UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells

EMBO Journal

Volumn 17, Issue 7, 1998, Pages 2019-2032

  Okuda, Akihiko ^a   Fukushima, Akiko ^a   Nishimoto, Masazumi ^a   Orimo, Akira ^a   Yamagishi, Toshiyuki ^a   Nabeshima, Yoko ^b   Kuro o, Makoto ^b   Nabeshima, Yo Ichi ^b   Boon, Kathy ^c   Keaveney, Marie ^c,d   Stunnenberg, Hendrik G ^c,e   Muramatsu, Masami ^f  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d HARVARD MEDICAL SCHOOL   (United States)

^e RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^f NONE

Author keywords

ATF 2; E1A like activity; Embryonic stem cells; Transcriptional coactivator

Indexed keywords

TRANSCRIPTION FACTOR; VIRUS PROTEIN;

ADENOVIRUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; EMBRYO; EMBRYO DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; STEM CELL; TISSUE SPECIFICITY;

ACTIVATING TRANSCRIPTION FACTOR 2; ADENOVIRUS E2 PROTEINS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CHO CELLS; CLONING, MOLECULAR; CRICETINAE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; STEM CELLS; TRANS-ACTIVATORS; TRANSCRIPTION FACTOR TFIID; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFII; TUMOR STEM CELLS;

ADENOVIRIDAE; ANIMALIA; MAMMALIA;

EID: 0032055125     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.7.2019     Document Type: Article

References (70)

1. Avantaggiati,M.L., Ogryzko,V., Gardner,K., Giordano,A., Levine,A.S. and Kelly,K. (1997) Recruitment of p300/CBP in p53-dependent signal pathways. Cell, 89, 1175-1184.
2. Bandara,L.R. and La Thangue,N.B. (1991) Adenovirus E1a prevents the retinoblastoma gene product from complexing with a cellular transcription factor. Nature, 351, 494-497.
3. Berkenstam,A., Vivanco Ruiz,M.d.M., Barettino,D., Horikoshi,M. and Stunnenberg,H.G. (1992) Cooperativity in transactivation between retinoic acid receptor and TFIID requires an activity analogous to E1A. Cell, 69, 401-412.
4. Bhattacharya,S., Eckner,R., Grossman,S., Oldread,E., Arany,Z., D'Andrea,A. and Livingston,D.M. (1996) Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α. Nature, 383, 344-347.
5. Brill,S.J. and Sternglanz,R. (1988) Transcription-dependent DNA supercoiling in yeast DNA topoisomerase mutants. Cell, 54, 403-411.
6. Chakravarti,D., LaMorte,V., Nelson,N.C., Nakajima,T., Schulman,I.G., Juguilon,H., Montminy,M. and Evans,R.M. (1996) Role of CBP/p300 in nuclear receptor signalling. Nature, 383, 99-103.
7. Chen,W. and Struhl,K. (1988) Saturation mutagenesis of a yeast HIS3 'TATA element': Genetic evidence for a specific TATA-binding protein. Proc. Natl Acad. Sci. USA, 85, 2691-2695.
8. Cheng,X., Reginato,M.J., Andrews,N.C. and Lazar,M.A. (1997) The transcriptional integrator CREB-binding protein mediates positive cross talk between nuclear hormone receptors and the hematopoietic bZip protein p45/NF-E2. Mol. Cell. Biol., 17, 1407-1416.
9. Chien,C.T., Bartel,P.L., Sternglanz,R. and Fields,S. (1991) The two-hybrid system: A method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl Acad. Sci. USA, 88, 1338-1343.
10. Cohen,C. and Parry,D.A. (1994) α-Helical coiled coils: more facts and better predictions. Science, 263, 488-489.
11. Colberg-Poley,A-M., Voss,S.D., Chowdhury,K. and Gruss,P. (1985) Structural analysis of murine genes containing homeo box sequences and their expression in embryonic carcinoma cells. Nature, 314, 713-718.
12. Collart,M. and Struhl,K. (1994) NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization. Genes Dev., 8, 525-537.
13. Dai,P., Akimaru,H., Tanaka,Y., Hou,D.X., Yasukawa,T., Kanei-ishii,C., Takahashi, T. and Ishii,S. (1996) CBP as a transcriptional coactivator of c-Myb. Genes Dev., 10, 528-540.
14. Dam,H.V., Wilhelm,D., Herr,I., Steffen,A., Herrlich,P. and Angel,P. (1995) ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. EMBO J., 14, 1798-1811.
15. Diamond,M.L., Miner,J.N., Yoshinaga,S.K. and Yamamoto,K.R. (1990) Transcription factor interactions: selectors of positive or negative regulation from a single DNA element. Science, 249, 1266-1272.
16. Dignam,J.D., Lebovitz,R.M. and Roeder,R.G. (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res., 11, 1475-1489.
17. II130. Cell, 87, 137-146.
18. Gilbert, S.F. (1991) Developmental Biology. Sinauer Associate, Inc., Sunderland, MA.
19. Gorman,C.M., Rigby,P.W.J. and Lane,D.P. (1985) Negative regulation of viral enhancers in undifferentiated embryonic stem cells. Cell, 42, 519-526.
20. Gstaiger,M., Knoepfel,L., Georglev,O., Schaffner,W. and Hovens,C.M. (1995) A B-cell coactivator of octamer-binding transcription factors. Nature, 373, 360-362.
21. Gu,W., Shi,X.-L. and Roeder,R.G. (1997) Synergistic activation of transcription by CBP and p53. Nature, 387, 819-823.
22. Hansen,S.K., Takada,S., Jacobson,R.H., Lis,J.T. and Tjian,R. (1997) Transcription properties of a cell type-specific TATA-binding protein, TRF. Cell, 91, 71-83.
23. Helin,K., Lees,J.A., Vidal,M., Dyson,N., Harlow,E. and Fattaey,A. (1992) A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F. Cell, 70, 337-350.
24. Helin,K., Wu,C.-L., Fattaey,A.R., Lees,J.A., Dynlacht,B.D., Ngwu,C. and Harlow,E. (1993) Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev., 7, 1850-1861.
25. Hen,R., Borrelli,E., Fromental,C., Sassone-Corsi,P. and Chambon,P. (1986) A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products. Nature, 321, 249-251.
26. Herrmann,B.G., Labeit,S., Poustka,A., King,T.R. and Lehrach,H. (1990) Cloning of the T gene required in mesoderm formation in the mouse. Nature, 343, 617-622.
27. Hoey,T., Warrior,R., Mank,J. and Levine,M. (1988) DNA-binding activities of the Drosophila melanogaster even-skipped protein are mediated by its homeodomain and influenced by protein context. Mol. Cell. Biol., 8, 4598-4607.
28. Hoffman,C.S. and Winston,F. (1987) A ten min DNA preparation from yeast efficiently releases autonomous plasmids for transformation of E.coli. Gene, 57, 267-272.
29. Hosler,B.A., LaRosa,G.P., Grippo,J.F. and Gudas,L.J. (1989) Expression of REX-1, a gene containing zinc finger motifs is rapidly reduced by retinoic acid in F9 teratocarcinoma cells. Mol. Cell Biol., 9, 5623-5629.
30. Imperiale,M.J., Kao,H.T., Feldman,L., Nevins,J. and Strickland,S. (1984) Common control of the heat shock gene and early adenovirus genes: Evidence for a cellular E1A-like activity. Mol. Cell. Biol., 4, 867-874.
31. Ito,H., Fukuoka,Y., Murata,K. and Kimura,A. (1983) Transformation of intact yeast cells treated with alkali cations. J. Bacteriol., 153, 163-168.
32. Kamei,Y. et al. (1996) A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell, 85, 403-414.
33. Keaveney,M., Berkenstam,A., Feigenbutz,M., Vriend,G. and Stunnenberg,H.G. (1993) Residues in the TATA-binding protein required to mediate a transcriptional response to retinoic acid in EC cells. Nature, 365, 562-566.
34. KelIy,F. and Condamine,H. (1982) Tumor viruses and early mouse embryos. Biochim. Biophys. Acta, 651, 105-141.
35. LaRosa,G.L. and Gudas,L.J. (1988) An early effect of retinoic acid: cloning of an mRNA (Era-1) exhibiting rapid and protein synthesis-independent induction during teratocarcinoma stem cell differentiation of murine embryonic carcinoma stem cells. Cell, 49, 507-513.
36. La Thangue,N.B. and Rigby,P.W.J. (1987) An adenovirus E1A-like transcription factor is regulated during differentiation of murine embryonic carcinoma stem cells. Cell, 49, 507-513.
37. Lee,K.A.W., Hai,T.-Y., Sivaraman,L., Thimmappaya,B., Hurst,H.C., Jones,N.C. and Green,M.R. (1987) A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters. Proc. Natl Acad. Sci. USA, 84, 8355-8359.
38. Lee,W.S., Kao,C.C., Bryant,G.O., Liu,X. and Berk,A.J. (1991) Adenovirus E1 A activation domain binds the basic repeat in the TATA box transcription factor. Cell, 67, 365-376.
39. Li, X.-Y. and Green,M.R. (1996) Intramolecular inhibition of activating transcription factor-2 function by its DNA-binding domain. Genes Dev., 10, 517-527.
40. Lill,N.L., Grossman,S.R., Ginsberg,D., DeCaprio,J. and Livingston,D.M. (1997) Binding and modulation of p53 by p300/CBP coactivators. Nature, 387, 823-827.
41. Liu,F. and Green,M.R. (1994) Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains. Nature, 368, 520-525.
42. Livingstone,C., Patel,G. and Jones,N. (1995) ATF-2 contains a phosphorylation-dependent transcriptional activation domain. EMBO J., 14, 1785-1797.
43. Luckow,B. and Schütz,G. (1987) CAT constructs with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements. Nucleic Acids Res., 15, 5490.
44. Luo,Y. and Roeder,R.G. (1995) Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol. Cell. Biol., 15, 4115-4124.
45. Maehara,Y., Fujiyoshi,T., Takahashi,T., Yamamoto,M. and Endo,H. (1985) 1.5 kb mRNA abundantly expressed in rat tumors encodes 37 kilodalton protein in vitro. Biochem. Biophys. Res. Commun., 131, 800-805.
46. Maekawa,T., Matsuda,S., Fujisawa,J., Yoshida,M. and Ishii,S. (1991) Cyclic AMP response element-binding protein, CRE-BP1, mediates the E1A-induced but not the Tax-induced trans-activation. Oncogene, 6, 627-632.
47. Martin,G.R. (1981) Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl Acad. Sci. USA, 78, 7634-7638.
48. Miyajima,A., Miyajima,I., Arai,K. and Arai,N. (1984) Expression of plasmid R388- encoded type II dihydrofolate reductase as a dominant selective marker in Saccharomyces cerevisiae. Mol. Cell. Biol., 4, 407-414.
49. Murphy,S.P., Garbern,J., Odenwald,W.F., Lazzarini,R.A. and Linney,E. (1988) Differential expression of the homeobox gene HOX-1-3 in F9 embryonic carcinoma cells. Proc. Natl Acad. Sci. USA. 85, 5587-5591.
50. Murray,E.J., Stott,D. and Rigby,P.W.J. (1991) Sequences and factors required for the F9 embryonic stem cell E1a-like activity. Mol. Cell. Biol., 11, 5534-5540.
51. Okamoto,K., Okazawa,H., Okuda,A., Sakai,M., Muramatsu,M. and Hamada,H. (1990) A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell. 60, 461-472.
52. Okayama,H., Kawaichi,M., Brownstein,M., Lee,F., Yokota,T. and Arai,K. (1987) High efficiency cloning of full-length cDNA. Methods Enzymol, 154, 3-28.
53. Okuda,A., Imagawa,M., Maeda,Y., Sakai,M. and Muramatsu,M. (1989) Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene. J. Biol. Chem., 264, 16919-16926.
54. Okuda,A.,Imagawa,M., Sakai,M. and Muramatsu,M. (1990) Functional cooperativity between two TPA responsive elements in undifferentiated F9 cells. EMBO J., 9, 1131-1135.
55. O'Reilly,D.R., MilIer,L.K. and Lukow,V.A. (1992) BACULOVIRUS EXPRESSION VECTORS. A Laboratory Manual. Oxford University Press, New York.
56. Rosner,M.H., Vigano,M.A., Ozato,K., Timmons,P.M., Poirier,F., Rigby,P.W.J. and Staudt,L.M. (1990) A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature, 345, 686-692.
57. Schöler,H.R., Ruppert,S., Suzuki,N., Chowdhury,K. and Gruss,P. (1990) New type of POU domain in germ line-specific protein Oct-4. Nature, 344, 435-439.
58. Schöler,H.R., Ciesiolka,T. and Gruss,P. (1991) A nexus between Oct-4 and E1A: Implications for gene regulation in embryonic stem cells. Cell, 66, 291-304.
59. Shew,J.-Y., Lin,B.T.-Y., Chen,P.-L., Tseng,B.Y., Yang-Feng,T. and Lee,W.-H. (1990) C-terminal truncation of the retinoblastoma gene product leads to functional inactivation. Proc. Natl Acad. Sci. USA, 87, 6-10.
60. Sikorski,R.S. and Hieter,P. (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics, 122, 19-27.
61. Strubin,M., Newell,J.W. and Matthias,P. (1995) OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell, 80, 497-506.
62. Tanaka,K., Nakafuku,M.,Tamanoi,F., Kaziro,Y., Matsumoto,K. and Toh-e, A. (1990) IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol. Cell. Biol., 10, 4303-4313.
63. Verrijzer,C.P. and Tjian,R. (1996) TAFs mediate transcriptional activation and promoter selectivity. Trends Biochem. Sci., 21, 338-342.
64. Wagner,S. and Green,M.R. (1993) HTLV-1 Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization. Science, 262, 395-399.
65. Wilkinson, D.G. (1992) Whole mount in situ hybridization of vertebrate embryos. In Wilkinson,D.G. (ed.). In situ hybridization. A practical approach. IRL Press, Oxford, pp. 75-83.
66. Xin,J.-H., Cowie,A., Lachance,P. and Hassell,J.A. (1992) Molecular cloning and characterization of PEA3, a new member of the Ets oncoprotein family that is differentially expressed in mouse embryonic cells. Genes Dev. 6, 481-496.
67. Yang-Yen,H.-F., Chambard,J.-C., Sun,Y.-L., Smeal,T., Schmidt,T.J., Drouin,J. and Karin, M. (1990) Transcriptional interference between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell, 62, 1205-1215.
68. Yao,Y., Yamamoto,K., Nishi,Y. Nogi,Y. and Muramatsu,M. (1996) Mouse RNA polymerase I 16-kDa subunit able to associate with 40-kDa subunit is a homolog of yeast AC19 subunit of RNA polymerase I and III. J. Biol. Chem., 271, 32881-32885.
69. Yuan,H., Corbi,N., Basilico,C. and Dailey,L. (1995) Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev., 9, 2635-2645.
70. Zhou,Q., Boyer,T.G. and Berg,A.J. (1993) Factors (TAFs) required for activated transcription interact with TATA box-binding protein conserved core domain. Genes Dev., 7, 180-187.