Immunoreactive thromboxane synthase is measurable in ovine fetal hypothalamus as early as 86 days' gestation

Prostaglandins

Volumn 54, Issue 2, 1997, Pages 569-579

  Wood, Charles E ^a   Purinton, Scott ^a   Cudd, Timothy A ^a  

^a NONE

Author keywords

Brain; Central nervous system; Endocrinology; Fetus; Sheep; Thromboxane

Indexed keywords

THROMBOXANE SYNTHASE;

AGE; ANIMAL TISSUE; ARTICLE; BRAIN STEM; ENZYME ANALYSIS; ENZYME LOCALIZATION; FETUS; FETUS LUNG; GESTATIONAL AGE; HYPOPHYSIS; HYPOTHALAMUS; IMMUNOREACTIVITY; MOLECULAR WEIGHT; NEWBORN; NONHUMAN; SHEEP; TISSUE DISTRIBUTION;

ANIMALS; BRAIN STEM; GESTATIONAL AGE; HYPOTHALAMUS; LUNG; MOLECULAR WEIGHT; PITUITARY GLAND; SHEEP; THROMBOXANE-A SYNTHASE;

EID: 0030749342     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(97)00126-3     Document Type: Article

References (16)

1. Wood C.E., Cudd T.A., Kane C., Engelke K. Fetal ACTH and blood pressure responses to thromboxane mimetic U46619. Am. J. Physiol. 265:1993;R858.
2. Cudd T.A., Wood C.E. Thromboxane A2 receptor antagonism prevents the hormonal and cardiovascular responses to mineral acid infusion. Am. J. Physiol. 267:1994;R1235.
3. Bernardini R., Chiarenza A., Calogero A.E., Gold P.W., Chrousos G.P. Arachidonic acid metabolites modulate rat hypothalamic corticotropin releasing hormone in vitro. Neuroendocrinology. 50:1989;708.
4. Campbell, W.B. In: Goodman and Gilman's The Pharmacological Basis of Therapeutics. Lipid-derived autacoids: eicosanoids and platelet-activating factor. (Ed. Gilman, A.G., Rall, T.W., Nies, A.S., and Taylor, P. eds.) 600-617. (Pergamon Press: New York.) 1990.
5. Chemtob S., Beharry K., Rex J., Varma D.R., Aranda J.V. Changes in cerebrovascular prostaglandins and thromboxane as a function of systemic blood pressure. Circ. Res. 67:1990;674.
6. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;681.
7. Bradford M.M. A refined and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochem. 72:1976;248.
8. Winer, B.J. 1971. 'Statistical Principles in Experimental Design' (McGraw-Hill:New York.).
9. Pettigrew L.C., Kryscio R.J. Thromboxane receptor antagonism and synthase inhibition in cerebral ischemia. Prostaglandins Leukotrienes & Essent. Fatty Acids. 48:1993;211.
10. Woods L.L. Importance of prostaglandins in hypertension during reduced uteroplacenatal perfusion pressure. Am. J. Physiol. 257:1989;R1558.
11. Cudd T.A., Wood C.E. Prostanoid cascade inhibition prevents the cardiovascular and adrenocorticotropic responses to mineral acid infusion in conscious sheep. Am. J. Physiol. 264:1993;R1235.
12. Ohashi K., Ruan R.J., Kulmacz R.J., Wu K.K., Wang L.-H. Primary structure of human thromboxane synthase determined from the cDNA sequence. J. Biol. Chem. 267:1992;789.
13. Haurand M., Ullrich V. Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme. J. Biol. Chem. 260:1985;15059.
14. Shen R.-F., Tai H.-H. Immunoaffinity purification and characterization of thromboxane synthase from porcine lung. J. Biol. Chem. 261:1986;11592.
15. Shen R.-F., Tai H.-H. Immunological studies on thromboxane synthase. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 17:1987;34.
16. 2 synthase. J. Biol. Chem. 265:1990;20166.