A Pharmacodynamic Analysis of TCDD-Induced Cytochrome P450 Gene Expression in Multiple Tissues: Dose- and Time-Dependent Effects

Toxicology and Applied Pharmacology

Volumn 151, Issue 2, 1998, Pages 294-310

  Santostefano, Michael J ^a,c   Wang, Xiaofeng ^a,b   Richardson, Vicki M ^c   Ross, David G ^c   DeVito, Michael J ^c   Birnbaum, Linda S ^c  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b MGA Software Inc   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; METHOXYRESORUFIN O DEMETHYLASE; METHOXYRESORUFIN-O-DEMETHYLASE; OXIDOREDUCTASE;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; BIOLOGICAL MODEL; DOSE RESPONSE; DRUG EFFECT; FEMALE; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM; RAT; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LIVER; MODELS, BIOLOGICAL; ORGAN SPECIFICITY; OXIDOREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; TETRACHLORODIBENZODIOXIN; TIME FACTORS;

EID: 0032135591     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1998.8466     Document Type: Article

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