No clinically important effects on intraocular pressure after short-term administration of sildenafil citrate (Viagra)

American Journal of Ophthalmology

Volumn 129, Issue 5, 2000, Pages 675-676

  Yajima, Tadataka ^a   Yajima, Youichi ^a   Koppiker, Nandan ^b   Grunwald, Juan E ^c   Laties, Alan M ^c  

^a Kaiyo Clinic   (Japan)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; SILDENAFIL;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG SAFETY; ERECTILE DYSFUNCTION; GLAUCOMA; HUMAN; HUMAN EXPERIMENT; INTRAOCULAR PRESSURE; MAJOR CLINICAL STUDY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PUPIL; PUPILLOMETRY; SHORT SURVEY; VOLUNTEER;

EID: 0034078088     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9394(00)00375-5     Document Type: Article

References (6)

1. Ballard S.A., Gingell C.J., Tang K., Turner L.A., Price M.E., Naylor A.M. Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes. J Urol. 59:1998;2164-2171.
2. Beavo J.A. Cyclic nucleotide phosphodiesterases functional implications of multiple isoforms . Physiol Rev. 75:1995;725-748.
3. Morales A., Gingell C., Collins M., Wicker P.A., Osterloh I.H. Clinical safety of oral sildenafil citrate (VIAGRA™) in the treatment of erectile dysfunction. Int J Impot Res. 10:1998;69-74.
4. Johnson D.H., Brubaker R.F. Glaucoma an overview . Mayo Clin Proc. 61:1986;59-67.
5. Grunwald J.E., Iannaccone A., DuPont J. Effect of isosorbide mononitrate on the human optic nerve and choroidal circulations. Br J Ophthalmol. 83:1999;162-167.
6. Buerk D.G., Riva D.E., Cranstoun S.D. Nitric oxide has a vasodilatory role in cat optic nerve head during flicker stimuli. Microvasc Res. 52:1999;13-26.