Overnutrition in spiny mice (Acomys cahirinus): β-cell expansion leading to rupture and overt diabetes on fat-rich diet and protective energy-wasting elevation in thyroid hormone on sucrose-rich diet

Diabetes/Metabolism Research and Reviews

Volumn 16, Issue 2, 2000, Pages 94-105

  Shafrir, Eleazar ^a  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Beta cell proliferation; Fat rich diet; Hepatic lipogenesis; Islet cell disruption; Islet insulin content; Nutritional diabetes; Spiny mice; Sucrose rich diet; T3 effects; T3 elevation

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); GLYCEROL 3 PHOSPHATE DEHYDROGENASE; INSULIN; LIOTHYRONINE; LIVER ENZYME; MITOCHONDRIAL ENZYME; THYROID HORMONE; THYROXINE; VERY LOW DENSITY LIPOPROTEIN;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; CELL HYPERPLASIA; CONTROLLED STUDY; DIABETES MELLITUS; ENERGY METABOLISM; ENZYME ACTIVITY; FAT INTAKE; FRUCTOSE METABOLISM; GLUCOSE INTOLERANCE; GLUCOSURIA; HEPATOMEGALY; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPERTROPHY; INSULIN RELEASE; KETOACIDOSIS; LIOTHYRONINE BLOOD LEVEL; LIPOGENESIS; LIVER LEVEL; LIVER METABOLISM; MOUSE; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SUGAR INTAKE; THERMOGENESIS; THYROXINE BLOOD LEVEL; TISSUE GROWTH; WEIGHT GAIN;

ADIPOSE TISSUE; ANIMALS; BODY TEMPERATURE; DIABETES MELLITUS; DIETARY FATS; DIETARY SUCROSE; FEEDING BEHAVIOR; HEPATOMEGALY; HYPERPLASIA; IODIDE PEROXIDASE; ISLETS OF LANGERHANS; ISRAEL; LIVER; MITOCHONDRIA, LIVER; MURIDAE; OBESITY; PANCREATIC DISEASES; RUPTURE, SPONTANEOUS; TRIIODOTHYRONINE; WEIGHT GAIN;

EID: 0034089747     PISSN: 15207552     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1520-7560(200003/04)16:2<94::AID-DMRR82>3.0.CO;2-U     Document Type: Article

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