Labelling of retinal microglial cells following an intravenous injection of a fluorescent dye into rats of different ages

Journal of Anatomy

Volumn 196, Issue 2, 2000, Pages 173-179

  Zeng, Xiao Xia ^a   Ng, Yee Kong ^a   Ling, Eng Ang ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Blood retinal barrier; ED 1; Microglia; OX 42; RhIc

Indexed keywords

ANTIBODY; FLUORESCENT DYE; R 1755; RHODAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; IMMUNOHISTOCHEMISTRY; MICROGLIA; NERVE CELL; NERVE FIBER; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA; RETINA BLOOD VESSEL;

AGING; ANIMALS; BLOOD-RETINAL BARRIER; FLUORESCENT DYES; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; MACROPHAGE-1 ANTIGEN; MICROGLIA; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; RATS; RATS, WISTAR; RETINA; RHODAMINES;

ANIMALIA;

EID: 0034098862     PISSN: 00218782     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0021878299005853     Document Type: Article

References (23)

1. ALM A, TORNQUIST P (1981) The uptake index method applied to studies on the blood-retinal barrier. I. A methodological study. Acta Physiologica Scandinavica 113, 73-79.
2. ASHWELL K (1989) Development of microglia in the albino rabbit retina. Journal of Comparative Neurology 287, 286-301.
3. ASHWELL K, HOLLANDER H, STREIT W, STONE J (1989) The appearance and distribution of microglia in the developing retina of the rat. Visual Neuroscience 2, 437-448.
4. CUNHA-VAZ JG, SHAKIB M, ASHTON N (1966) Studies on the permeability of the blood-retinal barrier. I. On the existence, development and site of a blood-retinal barrier. British Journal of Ophthalmology 50, 441-453.
5. DIAZ-ARAYA CM, PROVIS JM, PENFOLD PL (1995) Ontogeny and cellular expression of MHC and leucocyte antigens in human retina. Glia 15, 458-470.
6. EGENSPERGER R, MASLIM J, BISTI S, HOLLANDER H, STONE J (1996) Fate of DNA from retinal cells dying during development: uptake by microglia and macroglia (Müller cells). Brain Research. Developmental Brain Research 97, 1-8.
7. ENNIS SR, BETZ AL (1986) Sucrose permeability of the blood-retinal and blood-brain barriers. Effects of diabetes, hypertonicity, and iodate. Investigative Ophthalmology & Visual Science 27, 1095-1102.
8. HUME DA, PERRY VH, GORDON S (1983) Immunohistochemical localization of a macrophage-specific antigen in developing mouse retina: phagocytosis of dying neurons and differentiation of microglial cells to form a regular array in the plexiform layers. Journal of Cell Biology 97, 253-257.
9. KACZA J, SEEGER J (1997) Transcellular labelling of activated retinal microglia following transection of the optic nerve. Inflammation Research 46, 430-433.
10. KAUR C, LING EA, WONG WC (1986) Labelling of amoeboid microglial cells in rats of various ages following an intravenous injection of horseradish peroxidase. Acta Anatomica 125, 132-137.
11. LEONG SK, LING EA (1992) Amoeboid and ramified microglia: their interrelationship and response to brain injury. Glia 6, 39-47.
12. LI YB, KAUR C, LING EA (1997) Labelling of amoeboid microglial cells and intraventricular macrophages in fetal rats following a maternal injection of a fluorescent dye. Neuroscience Research 28, 119-125.
13. LING EA (1979) Transformation of monocytes into amoeboid microglia and into microglia in the corpus callosum of postnatal rats, as shown by labelling monocytes by carbon particles. Journal of Anatomy 128, 847-858.
14. LING EA (1982) A light microscopic demonstration of amoeboid microglia and microglial cells in the retina of rats of various ages. Archivum Histologicum Japonicum 45, 37-44.
15. PEARSON HE, PAYNE BR, CUNNINGHAM TJ (1993) Microglial invasion and activation in response to naturally occurring neuronal degeneration in the ganglion cell layer of the postnatal cat retina. Developmental Brain Research 76, 249-255.
16. PROVIS JM, DIAZ CM, PENFOLD PL (1996) Microglia in human retina: a heterogeneous population with distinct ontogenies. Developmental Neurobiology 3, 213-222.
17. SCHNITZER J (1989) Enzyme-histochemical demonstration of microglial cell in the adult and postnatal rabbit retina. Journal of Comparative Neurology 282, 249-263.
18. SCHNITZER J, SCHERER J (1990) Microglial cells responses in the rabbit retina following transection of the optic nerve. Journal of Comparative Neurology 302, 779-791.
19. STEWART PA, TUOR UI (1994) Blood-eye barriers in the rat: correlation of ultrastructure with function. Journal of Comparative Neurology 340, 566-576.
20. VINORES SA (1995) Assessment of blood-retinal barrier integrity. Histology and Histopathology 10, 141-154.
21. XU J, KAUR C, LING EA (1993) Variation with age in the labelling of amoeboid microglial cells in rats following intraperitoneal or intravenous injection of a fluorescent dye. Journal of Anatomy 182, 55-63.
22. XU J, LING EA (1994) Studies of the distribution and functional roles of transitory amoeboid microglial cells in developing rat brain using exogenous horseradish peroxidase as a marker. Journal für Hirnforschung 35, 103-111.
23. XU J, LING EA (1994) Studies of the ultrastructure and permeability of the blood-brain barrier in the developing corpus callosum in postnatal rat brain using electron dense tracers. Journal of Anatomy 184, 227-237.