., Winder, D.G., Gereau, R.W., Ladd, C.O. & Conn, P.J. (1996) Differential involvement of group I and group II mGluRs as autoreceptors at lateral and medial perforant path syanpses. J. Neurophysiol., 76, 3798-3806.
18. Manahan-Vaughan, D. (1997) Group 1 and group 2 metabotropic glutamate receptors play differential roles in hippocampal long-term depression and long-term potentiation in freely moving rats. J. Neurosci., 17, 3303-3311.
19. Nakanishi, S. & Masu, M. (1994) Molecular diversity and functions of glutamate receptors. Annu. Rev. Biophys. Biomol. Struc., 23, 319-348.
20. Neugebauer, V., Keele, N.B. & Shinnick-Gallagher, P. (1997) Loss of long-lasting potentiaion mediated by group III mGluRs in amygdala neurons in kindling-induced epilepsy. J. Neurophysiol., 78, 3475-3478.
21. Palmer, M.J., Irving, A.J., Seabrook, G.R., Jane, D.E. & Collingridge, G.L. (1997) The group 1 mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus. Neuropharmacology. 36, 1517-1532.
22. Pittman, Q.J., Poulin, P. & Wilkinson, M.F. (1993) The role of neurohypophyseal hormones in temperature regulation. Ann. NY Acad. Sci., 689, 375-381.
23. Reymann, K.G. & Matthies, H. (1989) 2-amino-4-phosphonobutyrate selectively eliminates the late phases of long-term potentiation in the rat hippocampus. Neurosci. Lett., 98, 166-171.
24. Tolchard, S. & Collingridge, G.L. (1997) Synaptic plasticity in the ventral septal area (VSA) of juvenille rats in vitro induced by activation of metabotropic glutamate receptors. J. Physiol., 504, 212P.
25. Young, A.B. & Fagg, G.E. (1990) Excitatory amino acid receptors in the brain: Membrane binding and receptor autoradiographic approaches. Trends Pharmacol. Sci., 11, 126-133.
26. Yokoi, M., Kobayashi, K., Manabe, T., Takahashi, T., Sakaguchi, I., Katsuura, G., Shigemoto, R., Ohishi, H., Nomura, S., Nakamura, K., Nakao, K., Katsuki, M. & Nakanishi, S. (1996) Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2. Science, 273, 645-647.
27. Zheng, F. & Gallagher, J.P. (1992) Metabotropic glutamate receptors are required for the induction of long-term potentiation. Neuron, 9, 163-172.