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Volumn 11, Issue 2, 2000, Pages 149-153

Transgenic animals with altered high-density lipoprotein composition and functions

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN A2; APOLIPOPROTEIN B; CARRIER PROTEIN; HIGH DENSITY LIPOPROTEIN; LIPOPROTEIN LIPASE; LIVER TRIACYLGLYCEROL LIPASE;

EID: 0034089183     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041433-200004000-00007     Document Type: Review
Times cited : (17)

References (54)
  • 1
    • 0016433018 scopus 로고
    • Plasma HDL concentration and development of ischaemic heart disease
    • 1 Miller GJ, Miller NE. Plasma HDL concentration and development of ischaemic heart disease. Lancet 1975; 1:16-19.
    • (1975) Lancet , vol.1 , pp. 16-19
    • Miller, G.J.1    Miller, N.E.2
  • 3
    • 0028887870 scopus 로고
    • Molecular physiology of reverse cholesterol transport
    • 3 Fielding CJ, Fielding PE. Molecular physiology of reverse cholesterol transport. J Lipid Res 1995; 36:211-228.
    • (1995) J Lipid Res , vol.36 , pp. 211-228
    • Fielding, C.J.1    Fielding, P.E.2
  • 4
    • 0030057184 scopus 로고    scopus 로고
    • HDL and lipoprotein oxidation
    • 4 Banka CL. HDL and lipoprotein oxidation. Curr Opin Lipidol 1996; 7:139-142.
    • (1996) Curr Opin Lipidol , vol.7 , pp. 139-142
    • Banka, C.L.1
  • 5
    • 0032813808 scopus 로고    scopus 로고
    • Mutations in ABC1 in Tangier disease and familial HDL deficiency
    • 5 Brooks-Wilson A, Marcil M, Clee SM, Zhang L-H, Roomp K, van Dam M, et al. Mutations in ABC1 in Tangier disease and familial HDL deficiency. Nat Gene 1999; 22:336-345. The identification of the molecular defect in Tangier disease is a major breakthrough for the elucidation of HDL formation.
    • (1999) Nat Gene , vol.22 , pp. 336-345
    • Brooks-Wilson, A.1    Marcil, M.2    Clee, S.M.3    Zhang, L.-H.4    Roomp, K.5    Van Dam, M.6
  • 6
    • 0032813809 scopus 로고    scopus 로고
    • The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease
    • 6 Bodzioch M, Orso E, Klucken J, Langmann T, Böttcher A, Diederich W, et al. The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat Genet 1999; 22:347-351. The identification of the molecular defect in Tangier disease is a major breakthrough for the elucidation of HDL formation.
    • (1999) Nat Genet , vol.22 , pp. 347-351
    • Bodzioch, M.1    Orso, E.2    Klucken, J.3    Langmann, T.4    Böttcher, A.5    Diederich, W.6
  • 7
    • 0032813660 scopus 로고    scopus 로고
    • Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
    • 7 Rust S, Rosier M, Funke H, Real J, Amoura Z, Piette J-C, et al. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1. Nat Genet 1999; 22:352-355. The identification of the molecular defect in Tangier disease is a major breakthrough for the elucidation of HDL formation.
    • (1999) Nat Genet , vol.22 , pp. 352-355
    • Rust, S.1    Rosier, M.2    Funke, H.3    Real, J.4    Amoura, Z.5    Piette, J.-C.6
  • 8
    • 0033559827 scopus 로고    scopus 로고
    • Targeted mutation of plasma PLTP gene markedly reduces HDL levels
    • 8 Jiang XC, Bruce C, Mar J, Lin M, Ji Y, Francone OL, Tall AR. Targeted mutation of plasma PLTP gene markedly reduces HDL levels. J Clin Invest 1999; 103:907-914. This is an excellent study establishing the essential role of PLTP in the transfer of VLDL surface lipids to HDL.
    • (1999) J Clin Invest , vol.103 , pp. 907-914
    • Jiang, X.C.1    Bruce, C.2    Mar, J.3    Lin, M.4    Ji, Y.5    Francone, O.L.6    Tall, A.R.7
  • 10
    • 0033021140 scopus 로고    scopus 로고
    • Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and HDL-cholesterol levels
    • 10 Levak-Frank S, Hofmann W, Weinstock PH, Radner H, Sattler W, Breslow JL, Zechner R. Induced mutant mouse lines that express lipoprotein lipase in cardiac muscle, but not in skeletal muscle and adipose tissue, have normal plasma triglyceride and HDL-cholesterol levels. Proc Natl Acad Sci USA 1999; 96:3165-3170. In this study the expression of LPL in cardiac muscle only was sufficient to normalize VLDL catabolism.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3165-3170
    • Levak-Frank, S.1    Hofmann, W.2    Weinstock, P.H.3    Radner, H.4    Sattler, W.5    Breslow, J.L.6    Zechner, R.7
  • 11
    • 0027296725 scopus 로고
    • Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia
    • 11 Shimada M, Shimano H, Gotoda K, Yamamoto K, Kawamura M, Inaba T, et al. Overexpression of human lipoprotein lipase in transgenic mice. Resistance to diet-induced hypertriglyceridemia and hypercholesterolemia. J Biol Chem 1993; 268:17924-17929.
    • (1993) J Biol Chem , vol.268 , pp. 17924-17929
    • Shimada, M.1    Shimano, H.2    Gotoda, K.3    Yamamoto, K.4    Kawamura, M.5    Inaba, T.6
  • 13
    • 0029658538 scopus 로고    scopus 로고
    • Increased preβ-HDL, apolipoprotein A-I and phospholipid in mice expressing the human PLTP and human apo A-I transgenes
    • 13 Jiang X, Francone OL, Bruce C, Millne R, Mar J, Walsh A, et al. Increased preβ-HDL, apolipoprotein A-I and phospholipid in mice expressing the human PLTP and human apo A-I transgenes. J Clin Invest 1996; 98:2373-2380.
    • (1996) J Clin Invest , vol.98 , pp. 2373-2380
    • Jiang, X.1    Francone, O.L.2    Bruce, C.3    Millne, R.4    Mar, J.5    Walsh, A.6
  • 14
    • 0037577517 scopus 로고    scopus 로고
    • Plasma phospholipid transfer protein. Adenovirus-mediated overexpression in mice leads to decreased plasma HDL and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL
    • 14 Föger B, Santamarina-Fojo S, Shamburek RD, Parrot CL, Talley GD, Brewer Jr HB. Plasma phospholipid transfer protein. Adenovirus-mediated overexpression in mice leads to decreased plasma HDL and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL. J Biol Chem 1997; 272:27393-27400.
    • (1997) J Biol Chem , vol.272 , pp. 27393-27400
    • Föger, B.1    Santamarina-Fojo, S.2    Shamburek, R.D.3    Parrot, C.L.4    Talley, G.D.5    Brewer H.B., Jr.6
  • 16
    • 0344429365 scopus 로고    scopus 로고
    • High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing LCAT
    • 16 Berard AM, Remaley AT, Vaisman BL, Paigen B, Hoyt RF, Meyn SM, et al. High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing LCAT. Nat Med 1997; 3:744-749.
    • (1997) Nat Med , vol.3 , pp. 744-749
    • Berard, A.M.1    Remaley, A.T.2    Vaisman, B.L.3    Paigen, B.4    Hoyt, R.F.5    Meyn, S.M.6
  • 19
    • 0033585115 scopus 로고    scopus 로고
    • Hepatic scavenger receptor BI promotes rapid clearance of HDL free cholesterol and its transport into bile
    • 19 Ji Y, Wang N, Ramakrishnan R, Sehayek E, Huszar D, Breslow JL, Tall AR. Hepatic scavenger receptor BI promotes rapid clearance of HDL free cholesterol and its transport into bile. J Biol Chem 1999; 274:33398-33402.
    • (1999) J Biol Chem , vol.274 , pp. 33398-33402
    • Ji, Y.1    Wang, N.2    Ramakrishnan, R.3    Sehayek, E.4    Huszar, D.5    Breslow, J.L.6    Tall, A.R.7
  • 20
    • 0032797071 scopus 로고    scopus 로고
    • Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL by cells expressing scavenger receptor BI
    • 20 Collet X, Tall AR, Serajuddin H, Guendouzi K, Royer L, Oliveira H, et al. Remodeling of HDL by CETP in vivo and by CETP and hepatic lipase in vitro results in enhanced uptake of HDL by cells expressing scavenger receptor BI. J Lipid Res 1999; 40:1185-1193. The remodelling of HDL by the synergistic actions of CETP and hepatic lipase enhances selective HDL-cholesteryl ester uptake by SR-BI.
    • (1999) J Lipid Res , vol.40 , pp. 1185-1193
    • Collet, X.1    Tall, A.R.2    Serajuddin, H.3    Guendouzi, K.4    Royer, L.5    Oliveira, H.6
  • 22
    • 0032800282 scopus 로고    scopus 로고
    • Hepatic lipase promotes the selective uptake of HDL-cholesteryl esters via the scavenger receptor BI
    • 22 Lambert G, Chase MB, Bensadoun A, Brewer Jr HB, Santamarina-Fojo S. Hepatic lipase promotes the selective uptake of HDL-cholesteryl esters via the scavenger receptor BI. J Lipid Res 1999; 40:1294-1303. A convincing demonstration that hepatic lipase promotes selective uptake of HDL-cholesteryl esters by SR-BI by both its lipolytic and its ligand role.
    • (1999) J Lipid Res , vol.40 , pp. 1294-1303
    • Lambert, G.1    Chase, M.B.2    Bensadoun, A.3    Brewer H.B., Jr.4    Santamarina-Fojo, S.5
  • 24
    • 0032484117 scopus 로고    scopus 로고
    • Liver-specific overexpression of SR-BI decreases levels of VLDL apoB, LDL apoB, and HDL in transgenic mice
    • 24 Wang N, Arai T, Ji Y, Rinninger F, Tall AR. Liver-specific overexpression of SR-BI decreases levels of VLDL apoB, LDL apoB, and HDL in transgenic mice. J Biol Chem 1998; 273:32920-32926. The role of SR-BI in vivo is extended to the lowering of apo B-containing lipoproteins.
    • (1998) J Biol Chem , vol.273 , pp. 32920-32926
    • Wang, N.1    Arai, T.2    Ji, Y.3    Rinninger, F.4    Tall, A.R.5
  • 25
    • 0033548442 scopus 로고    scopus 로고
    • Lower plasma levels and accelerated clearance of HDL and non-HDL cholesterol in SR-BI transgenic mice
    • 25 Ueda Y, Ryer L, Gong E, Zhang J, Cooper PN, Francone O, Rubin EM. Lower plasma levels and accelerated clearance of HDL and non-HDL cholesterol in SR-BI transgenic mice. J Biol Chem 1999; 274:7165-7171. In this study increased hepatic expression of SR-BI accelerates the catabolism of HDL and non-HDL lipoproteins.
    • (1999) J Biol Chem , vol.274 , pp. 7165-7171
    • Ueda, Y.1    Ryer, L.2    Gong, E.3    Zhang, J.4    Cooper, P.N.5    Francone, O.6    Rubin, E.M.7
  • 26
    • 0033593222 scopus 로고    scopus 로고
    • Decreased atherosclerosis in heterozygous LDL receptor-deficient mice expressing the SR-BI transgene
    • 26 Arai T, Wang N, Bezouevski M, Welsh C, Tall AR. Decreased atherosclerosis in heterozygous LDL receptor-deficient mice expressing the SR-BI transgene. J Biol Chem 1999; 274:2366-2371.
    • (1999) J Biol Chem , vol.274 , pp. 2366-2371
    • Arai, T.1    Wang, N.2    Bezouevski, M.3    Welsh, C.4    Tall, A.R.5
  • 27
    • 0031664113 scopus 로고    scopus 로고
    • Production rate determines plasma concentration of large HDL in non-human primates
    • 27 Colvin P, Moriguchi E, Barrett H, Parks J, Rudel L. Production rate determines plasma concentration of large HDL in non-human primates. J Lipid Res 1998; 39:2076-2085.
    • (1998) J Lipid Res , vol.39 , pp. 2076-2085
    • Colvin, P.1    Moriguchi, E.2    Barrett, H.3    Parks, J.4    Rudel, L.5
  • 28
    • 0024592946 scopus 로고
    • High levels of human apolipoprotein A-I in transgenic mice result in increased plasma levels of small HDL particles comparable to human HDL
    • 28 Walsh A, Ito Y, Breslow JL. High levels of human apolipoprotein A-I in transgenic mice result in increased plasma levels of small HDL particles comparable to human HDL. J Biol Chem 1989; 264:6488-6494.
    • (1989) J Biol Chem , vol.264 , pp. 6488-6494
    • Walsh, A.1    Ito, Y.2    Breslow, J.L.3
  • 29
    • 0026057848 scopus 로고
    • Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new HDL size subclasses
    • 29 Rubin EM, Ishida BY, Clift SM, Krauss RM. Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new HDL size subclasses. Proc Natl Acad Sci USA 1991; 88:434-438.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 434-438
    • Rubin, E.M.1    Ishida, B.Y.2    Clift, S.M.3    Krauss, R.M.4
  • 30
    • 0027373567 scopus 로고
    • Protein composition determines the anti-atherogenic properties of HDL in transgenic mice
    • 30 Schultz JR, Verstuyft JG, Gong EL, Nichols AV, Rubin EM. Protein composition determines the anti-atherogenic properties of HDL in transgenic mice. Nature 1993; 365:762-764.
    • (1993) Nature , vol.365 , pp. 762-764
    • Schultz, J.R.1    Verstuyft, J.G.2    Gong, E.L.3    Nichols, A.V.4    Rubin, E.M.5
  • 34
    • 0033597109 scopus 로고    scopus 로고
    • Overexpression of human apolipoprotein A-II in mice induces hypertriglyceridemia due to defective VLDL hydrolysis
    • 34 Boisfer E, Lambert G, Atger V, Tran ON, Pastier D, Benetollo C, et al. Overexpression of human apolipoprotein A-II in mice induces hypertriglyceridemia due to defective VLDL hydrolysis. J Biol Chem 1999; 274:11564-11572. This is the first demonstration that high expression of human apo AII in vivo inhibits LPL and hepatic lipase activities and induces hypertriglyceridaemia.
    • (1999) J Biol Chem , vol.274 , pp. 11564-11572
    • Boisfer, E.1    Lambert, G.2    Atger, V.3    Tran, O.N.4    Pastier, D.5    Benetollo, C.6
  • 35
    • 0027185023 scopus 로고
    • Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice
    • 35 Hedrick CC, Castellani LW, Warden CH, Puppione DL, Lusis AJ. Influence of mouse apolipoprotein A-II on plasma lipoproteins in transgenic mice. J Biol Chem 1993; 268:20676-20682.
    • (1993) J Biol Chem , vol.268 , pp. 20676-20682
    • Hedrick, C.C.1    Castellani, L.W.2    Warden, C.H.3    Puppione, D.L.4    Lusis, A.J.5
  • 37
    • 0031936294 scopus 로고    scopus 로고
    • Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: Evidence of a potentially relevant species-specific interaction with diet
    • 37 Escolà-Gil JC, Marzal-Casacuberta A, Julve-Gil J, Ishida BY, Ordonez-Llanos J, Chan L, et al. Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: evidence of a potentially relevant species-specific interaction with diet. J Lipid Res 1998; 39:457-462.
    • (1998) J Lipid Res , vol.39 , pp. 457-462
    • Escolà-Gil, J.C.1    Marzal-Casacuberta, A.2    Julve-Gil, J.3    Ishida, B.Y.4    Ordonez-Llanos, J.5    Chan, L.6
  • 38
    • 0033058360 scopus 로고    scopus 로고
    • Apo A-II maintains HDL levels in part by inhibition of hepatic lipase: Studies in apo A-II and hepatic lipase knockout mice
    • 38 Weng W, Brandenburg NA, Zhong S, Halkias J, Wu L, Jiang X-C, et al. Apo A-II maintains HDL levels in part by inhibition of hepatic lipase: studies in apo A-II and hepatic lipase knockout mice. J Lipid Res 1999; 40:1064-1070. By inhibiting hepatic lipase activity, human apo AII may maintain HDL cholesterol levels.
    • (1999) J Lipid Res , vol.40 , pp. 1064-1070
    • Weng, W.1    Brandenburg, N.A.2    Zhong, S.3    Halkias, J.4    Wu, L.5    Jiang, X.-C.6
  • 39
    • 0032901331 scopus 로고    scopus 로고
    • A novel endothelial-derived lipase that modulates HDL metabolism
    • 39 Jaye M, Lynch KJ, Krawiek J, Marchadier D, Maugeais C, Doan K, et al. A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 1999; 21:424-428. The overexpression of this novel lipase drastically reduces plasma HDL levels. The endothelial synthesis of this lipase suggests a potential role in reverse cholesterol transport.
    • (1999) Nat Genet , vol.21 , pp. 424-428
    • Jaye, M.1    Lynch, K.J.2    Krawiek, J.3    Marchadier, D.4    Maugeais, C.5    Doan, K.6
  • 40
    • 0018945396 scopus 로고
    • In vitro modulation of the apolipoprotein composition of HDL. Displacement of apolipoprotein A-I from HDL by apolipoprotein A-II
    • 40 Lagocki PA, Scanu AM. In vitro modulation of the apolipoprotein composition of HDL. Displacement of apolipoprotein A-I from HDL by apolipoprotein A-II. J Biol Chem 1980; 255:3701-3706.
    • (1980) J Biol Chem , vol.255 , pp. 3701-3706
    • Lagocki, P.A.1    Scanu, A.M.2
  • 41
    • 7144257856 scopus 로고    scopus 로고
    • The C-terminal helix of human apolipoprotein A-II promotes the fusion of unilamellar liposomes and displaces apolipoprotein A-I from HDL
    • 41 Lambert G, Decout A, Vanloo B, Rouy D, Duverger N, Kalopissis AD, et al. The C-terminal helix of human apolipoprotein A-II promotes the fusion of unilamellar liposomes and displaces apolipoprotein A-I from HDL. Eur J Biochem 1998; 253:328-338.
    • (1998) Eur J Biochem , vol.253 , pp. 328-338
    • Lambert, G.1    Decout, A.2    Vanloo, B.3    Rouy, D.4    Duverger, N.5    Kalopissis, A.D.6
  • 42
    • 0033560938 scopus 로고    scopus 로고
    • Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men
    • 42 Lamarche B, Uffelman KD, Carpentier A, Cohn JS, Steiner G, Barrett PH, Lewis GF. Triglyceride enrichment of HDL enhances in vivo metabolic clearance of HDL apo A-I in healthy men. J Clin Invest 1999; 103:1191-1199. This is the first direct demonstration in humans that triglyceride enrichment of HDL enhances HDL-apo AI clearance.
    • (1999) J Clin Invest , vol.103 , pp. 1191-1199
    • Lamarche, B.1    Uffelman, K.D.2    Carpentier, A.3    Cohn, J.S.4    Steiner, G.5    Barrett, P.H.6    Lewis, G.F.7
  • 43
    • 0027215121 scopus 로고
    • Increased plasma and renal clearance of an exchangeable pool of apolipoprotein A-I in subjects with low levels of HDL cholesterol
    • 43 Horowitz BS, Goldberg IJ, Merab J, Vanni TM, Ramakrishnan R, Ginsberg HN. Increased plasma and renal clearance of an exchangeable pool of apolipoprotein A-I in subjects with low levels of HDL cholesterol. J Clin Invest 1993; 91:1743-1752.
    • (1993) J Clin Invest , vol.91 , pp. 1743-1752
    • Horowitz, B.S.1    Goldberg, I.J.2    Merab, J.3    Vanni, T.M.4    Ramakrishnan, R.5    Ginsberg, H.N.6
  • 44
    • 0021991141 scopus 로고
    • Uptake of HDL-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro
    • 44 Glass C, Pittman RC, Civen M, Steinberg D. Uptake of HDL-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro. J Biol Chem 1985; 260:744-750.
    • (1985) J Biol Chem , vol.260 , pp. 744-750
    • Glass, C.1    Pittman, R.C.2    Civen, M.3    Steinberg, D.4
  • 45
    • 0033056072 scopus 로고    scopus 로고
    • 12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of HDL
    • 12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of HDL. Nat Med 1999; 5:656-661. This is an elegant study identifying cubilin as a high affinity apo AI receptor.
    • (1999) Nat Med , vol.5 , pp. 656-661
    • Kozyraki, R.1    Fyfe, J.2    Kristiansen, M.3    Gerdes, C.4    Jacobsen, C.5    Cui, S.6
  • 47
    • 0031852451 scopus 로고    scopus 로고
    • Kinetic characteristics and regulation of of HDL cholesteryl ester and apolipoprotein transport in the apo A-I-I- mouse
    • 47 Spady DK, Woollett LA, Meidell RS, Hobbs HH. Kinetic characteristics and regulation of of HDL cholesteryl ester and apolipoprotein transport in the apo A-I-I- mouse. J Lipid Res 1998; 39:1483-1492.
    • (1998) J Lipid Res , vol.39 , pp. 1483-1492
    • Spady, D.K.1    Woollett, L.A.2    Meidell, R.S.3    Hobbs, H.H.4
  • 48
    • 0033548092 scopus 로고    scopus 로고
    • Increased HDL, defective hepatic catabolism of apo A-I and apo A-II, and decreased apo A-I mRNA in ob/ob mice
    • 48 Silver DL, Jiang X-C, Tall AR. Increased HDL, defective hepatic catabolism of apo A-I and apo A-II, and decreased apo A-I mRNA in ob/ob mice. J Biol Chem 1999; 274:4140-4146. This interesting study holds promise for the future identification of the putative HDL holoparticle receptor in liver.
    • (1999) J Biol Chem , vol.274 , pp. 4140-4146
    • Silver, D.L.1    Jiang, X.-C.2    Tall, A.R.3
  • 49
    • 0025966616 scopus 로고
    • Isolation and characterization of an apoA-II-containing lipoprotein [LP-A-II:B complex] from plasma VLDL of patients with Tangier disease and type V hyperlipoproteinemia
    • 49 Alaupovic P, Knight-Gibson C, Wang C-S, Downs D, Koren E, Brewer Jr HB, Gregg RE. Isolation and characterization of an apoA-II-containing lipoprotein [LP-A-II:B complex] from plasma VLDL of patients with Tangier disease and type V hyperlipoproteinemia. J Lipid Res 1991; 32:9-19.
    • (1991) J Lipid Res , vol.32 , pp. 9-19
    • Alaupovic, P.1    Knight-Gibson, C.2    Wang, C.-S.3    Downs, D.4    Koren, E.5    Brewer H.B., Jr.6    Gregg, R.E.7
  • 50
    • 0027330901 scopus 로고
    • Lack of apo A-I is not associated with increased susceptibility to atherosclerosis in mice
    • 50 Li H, Reddick RL, Maeda N. Lack of apo A-I is not associated with increased susceptibility to atherosclerosis in mice. Arterioscler Thromb 1993; 13:1814-1821.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1814-1821
    • Li, H.1    Reddick, R.L.2    Maeda, N.3
  • 51
    • 0029992667 scopus 로고    scopus 로고
    • Dramatically decreased HDL cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility
    • 51 Weng W, Breslow JL. Dramatically decreased HDL cholesterol, increased remnant clearance, and insulin hypersensitivity in apolipoprotein A-II knockout mice suggest a complex role for apolipoprotein A-II in atherosclerosis susceptibility. Proc Natl Acad Sci USA 1996; 93:14788-14794.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14788-14794
    • Weng, W.1    Breslow, J.L.2
  • 53
    • 0028883354 scopus 로고
    • Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice
    • 53 Bellosta S, Mahley RW, Sanan DA, Murata J, Newland DL, Taylor JM, Pitas RE. Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice. J Clin Invest 1995; 96:2170-2179.
    • (1995) J Clin Invest , vol.96 , pp. 2170-2179
    • Bellosta, S.1    Mahley, R.W.2    Sanan, D.A.3    Murata, J.4    Newland, D.L.5    Taylor, J.M.6    Pitas, R.E.7
  • 54
    • 0032527911 scopus 로고    scopus 로고
    • Substitution of the carboxyl-terminal domain of apo A-I with apo A-II sequences restores the potential of HDL to reduce the progression of atherosclerosis in apo E knockout mice
    • 54 Holvoet P, Danloy S, Deridder E, Lox M, Bernar H, Dhoest A, Collen D. Substitution of the carboxyl-terminal domain of apo A-I with apo A-II sequences restores the potential of HDL to reduce the progression of atherosclerosis in apo E knockout mice. J Clin Invest 1998; 102:379-385.
    • (1998) J Clin Invest , vol.102 , pp. 379-385
    • Holvoet, P.1    Danloy, S.2    Deridder, E.3    Lox, M.4    Bernar, H.5    Dhoest, A.6    Collen, D.7


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