-
1
-
-
0029896530
-
Role of leptin in the neuroendocrine response to fasting
-
Ahima, R. S., D. Prabakaran, C. Mantzoros, D. Qu, B. Lowell, E. Maratos-Flier, and J. S. Flier. Role of leptin in the neuroendocrine response to fasting. Nature 382: 250-252, 1996.
-
(1996)
Nature
, vol.382
, pp. 250-252
-
-
Ahima, R.S.1
Prabakaran, D.2
Mantzoros, C.3
Qu, D.4
Lowell, B.5
Maratos-Flier, E.6
Flier, J.S.7
-
3
-
-
0004270170
-
-
New York: John Wiley
-
Ausubel, F. M., M. Frederick, R. Bent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (Editors). Current Protocols in Molecular Biology. New York: John Wiley, 1994.
-
(1994)
Current Protocols in Molecular Biology
-
-
Ausubel, F.M.1
Frederick, M.2
Bent, R.3
Kingston, R.E.4
Moore, D.D.5
Seidman, J.G.6
Smith, J.A.7
Struhl, K.8
-
4
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
-
Bruning, J. C., J. Winnay, S. Bonner-Weir, S. I. Taylor, D. Accili, and C. R. Kahn. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell 88: 561-572, 1997.
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Bruning, J.C.1
Winnay, J.2
Bonner-Weir, S.3
Taylor, S.I.4
Accili, D.5
Kahn, C.R.6
-
5
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chehab, F. F., M. E. Lim, and R. Lu. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat. Genet. 12: 318-320, 1996.
-
(1996)
Nat. Genet.
, vol.12
, pp. 318-320
-
-
Chehab, F.F.1
Lim, M.E.2
Lu, R.3
-
6
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen, H., O. Charlat, L. A. Tartaglia, E. A. Woolf, X. Weng, S. J. Ellis, N. D. Lakey, J. Culpepper, K. J. Moore, R. E. Breitbart, G. M. Duyk, R. I. Tepper, and J. P. Morgenstern. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84: 491-495, 1996.
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
Moore, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
7
-
-
0031057818
-
Leptin is a metabolic gate for the onset of puberty in the female rat
-
Cheung, C. C., J. E. Thornton, J. L. Kuijjper, D. S. Weigle, D. K. Clifton, and R. A. Steiner. Leptin is a metabolic gate for the onset of puberty in the female rat. Endocrinology 138: 855-858, 1997.
-
(1997)
Endocrinology
, vol.138
, pp. 855-858
-
-
Cheung, C.C.1
Thornton, J.E.2
Kuijjper, J.L.3
Weigle, D.S.4
Clifton, D.K.5
Steiner, R.A.6
-
8
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
-
(1987)
Anal. Biochem.
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
9
-
-
9844247559
-
Monogenic models of obesity
-
Chua, S. C. Monogenic models of obesity. Behav. Genet. 27: 277-284, 1997.
-
(1997)
Behav. Genet.
, vol.27
, pp. 277-284
-
-
Chua, S.C.1
-
10
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fatty due to mutations in the ob (leptin) receptor
-
Chua, S. C., W. K. Chung, X. S. Wu-Peng, Y. Zhang, S. Liu, L. Tartaglia, and R. L. Leibel. Phenotypes of mouse diabetes and rat fatty due to mutations in the ob (leptin) receptor. Science 271: 994-996, 1996.
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua, S.C.1
Chung, W.K.2
Wu-Peng, X.S.3
Zhang, Y.4
Liu, S.5
Tartaglia, L.6
Leibel, R.L.7
-
11
-
-
0030685790
-
Fine structure of the murine leptin receptor gene: Splice site suppression is required to form two alternatively spliced transcripts
-
Chua, S. C., I. K. Koutras, L. Han, S. Liu, J. Kay, S. J. Young, W. K. Chung, and R. L. Leibel. Fine structure of the murine leptin receptor gene: splice site suppression is required to form two alternatively spliced transcripts. Genomics 45: 264-270, 1997.
-
(1997)
Genomics
, vol.45
, pp. 264-270
-
-
Chua, S.C.1
Koutras, I.K.2
Han, L.3
Liu, S.4
Kay, J.5
Young, S.J.6
Chung, W.K.7
Leibel, R.L.8
-
12
-
-
0015792424
-
Effects of parabiosis of obese with diabetes and normal mice
-
Coleman, D. L. Effects of parabiosis of obese with diabetes and normal mice. Diabetologia 9: 294-298, 1973.
-
(1973)
Diabetologia
, vol.9
, pp. 294-298
-
-
Coleman, D.L.1
-
13
-
-
0018139377
-
Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
-
Coleman, D. L. Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14: 141-148, 1978.
-
(1978)
Diabetologia
, vol.14
, pp. 141-148
-
-
Coleman, D.L.1
-
14
-
-
0016289615
-
Hyperinsulinemia in pre-weaning diabetes (db) mice
-
Coleman, D. L., and K. P. Hummel. Hyperinsulinemia in pre-weaning diabetes (db) mice. Diabetologia 10: 607-610, 1974.
-
(1974)
Diabetologia
, vol.10
, pp. 607-610
-
-
Coleman, D.L.1
Hummel, K.P.2
-
15
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas, J. L., K. S. Gajiwala, M. Maffei, S. L. Cohen, B. T. Chait, D. Rabinowitz, R. L. Lallone, S. K. Burley, and J. M. Friedman. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269: 543-546, 1995.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
Rabinowitz, D.6
Lallone, R.L.7
Burley, S.K.8
Friedman, J.M.9
-
16
-
-
0029957181
-
Real time quantitative PCR
-
Heid, C. A., J. Stevens, K. J. Livak, and P. M. Williams. Real time quantitative PCR. Genome Res. 6: 986-994, 1996.
-
(1996)
Genome Res.
, vol.6
, pp. 986-994
-
-
Heid, C.A.1
Stevens, J.2
Livak, K.J.3
Williams, P.M.4
-
17
-
-
0029847504
-
Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein
-
Hotamisligil, G. S., R. S. Johnson, R. J. Distel, R. Ellis, V. E. Papaioannou, and B. M. Spiegelman. Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein. Science 274: 1377-1379, 1996.
-
(1996)
Science
, vol.274
, pp. 1377-1379
-
-
Hotamisligil, G.S.1
Johnson, R.S.2
Distel, R.J.3
Ellis, R.4
Papaioannou, V.E.5
Spiegelman, B.M.6
-
18
-
-
0014004384
-
Diabetes, a new mutation in the mouse
-
Hummel, K. P., M. M. Dickie, and D. L. Coleman. Diabetes, a new mutation in the mouse. Science 153: 1127-1128, 1966.
-
(1966)
Science
, vol.153
, pp. 1127-1128
-
-
Hummel, K.P.1
Dickie, M.M.2
Coleman, D.L.3
-
19
-
-
0025079312
-
Quantitation of HIV-1 proviral DNA relative to cellular DNA by the polymerase chain reaction
-
Kellogg, D. E., J. J. Sninsky, and S. Kowk. Quantitation of HIV-1 proviral DNA relative to cellular DNA by the polymerase chain reaction. Anal. Biochem. 189: 202-208, 1990.
-
(1990)
Anal. Biochem.
, vol.189
, pp. 202-208
-
-
Kellogg, D.E.1
Sninsky, J.J.2
Kowk, S.3
-
20
-
-
0031436635
-
The molecular genetics of rodent single gene obesities
-
Leibel, R. L., W. K. Chung, and S. C. Chua. The molecular genetics of rodent single gene obesities. J. Biol. Chem. 272: 31937-31940, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31937-31940
-
-
Leibel, R.L.1
Chung, W.K.2
Chua, S.C.3
-
21
-
-
0019760290
-
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse IV. Male lethal syndrome in CBA/Lt mice
-
Leiter, E. H. The influence of genetic background on the expression of mutations at the diabetes locus in the mouse IV. Male lethal syndrome in CBA/Lt mice. Diabetes 30: 1035-1044, 1981.
-
(1981)
Diabetes
, vol.30
, pp. 1035-1044
-
-
Leiter, E.H.1
-
22
-
-
0019037039
-
3J) at the diabetes locus in strain 129/J mice. I. Physiological and histological characterization
-
3J) at the diabetes locus in strain 129/J mice. I. Physiological and histological characterization. Diabetologia 19: 58-65, 1980.
-
(1980)
Diabetologia
, vol.19
, pp. 58-65
-
-
Leiter, E.H.1
Coleman, D.L.2
Eisenstein, A.B.3
Strack, I.4
-
23
-
-
0019749949
-
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse
-
Leiter, E. H., D. L. Coleman, and K. P. Hummel. The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. Diabetes 30: 1029-1035, 1981.
-
(1981)
Diabetes
, vol.30
, pp. 1029-1035
-
-
Leiter, E.H.1
Coleman, D.L.2
Hummel, K.P.3
-
24
-
-
0014502857
-
The so-called Swiss mouse
-
Lynch, C. The so-called Swiss mouse. Lab. Anim. Care 19: 214-220, 1969.
-
(1969)
Lab. Anim. Care
, vol.19
, pp. 214-220
-
-
Lynch, C.1
-
25
-
-
0029240503
-
Genomic analysis of the C57BL/Ks mouse strain
-
Naggert, J. K., J. L. Mu, W. Frankel, D. W. Bailey, and B. Paigen. Genomic analysis of the C57BL/Ks mouse strain. Mamm. Genome 6: 131-133, 1995.
-
(1995)
Mamm. Genome
, vol.6
, pp. 131-133
-
-
Naggert, J.K.1
Mu, J.L.2
Frankel, W.3
Bailey, D.W.4
Paigen, B.5
-
26
-
-
0025008853
-
High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients
-
Pang, S., Y. Koyanage, S. Miles, C. Wiley, H. V. Vinters, and I. S. Chen. High levels of unintegrated HIV-1 DNA in brain tissue of AIDS dementia patients. Nature 343: 85-89, 1990.
-
(1990)
Nature
, vol.343
, pp. 85-89
-
-
Pang, S.1
Koyanage, Y.2
Miles, S.3
Wiley, C.4
Vinters, H.V.5
Chen, I.S.6
-
27
-
-
0022483765
-
Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice
-
Prochazka, M., F. H. Premdas, E. H. Leiter, and L. G. Lipson. Estrone treatment dissociates primary versus secondary consequences of "diabetes" (db) gene expression in mice. Diabetes 35: 725-728, 1986.
-
(1986)
Diabetes
, vol.35
, pp. 725-728
-
-
Prochazka, M.1
Premdas, F.H.2
Leiter, E.H.3
Lipson, L.G.4
-
28
-
-
0027449212
-
Quantitative PCR: Theoretical considerations with practical applications
-
Raeymaekers, L. Quantitative PCR: theoretical considerations with practical applications. Anal. Biochem. 214: 582-585, 1993.
-
(1993)
Anal. Biochem.
, vol.214
, pp. 582-585
-
-
Raeymaekers, L.1
-
29
-
-
0018908453
-
Genetic variance of laboratory outbred Swiss mice
-
Rice, M. C., and S. J. O'Brien. Genetic variance of laboratory outbred Swiss mice. Nature 283: 157-161, 1980.
-
(1980)
Nature
, vol.283
, pp. 157-161
-
-
Rice, M.C.1
O'Brien, S.J.2
-
30
-
-
13344280346
-
Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice
-
Schwartz, M. W., D. G. Baskin, T. R. Bukowski, J. L. Kuijper, D. Foster, G. Lasser, D. E., Prunkard, D. Porte, S. C. Woods, R. J. Seeley, and D. S. Weigle. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 45: 531-535, 1996.
-
(1996)
Diabetes
, vol.45
, pp. 531-535
-
-
Schwartz, M.W.1
Baskin, D.G.2
Bukowski, T.R.3
Kuijper, J.L.4
Foster, D.5
Lasser, G.6
Prunkard, D.E.7
Porte, D.8
Woods, S.C.9
Seeley, R.J.10
Weigle, D.S.11
-
31
-
-
0029098589
-
The role of neuropeptide Y in the antiobesity action of the obese gene product
-
Stephens, T. W., M. Basinski, P. K. Bristow, J. M. Bue-Valleskey, S. G. Burgett, L. Craft, J. Hale, J. Hoffmann, H. M. Hsiung, A. Kriauciunas, W. Mackellar, P. R. Rosteck, B. Schoner, D. Smith, F. C. Tinsley, X. Y. Zhang, and M. Heiman. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377: 530-532, 1995.
-
(1995)
Nature
, vol.377
, pp. 530-532
-
-
Stephens, T.W.1
Basinski, M.2
Bristow, P.K.3
Bue-Valleskey, J.M.4
Burgett, S.G.5
Craft, L.6
Hale, J.7
Hoffmann, J.8
Hsiung, H.M.9
Kriauciunas, A.10
Mackellar, W.11
Rosteck, P.R.12
Schoner, B.13
Smith, D.14
Tinsley, F.C.15
Zhang, X.Y.16
Heiman, M.17
-
32
-
-
0025887329
-
Rat obesity gene fatty (fa) maps to chromosome 5: Evidence for homology with the mouse gene diabetes (db)
-
Truett, G., N. Bahary, J. M. Friedman, and R. L. Leibel. Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db). Proc. Natl. Acad. Sci. USA 88: 7806-7809, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 7806-7809
-
-
Truett, G.1
Bahary, N.2
Friedman, J.M.3
Leibel, R.L.4
-
33
-
-
85050956429
-
Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats
-
Vettor, R., N. Zarjevski, I. Cusin, F. Rohner-Jeanrenaud, and B. Jeanrenaud. Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats. Diabetologia 37: 1202-1208, 1994.
-
(1994)
Diabetologia
, vol.37
, pp. 1202-1208
-
-
Vettor, R.1
Zarjevski, N.2
Cusin, I.3
Rohner-Jeanrenaud, F.4
Jeanrenaud, B.5
-
34
-
-
0033562350
-
Development and validation of real-time quantitative reverse transcriptase polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro
-
Winer, J., C. K. S. Jung, I. Shackel, and P. M. Williams. Development and validation of real-time quantitative reverse transcriptase polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal. Biochem. 270: 41-49, 1999.
-
(1999)
Anal. Biochem.
, vol.270
, pp. 41-49
-
-
Winer, J.1
Jung, C.K.S.2
Shackel, I.3
Williams, P.M.4
-
35
-
-
0031046730
-
Phenotype of the obese Koletsky (f) rat due to Typ763Stop mutation in the extracellular domain of the leptin receptor (Lepr): Evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat
-
Wu-Peng, X. S., S. C. Chua, N. Okada, S. Liu, M. Nicolson, and R. L. Leibel. Phenotype of the obese Koletsky (f) rat due to Typ763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat. Diabetes 46: 513-518, 1997.
-
(1997)
Diabetes
, vol.46
, pp. 513-518
-
-
Wu-Peng, X.S.1
Chua, S.C.2
Okada, N.3
Liu, S.4
Nicolson, M.5
Leibel, R.L.6
-
36
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y., R. Proenca, M. Maffei, M. Barone, L. Leopold, and J. M. Friedman. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432, 1994.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
|