Mineralocorticoid selectivity: Molecular and cellular aspects

Kidney International

Volumn 57, Issue 4, 2000, Pages 1364-1369

  Farman, Nicolette ^a   Bocchi, Brigitte ^a  

^a INSERM   (France)

Author keywords

11 HSD2; Aldosterone; Glucocorticoid hormones; Hypertension; Mineralocorticoid receptor

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ALDOSTERONE; CARBENOXOLONE; CORTICOSTERONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLYCYRRHETINIC ACID; HYDROCORTISONE; MINERALOCORTICOID; MINERALOCORTICOID RECEPTOR; SODIUM CHANNEL; VASOPRESSIN;

BLOOD PRESSURE REGULATION; CONFERENCE PAPER; ENZYME ACTIVITY; HEART MUSCLE CELL; HORMONE ACTION; HUMAN; HYPERTENSION; KIDNEY COLLECTING TUBULE; NONHUMAN; PRIORITY JOURNAL; SYNDROME; TRANSCRIPTION REGULATION;

EID: 0034115541     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2000.00976.x     Document Type: Conference Paper

References (52)

1. 1. BONVALET JP: Regulation of sodium transport by steroid hormones. Kidney Int 53:S49-S56, 1998
2. 2. VERREY F: Transcriptional control of sodium transport in tight epithelia by adrenal steroids. J Membr Biol 144:93-110, 1995
3. 3. FUNDER JW: Glucocorticoid and mineralocorticoid receptors: Biology and clinical relevance. Annu Rev Med 48:231-240, 1997
4. 4. MANGELSDORF DJ, THUMMEL C, BEATO M, HERRLICH P, SCHUTZ G, UMESONO K, BLUMBERG B, KASTNER P, MARK M, CHAMBON P, EVANS RM: Overview: The nuclear receptor superfamily: The second decade. Cell 83:835-839, 1995
5. 5. FARMAN N, VANDEWALLE A, BONVALET JP: Aldosterone binding in isolated tubules. I. Biochemical determination in proximal and distal parts of the rabbit nephron. Am J Physiol 242:F63-F68, 1982
6. 6. FARMAN N, OBLIN ME, LOMBES M, DELAHAYE F, WESTPHAL HM, BONVALET JP, GASC JM: Immunolocalization of gluco and mineralocorticoid receptors in the rabbit kidney. Am J Physiol 260:C226-C233, 1991
7. 7. EDWARDS CRW, STEWART PM, BURT D, BRET L, MCINTYRE MA, SUTANTO WS, DE KLOET ER, MONDER C: Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor. Lancet 2:986-989, 1988
8. 8. FUNDER JW, PEARCE PT, SMITH R, SMITH AI: Mineralocorticoid action: Target tissue specificity is enzyme, not receptor, mediated. Science 242:583-585, 1988
9. 9. FARMAN N: Molecular and cellular determinants of mineralocorticoid selectivity. Curr Opin Nephrol Hypertens 8:45-51, 1999
10. 10. FUNDER JW: Apparent mineralocorticoid excess, 11 beta hydroxysteroid dehydrogenase and aldosterone action: Closing one loop, opening another. Trends Endocrinol Metab 6:248-251, 1995
11. 11. OPPERMANN UCT, PERSSON B, JORNVALL H: The 11-beta-hydroxysteroid dehydrogenase system, a determinant of glucocorticoid and mineralocorticoid action: Function, gene organization and protein structures of 11-beta-hydroxysteroid dehydrogenase isoforms. Eur J Biochem 249:355-360, 1997
12. 12. SECKL JR, CHAPMAN KE: The 11-beta-hydroxysteroid dehydrogenase system, a determinant of glucocorticoid and mineralocorticoid action: Medical and physiological aspects of the 11-beta-hydroxysteroid dehydrogenase system. Eur J Biochem 249:361-364, 1997
13. 13. STEWART PM, KROZOWSKI ZS: 11 beta-hydroxysteroid dehydrogenase. Vitam Horm 57:249-324, 1999
14. 14. FARMAN N, BONVALET JP: Aldosterone binding in isolated tubules. III. Autoradiography along the rat nephron. Am J Physiol 245:F606-F614, 1983
15. 15. BONVALET JP, DOIGNON I, BLOT-CHABAUD M, PRADELLES P, FARMAN N: Distribution of 11beta-hydroxysteroid dehydrogenase along the rabbit nephron. J Clin Invest 86:832-837, 1990
16. 16. HIRASAWA G, SASANO H, TAKAHASHI KI, FUKUSHIMA K, SUZUKI T, HIWATASHI N, TOYOTA T, KROZOWSKI ZS, NAGURA H: Colocalization of 11-beta-hydroxysteroid dehydrogenase type II and mineralocorticoid receptor in human epithelia. J Clin Endocrinol Metab 82:3859-3863, 1997
17. 17. KENOUCH S, COUTRY N, FARMAN N, BONVALET JP: Multiple patterns of 11β-hydroxysteroid dehydrogenase catalytic activity along the mammalian ncphron. Kidney Int 42:56-60, 1992
18. 18. KENOUCH S, ALFAIDY N, BONVALET JP, FARMAN N: Expression of 11-HSD along the nephron of mammals and humans. Steroids 59:100-104, 1994
19. 19. NARAY-FEJES-TOTH A, WALLINGTON CO, FEJES-TOTH G: 11beta-hydroxysteroid dehydrogenase activity in the renal target cells of aldosterone. Endocrinology 129:17-21, 1991
20. 20. NARAY-FEJES-TOTH A, FEJES-TOTH G: 11-Beta-hydroxysteroid dehydrogenase-2 is a high affinity corticosterone-binding protein. Mol Cell Endocrinol 134:157-161, 1997
21. 21. RUSVAI E, NARAY-FEJES-TOTH A: A new isoform of 11-beta-hydroxysteroid dehydrogenase in aldosterone target cells. J Biol Chem 268:10717-10720, 1993
22. 22. KENOUCH S, LOMBES M, DELAHAYE F, EUGENE E, BONVALET JP, FARMAN N: Human skin as target for aldosterone: Coexpression of mineralocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase. J Clin Endocrinol Metab 79:1334-1341, 1994
23. 23. SHIMOJO M, RICKETTS ML, PETRELLI MD, MORADI P, JOHNSON GD, BRADWELL AR, HEWISON M, HOWIE AJ, STEWART PM: Immunodetection of 11 beta-hydroxysteroid dehydrogenase type 2 in human mineralocorticoid target tissues: Evidence for nuclear localization. Endocrinology 138:1305-1311, 1997
24. 24. LOMBES M, OBLIN ME, GASC JM, BAULIEU EE, FARMAN N, BONVALET JP: Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor. Circ Res 71:503-510, 1992
25. 25. LOMBES M, ALFAIDY N, EUGENE E, LESSANA A, FARMAN N, BONVALET JP: Prerequisite for cardiac aldosterone action: Mineralocorticoid receptor and 11β-hydroxysteroid dehydrogenase in the human heart. Circulation 92:175-182, 1995
26. 26. ALFAIDY N, BLOT-CHABAUD M, ROBIC D, KENOUCH S, BOURBOUZE R, BONVALET JP, FARMAN N: Characteristics and regulation of 11 beta-hydroxysteroid dehydrogenase of proximal and distal nephron. Biochim Biophys Acta 1243:461-468, 1995
27. 27. ARRIZA JL, SIMERLY RB, SWANSON LW, EVANS RM: The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response. Neuron 1:887-900, 1988
28. 28. HERMAN JP, PATEL PD, AKIL H, WATSON SJ: Localization and regulation of glucocorticoid and mineralocorticoid receptor messenger RNAs in the hippocampal formation of the rat. Mol Endocrinol 3:1886-1894, 1989
29. 29. JOELS M, DE KLOET ER: Corticosteroid hormones: Endocrine messengers in the brain. N Physiol Sci 10:71-76, 1995
30. 30. REUL JMHM, PEARCE PT, FUNDER JW, KROZOWSKI ZS: Type I and type II corticosteroid receptor gene expression in the rat: Effect of adrenalectomy and dexamethasone administration. Mol Endocrinol 3:1674-1680, 1989
31. 31. SECKL JR: Review: 11-Beta-hydroxysteroid dehydrogenase isoforms and their implications for blood pressure regulation. Eur J Clin Invest 23:589-601, 1993
32. 32. AGARWAL AK, MONDER C, ECKSTEIN B, WHITE PC: Cloning and expression of rat cDNA encoding corticosteroid 11β-dehydrogenase. J Biol Chem 264:18939-18943, 1989
33. 33. AGARWAL AK, MUNE T, MONDER C, WHITE PC: NAD(+)-dependent isoform of 11 beta-hydroxysteroid dehydrogenase: Cloning and characterization of cDNA from sheep kidney. J Biol Chem 269:25959-25962, 1994
34. 34. ALBISTON AL, OBEYESEKERE VR, SMITH RE, KROZOWSKI ZS: Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 105:R11-R17, 1994
35. 35. PENNING TM: Molecular endocrinology of hydroxysteroid dehydrogenases. Endocr Rev 18:281-305, 1997
36. 36. OBEYESEKERE VR, LI KXZ, FERRARI P, KROZOWSKI Z: Truncation of the N-and C-terminal regions of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme and effects on solubility and bidirectional enzyme activity. Mol Cell Endocrinol 131:173-182, 1997
37. 37. NARAY-FEJES-TOTH A, FEJES-TOTH G: Subcellular localization of the type 2, 11 beta-hydroxysteroid dehydrogenase: A green fluorescent protein study. J Biol Chem 271:15436-15442, 1996
38. 38. KYOSSEV ZN, REEVES WB: N-glycosylation is not essential for enzyme activity of 11 beta-hydroxysteroid dehydrogenase type 2. Kidney Int 52:682-686, 1997
39. 39. WHITE PC, MUNE T, AGARWAL AK: 11 beta-hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr Rev 18:135-156, 1997
40. 40. KOTELEVTSEV Y, BROWN RW, FLEMING S, KENYON C, EDWARDS CRW, SECKL JR, MULLINS JJ: Hypertension in mice lacking 11β-hydroxysteroid dehydrogenase type 2. J Clin Invest 103:683-689, 1999
41. 41. ALFAIDY N, BLOT-CHABAUD M, BONVALET JP, FARMAN N: Vasopressin potentiates mineralocorticoid selectivity by stimulating 11 beta hydroxysteroid deshydrogenase in rat collecting duct. J Clin Invest 100:2437-2442, 1997
42. 42. HAWK CT, LI L, SCHAFER JA: AVP and aldosterone at physiological concentrations have synergistic effects on Na transport in rat CCD. Kidney Int 50:S35-S41, 1996
43. 43. COUETTE B, FAGART J, JALAGUIER S, LOMBES M, SOUQUE A, RAFESTIN-OBLIN ME: The ligand induced conformational change of the mineralocorticoid receptor occurs within its heterooligomeric structure. Biochem J 315:421-427, 1996
44. 44. FUNDER J, MYLES K: Exclusion of corticosterone from epithelial mineralocorticoid receptors is insufficient for selectivity of aldosterone action: In vivo binding studies. Endocrinology 137:5264-5268, 1996
45. 45. LOMBES M, KENOUCH S, SOUQUE A, FARMAN N, RAFESTIN-OBLIN ME: The mineralocorticoid receptor discriminates aldosterone from glucocorticoids independently of the 11 beta-hydroxysteroid dehydrogcnase. Endocrinology 135:834-840, 1994
46. 46. LOMBES M, BINART N, DELAHAYE F, BAULIEU EE, RAFESTIN-OBLIN ME: Differential intracellular localization of human mineralocorticosteroid receptor on binding of agonists and antagonists. Biochem J 302:191-197, 1994
47. 47. FAGART J, WURTZ JM, SOUQUE A, HELLAL-LEVY C, MORAS D, RAFESTIN-OBLIN ME: Antagonism in the human mineralocorticoid receptor. EMBO J 17:3317-3325, 1998
48. 48. ARRIZA JL, WEINBERGER C, CERELLI G, GLASER TM, HANDELIN BL, HOUSMAN DE, EVANS RM: Cloning of human mineralocorticoid receptor complementary DNA: Structural and functional kinship with the glucocorticoid receptor. Science 237:268-275, 1987
49. 49. TRAPP T, HOLSBOER F: Heterodimerization between mineralocorticoid and glucocorticoid receptors increases the functional diversity of corticosteroid action. Trends Pharmacol Sci 17:145-149, 1996
50. 50. ESCOUBET B, COUREAU C, BONVALET JP, FARMAN N: Noncoordinate regulation of epithelial Na channel and Na pump subunit mRNAs in kidney and colon by aldosterone. Am J Physiol 272:C1482-C1491, 1997
51. 51. DJELIDI S, FAY M, CLUZEAUD F, ESCOUBET B, EUGENE E, CAPURRO C, BONVALET JP, FARMAN N, BLOT-CHABAUD M: Transcriptional regulation of sodium transport by vasopressin in renal cells. J Biol Chem 272:32919-32924, 1997
52. 52. JOHNSON JP: Cellular mechanisms of action of mineralocorticoid hormones. Pharmacol Ther 53:1-29, 1992