Design of stable biologically active recombinant lutropin analogs

Nature Biotechnology

Volumn 15, Issue 7, 1997, Pages 663-667

  Garcia Campayo, Vicenta ^a   Sato, Asomi ^a   Hirsch, Burkhard ^b   Sugahara, Tadashi ^a   Muyan, Mesut ^a   Hsueh, Aaron J W ^b   Boime, Irving ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Lutropin; Single chain gonadotropin; Structure function

Indexed keywords

CHORIONIC GONADOTROPIN; CYCLIC AMP; LUTEINIZING HORMONE DERIVATIVE; MONOCLONAL ANTIBODY; RECOMBINANT LUTEINIZING HORMONE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BETA CHAIN; CHO CELL; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG RECEPTOR BINDING; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BASE SEQUENCE; BIOTECHNOLOGY; CHO CELLS; CRICETINAE; DNA PRIMERS; DRUG DESIGN; DRUG STABILITY; HUMANS; LUTEINIZING HORMONE; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RECEPTORS, LH; TRANSFECTION;

ANIMALIA;

EID: 0030816072     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt0797-663     Document Type: Article

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