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Volumn 68, Issue 6, 2000, Pages 3491-3501

Identification of potential vaccine and drug target candidates by expressed sequence tag analysis and immunoscreening of Onchocerca volvulus larval cDNA libraries

Author keywords

[No Author keywords available]

Indexed keywords

HORMONE RECEPTOR; PROTEINASE; PROTEINASE INHIBITOR; VACCINE;

EID: 0034115183     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.6.3491-3501.2000     Document Type: Article
Times cited : (85)

References (83)
  • 2
    • 0031947155 scopus 로고    scopus 로고
    • daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans
    • Antebi, A., J. G. Culotti, and E. M. Hedgecock. 1998. daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans. Development 125:1191-1205.
    • (1998) Development , vol.125 , pp. 1191-1205
    • Antebi, A.1    Culotti, J.G.2    Hedgecock, E.M.3
  • 3
    • 0021453880 scopus 로고
    • The isoinhibitors of chymotrypsin/elastase from Ascaris lumbricoides: The primary structure
    • Babin, D. R., R. J. Peanasky, and S. M. Goos. 1984. The isoinhibitors of chymotrypsin/elastase from Ascaris lumbricoides: the primary structure. Arch. Biochem. Biophys. 232:143-161.
    • (1984) Arch. Biochem. Biophys. , vol.232 , pp. 143-161
    • Babin, D.R.1    Peanasky, R.J.2    Goos, S.M.3
  • 4
    • 0033169088 scopus 로고    scopus 로고
    • The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor
    • Bamber, B. A., A. A. Beg, R. E. Twyman, and E. M. Jorgensen. 1999. The Caenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptor. J. Neurosci. 19:5348-5359.
    • (1999) J. Neurosci. , vol.19 , pp. 5348-5359
    • Bamber, B.A.1    Beg, A.A.2    Twyman, R.E.3    Jorgensen, E.M.4
  • 6
    • 0026811978 scopus 로고
    • Motor proteins for cytoplasmic microtubules
    • Bloom, G. S. 1992. Motor proteins for cytoplasmic microtubules. Curr. Opin. Cell Biol. 4:66-73.
    • (1992) Curr. Opin. Cell Biol. , vol.4 , pp. 66-73
    • Bloom, G.S.1
  • 8
    • 0032033513 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model for parasitic nematodes
    • Burglin, T. R., E. Lobos, and M. L. Blaxter. 1998. Caenorhabditis elegans as a model for parasitic nematodes. Int. J. Parasitol. 28:395-411.
    • (1998) Int. J. Parasitol. , vol.28 , pp. 395-411
    • Burglin, T.R.1    Lobos, E.2    Blaxter, M.L.3
  • 9
    • 0032511983 scopus 로고    scopus 로고
    • The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex
    • Carmi, I., J. B. Kopczynski, and B. J. Meyer. 1998. The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex. Nature 396:168-173.
    • (1998) Nature , vol.396 , pp. 168-173
    • Carmi, I.1    Kopczynski, J.B.2    Meyer, B.J.3
  • 10
    • 0028120926 scopus 로고
    • Identification and characterisation of a novel repetitive antigen from Onchocerca spp
    • Catmull, J., D. Zhang, F. Ruggiero, D. B. Copeman, and D. J. Miller. 1994. Identification and characterisation of a novel repetitive antigen from Onchocerca spp. Mol. Biochem. Parasitol. 63:49-57.
    • (1994) Mol. Biochem. Parasitol. , vol.63 , pp. 49-57
    • Catmull, J.1    Zhang, D.2    Ruggiero, F.3    Copeman, D.B.4    Miller, D.J.5
  • 11
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: A platform for investigating biology
    • The C. elegans Sequencing Consortium. 1998. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282:2012-2018.
    • (1998) Science , vol.282 , pp. 2012-2018
  • 12
    • 0029023250 scopus 로고
    • Molecular characterization of a parasite antigen in sera from onchocerciasis patients that is immunologically cross-reactive with human keratin
    • Chandrashekar, R., K. C. Curtis, and G. J. Weil. 1995. Molecular characterization of a parasite antigen in sera from onchocerciasis patients that is immunologically cross-reactive with human keratin. J. Infect. Dis. 171:1586-1592.
    • (1995) J. Infect. Dis. , vol.171 , pp. 1586-1592
    • Chandrashekar, R.1    Curtis, K.C.2    Weil, G.J.3
  • 13
    • 0010726063 scopus 로고
    • Cyclosporin A: Antiparasite drug, modulator of the host-parasite relationship and immunosuppressant
    • Chappell, L. H., and J. M. Wastling. 1992. Cyclosporin A: antiparasite drug, modulator of the host-parasite relationship and immunosuppressant. Parasitology 105:S25-S40.
    • (1992) Parasitology , vol.105
    • Chappell, L.H.1    Wastling, J.M.2
  • 15
    • 0033952127 scopus 로고    scopus 로고
    • A survey of genes expressed in the adults of the human hookworm, Necator americanus
    • Daub, J., A. Loukas, D. I. Pritchard, and M. Blaxter. 2000. A survey of genes expressed in the adults of the human hookworm, Necator americanus. Parasitology 120:171-184.
    • (2000) Parasitology , vol.120 , pp. 171-184
    • Daub, J.1    Loukas, A.2    Pritchard, D.I.3    Blaxter, M.4
  • 16
    • 0025825036 scopus 로고
    • Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea
    • Day, K. P., W. F. Gregory, and R. M. Maizels. 1991. Age-specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea. Parasite Immunol. 13:277-290.
    • (1991) Parasite Immunol. , vol.13 , pp. 277-290
    • Day, K.P.1    Gregory, W.F.2    Maizels, R.M.3
  • 17
    • 0029977560 scopus 로고    scopus 로고
    • Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster
    • Dick, T., K. Ray, H. K. Salz, and W. Chia. 1996. Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster. Mol. Cell. Biol. 16:1966-1977.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1966-1977
    • Dick, T.1    Ray, K.2    Salz, H.K.3    Chia, W.4
  • 19
    • 0028273544 scopus 로고
    • Protective immunity linked with a distinct developmental stage of a filarial parasite
    • Eisenbiess, W. F., H. Apfel, and T. F. Meyer. 1994. Protective immunity linked with a distinct developmental stage of a filarial parasite. J. Immunol. 152:735-742.
    • (1994) J. Immunol. , vol.152 , pp. 735-742
    • Eisenbiess, W.F.1    Apfel, H.2    Meyer, T.F.3
  • 20
    • 0028006291 scopus 로고
    • Immunity to onchocerciasis: Identification of a putatively immune population in a hyperendemic area of Ecuador
    • Elson, L. H., R. H. Guderian, E. Araujo, J. E. Bradley, A. Days, and T. B. Nutman. 1994. Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. J. Infect. Dis. 169:588-594.
    • (1994) J. Infect. Dis. , vol.169 , pp. 588-594
    • Elson, L.H.1    Guderian, R.H.2    Araujo, E.3    Bradley, J.E.4    Days, A.5    Nutman, T.B.6
  • 21
    • 0033151540 scopus 로고    scopus 로고
    • Deep within the filarial genome: Progress of the filarial genome project
    • The Filarial Genome Project. 1999. Deep within the filarial genome: progress of the filarial genome project. Parasitol. Today 15:219-231.
    • (1999) Parasitol. Today , vol.15 , pp. 219-231
  • 22
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire, A., S. Xu, M. K. Montgomery, S. A. Kostas, S. E. Driver, and C. C. Mello. 1998. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 23
    • 0029919018 scopus 로고    scopus 로고
    • Molecular cloning of a developmentally regulated protein isolated from excretory-secretory products of larval Dirofilaria immitis
    • Frank, G. R., C. A. Tripp, and R B. Grieve. 1996. Molecular cloning of a developmentally regulated protein isolated from excretory-secretory products of larval Dirofilaria immitis. Mol. Biochem. Parasitol. 75:231-240.
    • (1996) Mol. Biochem. Parasitol. , vol.75 , pp. 231-240
    • Frank, G.R.1    Tripp, C.A.2    Grieve, R.B.3
  • 24
    • 0024615636 scopus 로고
    • Purification of a 44 kilodalton protease which mediates the ecdysis of infective Haemonchus contortus larvae
    • Gamble, H. R., J. P. Purcell, and R. H. Fetterer. 1989. Purification of a 44 kilodalton protease which mediates the ecdysis of infective Haemonchus contortus larvae. Mol. Biochem. Parasitol. 33:49-58.
    • (1989) Mol. Biochem. Parasitol. , vol.33 , pp. 49-58
    • Gamble, H.R.1    Purcell, J.P.2    Fetterer, R.H.3
  • 25
    • 0030741671 scopus 로고    scopus 로고
    • Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi
    • Gregory, W. F., M. L. Blaxter, and R. M. Maizels. 1997. Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi. Mol. Biochem. Parasitol. 87:85-95.
    • (1997) Mol. Biochem. Parasitol. , vol.87 , pp. 85-95
    • Gregory, W.F.1    Blaxter, M.L.2    Maizels, R.M.3
  • 26
    • 0030876166 scopus 로고    scopus 로고
    • A filarial cysteine protease inhibitor down-regulates T cell proliferation and enhances interleukin-10 production
    • Hartmann, S., B. Kyewski, B. Sonnenburg, and R. Lucius. 1997. A filarial cysteine protease inhibitor down-regulates T cell proliferation and enhances interleukin-10 production. Eur. J. Immunol. 27:2253-2260.
    • (1997) Eur. J. Immunol. , vol.27 , pp. 2253-2260
    • Hartmann, S.1    Kyewski, B.2    Sonnenburg, B.3    Lucius, R.4
  • 27
    • 0029989299 scopus 로고    scopus 로고
    • Cloning and characterization of Ancylostoma-secreted protein. a novel protein associated with the transition to parasitism by infective hookworm larvae
    • Hawdon, J. M., B. F. Jones, D. R. Hoffman, and P. J. Hotez. 1996. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. J. Biol. Chem. 271:6672-6678.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6672-6678
    • Hawdon, J.M.1    Jones, B.F.2    Hoffman, D.R.3    Hotez, P.J.4
  • 28
    • 0032934497 scopus 로고    scopus 로고
    • Ancylostoma secreted protein 2: Cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum
    • Hawdon, J. M., S. Narasimhan, and P. J. Hotez. 1999. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Mol. Biochem. Parasitol. 99:149-165.
    • (1999) Mol. Biochem. Parasitol. , vol.99 , pp. 149-165
    • Hawdon, J.M.1    Narasimhan, S.2    Hotez, P.J.3
  • 29
    • 0029557842 scopus 로고
    • Protein import into the nucleus: An integrated view
    • Hicks, G. R., and N. V. Raikhel. 1995. Protein import into the nucleus: an integrated view. Annu. Rev. Cell. Dev. Biol. 11:155-188.
    • (1995) Annu. Rev. Cell. Dev. Biol. , vol.11 , pp. 155-188
    • Hicks, G.R.1    Raikhel, N.V.2
  • 30
    • 0029860140 scopus 로고    scopus 로고
    • Molecular identification of a Schistosoma mansoni tegumental protein with similarity to cytoplasmic dynein light chains
    • Hoffmann, K. F., and M. Strand. 1996. Molecular identification of a Schistosoma mansoni tegumental protein with similarity to cytoplasmic dynein light chains. J. Biol. Chem. 271:26117-26123.
    • (1996) J. Biol. Chem. , vol.271 , pp. 26117-26123
    • Hoffmann, K.F.1    Strand, M.2
  • 31
    • 0027289146 scopus 로고
    • Brugia pahangi: Identification and characterization of an aminopeptidase associated with larval molting
    • Hong, X., J. Bouvier, M. M. Wong, G. Y. Yamagata, and J. H. McKerrow. 1993. Brugia pahangi: identification and characterization of an aminopeptidase associated with larval molting. Exp. Parasitol. 76:127-133.
    • (1993) Exp. Parasitol. , vol.76 , pp. 127-133
    • Hong, X.1    Bouvier, J.2    Wong, M.M.3    Yamagata, G.Y.4    McKerrow, J.H.5
  • 32
    • 0031044002 scopus 로고    scopus 로고
    • Identification of larval-stage-specific antigens on Onchocerca volvulus uniquely recognized by putative immune sera from humans and vaccination sera from animal models
    • Irvine, M., E. H. Johnson, and S. Lustigman. 1997. Identification of larval-stage-specific antigens on Onchocerca volvulus uniquely recognized by putative immune sera from humans and vaccination sera from animal models. Ann. Trop. Med. Parasitol. 91:67-77.
    • (1997) Ann. Trop. Med. Parasitol. , vol.91 , pp. 67-77
    • Irvine, M.1    Johnson, E.H.2    Lustigman, S.3
  • 33
    • 0028108258 scopus 로고
    • Identification and characterization of an Onchocerca volvulus cDNA clone encoding a highly immunogenic calponin-like protein
    • Irvine, M., T. Huima, A. M. Prince, and S. Lustigman. 1994. Identification and characterization of an Onchocerca volvulus cDNA clone encoding a highly immunogenic calponin-like protein. Mol. Biochem. Parasitol. 65:135-146.
    • (1994) Mol. Biochem. Parasitol. , vol.65 , pp. 135-146
    • Irvine, M.1    Huima, T.2    Prince, A.M.3    Lustigman, S.4
  • 34
    • 0030049515 scopus 로고    scopus 로고
    • Characterization of a secreted antigen of Onchocerca volvulus with host-protective potential
    • Jenkins, R. E., M. J. Taylor, N. Gilvary, and A. E. Bianco. 1996. Characterization of a secreted antigen of Onchocerca volvulus with host-protective potential. Parasite Immunol. 18:29-42.
    • (1996) Parasite Immunol. , vol.18 , pp. 29-42
    • Jenkins, R.E.1    Taylor, M.J.2    Gilvary, N.3    Bianco, A.E.4
  • 35
    • 0032560461 scopus 로고    scopus 로고
    • Tropomyosin implicated in host protective responses to microfilariae in onchocerciasis
    • Jenkins, R. E., M. J. Taylor, N. J. Gilvary, and A. E. Bianco. 1998. Tropomyosin implicated in host protective responses to microfilariae in onchocerciasis. Proc. Natl. Acad. Sci. USA 95:7550-7555.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7550-7555
    • Jenkins, R.E.1    Taylor, M.J.2    Gilvary, N.J.3    Bianco, A.E.4
  • 36
    • 0029098820 scopus 로고
    • Onchocerca volvulus: A comparative study of in vitro neutrophil killing of microfilariae and humoral responses in infected and endemic normals
    • Johnson, E. H., S. Lustigman, P. H. Kass, M. Irvine, J. Browne, and A. M. Prince. 1995. Onchocerca volvulus: a comparative study of in vitro neutrophil killing of microfilariae and humoral responses in infected and endemic normals. Exp. Parasitol. 81:9-19.
    • (1995) Exp. Parasitol. , vol.81 , pp. 9-19
    • Johnson, E.H.1    Lustigman, S.2    Kass, P.H.3    Irvine, M.4    Browne, J.5    Prince, A.M.6
  • 38
    • 0029898363 scopus 로고    scopus 로고
    • Temporal reiteration of a precise gene expression pattern during nematode development
    • Johnstone, I. L., and J. D. Barry. 1996. Temporal reiteration of a precise gene expression pattern during nematode development. EMBO J. 15:3633-3639.
    • (1996) EMBO J. , vol.15 , pp. 3633-3639
    • Johnstone, I.L.1    Barry, J.D.2
  • 39
    • 0032582728 scopus 로고    scopus 로고
    • Characterization of an Onchocerca volvulus L3-specific larval antigen, Ov-ALT-1
    • Joseph, G. T., T. Huima, and S. Lustigman. 1998. Characterization of an Onchocerca volvulus L3-specific larval antigen, Ov-ALT-1. Mol. Biochem. Parasitol. 96:177-183.
    • (1998) Mol. Biochem. Parasitol. , vol.96 , pp. 177-183
    • Joseph, G.T.1    Huima, T.2    Lustigman, S.3
  • 40
    • 0033953975 scopus 로고    scopus 로고
    • A novel developmentally regulated galectin of Onchocerca volvulus
    • Joseph, G. T., T. Huima, A. Klion, and S. Lustigman. 2000. A novel developmentally regulated galectin of Onchocerca volvulus. Mol. Biochem. Parasitol. 106:187-195.
    • (2000) Mol. Biochem. Parasitol. , vol.106 , pp. 187-195
    • Joseph, G.T.1    Huima, T.2    Klion, A.3    Lustigman, S.4
  • 41
    • 0028175582 scopus 로고
    • OvGalBP, a filarial antigen with homology to vertebrate galactoside-binding proteins
    • Klion, A. D., and J. E. Donelson. 1994. OvGalBP, a filarial antigen with homology to vertebrate galactoside-binding proteins. Mol. Biochem. Parasitol. 65:305-315.
    • (1994) Mol. Biochem. Parasitol. , vol.65 , pp. 305-315
    • Klion, A.D.1    Donelson, J.E.2
  • 43
    • 0028909014 scopus 로고
    • Steroid/thyroid hormone receptor genes in Caenorhabditis elegans
    • Kostrouch, Z., M. Kostrouchova, and J. E. Rall. 1995. Steroid/thyroid hormone receptor genes in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 92:156-159.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 156-159
    • Kostrouch, Z.1    Kostrouchova, M.2    Rall, J.E.3
  • 44
    • 0031832801 scopus 로고    scopus 로고
    • CHR3: A Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting
    • Kostrouchova, M., M. Krause, Z. Kostrouch, and J. E. Rall. 1998. CHR3: a Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting. Development 125:1617-1626.
    • (1998) Development , vol.125 , pp. 1617-1626
    • Kostrouchova, M.1    Krause, M.2    Kostrouch, Z.3    Rall, J.E.4
  • 45
  • 46
    • 0026209699 scopus 로고
    • Acanthocheilonema viteae: Vaccination of jirds with irradiation-attenuated stage-3 larvae and with exported larval antigens
    • Lucius, R., G. Textor, A. Kern, and C. Kirsten. 1991. Acanthocheilonema viteae: vaccination of jirds with irradiation-attenuated stage-3 larvae and with exported larval antigens. Exp. Parasitol. 73:184-196.
    • (1991) Exp. Parasitol. , vol.73 , pp. 184-196
    • Lucius, R.1    Textor, G.2    Kern, A.3    Kirsten, C.4
  • 47
    • 0026804645 scopus 로고
    • Molecular cloning and characterization of onchocystatin, a cysteine proteinase inhibitor of Onchocerca volvulus
    • Lustigman, S., B. Brotman, T. Huima, A. M. Prince, and J. H. McKerrow. 1992. Molecular cloning and characterization of onchocystatin, a cysteine proteinase inhibitor of Onchocerca volvulus. J. Biol. Chem. 267:17339-17346.
    • (1992) . J. Biol. Chem. , vol.267 , pp. 17339-17346
    • Lustigman, S.1    Brotman, B.2    Huima, T.3    Prince, A.M.4    McKerrow, J.H.5
  • 49
    • 0029973555 scopus 로고    scopus 로고
    • Cloning of a cysteine proteinase required for the molting at Onchocerca volvulus third-stage larvae
    • Lustigman, S., J. H. McKerrow, K. Shah, L. Jing, H. Huima, M. Hough, and B. Brotman. 1996. Cloning of a cysteine proteinase required for the molting at Onchocerca volvulus third-stage larvae. J. Biol. Chem. 271:30181-30189.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30181-30189
    • Lustigman, S.1    McKerrow, J.H.2    Shah, K.3    Jing, L.4    Huima, H.5    Hough, M.6    Brotman, B.7
  • 51
    • 0024997232 scopus 로고
    • Primary structure of the major pepsin inhibitor from the intestinal parasitic nematode Ascaris suum
    • Martzen, M. R., B. A. McMullen, N. E. Smith, K. Fujikawa, and R. J. Peanasky. 1990. Primary structure of the major pepsin inhibitor from the intestinal parasitic nematode Ascaris suum. Biochemistry 29:7366-7372.
    • (1990) Biochemistry , vol.29 , pp. 7366-7372
    • Martzen, M.R.1    McMullen, B.A.2    Smith, N.E.3    Fujikawa, K.4    Peanasky, R.J.5
  • 52
    • 0027440945 scopus 로고
    • Nuclear hormone receptors as targets for new drug discovery
    • New York
    • McDonnell, D. P., E. Vegeto, and M. A. Gleeson. 1993. Nuclear hormone receptors as targets for new drug discovery. Bio/Technology (New York) 11:1256-1261.
    • (1993) Bio/Technology , vol.11 , pp. 1256-1261
    • McDonnell, D.P.1    Vegeto, E.2    Gleeson, M.A.3
  • 54
    • 0032972509 scopus 로고    scopus 로고
    • PSORT: A program for detecting sorting signals in proteins and predicting their subcellular localization
    • Nakai, K., and P. Horton. 1999. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. Trends Biochem. Sci. 24:34-36.
    • (1999) Trends Biochem. Sci. , vol.24 , pp. 34-36
    • Nakai, K.1    Horton, P.2
  • 55
    • 0032808666 scopus 로고    scopus 로고
    • Expression and characterization of elastase inhibitors from the ascarid nematodes Anisakis simplex and Ascaris suum
    • Nguyen, T. T., M. A. Qasim, S. Morris, C. C. Lu, D. Hill, M. Laskowski, Jr., and J. A. Sakanari. 1999. Expression and characterization of elastase inhibitors from the ascarid nematodes Anisakis simplex and Ascaris suum. Mol. Biochem. Parasitol. 102:79-89.
    • (1999) Mol. Biochem. Parasitol. , vol.102 , pp. 79-89
    • Nguyen, T.T.1    Qasim, M.A.2    Morris, S.3    Lu, C.C.4    Hill, D.5    Laskowski M., Jr.6    Sakanari, J.A.7
  • 56
    • 0029563562 scopus 로고
    • Molecular cloning and characterization of the filarial LIM domain proteins AvL3-1 and OL3-1
    • Oberlander, U., R. Adam, K. Berg, F. Seeber, and R. Lucius. 1995. Molecular cloning and characterization of the filarial LIM domain proteins AvL3-1 and OL3-1. Exp. Parasitol. 81:592-599.
    • (1995) Exp. Parasitol. , vol.81 , pp. 592-599
    • Oberlander, U.1    Adam, R.2    Berg, K.3    Seeber, F.4    Lucius, R.5
  • 57
    • 0029114309 scopus 로고
    • Molecular characterization of a cyclosporin A-insensitive cyclophilin from the parasitic nematode Brugia malayi
    • Page, A. P., D. Landry, G. G. Wilson, and C. K. Carlow. 1995. Molecular characterization of a cyclosporin A-insensitive cyclophilin from the parasitic nematode Brugia malayi. Biochemistry 34:11545-11550.
    • (1995) Biochemistry , vol.34 , pp. 11545-11550
    • Page, A.P.1    Landry, D.2    Wilson, G.G.3    Carlow, C.K.4
  • 58
    • 0032531371 scopus 로고    scopus 로고
    • A divergent multi-domain cyclophilin is highly conserved between parasitic and free-living nematode species and is important in larval muscle development
    • Page, A. P., and A. D. Winter. 1998. A divergent multi-domain cyclophilin is highly conserved between parasitic and free-living nematode species and is important in larval muscle development. Mol. Biochem. Parasitol. 95:215-227.
    • (1998) Mol. Biochem. Parasitol. , vol.95 , pp. 215-227
    • Page, A.P.1    Winter, A.D.2
  • 59
    • 0033574727 scopus 로고    scopus 로고
    • A highly conserved nematode protein folding operon in Caenorhabditis elegans and Caenorhabditis briggsae
    • Page, A. P. 1999. A highly conserved nematode protein folding operon in Caenorhabditis elegans and Caenorhabditis briggsae. Gene 230:267-275.
    • (1999) Gene , vol.230 , pp. 267-275
    • Page, A.P.1
  • 61
    • 0345411359 scopus 로고    scopus 로고
    • Acanthocheilonema viteae: Characterization of a molt-associated excretory/secretory 18-kDa protein
    • Pogonka, T., U. Oberlander, T. Marti, and R. Lucius. 1999. Acanthocheilonema viteae: characterization of a molt-associated excretory/secretory 18-kDa protein. Exp. Parasitol. 93:73-81.
    • (1999) Exp. Parasitol. , vol.93 , pp. 73-81
    • Pogonka, T.1    Oberlander, U.2    Marti, T.3    Lucius, R.4
  • 62
    • 0026862585 scopus 로고
    • Onchocerca volvulus: Immunization of chimpanzees with X-irradiated third-stage (L3) larvae
    • Prince, A. M., B. Brotman, E. H. Johnson, A. Smith, D. Pascual, and S. Lustigman. 1992. Onchocerca volvulus: immunization of chimpanzees with X-irradiated third-stage (L3) larvae. Exp. Parasitol. 74:239-250.
    • (1992) Exp. Parasitol. , vol.74 , pp. 239-250
    • Prince, A.M.1    Brotman, B.2    Johnson, E.H.3    Smith, A.4    Pascual, D.5    Lustigman, S.6
  • 64
    • 0026914848 scopus 로고
    • Dirofilaria immitis: Proteases produced by third- And fourth-stage larvae
    • Richer, J. K., J. A. Sakanari, G. R. Frank, and R. B. Grieve. 1992. Dirofilaria immitis: proteases produced by third- and fourth-stage larvae. Exp. Parasitol. 75:213-222.
    • (1992) Exp. Parasitol. , vol.75 , pp. 213-222
    • Richer, J.K.1    Sakanari, J.A.2    Frank, G.R.3    Grieve, R.B.4
  • 65
    • 0026078249 scopus 로고
    • Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
    • Robbins, J., S. M. Dilworth, R. A. Laskey, and C. Dingwall. 1991. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 64:615-623.
    • (1991) Cell , vol.64 , pp. 615-623
    • Robbins, J.1    Dilworth, S.M.2    Laskey, R.A.3    Dingwall, C.4
  • 67
    • 0030517172 scopus 로고    scopus 로고
    • Pharmacology of anthelmintic resistance
    • Sangster, N. 1996. Pharmacology of anthelmintic resistance. Parasitology 113:S201-S216.
    • (1996) Parasitology , vol.113
    • Sangster, N.1
  • 68
    • 0030058914 scopus 로고    scopus 로고
    • Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components
    • Savage, C., P. Das, A. L. Finelli, S. R. Townsend, C. Y. Sun, S. E. Baird, and R. W. Padgett. 1996. Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components. Proc. Natl. Acad. Sci. USA 93:790-794.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 790-794
    • Savage, C.1    Das, P.2    Finelli, A.L.3    Townsend, S.R.4    Sun, C.Y.5    Baird, S.E.6    Padgett, R.W.7
  • 69
    • 0031841997 scopus 로고    scopus 로고
    • Resistance of filarial nematode parasites to oxidative stress
    • Selkirk, M. E., V. P. Smith, G. R. Thomas, and K. Gounaris. 1998. Resistance of filarial nematode parasites to oxidative stress. Int. J. Parasitol. 28:1315-1332.
    • (1998) Int. J. Parasitol. , vol.28 , pp. 1315-1332
    • Selkirk, M.E.1    Smith, V.P.2    Thomas, G.R.3    Gounaris, K.4
  • 70
    • 0028827382 scopus 로고
    • Onchocerca volvulus larval antigen, OvB20, induces partial protection in a rodent model of onchocerciasis
    • Taylor, M. J., N. Abdul-Wahab, R. J. Jenkins, and A. E. Bianco. 1995. Onchocerca volvulus larval antigen, OvB20, induces partial protection in a rodent model of onchocerciasis. Infect. Immun. 63:4417-4422.
    • (1995) Infect. Immun. , vol.63 , pp. 4417-4422
    • Taylor, M.J.1    Abdul-Wahab, N.2    Jenkins, R.J.3    Bianco, A.E.4
  • 71
    • 0029906379 scopus 로고    scopus 로고
    • Protective immunity induced by vaccination with Onchocerca volvulus tropomyosin in rodents
    • Taylor, M. J., R. J. Jenkins, and A. E. Bianco. 1996. Protective immunity induced by vaccination with Onchocerca volvulus tropomyosin in rodents. Parasite Immunol. 18:219-225.
    • (1996) Parasite Immunol. , vol.18 , pp. 219-225
    • Taylor, M.J.1    Jenkins, R.J.2    Bianco, A.E.3
  • 72
    • 0028175937 scopus 로고
    • Protective immunity against Onchocerca volvulus and Onchocerca lienalis infective larvae in mice
    • Taylor, M. J., R. P. Van Es, K. Shay, S. G. Folkard, S. Townson, and A. E. Bianco. 1994. Protective immunity against Onchocerca volvulus and Onchocerca lienalis infective larvae in mice. Trop. Med. Parasitol. 45:17-23.
    • (1994) Trop. Med. Parasitol. , vol.45 , pp. 17-23
    • Taylor, M.J.1    Van Es, R.P.2    Shay, K.3    Folkard, S.G.4    Townson, S.5    Bianco, A.E.6
  • 73
    • 0032794702 scopus 로고    scopus 로고
    • Identification of abundantly expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed sequence tag strategy
    • Tetteh, K. K., A. Loukas, C. Tripp, and R. M. Maizels. 1999. Identification of abundantly expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed sequence tag strategy. Infect. Immun. 67:4771-4779.
    • (1999) Infect. Immun. , vol.67 , pp. 4771-4779
    • Tetteh, K.K.1    Loukas, A.2    Tripp, C.3    Maizels, R.M.4
  • 74
    • 0034100620 scopus 로고    scopus 로고
    • Immunity to onchocerciasis: Cells from putatively immune individuals produce enhanced levels of interleukin-5, gamma interferon, and granulocyte-macrophage colony-stimulating factor in response to Onchocerca volvulus larval and male worm antigens
    • Turaga, P. S. D., T. J. Tierney, K. E. Bennett, M. C. McCarthy, S. C. Simonek, P. A. Enyong, D. W. Moukatte, and S. Lustigman. 2000. Immunity to onchocerciasis: cells from putatively immune individuals produce enhanced levels of interleukin-5, gamma interferon, and granulocyte-macrophage colony-stimulating factor in response to Onchocerca volvulus larval and male worm antigens. Infect. Immun. 68:1905-1911.
    • (2000) Infect. Immun. , vol.68 , pp. 1905-1911
    • Turaga, P.S.D.1    Tierney, T.J.2    Bennett, K.E.3    McCarthy, M.C.4    Simonek, S.C.5    Enyong, P.A.6    Moukatte, D.W.7    Lustigman, S.8
  • 75
    • 0021332120 scopus 로고
    • Parasite enzymes as potential targets for antiparasitic chemotherapy
    • Wang, C. C. 1984. Parasite enzymes as potential targets for antiparasitic chemotherapy. J. Med. Chem. 27:1-9.
    • (1984) J. Med. Chem. , vol.27 , pp. 1-9
    • Wang, C.C.1
  • 76
    • 0023911258 scopus 로고
    • Onchocerciasis and immunity in humans: Enhanced T cell responsiveness to parasite antigen in putatively immune individuals
    • Ward, D. J., T. B. Nutman, G. Zea-Flores, C. Portocarrero, A. Lujan, and E. A. Ottesen. 1988. Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals. J. Infect. Dis. 57:536-543.
    • (1988) J. Infect. Dis. , vol.57 , pp. 536-543
    • Ward, D.J.1    Nutman, T.B.2    Zea-Flores, G.3    Portocarrero, C.4    Lujan, A.5    Ottesen, E.A.6
  • 77
    • 0027393937 scopus 로고
    • The filarial antigens Av33/ Ov33-3 show striking similarities to the major pepsin inhibitor from Ascaris suum
    • Willenbucher, J., W. Hofle, and R. Lucius. 1993. The filarial antigens Av33/ Ov33-3 show striking similarities to the major pepsin inhibitor from Ascaris suum. Mol. Biochem. Parasitol. 57:349-351.
    • (1993) Mol. Biochem. Parasitol. , vol.57 , pp. 349-351
    • Willenbucher, J.1    Hofle, W.2    Lucius, R.3
  • 78
    • 0032814768 scopus 로고    scopus 로고
    • Helminth genome analysis: The current status of the filarial and schistosome genome projects. Filarial Genome Project. Schistosome Genome Project
    • Williams, S. A., and D. A. Johnston. 1999. Helminth genome analysis: the current status of the filarial and schistosome genome projects. Filarial Genome Project. Schistosome Genome Project. Parasitology 118:S19-S38.
    • (1999) Parasitology , vol.118
    • Williams, S.A.1    Johnston, D.A.2
  • 79
    • 85176196864 scopus 로고
    • WHO Expert Committee on Onchocerciasis Control. Onchocerciasis and its control
    • World Health Organization, Geneva, Switzerland
    • World Health Organization. 1995. WHO Expert Committee on Onchocerciasis Control. Onchocerciasis and its control. WHO technical report series 852. World Health Organization, Geneva, Switzerland.
    • (1995) WHO Technical Report Series 852
  • 80
    • 0028961048 scopus 로고
    • Characterization of genes encoding members of the nuclear hormone receptor superfamily from Onchocerca volvulus
    • Yates, R. A., R. S. Tuan, K. J. Shepley, and T. R. Unnasch. 1995. Characterization of genes encoding members of the nuclear hormone receptor superfamily from Onchocerca volvulus. Mol. Biochem. Parasitol. 70:19-31.
    • (1995) Mol. Biochem. Parasitol. , vol.70 , pp. 19-31
    • Yates, R.A.1    Tuan, R.S.2    Shepley, K.J.3    Unnasch, T.R.4
  • 81
    • 0028948124 scopus 로고
    • Molecular cloning of a serine proteinase inhibitor from Brugia malayi
    • Yenbutr, P., and A. L. Scott. 1995. Molecular cloning of a serine proteinase inhibitor from Brugia malayi. Infect. Immun. 63:1745-1753.
    • (1995) Infect. Immun. , vol.63 , pp. 1745-1753
    • Yenbutr, P.1    Scott, A.L.2
  • 82
    • 0033567081 scopus 로고    scopus 로고
    • A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases
    • Zang, X., M. Yazdanbakhsh, H. Jiang, M. R. Kanost, and R. M. Maizels. 1999. A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. Blood 94:1418-1428.
    • (1999) Blood , vol.94 , pp. 1418-1428
    • Zang, X.1    Yazdanbakhsh, M.2    Jiang, H.3    Kanost, M.R.4    Maizels, R.M.5
  • 83
    • 0028012086 scopus 로고
    • Polymerase chain reaction-based diagnosis of Onchocerca volvulus infection: Improved detection of patients with onchocerciasis
    • Zimmerman, P. A., R. H. Guderian, E. Aruajo, L. Elson, P. Phadke, J. Kubofcik, and T. B. Nutman. 1994. Polymerase chain reaction-based diagnosis of Onchocerca volvulus infection: improved detection of patients with onchocerciasis. J. Infect. Dis. 169:686-689.
    • (1994) J. Infect. Dis. , vol.169 , pp. 686-689
    • Zimmerman, P.A.1    Guderian, R.H.2    Aruajo, E.3    Elson, L.4    Phadke, P.5    Kubofcik, J.6    Nutman, T.B.7


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