-
1
-
-
0028150639
-
Metabolism of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in isolated liver cells from guinea pig, hamster, mouse, and rat
-
Alexander, J., B. H. Fossum & J. A. Holme: Metabolism of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in isolated liver cells from guinea pig, hamster, mouse, and rat. Environ. Health Perspect. 1994, 102, 109-114.
-
(1994)
Environ. Health Perspect.
, vol.102
, pp. 109-114
-
-
Alexander, J.1
Fossum, B.H.2
Holme, J.A.3
-
2
-
-
0002488834
-
Metabolic fate of heterocyclic amines from cooked food
-
Ed.: H. Hayatsu. CRC Press, Boca Raton, Florida, USA
-
Alexander, J. & H. Wallin: Metabolic fate of heterocyclic amines from cooked food. In: Mutagens in food: Detection and prevention. Ed.: H. Hayatsu. CRC Press, Boca Raton, Florida, USA, 1991, pp. 143-156.
-
(1991)
Mutagens in Food: Detection and Prevention
, pp. 143-156
-
-
Alexander, J.1
Wallin, H.2
-
3
-
-
0023629080
-
Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: Preliminary findings
-
Bird, R. P.: Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett. 1987, 37, 147-151.
-
(1987)
Cancer Lett.
, vol.37
, pp. 147-151
-
-
Bird, R.P.1
-
4
-
-
0025344002
-
Human arylamine N-acetyltransferase genes: Isolation, chromosomal localization, and functional expression
-
Blum, M., D. M. Grant, W. McBride, M. Heim & U. A. Meyer: Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression. DNA Cell Biol. 1990, 9, 193-203.
-
(1990)
DNA Cell Biol.
, vol.9
, pp. 193-203
-
-
Blum, M.1
Grant, D.M.2
McBride, W.3
Heim, M.4
Meyer, U.A.5
-
5
-
-
0032146178
-
A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer
-
Chen, J., M. J. Stampfer, H. L. Hough, M. Garcia-Closas, W. C. Willett, C. H. Hennekens, K. T. Kelsey & D. J. Hunter: A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer. Cancer Res. 1998, 58, 3307-3311.
-
(1998)
Cancer Res.
, vol.58
, pp. 3307-3311
-
-
Chen, J.1
Stampfer, M.J.2
Hough, H.L.3
Garcia-Closas, M.4
Willett, W.C.5
Hennekens, C.H.6
Kelsey, K.T.7
Hunter, D.J.8
-
6
-
-
0000617487
-
Carcinogenic aromatic amines and amides
-
Eds.: I. G. Sipes, C. A. McQueen & A. J. Gandolfi. Elsevier Science Ltd., Oxford, UK
-
Delclos, K. B. & F. F. Kadlubar: Carcinogenic aromatic amines and amides. In: Comprehensive toxicology. Eds.: I. G. Sipes, C. A. McQueen & A. J. Gandolfi. Elsevier Science Ltd., Oxford, UK, 1997, pp. 141-170.
-
(1997)
Comprehensive Toxicology
, pp. 141-170
-
-
Delclos, K.B.1
Kadlubar, F.F.2
-
7
-
-
0024854930
-
Induction of lymphoma in CDF, mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Esumi, H., H. Ohgaki, E. Kohzen, S. Takayama & T. Sugimura: Induction of lymphoma in CDF, mice by the food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jap. J. Cancer Res. 1989, 80, 1176-1178.
-
(1989)
Jap. J. Cancer Res.
, vol.80
, pp. 1176-1178
-
-
Esumi, H.1
Ohgaki, H.2
Kohzen, E.3
Takayama, S.4
Sugimura, T.5
-
8
-
-
0024345871
-
N-acetyltransferase
-
Evans, D. A. P.: N-acetyltransferase. Pharmacol. Therap. 1989, 42, 157-234.
-
(1989)
Pharmacol. Therap.
, vol.42
, pp. 157-234
-
-
Evans, D.A.P.1
-
9
-
-
0030725239
-
Higher frequency of aberrant crypt foci in rapid than slow acetylator inbred rats administered the colon carcinogen 3,2′-dimethyl-4-aminobiphenyl
-
Feng, Y., A. J. Fretland, T. D. Rustan, W. Jiang, W. K. Becker & D. W. Hein: Higher frequency of aberrant crypt foci in rapid than slow acetylator inbred rats administered the colon carcinogen 3,2′-dimethyl-4-aminobiphenyl. Toxicol. Appl. Pharmacol. 1997, 147, 56-62.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.147
, pp. 56-62
-
-
Feng, Y.1
Fretland, A.J.2
Rustan, T.D.3
Jiang, W.4
Becker, W.K.5
Hein, D.W.6
-
10
-
-
0030040622
-
Acetylator genotype (NAT2)-dependent formation of aberrant crypts in congenic Syrian hamsters administered 3,2′-dimethyl-4-aminobiphenyl
-
Feng, Y., R. J. Wagner, A. J. Fretland, W. K. Becker, A. M. Cooley, T. P. Pretlow, K. J. Lee & D. W. Hein: Acetylator genotype (NAT2)-dependent formation of aberrant crypts in congenic Syrian hamsters administered 3,2′-dimethyl-4-aminobiphenyl. Cancer Res. 1996a, 56, 527-531.
-
(1996)
Cancer Res.
, vol.56
, pp. 527-531
-
-
Feng, Y.1
Wagner, R.J.2
Fretland, A.J.3
Becker, W.K.4
Cooley, A.M.5
Pretlow, T.P.6
Lee, K.J.7
Hein, D.W.8
-
11
-
-
0030273392
-
3,2′-Dimethyl-4-aminobiphenyl-DNA adduct formation in tumor target and non-target organs of rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus
-
Feng, Y, W. Jiang, A. C. Deitz & D. W. Hein: 3,2′-Dimethyl-4-aminobiphenyl-DNA adduct formation in tumor target and non-target organs of rapid and slow acetylator Syrian hamsters congenic at the NAT2 locus. Toxicol. Appl. Pharmacol. 1996b, 140, 315-321.
-
(1996)
Toxicol. Appl. Pharmacol.
, vol.140
, pp. 315-321
-
-
Feng, Y.1
Jiang, W.2
Deitz, A.C.3
Hein, D.W.4
-
12
-
-
0028207404
-
Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters
-
Ferguson, R. J., M. A. Doll, B. R. Baumstark & D. W. Hein: Polymorphic arylamine N-acetyltransferase encoding gene (NAT2) from homozygous rapid and slow acetylator congenic Syrian hamsters. Gene 1994a 140, 247-249.
-
(1994)
Gene
, vol.140
, pp. 247-249
-
-
Ferguson, R.J.1
Doll, M.A.2
Baumstark, B.R.3
Hein, D.W.4
-
13
-
-
0028358566
-
Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: Amplification, cloning, sequencing, and expression in E. coli
-
Ferguson, R. J., M. A. Doll, T. D. Rustan, B. R. Baumstark & D. W. Hein: Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: amplification, cloning, sequencing, and expression in E. coli. Pharmacogenetics 1994b, 4, 82-90.
-
(1994)
Pharmacogenetics
, vol.4
, pp. 82-90
-
-
Ferguson, R.J.1
Doll, M.A.2
Rustan, T.D.3
Baumstark, B.R.4
Hein, D.W.5
-
14
-
-
0029869584
-
Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyltransferase encoding genes of the Syrian hamster
-
Ferguson, R. J., M. A. Doll, T. D. Rustan & D. W. Hein: Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyltransferase encoding genes of the Syrian hamster. Pharmacogenetics 1996, 6, 55-66.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 55-66
-
-
Ferguson, R.J.1
Doll, M.A.2
Rustan, T.D.3
Hein, D.W.4
-
15
-
-
0019833918
-
The effect of disulfiram on the carcinogenicity of 3,2′-dimethyl-4-aminobiphenyl in Syrian golden hamsters and rats
-
Fiala, E. S., J. H. Weisburger, S. Katayama, V. Chandrasekaran & G. M. Williams: The effect of disulfiram on the carcinogenicity of 3,2′-dimethyl-4-aminobiphenyl in Syrian golden hamsters and rats. Carcinogenesis 1981, 2, 965-969.
-
(1981)
Carcinogenesis
, vol.2
, pp. 965-969
-
-
Fiala, E.S.1
Weisburger, J.H.2
Katayama, S.3
Chandrasekaran, V.4
Williams, G.M.5
-
16
-
-
0027476961
-
Molecular genetics of the N-acetyltransferases
-
Grant, D. M.: Molecular genetics of the N-acetyltransferases. Pharmacogenetics 1993, 3, 45-50.
-
(1993)
Pharmacogenetics
, vol.3
, pp. 45-50
-
-
Grant, D.M.1
-
17
-
-
0025967717
-
Monomorphic and polymorphic human arylamine N-acetyltransferases: A comparison of liver isozymes and expressed products of two cloned genes
-
Grant, D. M., M. Blum, M. Beer & U. A. Meyer: Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. Mol. Pharmacol. 1991, 39, 184-191.
-
(1991)
Mol. Pharmacol.
, vol.39
, pp. 184-191
-
-
Grant, D.M.1
Blum, M.2
Beer, M.3
Meyer, U.A.4
-
18
-
-
0028190698
-
N-acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: Enzymology and bioactivation
-
Hanna, P. E.: N-Acetyltransferases, O-acetyltransferases, and N,O-acetyltransferases: enzymology and bioactivation. Adv. Pharmacol. 1994, 27, 401-430.
-
(1994)
Adv. Pharmacol.
, vol.27
, pp. 401-430
-
-
Hanna, P.E.1
-
19
-
-
0027787536
-
Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenicity in rats
-
Hasegawa, R., M. Sano, S. Tamano, K. Imaida, T. Shirai, M. Nagao, T. Sugimura & N. Ito. Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenicity in rats. Carcinogenesis 1993, 14, 2553-2557.
-
(1993)
Carcinogenesis
, vol.14
, pp. 2553-2557
-
-
Hasegawa, R.1
Sano, M.2
Tamano, S.3
Imaida, K.4
Shirai, T.5
Nagao, M.6
Sugimura, T.7
Ito, N.8
-
20
-
-
0023812845
-
Acetylator genotype and arylamine-induced carcinogenesis
-
Hein, D. W.: Acetylator genotype and arylamine-induced Carcinogenesis. Biochim. Biophys. Acta 1988, 948, 37-66.
-
(1988)
Biochim. Biophys. Acta
, vol.948
, pp. 37-66
-
-
Hein, D.W.1
-
21
-
-
0002063453
-
A new model for toxic risk assessments: Construction of homozygous rapid and slow acetylator congenic Syrian hamster lines
-
Hein, D. W.: A new model for toxic risk assessments: construction of homozygous rapid and slow acetylator congenic Syrian hamster lines. Toxicol. Methods 1991, 1, 44-52.
-
(1991)
Toxicol. Methods
, vol.1
, pp. 44-52
-
-
Hein, D.W.1
-
22
-
-
12644293822
-
Rodent models of the human acetylation polymorphism: Comparisons of recombinant acetyltransferases
-
Hein, D. W., M. A. Doll, A. J. Fretland, K. Gray, A. C. Deitz, Y. Feng, W. Jiang, T. D. Rustan, S. L. Satran & T. R. Wilkie, Sr.: Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases. Mutat. Res. 1997a, 376, 101-106.
-
(1997)
Mutat. Res.
, vol.376
, pp. 101-106
-
-
Hein, D.W.1
Doll, M.A.2
Fretland, A.J.3
Gray, K.4
Deitz, A.C.5
Feng, Y.6
Jiang, W.7
Rustan, T.D.8
Satran, S.L.9
Wilkie T.R., Sr.10
-
23
-
-
0033960051
-
Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms
-
Hein, D. W., M. A. Doll, A. J. Fretland, M. A. Leff, S. J. Webb, G. H. Xiao, U.-S. Devanaboyina, N. A. Nangju & Y. Feng: Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms. Cancer Epidemiol. Biomarkers Prev. 2000, 9, 29-42.
-
(2000)
Cancer Epidemiol. Biomarkers Prev.
, vol.9
, pp. 29-42
-
-
Hein, D.W.1
Doll, M.A.2
Fretland, A.J.3
Leff, M.A.4
Webb, S.J.5
Xiao, G.H.6
Devanaboyina, U.-S.7
Nangju, N.A.8
Feng, Y.9
-
24
-
-
0027477877
-
Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus
-
Hein, D. W., M. A. Doll, K. Gray, T. D. Rustan & R. J. Ferguson: Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus. Cancer Res. 1993a, 53, 509-514.
-
(1993)
Cancer Res.
, vol.53
, pp. 509-514
-
-
Hein, D.W.1
Doll, M.A.2
Gray, K.3
Rustan, T.D.4
Ferguson, R.J.5
-
25
-
-
0028301762
-
Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): Acetylator genotype-dependent N-and O-acetylation of arylamine carcinogens
-
Hein, D. W., M. A. Doll, T. D. Rustan, K. Gray, R. J. Ferguson & Y. Feng: Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N-and O-acetylation of arylamine carcinogens. Toxicol. Appl. Pharmacol. 1994, 124, 16-24.
-
(1994)
Toxicol. Appl. Pharmacol.
, vol.124
, pp. 16-24
-
-
Hein, D.W.1
Doll, M.A.2
Rustan, T.D.3
Gray, K.4
Ferguson, R.J.5
Feng, Y.6
-
26
-
-
0027281895
-
Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases
-
Hein, D. W., M. A. Doll, T. D. Rustan, K. Gray, Y. Feng, R. J. Ferguson & D. M. Grant: Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Carcinogenesis 1993b, 14, 1633-1638.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1633-1638
-
-
Hein, D.W.1
Doll, M.A.2
Rustan, T.D.3
Gray, K.4
Feng, Y.5
Ferguson, R.J.6
Grant, D.M.7
-
27
-
-
0030904330
-
Recombinant expression and catalytic analysis of rapid and slow acetylator Syrian hamster chimeric NAT2 alleles
-
Hein, D. W., R. J. Ferguson, M. A. Doll & A. C. Deitz: Recombinant expression and catalytic analysis of rapid and slow acetylator Syrian hamster chimeric NAT2 alleles. Arch. Toxicol. 1997b, 71, 306-313.
-
(1997)
Arch. Toxicol.
, vol.71
, pp. 306-313
-
-
Hein, D.W.1
Ferguson, R.J.2
Doll, M.A.3
Deitz, A.C.4
-
28
-
-
0022415085
-
Biochemical investigation of the basis for the genetic N-acetylation polymorphism in the inbred hamster
-
Mein, D. W., W. G. Kirlin, R. J. Ferguson & W. W. Weber: Biochemical investigation of the basis for the genetic N-acetylation polymorphism in the inbred hamster. J. Pharmacol. Exp. Therap. 1985, 234, 358-364.
-
(1985)
J. Pharmacol. Exp. Therap.
, vol.234
, pp. 358-364
-
-
Mein, D.W.1
Kirlin, W.G.2
Ferguson, R.J.3
Weber, W.W.4
-
29
-
-
0025768966
-
A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
-
Ito, N., R. Hasegawa, M. Sano, S. Tamano, H. Esumi, S. Takayama & T. Sugimura: A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Carcinogenesis 1991, 12, 1503-1506.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1503-1506
-
-
Ito, N.1
Hasegawa, R.2
Sano, M.3
Tamano, S.4
Esumi, H.5
Takayama, S.6
Sugimura, T.7
-
30
-
-
0033135468
-
Higher DNA adduct levels in urinary bladder and prostate of slow acetylator inbred rats administered 3,2′-dimethyl-4-aminobiphenyl
-
Jiang, W., Y. Feng & D. W. Hein: Higher DNA adduct levels in urinary bladder and prostate of slow acetylator inbred rats administered 3,2′-dimethyl-4-aminobiphenyl. Toxicol. Appl. Pharmacol. 1999, 156, 187-194.
-
(1999)
Toxicol. Appl. Pharmacol.
, vol.156
, pp. 187-194
-
-
Jiang, W.1
Feng, Y.2
Hein, D.W.3
-
31
-
-
0029760028
-
Recombinant rat and hamster N-acetyltransferases-1 and -2: Relative rates of N-acetylation of arylamines and N,O-acyltransfer with arylhydroxamic acids
-
Jones, R. F., S. J. Land & C. M. King: Recombinant rat and hamster N-acetyltransferases-1 and -2: relative rates of N-acetylation of arylamines and N,O-acyltransfer with arylhydroxamic acids. Carcinogenesis 1996, 17, 1729-1733.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1729-1733
-
-
Jones, R.F.1
Land, S.J.2
King, C.M.3
-
32
-
-
0027076179
-
Polymorphisms for aromatic amine metabolism in humans: Relevance for human carcinogenesis
-
Kadlubar, F. F., M. A. Butler, K. R. Kaderlik, H.-C. Chou & N. P. Lang: Polymorphisms for aromatic amine metabolism in humans: relevance for human carcinogenesis. Environ. Health Perspect. 1992, 98, 69-74.
-
(1992)
Environ. Health Perspect.
, vol.98
, pp. 69-74
-
-
Kadlubar, F.F.1
Butler, M.A.2
Kaderlik, K.R.3
Chou, H.-C.4
Lang, N.P.5
-
33
-
-
0027999623
-
Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps
-
Lang, N. P., M. A. Butler, J. Massengill, M. Lawson, R. C. Stotts, M. Hauer-Jensen & F. F. Kadlubar: Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps. Cancer Epidemiol. Biomarkers Prev. 1994, 3, 675-682.
-
(1994)
Cancer Epidemiol. Biomarkers Prev.
, vol.3
, pp. 675-682
-
-
Lang, N.P.1
Butler, M.A.2
Massengill, J.3
Lawson, M.4
Stotts, R.C.5
Hauer-Jensen, M.6
Kadlubar, F.F.7
-
34
-
-
0028835983
-
Cancer risk of heterocyclic amines in cooked foods: An analysis and implications for research
-
Layton, D. W., K. T. Bogen, M. G. Knize, F. T. Hatch, V. M. Johnson & J. S. Felton: Cancer risk of heterocyclic amines in cooked foods: an analysis and implications for research. Carcinogenesis 1995, 16, 39-52.
-
(1995)
Carcinogenesis
, vol.16
, pp. 39-52
-
-
Layton, D.W.1
Bogen, K.T.2
Knize, M.G.3
Hatch, F.T.4
Johnson, V.M.5
Felton, J.S.6
-
35
-
-
0032967592
-
Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse
-
Leff, M. A., P. N. Epstein, M. A. Doll, A. J. Fretland, U.-S. Devanaboyina, T. D. Rustan & D. W. Hein: Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse. J. Pharmacol. Exp. Therap. 1999, 290, 182-187.
-
(1999)
J. Pharmacol. Exp. Therap.
, vol.290
, pp. 182-187
-
-
Leff, M.A.1
Epstein, P.N.2
Doll, M.A.3
Fretland, A.J.4
Devanaboyina, U.-S.5
Rustan, T.D.6
Hein, D.W.7
-
36
-
-
0026783540
-
Identification of N-(deoxyguanosin-8-y1)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA
-
Lin, D., K. R. Kaderlik, R. J. Turesky, D. W. Miller, J. O. Lay, Jr. & F. F. Kadlubar: Identification of N-(deoxyguanosin-8-y1)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine as the major adduct formed by the food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, with DNA. Chem. Res. Toxicol. 1992, 5, 691-697.
-
(1992)
Chem. Res. Toxicol.
, vol.5
, pp. 691-697
-
-
Lin, D.1
Kaderlik, K.R.2
Turesky, R.J.3
Miller, D.W.4
Lay J.O., Jr.5
Kadlubar, F.F.6
-
37
-
-
0028904047
-
Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice
-
Lin, D.-X., N. P. Lang & F. F. Kadlubar: Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice. Drug Metab. Dispos. 1995, 23, 518-524.
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 518-524
-
-
Lin, D.-X.1
Lang, N.P.2
Kadlubar, F.F.3
-
38
-
-
0027527140
-
Carcinogenic factors in food with relevance to colon cancer development
-
Nagao, M. & T. Sugimura: Carcinogenic factors in food with relevance to colon cancer development. Mutat. Res. 1993, 290, 43-51.
-
(1993)
Mutat. Res.
, vol.290
, pp. 43-51
-
-
Nagao, M.1
Sugimura, T.2
-
39
-
-
0020644905
-
In vivo metabolism of 3,2′-dimethyl-4-aminobiphenyl (DMAB) bearing on its organotropism in the Syrian golden hamster and the F344 rat
-
Nussbaum, M., E. S. Fiala, B. Kulkarni, K. El-Bayoumy & J. H. Weisburger: In vivo metabolism of 3,2′-dimethyl-4-aminobiphenyl (DMAB) bearing on its organotropism in the Syrian golden hamster and the F344 rat. Environ. Health Perspect. 1983, 49, 223-231.
-
(1983)
Environ. Health Perspect.
, vol.49
, pp. 223-231
-
-
Nussbaum, M.1
Fiala, E.S.2
Kulkarni, B.3
El-Bayoumy, K.4
Weisburger, J.H.5
-
40
-
-
0025800944
-
Induction of intestinal adenocarcinomas by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Nagase analbuminemic rats
-
Ochiai, M., K. Ogawa, K. Wakabayashi, T. Sugimura, S. Nagase, H. Esumi & M. Nagao: Induction of intestinal adenocarcinomas by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Nagase analbuminemic rats. Jap. J. Cancer Res. 1991, 82, 363-366.
-
(1991)
Jap. J. Cancer Res.
, vol.82
, pp. 363-366
-
-
Ochiai, M.1
Ogawa, K.2
Wakabayashi, K.3
Sugimura, T.4
Nagase, S.5
Esumi, H.6
Nagao, M.7
-
41
-
-
0021200973
-
Carcinogenicity in mice of a mutagenic compound, 2-amino-3-methylimidazo[4,5-f]quinoline, from broiled sardine, cooked beef and beef extract
-
Ohgaki, H., K. Kusama, N. Matsukura, K. Morino, H. Hasegawa, S. Sato, S. Takayama & T. Sugimura: Carcinogenicity in mice of a mutagenic compound, 2-amino-3-methylimidazo[4,5-f]quinoline, from broiled sardine, cooked beef and beef extract. Carcinogenesis 1984, 5, 921-924.
-
(1984)
Carcinogenesis
, vol.5
, pp. 921-924
-
-
Ohgaki, H.1
Kusama, K.2
Matsukura, N.3
Morino, K.4
Hasegawa, H.5
Sato, S.6
Takayama, S.7
Sugimura, T.8
-
42
-
-
0025695732
-
Monomorphic and polymorphic isozymes of arylamine N-acetyltransferases in hamster liver: Purification of the isozymes and genetic basis of N-acetylation polymorphism
-
Ozawa, S., M. Abu-Zeid, Y. Kawakubo, S. Toyama, Y. Yamazoe & R. Kato: Monomorphic and polymorphic isozymes of arylamine N-acetyltransferases in hamster liver: purification of the isozymes and genetic basis of N-acetylation polymorphism. Carcinogenesis 1990, 11, 2137-2144.
-
(1990)
Carcinogenesis
, vol.11
, pp. 2137-2144
-
-
Ozawa, S.1
Abu-Zeid, M.2
Kawakubo, Y.3
Toyama, S.4
Yamazoe, Y.5
Kato, R.6
-
43
-
-
0029928585
-
Effect of acetylator genotype on 3,2′-dimethyl-4-aminobiphenyl induced aberrant crypt foci in the colon of hamsters
-
Paulsen, J. E., I.-L. Steffensen, E. Namork, D. W. Hein & J. Alexander: Effect of acetylator genotype on 3,2′-dimethyl-4-aminobiphenyl induced aberrant crypt foci in the colon of hamsters. Carcinogenesis 1996, 17, 459-465.
-
(1996)
Carcinogenesis
, vol.17
, pp. 459-465
-
-
Paulsen, J.E.1
Steffensen, I.-L.2
Namork, E.3
Hein, D.W.4
Alexander, J.5
-
44
-
-
0033982771
-
Association between acetylator genotype and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) DNA adduct formation in colon and prostate of inbred Fischer 344 and Wistar Kyoto rats
-
Purewal, M., A. J. Fretland, H. A. J. Schut, D. W. Hein & M. J. Wargovich: Association between acetylator genotype and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) DNA adduct formation in colon and prostate of inbred Fischer 344 and Wistar Kyoto rats. Cancer Lett. 2000a, 149, 53-60.
-
(2000)
Cancer Lett.
, vol.149
, pp. 53-60
-
-
Purewal, M.1
Fretland, A.J.2
Schut, H.A.J.3
Hein, D.W.4
Wargovich, M.J.5
-
45
-
-
0034023575
-
2-Amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine induces a higher number of aberrant crypt foci in Fischer-344 (rapid) than Wistar Kyoto (slow) acetylator inbred rats
-
in press
-
Purewal, M., M. Velasco, A. J. Fretland, D. W. Hein & M. J. Wargovick: 2-Amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine induces a higher number of aberrant crypt foci in Fischer-344 (rapid) than Wistar Kyoto (slow) acetylator inbred rats. Cancer Epidemiol. Biomarkers Prev. 2000b, 9, in press.
-
(2000)
Cancer Epidemiol. Biomarkers Prev.
, vol.9
-
-
Purewal, M.1
Velasco, M.2
Fretland, A.J.3
Hein, D.W.4
Wargovick, M.J.5
-
46
-
-
0029979636
-
Diet, acetylator phenotype, and risk of colorectal neoplasia
-
Roberts-Thomson, I. C., P. Ryan, K. K. Khoo, W. J. Hart, A. J. McMichael & R. N. Butler: Diet, acetylator phenotype, and risk of colorectal neoplasia. Lancet 1996, 347, 1372-1374.
-
(1996)
Lancet
, vol.347
, pp. 1372-1374
-
-
Roberts-Thomson, I.C.1
Ryan, P.2
Khoo, K.K.3
Hart, W.J.4
McMichael, A.J.5
Butler, R.N.6
-
47
-
-
0023011568
-
N-Acetyltransferase multiplicity and the bioactivation of N-arythydroxamic acids by hamster hepatic and intestinal enzymes
-
Smith, T. J. & P. E. Hanna: N-Acetyltransferase multiplicity and the bioactivation of N-arythydroxamic acids by hamster hepatic and intestinal enzymes. Carcinogenesis 1986, 7, 697-702.
-
(1986)
Carcinogenesis
, vol.7
, pp. 697-702
-
-
Smith, T.J.1
Hanna, P.E.2
-
48
-
-
0027337830
-
32P-Postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx-and PhIP-treated monkeys
-
32P-Postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx-and PhIP-treated monkeys. Carcinogenesis 1993, 14, 1389-1395.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1389-1395
-
-
Snyderwine, E.G.1
Davis, C.D.2
Nouso, K.3
Roller, P.P.4
Schut, H.A.J.5
-
49
-
-
0029586399
-
Unexpected antagonistic action of 3,2′-dimethyl-4-aminobiphenyl on aberrant crypt induction by 1,2-dimethylhydrazine or azoxymethane in rat colon
-
Steffensen, I.-L., J. E. Paulsen & J. Alexander: Unexpected antagonistic action of 3,2′-dimethyl-4-aminobiphenyl on aberrant crypt induction by 1,2-dimethylhydrazine or azoxymethane in rat colon. Carcinogenesis 1995, 16, 2981-2988.
-
(1995)
Carcinogenesis
, vol.16
, pp. 2981-2988
-
-
Steffensen, I.-L.1
Paulsen, J.E.2
Alexander, J.3
-
50
-
-
0031417627
-
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine increases the numbers of tumors, cystic crypts and aberrant crypt foci in multiple intestinal neoplasia mice
-
Steffensen, I.-L., J. E. Paulsen, T. J. Eide & J. Alexander: 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine increases the numbers of tumors, cystic crypts and aberrant crypt foci in multiple intestinal neoplasia mice. Carcinogenesis 1997, 18, 1049-1054.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1049-1054
-
-
Steffensen, I.-L.1
Paulsen, J.E.2
Eide, T.J.3
Alexander, J.4
-
51
-
-
0025963039
-
Induction of aberrant crypt foci in the large intestine of F344 rats by oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Takahashi, S., K. Ogawa, H. Ohshima, H. Esumi, N. Ito & T. Sugimura: Induction of aberrant crypt foci in the large intestine of F344 rats by oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Jap. J. Cancer Res. 1991, 82, 135-137.
-
(1991)
Jap. J. Cancer Res.
, vol.82
, pp. 135-137
-
-
Takahashi, S.1
Ogawa, K.2
Ohshima, H.3
Esumi, H.4
Ito, N.5
Sugimura, T.6
-
52
-
-
0021125918
-
Demonstration of carcinogenicity in F344 rats of 2-amino-3-methylimidazo[4,5-f]quinoline from broiled sardine, fried beef and beef extract
-
Takayama, S., Y. Nakatsuru, M. Masuda, H. Ohgaki, S. Sato & T. Sugimura: Demonstration of carcinogenicity in F344 rats of 2-amino-3-methylimidazo[4,5-f]quinoline from broiled sardine, fried beef and beef extract. Jap. J. Cancer Res. 1984, 75, 467-470.
-
(1984)
Jap. J. Cancer Res.
, vol.75
, pp. 467-470
-
-
Takayama, S.1
Nakatsuru, Y.2
Masuda, M.3
Ohgaki, H.4
Sato, S.5
Sugimura, T.6
-
53
-
-
0021881236
-
Multipotential carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in rats
-
Tanaka, T., W. S. Barnes, G. M. Williams & J. H. Weisburger: Multipotential carcinogenicity of the fried food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in rats. Jap. J. Cancer Res. 1985, 76, 570-576.
-
(1985)
Jap. J. Cancer Res.
, vol.76
, pp. 570-576
-
-
Tanaka, T.1
Barnes, W.S.2
Williams, G.M.3
Weisburger, J.H.4
-
54
-
-
0024555694
-
Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods
-
Tudek, B., R. P. Bird & W. R. Bruce: Foci of aberrant crypts in the colons of mice and rats exposed to carcinogens associated with foods. Cancer Res. 1989, 49, 1236-1240.
-
(1989)
Cancer Res.
, vol.49
, pp. 1236-1240
-
-
Tudek, B.1
Bird, R.P.2
Bruce, W.R.3
-
55
-
-
0001402395
-
Acetyltransferases
-
Eds.: I. G. Sipes, C. A. McQueen and A. J. Gandolfi. Elsevier Science Ltd., Oxford, UK
-
Vatsis, K. P. & W. W. Weber: Acetyltransferases. In: Comprehensive toxicology. Eds.: I. G. Sipes, C. A. McQueen and A. J. Gandolfi. Elsevier Science Ltd., Oxford, UK, 1997, pp. 385-399.
-
(1997)
Comprehensive Toxicology
, pp. 385-399
-
-
Vatsis, K.P.1
Weber, W.W.2
-
56
-
-
0030598397
-
Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat
-
Ware, J. A. & C. K. Svensson: Longitudinal distribution of arylamine N-acetyltransferases in the intestine of the hamster, mouse, and rat. Biochem. Pharmacol. 1996, 52, 1613-1620.
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 1613-1620
-
-
Ware, J.A.1
Svensson, C.K.2
-
57
-
-
0021813284
-
N-Acetylation pharmacogenetics
-
Weber, W. W. & D. W. Hein: N-Acetylation pharmacogenetics. Pharmacol. Rev. 1985, 37, 25-79.
-
(1985)
Pharmacol. Rev.
, vol.37
, pp. 25-79
-
-
Weber, W.W.1
Hein, D.W.2
-
58
-
-
0028013265
-
Genotoxicity and carcinogenicity in rats and mice of 2-amino-3,6-dihydro-3-methyl-7H-imidazolo[4,5-f]quinolin-7-one: An intestinal bacterial metabolite of 2-amino-3-methyl-3H-imidazo[4,5-f]-quinoline
-
Weisburger, J. H., A. Rivenson, J. Reinhardt, C. Aliaga, J. Braley, L. M. Dolan, G. M. Williams, E. Zang, D. G. I. Kingston, M. Bashir, Y.-Z. Shu, T. D. Wilkins & R. L. Van Tassell: Genotoxicity and carcinogenicity in rats and mice of 2-amino-3,6-dihydro-3-methyl-7H-imidazolo[4,5-f]quinolin-7-one: an intestinal bacterial metabolite of 2-amino-3-methyl-3H-imidazo[4,5-f]-quinoline. J. Natl. Cancer Inst. 1994, 86, 25-30.
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 25-30
-
-
Weisburger, J.H.1
Rivenson, A.2
Reinhardt, J.3
Aliaga, C.4
Braley, J.5
Dolan, L.M.6
Williams, G.M.7
Zang, E.8
Kingston, D.G.I.9
Bashir, M.10
Shu, Y.-Z.11
Wilkins, T.D.12
Van Tassell, R.L.13
-
59
-
-
0031428582
-
Relationship between acetylator status, smoking, diet and colorectal cancer risk in the north-east of England
-
Welfare, M. R., J. Cooper, M. F. Bassendine & A. K. Daly: Relationship between acetylator status, smoking, diet and colorectal cancer risk in the north-east of England. Carcinogenesis 1997, 18, 1351-1354.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1351-1354
-
-
Welfare, M.R.1
Cooper, J.2
Bassendine, M.F.3
Daly, A.K.4
-
60
-
-
0032934961
-
Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: Relevance to xenobiotic metabolism and toxicity
-
Wormhoudt, L. W., J. N. M Commandeur & N. P. E. Vermeulen: Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity. Crit. Rev. Toxicol. 1999, 29, 59-124.
-
(1999)
Crit. Rev. Toxicol.
, vol.29
, pp. 59-124
-
-
Wormhoudt, L.W.1
Commandeur, J.N.M.2
Vermeulen, N.P.E.3
-
61
-
-
0029900928
-
Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo4,5-fquinoline-induced DNA adducts and colonie aberrant crypts in the F344 rat
-
Xu, M., A. C. Bailey, J. F. Hernaez, C. R. Taoka, H. A. J. Schut & R. H. Dashwood: Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-f)quinoline-induced DNA adducts and colonie aberrant crypts in the F344 rat. Carcinogenesis 1996, 17, 1429-1434.
-
(1996)
Carcinogenesis
, vol.17
, pp. 1429-1434
-
-
Xu, M.1
Bailey, A.C.2
Hernaez, J.F.3
Taoka, C.R.4
Schut, H.A.J.5
Dashwood, R.H.6
|