Genetic predispositions for immunological features in chronic liver diseases other than autoimmune hepatitis

Journal of Hepatology

Volumn 24, Issue 1, 1996, Pages 52-59

  Czaja, Albert J ^a   Carpenter, Herschel A ^a   Santrach, Paula J ^a   Moore, S Breanndan ^a  

^a MAYO CLINIC   (United States)

Author keywords

Autoimmunity; Genetic predisposition; HLA associations

Indexed keywords

LEUKOCYTE ANTIGEN;

ADULT; ARTICLE; AUTOIMMUNE HEPATITIS; AUTOIMMUNITY; CONTROLLED STUDY; FEMALE; GENETIC PREDISPOSITION; HLA SYSTEM; HUMAN; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 0030069520     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(96)80186-3     Document Type: Article

References (56)

1. Opelz G, Vogten AJM, Summerskill WHJ, Schalm SW, Terasaki PI. HLA determinants in chronic active liver disease: possible relation of HLA-Dw3 to prognosis. Tissue Antigens 1977; 9: 36-40.
2. Williams RM, Martin S, Falchuk KR, Trey C, Dubey DP, Cannady WG, Fitzpatrick D, Noreen H, Dupont B, Yunis EJ. Increased frequency of HLA-DRW4 in chronic active hepatitis. Vox Sang 1978; 35: 366-9.
3. Mackay IR, Tait BD. HLA associations with autoimmune-type chronic active hepatitis: identification of B8-DRw3 haplotype by family studies. Gastroenterology 1980; 79: 95-8.
4. Donaldson PT, Doherty DG, Hayllar KM, McFarlane IG, Johnson PJ, Williams R. Susceptibility to autoimmune chronic active hepatitis: human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors. Hepatology 1990; 13: 701-6.
5. Doherty DG, Donaldson PT, Underhill JA, Farrant JM, Duthie A, Mieli-Vergani G, McFarlane IG, Johnson PJ, Eddleston ALWF, Mowat AP, Williams R. Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis. Hepatology 1994; 19: 609-15.
6. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Genetic predispositions for the immunological features of chronic active hepatitis. Hepatology 1993; 18: 816-22.
7. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Significance of HLA DR4 in type 1 autoimmune hepatitis. Gastroenterology 1993; 105: 1502-7.
8. Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Immunologic features and HLA associations in chronic viral hepatitis. Gastroenterology 1995; 108: 157-64.
9. Wiesner RH, LaRusso NF, Ludwig J, Dickson ER. Comparison of the clinicopathologic features of primary sclerosing cholangitis and primary biliary cirrhosis. Gastroenterology 1985; 88: 108-14.
10. Mackay IR, Gershwin ME. Primary biliary cirrhosis: current knowledge, perspectives, and future directions. Semin Liver Dis 1989; 9: 149-57.
11. Wiesner RH, LaRusso NF. Clinicopathologic features of the syndrome of primary sclerosing cholangitis. Gastroenterology 1980; 79: 200-6.
12. Wiesner RH. Current concepts in primary sclerosing cholangitis. Mayo Clin Proc 1994; 69: 969-82.
13. Hay JE, Czaja AJ, Rakela J, Ludwig J. The nature of unexplained chronic aminotransferase elevations of a mild to moderate degree in asymptomatic patients. Hepatology 1989; 9: 193-7.
14. Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Tetri BA. Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 1994; 107: 1103-9.
15. Chapman RW, Varghese Z, Gaul R, Patel G, Kokinon N, Sherlock S. Association of primary sclerosing cholangitis with HLA-B8. Gut 1983; 24: 38-41.
16. Prochazka EJ, Terasaki PI, Sik Park M, Goldstein LI, Busuttil RW. Association of primary sclerosing cholangitis with HLA-DRw52a. N Engl J Med 1990; 322: 1842-4.
17. Zetterquist H, Broome U, Einarsson K, Olerup O. HLA class II genes in primary sclerosing cholangitis and chronic inflamatory bowel disease: no HLA-DRw52a association in Swedish patients with sclerosing cholangitis. Gut 1992; 33: 942-6.
18. Mehal WZ, Dennis Lo Y-M, Wordsworth BP, Neuberger JM, Hubscher SC, Fleming KA, Chapman RW HLA DR4 is a marker for rapid disease progression in primary sclerosing cholangitis. Gastroenterology 1994; 106: 160-7.
19. Gores GJ, Moore SB, Fisher LD, Powell FC, Dickson ER. Primary biliary cirrhosis: associations with class II major histocompatibility complex antigens. Hepatology 1987; 7: 889-92.
20. Manns MP, Bremm A, Schneider PM, Notghi A, Gerken G, Prager-Eberle M, Stradmann-Bellinghausen B, Meyer zum Buschenfelde K-H, Rittner C. HLA DRw8 and complement C4 deficiency as risk factors in primary biliary cirrhosis. Gastroenterology 1991; 101: 1367-73.
21. Mehal WZ, Gregory WL, Dennis Lo Y-M, Cross SJ, Fleming KA, Bassendine MF, James OFW, Campbell RD, Chapman RW, Rosenberg WMC. Defining the immunogenetic susceptibility to primary biliary cirrhosis. Hepatology 1994; 20: 1213-19.
22. Mella JG, Roschmann E, Maier K-P, Volk BA. Association of primary biliary cirrhosis with the allele HLA-DPB1*0301 in a German population. Hepatology 1995; 21: 398-402.
23. Mieli-Vergani G, Lobo-Yeo A, McFarlane BM, McFarlane IG, Mowat AP, Vergani D. Different immune mechanisms leading to autoimmunity in primary sclerosing cholangitis and autommune chronic active hepatitis of childhood. Hepatology 1989; 9: 198-203.
24. Perdigoto R, Carpenter HA, Czaja AJ. Frequency and significance of chronic ulcerative colitis in severe corticosteroid-treated autoimmune hepatitis. J Hepatol 1992; 14: 325-31.
25. Johnson PJ, McFarlane IG, Alvarez F, Bianchi FB, Bianchi L, Burroughs A, Chapman RW, Czaja AJ, Desmet V, Edleston ALWF, Gerber MA, Hoofnagle JH, Kakumu S, MacSween RNM, Maddrey WC, Manns MP, Meyer zum Buschenfelde K-H, Mieli-Vergani G, Portmann BC, Reed WD, Schalm SW, Scheuer PJ, Toda G, Tsuji T, Tygstrup N, Vergani D, Zeniya M. Meeting Report. International Autoimmune Hepatitis Group. Hepatology 1993; 18: 998-1005.
26. Czaja AJ. Autoimmune hepatitis: evolving concepts and treatment strategies. Dig Dis Sci 1995; 40: 435-56.
27. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 1994; 19: 1513-20.
28. Ludwig J and the International Working Party. Terminology of chronic hepatitis, hepatic allograft rejection, and nodular lesions of the liver: summary of recommendations developed by an international working party by the World Congresses of Gastroenterology, Los Angeles, 1994. Am J Gastroenterol 1994; 89: S177-S181.
29. International Working Party. Terminology of chronic hepatitis. Am J Gastroenterol 1995; 90: 181-9.
30. Czaja AJ, Davis GL, Ludwig J, Baggenstoss AH, Taswell HF. Autoimmune features as determinants of prognosis in steroid-treated chronic active hepatitis of uncertain etiology. Gastroenterology 1983; 85: 713-7.
31. Kenny RP, Czaja AJ, Ludwig J, Dickson ER. Frequency and significance of antimitochondrial antibodies in severe chronic active hepatitis. Dig Dis Sci 1986; 31: 705-11.
32. Czaja AJ, Nishioka M, Morshed SA, Hachiya T. Patterns of nuclear immunofluorescence and reactivities to recombinant nuclear antigens in autommune hepatitis. Gastroenterology 1994; 107: 200-7.
33. Czaja AJ, Manns MP, Homburger HA. Frequency and significance of antibodies to liver/kidney microsome type 1 in adults with chronic active hepatitis. Gastroenterology 1992; 103: 1290-5.
34. Fulthorpe AJ, Roitt IM, Doniach D, Couchman K. A stable sheep cell preparation for detecting thyroglobulin antibodies and its clinical application. J Clin Pathol 1961; 14: 654-60.
35. Bird T, Stephenson J. Evaluation of a tanned red cell technique for thyroid microsomal antibodies. J Clin Pathol 1973; 26: 623-7.
36. Czaja AJ, Rakela J, Hay JE, Moore SB. Clinical and prognostic implications of human leukocyte antigen B8 in corticosteroid-treated severe autoimmune chronic active hepatitis. Gastroenterology 1990; 98: 1587-93.
37. Bidwell JL, Bidwell EA, Savage DA, Middleton D, Klouda PT, Bradley BA. A DNA-RFLP typing system that positively identifies serologically well-defined and ill-defined HLA-DR and DQ alleles, including DRw10. Trnasplantation 1988; 45: 640-6.
38. Noreen HJ, Davidson ML, McCullough J, Bach FH, Segall M. HLA class II typing by restriction fragment length polymorphism (RFLP) in unrelated bone marrow transplant patients. Transplant Proc 1989; 21: 2968-70.
39. Mytilineos J, Scherer S, Opelz G. Comparison of RFLP-DR beta and serological HLA-DR typing in 1500 individuals. Transplantation 1990; 50: 870-3.
40. Bodmer JG, Marsh SGE, Albert ED, Bodmer WF, Dupont B, Erlich HA, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GMT, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1991. Human Immunol 1992; 34: 4-18.
41. Manns MP, Griffin KJ, Sullivan KF, Johnson EF. LKM-1 autoantibodies recognize a short linear sequence in P450IID6, a cytochrome P-450 monooxygenase. J Clin Invest 1991; 88: 1370-8.
42. O'Brien CJ, Vento S, Donaldson PT, McSorley CG, McFarlane IG, Williams R, Eddleston ALWF. Cell-mediated immunity and suppressor-T-cell defects to liver-derived antigens in families of patients with autoimmune chronic active hepatitis. Lancet 1986; i: 350-3.
43. Mayet W-J, Hess G, Gerken G, Rossol S, Voth R, Manns M, Meyer zum Buschenfelde K-H. Treatment of chronic type B hepatitis with recombinant alpha-interferon induces auto-antibodies not specific for autoimmune chronic hepatitis. Hepatology 1989; 10: 24-8.
44. Fattovich G, Betterle C, Brollo L, Pedini B, Giustina G, Realdi G, Alberti A, Ruol A. Autoantibodies during alpha-interferon therapy for chronic hepatitis B. J Med Virol 1991; 34: 132-5.
45. Vento S, DiPerri G, Garofano T, Cosco L, Concia E, Ferraro T, Bassetti D. Hazards of interferon therapy for HBV-sero-negative chronic hepatitis. Lancet 1989; ii: 926.
46. Papo T, Marcellin P, Bernuau J, Durand F, Poynard T, Benhamou J-P. Autoimmune chronic hepatitis exacerbated by alpha-interferon. Ann Intern Med 1992; 116: 51-3.
47. Shindo M, DiBisceglie AM, Hoofnagle JH. Acute exacerbation of liver disease during interferon alfa therapy for chronic hepatitis C. Gastroenterology 1992; 102: 1406-8.
48. Griffing WL, Moore SB, Luthra HS, McKenna CH, Fathman CG. Associations of antibodies to native DNA with HLA-DRw3: a possible major histocompatibility complex-linked human immune response gene. J Exp Med 1980; 152: 319s-25s.
49. Rees AJD, Peters DK, Compston DAS, Batchelor JR. Strong association between HLA-DRw2 and antibody-mediated Goodpasture's syndrome. Lancet 1978; i: 966-8.
50. Naeim F, Keesey JC, Herrmann C Jr, Lindström J, Zeller E, Walford RL. Association of HLA-B8, DRw3, and anti-acetylcholine receptor antibodies in myasthenia gravis. Tissue Antigens 1978; 12: 381-6.
51. Lunel F. Hepatitis C virus and autoimmunity: fortuitous association or reality? Gastroenterology 1994; 107: 1550-5.
52. Manabe K, Donaldson PT, Underhill JA, Doherty DG, Mieli-Vergani G, McFarlane IG, Eddleston ALWF, Williams R. Human leukocyte antigen A1-B8-DR3-DQ2-DPB1*0401 extended haplotype in autoimmune hepatitis. Hepatology 1993; 18: 1334-7.
53. Scully LJ, Toze C, Sengar DPS, Goldstein R. Early-onset autoimmune hepatitis is associated with a C4A gene deletion. Gastroenterology 1993; 104: 1478-84.
54. Doherty DG, Underhill JA, Donaldson PT, Manabe K, Mieli-Vergani G, Eddleston ALWF, Vergani D, Demaine AG, Williams R. Polymorphism in the human complement C4 genes and genetic susceptibility to autoimmune hepatitis. Autoimmunity 1994; 18: 243-9.
55. Thomas HC, Montano L, Goodall A, de Koning R, Oladapo J, Wiedman KH. Immunological mechanisms in chronic hepatitis B virus infection. Hepatology 1982; 2: 116S-21S.
56. Gonzalez-Peralta RP, Davis GL, Lau JYN. Pathogenetic mechanisms of hepatocellular damage in chronic hepatitis C virus infection. J Hepatol 1994; 21: 255-9.