Essential roles of carbohydrate signals in development, immune response and tissue functions, as revealed by gene targeting

Journal of Biochemistry

Volumn 127, Issue 2, 2000, Pages 171-176

  Muramatsu, Takashi ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Glycolipids; Glycoproteins; Glycosyltransferases; Proteoglycans; Sulfotransferase s

Indexed keywords

CARBOHYDRATE; CERAMIDE GLUCOSYLTRANSFERASE; GANGLIOSIDE GD2; GANGLIOSIDE GM2; GLYCOLIPID; GLYCOPROTEIN; GLYCOSYLTRANSFERASE; HEPARAN SULFATE; N ACETYLGLUCOSAMINYLTRANSFERASE; PROTEOGLYCAN; SULFOTRANSFERASE;

ANTIBODY PRODUCTION; CARBOHYDRATE ANALYSIS; EMBRYO DEVELOPMENT; ENZYME DEFICIENCY; GENE TARGETING; IMMUNE RESPONSE; KNOCKOUT MOUSE; MALE STERILITY; MOUSE; NONHUMAN; REVIEW;

EID: 0034092856     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022590     Document Type: Review

References (43)

1. Metzler, M., Gertz, A., Sarkar, M., Schachter, H., Schrader, J.W., and Marth, J.D. (1994) Complex asparagine-linked oligosaccharides are required for morphogenic events during post-implantation development. EMBO J. 13, 2056-2065
2. Ioffe, E. and Stanley, P. (1994) Mice lacking N-acetylglucosaminyltransferase I activity die at mid-gestation, revealing an essential role for complex or hybrid N-linked carbohydrates. Proc. Natl. Acad. Sci. USA 91, 728-732
3. Muramatsu, T. (1988) Developmentally regulated expression of cell surface carbohydrates during mouse embryogenesis. J. Cell. Biochem. 36, 1-14
4. Campbell, R.M., Metzler, M., Granovsky, M., Dennis, J.W., and Marth, J.D. (1995) Complex asparagine-linked oligosaccharides in Mgat I-null embryos. Glycobiology 5, 535-543
5. Ioffe, E., Liu, Y., and Stanley, P. (1997) Complex N-glycans in Mgat I null preimplantation embryos arise from maternal Mgat I RNA. Glycobiology 7, 913-919
6. Chui, D., Oh-Eda, M., Liao, Y-F., Panneerselvam, K., Lal, A., Marek, K.W., Freeze, H.H., Moremen, K.W., Fukuda, M.N., and Marth, J.D. (1997) Alpha-mannosidase-II deficiency results in dyserythropoiesis and unveils an alternate pathway in oligosaccharide biosynthesis. Cell 90, 157-167
7. Marek, K.W., Vijay, I.K., and Marth, J.D. (1999) A recessive deletion in the GlcNAc-1-phosphotransferase gene results in peri-implantation embryonic lethality. Glycobiology, in press.
8. Lu, Q., Hasty, P., and Shur, B.D. (1997) Targeted mutation in β1,4-galactosyltransferase leads to pituitary insufficiency and neonatal lethality. Dev. Biol. 181, 257-267
9. Asano, M., Furukawa, K., Kido, M., Matsumoto, S., Umesaki, Y., Kochibe, N., and Iwakura, Y. (1997) Growth retardation and early death of β1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells. EMBO J. 16, 1850-1857
10. Kido, M., Asano, M., Iwakura, Y., Ichinose, M., Miki, K., and Furukawa, K. (1998) Presence of polysialic acid and HNK-1 carbohydrate on brain glycoproteins from β-1,4-galactosyltransferase-knockout mice. Biochem. Biophys. Res. Commun. 245, 860-864
11. Sato, T., Furukawa, K., Bakker, H., Van den Eijnden, D.H., and Van Die, I. (1998) Molecular cloning of a human cDNA encoding β-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc β-1,4-galactosyltransferase. Proc. Natl. Acad. Sci. USA 95, 472-477
12. Lu, Q. and Shur, B.D. (1997) Sperm from β1,4-galactosyltransferase-null mice are refractory to ZP3-induced acrosome reactions and penetrate the zona pellucida poorly. Development 124, 4121-4131
13. Thall, A.D., Maly, P., and Lowe, J.B. (1995) Oocyte Galα1,3Gal epitopes implicated in sperm adhesion to the zona pellucida glycoprotein ZP3 are not required for fertilization in the mouse. J. Biol. Chem. 270, 21437-21440
14. Tearle, R.G., Tange, M.J., Zannettino, Z.L., Katerelos, M., Shinkel, T.A., Van Denderen, B.J.W., Lonie, A.J., Lyons, I., Nottle, M.B., Cox, T., Becker, C., Peura, A.M., Wigley, P.L., Crawford, R.J., Robbins, A.J., Pearse, M.J., and D'Apice, A.J.F. (1996) The α1,3galactosyltransferase knockout mouse. Transplantation 61, 13-19
15. Van Denderen, B.J.W., Salvaris, E., Romanella, M., Aminian, A., Katerelos, M., Tange, M.J., Pearse, M.J., and D'Apice, A. J.F. (1997) Combination of decay-accelerating factor expression and α1,3galactosyltransferase knockout affords added protection from human complement-mediated injury. Transplantation 64, 882-888
16. Yamashita, T., Wada, R., Sasaki, T., Deng, C., Bierfreund, U., Sandhoff, K., and Proia, R.L. (1999) A vital role for glycosphingolipid synthesis during development and differentiation. Proc. Natl. Acad. Sci. USA 96, 9142-9147
17. Takamiya, K., Yamamoto, A., Furukawa, K., Yamashiro, S., Shin, M., Okada, M., Fukumoto, S., Haraguchi, M., Takeda, N., Fujimura, K., Sakae, M., Kishikawa, M., Shiku, H., Furukawa, K., and Aizawa, S. (1996) Mice with disrupted GM2/GD2 synthase gene lack complex gangliosides but exhibit only subtle defects in their nervous system. Proc. Natl. Acad. Sci. USA 93, 10662-10667
18. Takamiya, K., Yamamoto, A., Furukawa, K., Zhao, J., Fukumoto, S., Yamashiro, S., Okada, M., Haraguchi, M., Shin, M., Kishikawa, M., Shiku, H., Aizawa, S., and Furukawa, K. (1998) Complex gangliosides are essential in spermatogenesis of mice: possible roles in the transport of testosterone. Proc. Natl. Acad. Sci. USA 95, 12147-12152
19. Kobayashi, M., Habuchi, H., Yoneda, M., Habuchi, O., and Kimata, K. (1997) Molecular cloning and expression of Chinese hamster ovary cell heparan sulfate 2-sulfotransferase. J. Biol. Chem. 272, 13980-13985
20. Bullock, S.L., Fletcher, J.M., Beddington, R.S.P., and Wilson, V.A. (1998) Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 12, 1894-1906
21. Nakato, T., Futch, A., and Selleck, S.B. (1995) The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila. Development 121, 3687-3702
22. Haerry, T.E., Heslip, T.R., Marsh, J.L., and O'Connor, M.B. (1997) Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development 124, 3055-3064
23. Arikawa-Hirasawa, E., Watanabe, H., Takami, H., Hassell, J. R., and Yamada, Y. (1999) Perlecan is essential for cartilage and cephalic development. Nat. Genet. 23, 354-358
24. Spicer, A.P., Camenish, T., Nguyan, T., Haudenschild, D., and McDonald, J. (1999) Hyaluronan biosynthesis and function in vertebrates. Glycoconjugate J. 16, S5
25. Schmits, R., Filmus, J., Gerwin, N., Senaldi, G., Kiefer, F., Kundig, T., Wakeham, A., Shahinian, A., Catzavelos, C., Rak, J., Furlonger, C., Zakarian, A., Simard, J.J.L., Ohashi, P.S., Paige, C.J., Gutierrez-Ramos, J.C., and Mak, T.W. (1997) CD44 regulates hematopoietic progenitor distribution, granuloma formation and tumorigenicity. Blood 90, 2217-2233
26. Kansas, G.S. (1996) Selectins and their ligands: current concepts and controversies. Blood 88, 3259-3287
27. Imai, Y., Lasky, L.A., and Rosen, S.D. (1993) Sulfation requirement for GlyCAM-1, an endothelial ligand for L-selectin. Nature 361, 555-557
28. Kimura, N., Mitsuoka, C., Kanamori, A., Hiraiwa, N., Uchimura, K., Muramatsu, T., Tamatani, T., Kansas, G., and Kannagi, R. (1999) Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of α1-3 fucosyltransferase VII and newly cloned GlcNAc β:6-sulfotransferase cDNA. Proc. Natl. Acad. Sci. USA 96, 4530-4539
29. Maly, P., Thall, A.D., Petryniak, B., Rogers, C.E., Smith, P.L., Marks, R.M., Kelly, R.J., Gersten, K.M., Cheng, G., Saunders, T.L., Camper, S.A., Camphausen, R.T., Sullivan, F.X., Isogai, Y., Hindsgaul, O., von Andrian, U.H., and Lowe, J.B. (1996) The α(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell 86, 643-653
30. Ellies, L.G., Tsuboi, S., Petryniak, B., Lowe, J.B., Fukuda, M., and Marth, J.D. (1998) Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation. Immunity 9, 881-890
31. Hennet, T., Chui, D., Paulson, J.C., and Marth, J.D. (1998) Immune regulation by the ST6 Gal sialyltransferase. Proc. Natl. Acad. Sci. USA 95, 4504-4509
32. Sato, S., Miller, A.S., Inaoki, M., Bock, C.B., Jansen, P.J., Tang, M.L.K., and Tedder, T.F. (1996) CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5, 551-562
33. Otipoby, K.L., Andersson, K.B., Draves, K.E., Klaus, S.J., Farr, A.G., Kerner, J.D., Perlmutter, R.M., Law, C.-L., and Clark, E.A. (1996) CD22 regulates thymus-independent responses and the lifespan of B cells. Nature 384, 634-637
34. O'Keefe, T.L., Williams, G.T., Davies, S.L., and Neuberger, M.S. (1996) Hypersensitive B cells in CD22-deficient mice. Science 274, 798-801
35. Zhao, J., Furukawa, K., Fukumoto, S., Okada, M., Furugen, R., Miyazaki, H., Takamiya, K., Aizawa, S., Shiku, H., Matsuyama, T., and Furukawa, K. (1999) Attenuation of interleukin 2 signal in the spleen cells of complex ganglioside-lacking mice. J. Biol. Chem. 274, 13744-13747
36. Ellies, L.G., Chui, D., Priatel, J.J., and Marth, J.D. (1999) Sialyltransferase function in immune regulation. Glycoconjugate J. 16, S6
37. Furukawa, K., Fukumoto, S., Mutoh, T., Ito, M., Oishi, H., Furukawa, K., Mitsuda, T., Okajima, T., Honda, T., and Sugiura, Y. (1999) Roles of glycosphingolipids in the nervous system: studies by the remodeling of carbohydrate moiety in cultured cells and in experimental animals. Glycoconjugate J. 16, S57
38. Sheikh, K.A., Sun, J., Liu, Y., Kawai, H., Crawford, T.O., Proia, R.L., Griffin, J.W., and Schnaar, R.L. (1999) Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Glycoconjugate J. 16, S58
39. Coetzee, T., Fujita, N., Dupree, J., Shi, R., Blight, A., Suzuki, K., Suzuki, K., and Popko, B. (1996) Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Cell 86, 209-219
40. Humphries, D.E., Wong, G.W., Friend, D.S., Gurish, M.F., Qiu, W.T., Huang, C., Sharpe, A.H., and Stevens, R.L. (1999) Heparin is essential for the storage of specific granule proteases in mast cells. Nature 400, 769-772
41. Forsberg, E., Pejler, G., Ringvall, M., Lunderius, C., Tomasini-Johansson, B., Kusche-Gullberg, M., Eriksson, I., Ledin, J., Hellman, L., and Kjellén, L. (1999) Abnormal mast cells in mice deficient in a haparin-synthesizing enzyme. Nature 400, 773-776
42. Xu, T., Bianco, P., Fisher, L.W., Longenecker, G., Smith, E., Goldstein, S., Bonadio, J., Boskey, A., Heegaard, A-M., Sommer, B., Satomura, K., Dominguez, P., Zhao, C., Kulkarni, A.B., Robey, P.G., and Young, M.F. (1998) Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat. Genet. 20, 78-81
43. Danielson, KG., Baribault, H., Holmes, D.F., Graham, H., Kadler, K.E., and Iozzo, R.V. (1997) Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility. J. Cell Biol. 136, 729-743