Multiple arterial thromboembolisms in a patient with the 20210 A prothrombin gene mutation

Archives of Surgery

Volumn 135, Issue 6, 2000, Pages 721-722

  Seeburger, Jeffrey L ^a   Stepak, Michael ^a   Fukuchi, Steven G ^b   Siegel, Jamie E ^c   Rolandelli, Rolando H ^b,d  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b TEMPLE UNIVERSITY HOSPITAL   (United States)

^c UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^d TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTHROMBIN A;

ADULT; ARTERY THROMBOSIS; ARTICLE; CASE REPORT; ENVIRONMENTAL FACTOR; FEMALE; GENE MUTATION; GENETIC DISORDER; HUMAN; HYPERCOAGULABILITY; PRIORITY JOURNAL; THROMBOEMBOLISM; THROMBOPHILIA;

EID: 0034079456     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: 10.1001/archsurg.135.6.721     Document Type: Article

References (4)

1. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood. 1996;88:3698-3703.
2. Kapur RK, Mills LA, Spitzer SG, Hultin MB. A prothrombin gene mutation is significantly associated with venous thrombosis. Arterioscler Thromb Vasc Biol. 1997; 17:2875-2879.
3. Rosendaal FR, Siscovick DS, Schwartz SM, Psaty BM, Raghunathan TE, Vos HL. A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women. Blood. 1997;90:1747-1750.
4. De Stefano V, Chiusolo P, Paciaroni K, et al. Prothrombin G20210A mutant genotype is a risk factor for cerebrovascular ischemic disease in young patients. Blood. 1998;91:3562-3565.