In vitro activity of RU 64004, a new ketolide antibiotic, against gram- positive bacteria

Antimicrobial Agents and Chemotherapy

Volumn 41, Issue 5, 1997, Pages 1196-1202

  Schulin T ^a,b   Wennersten, C B ^a   Moellering Jr , R C ^a,b   Eliopoulos, G M ^a,b,c  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c West Campus   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CLARITHROMYCIN; CLINDAMYCIN; DALFOPRISTIN; ERYTHROMYCIN; HMR 3004; MACROLIDE; OXACILLIN; ROXITHROMYCIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ALPHA HEMOLYTIC STREPTOCOCCUS; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; DRUG POTENCY; ENTEROCOCCUS FAECALIS; GRAM POSITIVE BACTERIUM; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS AGALACTIAE; STREPTOCOCCUS GROUP A; STREPTOCOCCUS GROUP C;

EID: 0343742636     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.5.1196     Document Type: Article

References (10)

1. Agouridas, C., Y. Benedetti, A. Denis, O. Le Martrel, and J. F. Chantot. 1995. Ketolides: a new distinct class of macrolide antibacterials - synthesis and structural characteristics of RU 004, abstr. F157, p. 140. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy American Society for Microbiology, Washington, D.C.
2. Agouridas, C., A. Bonnefoy, and J. F. Chantot. 1995. In vitro antibacterial activity of RU 004, a novel ketolide highly active against respiratory pathogens, abstr. F158, p. 140. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology Washington, D.C.
3. Agouridas, C., A. Bonnefoy, and J. F. Chantot. 1995. In vivo antibacterial activity of RU 004, a novel kelolide highly active against respiratory pathogens, abstr. F171, p. 143. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
4. Ednie, L., M. R. Jacobs, and P. C. Appelbaum. 1995. Activity of the ketolide RU 004 compared to 15 other agents against 112 erythromycin susceptible and resistant pneumococci, abstr. F159, p. 141. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
5. Fremaux, A., G. Sissia, J. F. Chantot, and P. Geslin. 1995. Antibacterial activity of the ketolide RU 004 against multi-resistant pneumococci, abstr. F160, p. 141. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
6. Murray, B. E. 1990. The life and times of the enterococcus. Clin. Microbiol. Rev. 3:46-65.
7. National Committee for Clinical Laboratory Standards. 1993. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically, 3rd ed. Approved standard. National Committee for Clinical Laboratory Standards document M7-A3. National Committee for Clinical Laboratory Standards, Villanova, Pa.
8. Rosato, A., and R. Leclercq. 1995. Regulation of the msrA gene responsible for inducible resistance to erythromycin by active efflux in Staphylococcus epidermidis, abstr. C112, p. 59. In Abstracts of the 35th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
9. Ross, J. I., A. M. Farrell, E. A. Eady, J. H. Cove, and W. J. Cunliffe. 1989. Characterisation and molecular cloning of the novel macrolide-streptogramin B resistance determinant from Staphylococcus epidermidis. J. Antimicrob. Chemother. 24:851-862.
10. Schülin, T., C. B. Wennersten, G. M. Eliopoulos, and R. C. Moellering, Jr. 1996. In vitro activity of RU 64004, a new ketolide antibiotic against grampositive bacteria, abstr. F220, p. 138. In Abstracts of the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.