EDHF, NO and a prostanoid: Hyperpolarization-dependent and -independent relaxation in guinea-pig arteries

British Journal of Pharmacology

Volumn 130, Issue 3, 2000, Pages 605-618

  Tare, Marianne ^a   Parkington, Helena C ^a   Coleman, H A ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Coronary artery; Endothelium derived hyperpolarizing factor; Hyperpolarization; Mammary artery; Membrane potential; Nitric oxide; Prostacyclin; Relaxation; Vascular smooth muscle

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ACETYLCHOLINE; GLIBENCLAMIDE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTANOID;

ANIMAL TISSUE; ARTERY; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM; FEMALE; GUINEA PIG; HYPERPOLARIZATION; MALE; MAMMARY ARTERY; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; VASODILATATION;

EID: 0034109583     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703332     Document Type: Article

References (41)

1. ARCHER, S.L., HUANG, J.M.C., HAMPL, V., NELSON, D.P., SHULTZ, P.J. & WEIR, E.K. (1994). Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc. Natl. Acad. Sci. U.S.A., 91, 7583-7587.
2. BAUERSACHS, J., POPP, R., HECKER, M., SAUER, E., FLEMING, I. & BUSSE, R. (1996). Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation, 94, 3341-3347.
3. BÉNY, J.-L. (1997). Electrical coupling between smooth muscle cells and endothelial cells in pig coronary arteries. Pflügers Arch., 433, 364-367.
4. BOLOTINA, V.M., NAJIBI, S., PALACINO, J.J., PAGANO, P.J. & COHEN, R.A. (1994). Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature, 368, 850-853.
5. +-channel blockers on ACh-induced hyperpolarization and relaxation in mesenteric arteries. Am. J. Physiol., 272, H2306-H2312.
6. CHEUNG, D.W., CHEN, G., MACKAY, M.J. & BURNETTE, E. (1999). Regulation of vascular tone by endothelium-derived hyperpolarizing factor. Clin. Exp. Pharmacol. Physiol., 26, 172-175.
7. COHEN, R.A., PLANE, F., NAJIBI, S., JUK, I., MALINSKI, T. & GARLAND, C.J. (1997). Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit coronary artery. Proc. Natl. Acad. Sci. U.S.A., 94, 4193-4198.
8. CORRIU, C., FÉLÉTOU, M., CANET, E. & VANHOUTTE, P.M. (1996). Endothelium-derived factors and hyperpolarization of the carotid artery of the guinea-pig. Br. J. Pharmacol., 119, 959-964.
9. DONG, H., WALDRON, G.J., COLE, W.C. & TRIGGLE, C.R. (1998). Roles of calcium-activated and voltage-gated delayed rectifier potassium channels in endothelium-dependent vasorelaxation of the rabbit middle cerebral artery. Br. J. Pharmacol., 123, 821-832.
10. EDWARDS, G. & WESTON, A.H. (1998). Endothelium-derived hyperpolarizing factor - a critical appraisal. Prog. Drug Res., 50, 108-133.
11. + is an endothelium-derived hyperpolarizing factor in rat arteries. Nature, 396, 269-272.
12. FISSLTHALER, B., POPP, R., KISS, L., POTENTE, M., HARDER, D.R., FLEMING, I. & BUSSE, R. (1999). Cytochrome P450 2C is an EDHF synthase in coronary arteries. Nature, 401, 493-497.
13. FUJII, K., TOMINAGA, M., OHMORI, S., KOBAYASHI, K., KOGA, T., TAKATA, Y. & FUJISHIMA, M. (1992). Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats. Circ. Res., 70, 660-669.
14. FUKAO, M., HATTORI, Y., KANNO, M., SAKUMA, I. & KITABATAKE, A. (1997). Alterations in endothelium-dependent hyperpolarization and relaxation in mesenteric arteries from streptozotocin-induced diabetic rats. Br. J. Pharmacol., 121, 1383-1391.
15. GARLAND, C.J. & MCPHERSON, G.A. (1992). Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery. Br. J. Pharmacol., 105, 429-435.
16. GARLAND, C.J., PLANE, F., KEMP, B. & COCKS, T. (1995). Endothelium-derived hyperpolarizing factor. Trends Pharmacol. Sci., 16, 23-30.
17. GRIFFITH, T.M. & TAYLOR, H.J. (1999). Cyclic AMP mediates EDHF-type relaxations of rabbit jugular vein. Biochem. Biophys. Res. Commun., 263, 52-57.
18. HAMMARSTRÖM, A.K.M., PARKINGTON, H.C., TARE, M. & COLEMAN, H.A. (1999). Endothelium-dependent hyperpolarization in resting and depolarized mammary and coronary arteries of guinea-pigs. Br. J. Pharmacol., 126, 421-428.
19. HOLZMANN, S., KUKOVETZ, W.R. & SCHMIDT, K. (1980). Mode of action of coronary arterial relaxation by prostacyclin. J. Cyc. Nucl. Res., 6, 451-460.
20. IGNARRO, L.J., BURKE, T.M., WOOD, K.S., WOLIN, M.S. & KADOWITZ, P.J. (1984). Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery. J. Pharmacol. Exp. Ther., 228, 682-690.
21. G-nitro-L-arginine in pulmonary hypertension. Br. J. Pharmacol., 116, 2457-2467.
22. KILPATRICK, E.V. & COCKS, T.M. (1994). Evidence for differential roles of nitric oxide (NO) and hyperpolarization in endothelium-dependent relaxation of pig isolated coronary artery. Br. J. Pharmacol., 112, 557-565.
23. + channels in cultured vascular smooth muscle cells. Circ. Res., 74, 471-476.
24. MCCULLOCH, A.I., BOTTRILL, F.E., RANDALL, M.D. & HILEY, C.R. (1997). Characterization and modulation of EDHF-mediated relaxations in the rat isolated superior mesenteric arterial bed. Br. J. Pharmacol., 120, 1431-1438.
25. MULVANY, M.J. & HALPERN, W. (1977). Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats. Circ. Res., 41, 19-26.
26. + channels mediate an endothelium-dependent hyperpolarization in rabbit mesenteric arteries. J. Physiol., 489, 723-734.
27. G-nitro-L-arginine in rats. Am. J. Physiol., 263, H1090-H1094.
28. NISHIYAMA, M., HASHITANI, H., FUKUTA, H., YAMAMOTO, Y. & SUZUKI, H. (1998). Potassium channels activated in the endothelium-dependent hyperpolarization in guinea-pig coronary artery. J. Physiol., 510, 455-465.
29. PARKINGTON, H.C., TARE, M., TONTA, M.A. & COLEMAN, H.A. (1993). Stretch revealed three components in the hyperpolarization of guinea-pig coronary artery in response to acetylcholine. J. Physiol., 465, 459-476.
30. PARKINGTON, H.C., TONTA, M.A., COLEMAN, H.A. & TARE, M. (1995). Role of membrane potential in endothelium-dependent relaxation of guinea-pig coronary arterial smooth muscle. J. Physiol., 484, 469-480.
31. PLANE, F., PEARSON, T. & GARLAND, C.J. (1995). Multiple pathways underlying endothelium-dependent relaxation in the rabbit isolated femoral artery. Br. J. Pharmacol., 115, 31-38.
32. PLANE, F., WILEY, K.E., JEREMY, J.Y., COHEN, R.A. & GARLAND, C.J. (1998). Evidence that different mechanisms underlie smooth muscle relaxation to nitric oxide and nitric oxide donors in the rabbit isolated carotid artery. Br. J. Pharmacol., 123, 1351-1358.
33. + currents in rabbit arterial smooth muscle via protein kinase A. J. Physiol., 475, 9-13.
34. RAPOPORT, R.M. & MURAD, F. (1983). Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP. Circ. Res., 52, 352-357.
35. ca- channel activation by cAMP-dependent protein kinase. Am. J. Physiol., 272, H1147-H1156.
36. SHIMOKAWA, H., YASUTAKE, H., FUJII, K., OWADA, M.K., NAKAIKE, R., FUKUMOTO, Y., TAKAYANAGI, T., NAGAO, T., EGASHIRA, K., FUJISHIMA, M. & TAKESHITA, A. (1996). The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J. Cardiovasc. Pharmacol., 28, 703-711.
37. YAJIMA, K., NISHIYAMA, M., YAMAMOTO, Y. & SUZUKI, H. (1999). Inhibition of endothelium-dependent hyperpolarization by endothelial prostanoids in guinea-pig coronary artery. Br. J. Pharmacol., 126, 1-10.
38. YAMANAKA, A., ISHIKAWA, T. & GOTO, K. (1998). Characterization of endothelium-dependent relaxation independent of NO and prostaglandins in guinea-pig coronary artery. J. Pharmacol. Exp. Ther., 285, 480-489.
39. ZYGMUNT, P.M., PLANE, F., PAULSSON, M., GARLAND, C.J. & HÖGESTÄTT, E.D. (1998). Interactions between endothelium-derived relaxing factors in the rat hepatic artery: focus on regulation of EDHF. Br. J. Pharmacol., 124, 992-1000.
40. ZYGMUNT, P.M., RYMAN, T. & HÖGESTÄTT, E.D. (1995). Regional differences in endothelium-dependent relaxation in the rat-contribution of nitric oxide and nitric oxide-independent mechanisms. In: Zygmunt, P.M.: Ph.D. thesis. Endothelium-dependent hyperpolarization and relaxation of vascular smooth muscle. Lund University: Sweden.
41. ZYGMUNT, P.M., WALDECK, K. & HÖGESTÄTT, E.D. (1994). The endothelium mediates a nitric oxide-independent hyperpolarization and relaxation in the rat hepatic artery. Acta Physiol. Scand., 152, 375-384.