Transcriptional regulation of the cellular retinoic acid binding protein I gene in F9 teratocarcinoma cells

Cell Growth and Differentiation

Volumn 11, Issue 2, 2000, Pages 71-82

  Means, Anna L ^a,b   Thompson, James R ^a   Gudas, Lorraine J ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MESSENGER RNA; RETINOIC ACID; RETINOIC ACID BINDING PROTEIN;

ANIMAL CELL; ARTICLE; CARCINOMA CELL; CELL DIFFERENTIATION; CONTROLLED STUDY; DNA SEQUENCE; ENHANCER REGION; GENE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RNA ANALYSIS; TERATOCARCINOMA; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL NUCLEUS; DNA FOOTPRINTING; ENHANCER ELEMENTS (GENETICS); FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; MICE; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, RETINOIC ACID; RNA, MESSENGER; RNA, NEOPLASM; TERATOCARCINOMA; TRANSCRIPTION, GENETIC; TRANSFECTION; TRETINOIN; TUMOR CELLS, CULTURED;

ANIMALIA; MURINAE;

EID: 0034108269     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (83)

1. Gudas, L. J., Sporn, M. B., and Roberts, A. B. Cellular biology and biochemistry of the retinoids. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (ed.), The Retinoids: Biology, Chemistry, and Medicine, pp. 443-520. New York: Raven Press, 1994.
2. Hofmann, C., and Eichele, G. Retinoids in development. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (ed.), The Retinoids: Biology, Chemistry, and Medicine, pp. 387-442. New York: Raven Press, 1994.
3. Morriss-Kay, G. M., and Sokolova, N. Embryonic development and pattern formation. FASEB J., 10: 961-968, 1996.
4. Shenefelt, R. Morphogenesis of malformations in hamsters caused by retinoic acid: relation to dose and stage at treatment. Teratology, 5: 103-118, 1972.
5. Morriss, G. M. Morphogenesis of the malformations induced in rat embryos by maternal hypervitaminosis A. J. Anat., 113: 241-250, 1972.
6. Lammer, E. J., Chen, D. T., Hoar, R. M., Agnish, N. D., Benke, P. J., Braun, J. T., Curry, C. J., Fernhoff, P. M., Grix, A. W., Jr., Lott, I. T., Richard, J. M., and Sun, S. C. Retinoic acid embryopathy. N. Engl. J. Med., 313: 837-841, 1985.
7. Means, A. L., and Gudas, L. J. The roles of retinoids in vertebrate development. Annu. Rev. Biochem., 64: 210-233, 1995.
8. Napoli, J. L. Retinoic acid biosynthesis and metabolism. FASEB J., 10: 993-1001, 1996.
9. Napoli, J. L., Boerman, M. H., Chai, X., Zhai, Y., and Fiorella, P. D. Enzymes and binding proteins affecting retinoic acid concentrations. J. Steroid Biochem. Mol. Biol., 53: 497-502, 1995.
10. De Coster, R., Wouters, W., and Bruynseels, J. P450-dependent enzymes as targets for prostate cancer therapy. J. Steroid Biochem. Mol. Biol., 56: 133-143, 1996.
11. Duester, G. Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis. Biochemistry, 35: 12221-12227, 1996.
12. Hendriks, H. F. Retinoid (vitamin A) metabolism. Eur. J. Clin. Nutr., 50: S2-S6, 1996.
13. Zhao, D., McCaffery, P., Ivins, K. J., Neve, R. L., Hogan, P., Chin, W. W., and Drager, U. C. Molecular identification of a major retinoic-acid-synthesizing enzyme, a retinaldehyde-specific dehydrogenase. Eur. J. Biochem., 240: 15-22, 1996.
14. White, J. A., Guo, Y-D., Baetz, K., Beckett-Jones, B., Bonasoro, J., Hsu, K. E., Dilworth, F. J., Jones, G., and Petkovich, M. Identification of the retinoic acid-inducible all-trans-retinoic 4-hydroxylase. J. Biol. Chem., 271: 29922-29927, 1996.
15. Fujii, H., Sato, T., Kaneko, S., Gotoh, O., Fujii-Kuriyama, Y., Osawa, K., Kato, S., and Hamada, H. Metabolic motivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos. EMBO J., 16: 4163-4173, 1997.
16. Ray, W. J., Bain, G., Yao, M., and Gottlieb, D. I. CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family. J. Biol. Chem., 272: 18702-18708, 1997.
17. Mangelsdorf, D. J., Umesono, K., and Evans, R. M. The retinoid receptors. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (ed.), The Retinoids: Biology, Chemistry and Medicine, pp. 319-350. New York: Raven Press, 1994.
18. Ong, D. E., Newcomer, M. E., and Chytil, F. Cellular retinoid-binding proteins. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (ed.), The Retinoids: Biology, Chemistry and Medicine, pp. 283-318. New York: Raven Press, 1994.
19. Boylan, J. F., and Gudas, L. J. Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells. J. Cell. Biol., 112: 965-979, 1991.
20. Boylan, J. F., and Gudas, L. J. The level of CRABP-I expression influences the amounts and types of all-frans-retinoic acid metabolites in F9 teratocarcinoma stem cells. J. Biol. Chem., 267: 21486-21491, 1992.
21. Napoli, J. L. Biochemical pathways of retinoid transport, metabolism, and signal transduction. Clin. Immunol. Immunopathol., 80: S52-S62, 1996.
22. Dekker, E-J., Vaessen, M-J., van den Berg, C., Timmermans, A., Godsave, S., Holling, T., Nieukwoop, P., van Kessel, A. G., and Durston, A. Overexpression of a cellular retinoic acid binding protein (xCRABP) causes anteroposterior defects in developing Xenopus embryos. Development (Camb.), 120: 973-985, 1994.
23. Lampron, C., Rochette-Egly, C., Gorry, P., Dolle, P., Mark, M., Lufkin, T., LeMeur, M., and Chambon, P. Mice deficient in cellular retinoic acid binding protein II (CRABPII) or in both CRABPI and CRABPII are essentially normal. Development (Camb.), 121: 539-548, 1995.
24. Gustafson, A. L., Donovan, M., Annerwall, E., Dencker, L., and Eriksson, U. Nuclear import of cellular retinoic acid-binding protein type I in mouse embryonic cells. Mech. Dev., 58: 27-38, 1996.
25. Bailey, J. S., and Siu, C. H. Purification and partial characterization of a novel binding protein for retinoic acid from neonatal rat. J. Biol. Chem., 263: 9326-9332, 1988.
26. Dollé, P., Ruberte, E., Kastner, P., Petkovich, M., Stoner, C. M., Gudas, L. J., and Chambon, P. Differential expression of genes encoding α, β and γ retinoic acid receptors and CRABP in the developing limbs of the mouse. Nature (Lond.), 342: 702-705, 1989.
27. Ruberte, E., Dollé, P., Chambon, P., and Morriss-Kay, G. Retinoic acid receptors and cellular retinoid binding proteins. II. their differential pattern of transcription during early morphogenesis in mouse embryos. Development (Camb.), 111: 45-60, 1991.
28. Ruberte, E., Friederich, V., Morriss-Kay, G., and Chambon, P. Differential distribution patterns of CRABP I and CRABP II transcripts during mouse embryogenesis. Development (Camb.), 115: 973-987, 1992.
29. Ruberte, E., Friederich, V., Chambon, P., and Morriss-Kay, G. Retinoic acid receptors and cellular retinoid binding proteins. III. Their differential transcript distribution during mouse nervous system development. Development (Camb.), 118: 267-282, 1993.
30. Lyn, S., and Giguere, V. Localization of CRABP-I and CRABP-II mRNA in the early mouse embryo by whole-mount in situ hybridization: implications for teratogenesis and neural development. Dev. Dyn., 199: 280-291, 1994.
31. Leonard, L., Norton, C., Maden, M., and Pizzey, J. A. Anteriorization of CRABP-I expression by retinoic acid in the developing mouse central nervous system and its relationship to teratogenesis. Dev. Biol., 168: 514-528, 1995.
32. Strickland, S., and Mahdavi, V. The induction of differentiation in teratocarcinoma stem cells by retinoic acid. Cell, 15: 393-403, 1978.
33. Stoner, C. M., and Gudas, L. J. Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells. Cancer Res., 49: 1497-1504, 1989.
34. McBurney, M. W., Jones-Villeneuve, E. M., Edwards, M. K., and Anderson, P. J. Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line. Nature (Lond.), 299: 165-167, 1982.
35. Jones-Villeneuve, E. M., McBurney, M. W., Rogers, K. A., and Kalnins, V. I. Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J. Cell. Biol., 94: 253-262, 1982.
36. Jones-Villeneuve, E. M., Rudnicki, M. A., Harris, J. F., and McBurney, M. W. Retinoic acid-induced neural differentiation of embryonal carcinoma cells. Mol. Cell. Biol., 3: 2271-2279, 1983.
37. Wei, L-N., Blaner, W. S., Goodman, D. S., and Nguyen-Huu, M. C. Regulation of the cellular retinoid-binding proteins and their messenger ribonucleic acids during P19 embryonal carcinoma cell differentiation induced by retinoic acid. Mol. Endocrinol., 3: 454-463, 1989.
38. Li, E., Bestor, T. H., and Jaenisch, R. Targeted disruption of the DNA methyltransferase gene results in embryonic lethality. Cell, 69: 915-926, 1992.
39. Means, A. L., and Gudas, L. J. FGF-2, BMP-2, and BMP-4 regulate retinoid binding proteins and receptors in 3T3 cells. Cell Growth Differ., 7: 989-996, 1996.
40. Means, A. L., and Farnham, P. J. Transcription initiation from the dihydrofolate reductase promoter is positioned by HIP1 binding at the initiation site. Mol. Cell. Biol., 10: 653-661, 1990.
41. Wei, L-N., Chen, G-J., Chu, Y-S., Tsao, J-L., and Nguyen-Huu, M. C. A 3 kb sequence from the mouse cellular retinoic-acid-binding protein gene upstream region mediates spatial and temporal lacZ expression in transgenic mouse embryos. Development (Camb.), 112: 847-854, 1991.
42. Fukuda, M., Ikuma, S., Setoyama, C., and Shimada, K. Decrease in the c-myb gene transcript during differentiation of mouse teratocarcinoma stem cells. Biochem. Int., 15: 73-79, 1987.
43. Dony, C., Kessel, M., and Gruss, P. Post-transcriptional control of myc and p53 expression during differentiation of the embryonal carcinoma cell line F9. Nature (Lond.), 317: 636-639, 1985.
44. Griep, A. E., and De Luca, H. F. Decreased c-myc expression is an early event in retinoic acid-induced differentiation of F9 teratocarcinoma cells. Proc. Natl. Acad. Sci. USA, 83: 5539-5543, 1986.
45. Dean, M., Levine, R. A., and Campisi, J. c-myc regulation during retinoic acid-induced differentiation of F9 cells is posttranscriptional and associated with growth arrest. Mol. Cell. Biol., 6: 518-524, 1986.
46. Finklestein, R., and Weinberg, R. A. Differential regulation of N-myc and c-myc expression in F9 teratocarcinoma cells. Oncogene Res., 3: 287-292, 1988.
47. Kato, K., Kanamori, A., and Kondoh, H. Rapid and transient decrease of N-myc expression in retinoic acid-induced differentiation of OTF9 teratocarcinoma stem cells. Mol. Cell. Biol., 10: 486-491, 1990.
48. Scholer, H. R., Balling, R., Hatzopoulos, A. K., Suzuki, N., and Gruss, P. Octamer binding proteins confer transcriptional activity in early mouse embryogenesis. EMBO J., 8: 2551-2557, 1989.
49. Lenardo, M. J., Staudt, L., Robbins, P., Kuang, A., Mulligan, R. C., and Baltimore, D. Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. Science (Washington DC), 243: 544-546, 1989.
50. Okazawa, H., Okamoto, K., Ishino, F., Ishino-Kaneko, T., Takeda, S., Toyoda, Y., Muramatsu, M., and Hamada, H. The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. EMBO J., 10: 2997-3005, 1991.
51. Yuan, H., Corbi, N., Basilico, C., and Dailey, L. Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev., 9: 2635-2645, 1995.
52. Xin, J. H., Cowie, A., Lachance, P., and Hassell, J. A. Molecular cloning of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells. Genes Dev., 6: 481-496, 1992.
53. Chandrasekaran, K., Mora, P. T., Nagarajan, L., and Anderson, W. B. The amount of a specific cellular protein (p53) is a correlate of differentiation in embryonal carcinoma cells. J. Cell. Physiol., 113: 134-140, 1982.
54. Oren, M., Reich, N. C., and Levine, A. J. Regulation of the cellular p53 tumor antigen in teratocarcinoma cells and their differentiated progeny. Mol. Cell. Biol., 2: 443-449, 1982.
55. Hosler, B. A., La Rosa, G. J., Grippo, J. F., and Gudas, L. J. Expression of REX-1, a gene containing zinc finger motifs, is rapidly reduced by retinoic acid in F9 teratocarcinoma cells. Mol. Cell. Biol., 9: 5623-5629, 1989.
56. Ben-Shushan, E., Thompson, J. R., Gudas, L. J., and Bergman, Y. Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via oct-3/4 and oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site. Mol. Cell. Biol., 18: 1866-1878, 1998.
57. Hosler, B. A., Rogers, M. B., Kozak, C. A., and Gudas, L. J. An octamer motif contributes to the expression of the retinoic acid-regulated zinc finger gene Rex-1 (Zpf-42) in F9 teratocarcinoma cells. Mol. Cell. Biol., 13: 2919-2928, 1993.
58. Bastian, H., and Gruss, P. A murine even-skipped homologue, Evx 1, is expressed during early embryogenesis and neurogenesis in a biphasic manner. EMBO J., 9: 1839-1852, 1990.
59. Hromas, R., Collins, S. J., Hickstein, D., Raskind, W., Deaven, L. L., O'Hara, P., Hagen, F. S., and Kaushansky, K. A retinoic acid-responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells. J. Biol. Chem., 266: 14183-14187, 1991.
60. Morris, J. F., Hromas, R., and Rauscher, F. J., III. Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1: two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich core. Mol. Cell. Biol., 14: 1786-1795, 1994.
61. Robertson, K. A., Hill, D. P., Kelley, M. R., Tritt, R., Crum, B., Van Epps, S., Srour, E., Rice, S., and Hromas, R. The myeloid zinc finger gene (MZF-1) delays retinoic acid-induced apoptosis and differentiation in myeloid leukemia cells. Leukemia (Baltimore), 12: 690-698, 1998.
62. Hromas, R., Morris, J., Cornetta, K., Berebitsky, D., Davidson, A., Sha, M., Sledge, G., and Rauscher, F. J., III. Aberrant expression of the myeloid zinc finger gene, MZF-1, is oncogenic. Cancer Res., 55: 3610-3614, 1995.
63. Okuda, A., Fukishima, A., Nishimoto, M., Orimo, A., Yamagishi, T., Nabeshima, Y., Kuro, M., Nabeshima, Y., Boon, K., Keaveney, M., Stunnenberg, H. G., and Muramatsu, M. UTFI, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells. EMBO J., 17: 2019-2032, 1998.
64. Means, A. L., and Gudas, L. J. The CRABP I gene contains two separable, redundant regulatory regions active in neural tissues in transgenic mouse embryos. Dev. Dyn., 209: 59-69, 1997.
65. Kleinjan, D. A., Dekker, S., Vaessen, M. J., and Grosveld, F. Regulation of the CRABP-I gene during mouse embryogenesis. Mech. Dev., 67: 157-169, 1997.
66. Wei, L-N., and Chang, L. Promoter and upstream regulatory activities of the mouse cellular retinoic acid-binding protein-I gene. J. Biol. Chem., 271: 5073-5078, 1996.
67. Wei, L-N., Lee, C. H., and Chang, L. Retinoic acid induction of mouse cellular retinoic acid-binding protein-I gene expression is enhanced by sphinganine. Mol. Cell. Endocrinol., 111: 207-211, 1995.
68. Chang, L., and Wei, L-N. Characterization of a negative response DNA element in the upstream region of the cellular retinoic acid-binding protein-I gene of the mouse. J. Biol. Chem., 272: 10144-10150, 1997.
69. Chinpaisal, C., Chang, L., Hu, X., Lee, C. H., Wen, W. N., and Wei, L-N. The orphan receptor TR2 suppresses a DR4 hormone response element of the mouse CRABP-I gene promoter. Biochemistry, 36: 14088-14095, 1997.
70. Wei, L-N., Tsao, J-L., Chu, Y-S., Jeannotte, L, and Nguyen-Huu, M. C. Molecular cloning and transcriptional mapping of the mouse cellular retinoic acid-binding protein gene. DNA Cell Biol., 9: 471-478, 1990.
71. Wei, L-N., Lee, C. H., Filipcik, P., and Chang, L. Regulation of the mouse cellular retinoic acid-binding protein-I gene by thyroid hormone and retinoids in transgenic mouse embryos and P19 carcinomas. J. Endocrinol., 155: 35-46, 1997.
72. Chirgwin, J. M., Przybyla, R. J., MacDonald, R. J., and Rutter, W. J. Isolation of biologically active ribonucleic acid from sources enriched in ribonucleases. Biochemistry, 18: 5294-5299, 1979.
73. Glanville, N., Durnam, D. M., and Palmitter, R. D. Structure of mouse metallothionein-I gene and its mRNA. Nature (Lond.), 292: 267-269, 1982.
74. Hanauer, A., and Mandel, J. L. The glyceraldehyde 3 phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse. EMBO J., 3: 2627-2633, 1984.
75. Luckow, B., and Schutz, G. CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucl. Acids Res., 15: 5490, 1987.
76. Clark, A. R., Boam, D. S. W., and Doeherty, K. A new series of CAT expression vectors. Nucl. Acids Res., 17: 10130, 1989.
77. Vasios, G. W., Gold, J. D., Petkovich, M., Chambon, P., and Gudas, L. J. A retinoic acid-responsive element is present in the 5′ flanking region of the laminin B1 gene. Proc. Natl. Acad. Sci. USA, 86: 9099-10003, 1989.
78. LaRosa, G. J., and Gudas, L. J. The early retinoic acid-induced F9 teratocarcinoma stem cell gene ERA-1: alternate splicing creates both a transcript for a homeobox-containing protein and one lacking the homeobox. Mol. Cell. Biol., 8: 3906-3917, 1988.
79. Wang, S-Y., LaRosa, G., and Gudas, L. J. Molecular cloning of gene sequences transcriptionally regulated by retinoic acid and dibutyryl cyclic AMP in cultured mouse teratocarcinoma cells. Dev. Biol., 107: 75-86, 1985.
80. Herbomel, P., Bourachot, B., and Yaniv, M. Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma. Cell, 39: 653-662, 1984.
81. German, C. M., Moffat, L. F., and Howard, B. H. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol., 2: 1044-1051, 1982.
82. Dignam, J. D., Lebovitz, R. M., and Roeder, R. G. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei, Nucleic Acids Res., 11: 1475-1489, 1983.
83. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.