In vivo selection of lethal mutations reveals two functional domains in arginyl-tRNA synthetase

RNA

Volumn 6, Issue 3, 2000, Pages 434-448

  Geslain, Renaud ^a   Martin, Franck ^a   Delagoutte, Bénédicte ^b   Cavarelli, Jean ^b   Gangloff, Jean ^a   Eriani, Gilbert ^a,c  

^a CNRS   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Aminoacyl tRNA synthetase; Genetic screen; Kinetic analysis; Mutants; Substrate recognition

Indexed keywords

ARGININE; ARGININE TRANSFER RNA LIGASE; TRANSFER RNA;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ESCHERICHIA COLI; GENETIC SCREENING; KINETICS; MUTAGENESIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SACCHAROMYCES CEREVISIAE; YEAST;

ARGININE-TRNA LIGASE; CLONING, MOLECULAR; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, FUNGAL; GENES, LETHAL; KINETICS; MODELS, MOLECULAR; MUTATION; PEPTIDE FRAGMENTS; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI; EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0034106754     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838200992331     Document Type: Article

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