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Volumn 30, Issue 6, 2000, Pages 1778-1784

Double mutant MRL-Ipr/Ipr-gld/gld cells fail to trigger Ipr-graft-versus-host disease in syngeneic wild-type recipient mice, but can induce wild-type B cells to make autoantibody

Author keywords

Anti nuclear antibody; Fas ligand; Graft versus host disease; Inflammation; Radiation chimera

Indexed keywords

AUTOANTIBODY; FAS ANTIGEN; FAS LIGAND;

EID: 0034076902     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200006)30:6<1778::AID-IMMU1778>3.0.CO;2-D     Document Type: Article
Times cited : (8)

References (35)
  • 1
    • 0025875259 scopus 로고
    • Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen, P. L. and Eisenberg, R. A., Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 1991. 9: 243-269.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 2
    • 0026568919 scopus 로고
    • Lymphproliferative disorder in mice explained by defects in Fas antigen that mediate apoptosis
    • Watanabe-Fukunaga, R., Brannan, C., Copeland, N., Jenkins, N. and Nagata, S., Lymphproliferative disorder in mice explained by defects in Fas antigen that mediate apoptosis. Nature 1992. 356: 314.
    • (1992) Nature , vol.356 , pp. 314
    • Watanabe-Fukunaga, R.1    Brannan, C.2    Copeland, N.3    Jenkins, N.4    Nagata, S.5
  • 3
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand
    • Takahashi, T., Tanaka M., Brannan, C., Jenkins, N., Copeland, N., Suda, T. and Nagata, S., Generalized lymphoproliferative disease in mice caused by a point mutation in the Fas ligand. Cell 1994. 76: 969.
    • (1994) Cell , vol.76 , pp. 969
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.3    Jenkins, N.4    Copeland, N.5    Suda, T.6    Nagata, S.7
  • 4
    • 0021149927 scopus 로고
    • One-way occurrence of graft-versus-host disease in bone marrow chimeras between congenic MRL mice
    • Fujiwara, M. and Kariyone, A., One-way occurrence of graft-versus-host disease in bone marrow chimeras between congenic MRL mice. Immunology 1984. 53: 251-256.
    • (1984) Immunology , vol.53 , pp. 251-256
    • Fujiwara, M.1    Kariyone, A.2
  • 6
    • 0028285926 scopus 로고
    • Comparison of wasting syndrome in [MRL lpr/lpr → MRL +/+] chimera and graft versus host disease in [B10.D2 → BALB/c] chimera and an attempt to transfer the wasting syndrome in [MRL lpr/lpr → MRL+/+] to MRL +/+ mice
    • Aihara, M., Aihara, Y. and Nakajima, H., Comparison of wasting syndrome in [MRL lpr/lpr → MRL +/+] chimera and graft versus host disease in [B10.D2 → BALB/c] chimera and an attempt to transfer the wasting syndrome in [MRL lpr/lpr → MRL+/+] to MRL +/+ mice. J. Dermatol. Sci. 1994. 7: 107-118.
    • (1994) J. Dermatol. Sci. , vol.7 , pp. 107-118
    • Aihara, M.1    Aihara, Y.2    Nakajima, H.3
  • 7
    • 0028245514 scopus 로고
    • Analyses of lpr-GVHD by adoptive transfer experiments using MRL/lpr-Thy-1.1 congenic mice
    • Hosaka, N., Nagata, N., Nakagawa T., Miyashima, S., Yasumizu, R. and Ikehara, S., Analyses of lpr-GVHD by adoptive transfer experiments using MRL/lpr-Thy-1.1 congenic mice. Autoimmunity 1994. 17: 217-224.
    • (1994) Autoimmunity , vol.17 , pp. 217-224
    • Hosaka, N.1    Nagata, N.2    Nakagawa, T.3    Miyashima, S.4    Yasumizu, R.5    Ikehara, S.6
  • 8
    • 0025109809 scopus 로고
    • Bone marrow transplantation from mutant lpr/lpr mice. Functional abnormalities rather than alloantigenic differences appear to determine the development of a graft-vs.-host-like syndrome
    • Allen, R. D., Marshall, J. D., Roths, J. B. and Sidman, C. L., Bone marrow transplantation from mutant lpr/lpr mice. Functional abnormalities rather than alloantigenic differences appear to determine the development of a graft-vs.-host-like syndrome. Eur. J. Immunol. 1990. 20: 2057-2066.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 2057-2066
    • Allen, R.D.1    Marshall, J.D.2    Roths, J.B.3    Sidman, C.L.4
  • 9
    • 0030027414 scopus 로고    scopus 로고
    • Prevention of lpr-graft-versus-host disease and transfer of autoimmune disease in normal C57BL76 mice by transplantation of bone marrow cells plus bones (stromal cells) from MRL/lpr mice
    • Miyashima, S., Nagata, N., Nakagawa, T., Hosaka, N., Takeuchi, K., Ogawa, R. and Ikehara, S., Prevention of lpr-graft-versus-host disease and transfer of autoimmune disease in normal C57BL76 mice by transplantation of bone marrow cells plus bones (stromal cells) from MRL/lpr mice. J. Immunol. 1996. 156: 79-84.
    • (1996) J. Immunol. , vol.156 , pp. 79-84
    • Miyashima, S.1    Nagata, N.2    Nakagawa, T.3    Hosaka, N.4    Takeuchi, K.5    Ogawa, R.6    Ikehara, S.7
  • 10
    • 0030589301 scopus 로고    scopus 로고
    • A major role for the Fas pathway in acute graft-versus-host disease
    • Via, C. S., Nguyen, P., Shustov, A., Drappa, J. and Elkon, K. B., A major role for the Fas pathway in acute graft-versus-host disease. J. Immunol. 1996. 157: 5387-5393.
    • (1996) J. Immunol. , vol.157 , pp. 5387-5393
    • Via, C.S.1    Nguyen, P.2    Shustov, A.3    Drappa, J.4    Elkon, K.B.5
  • 11
    • 0031020849 scopus 로고    scopus 로고
    • Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function
    • Baker, M. B., Riley, R. L., Podack, E. R. and Levy, R. B., Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function. Proc. Natl. Acad. Sci. USA 1997. 94: 1366-1371.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1366-1371
    • Baker, M.B.1    Riley, R.L.2    Podack, E.R.3    Levy, R.B.4
  • 12
    • 0030823702 scopus 로고    scopus 로고
    • Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation
    • Graubert, T. A., DiPersio, J. F., Russell, J. H. and Ley, T. J., Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation. J. Clin. Invest. 1997. 100: 904-911.
    • (1997) J. Clin. Invest. , vol.100 , pp. 904-911
    • Graubert, T.A.1    DiPersio, J.F.2    Russell, J.H.3    Ley, T.J.4
  • 13
    • 0030050453 scopus 로고    scopus 로고
    • Cytotoxic T cells deficient in both functional Fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce acute graft-versus-host disease
    • Braun, M. Y., Lowin, B., French, L., Acha-Orbea, H. and Tschopp, J., Cytotoxic T cells deficient in both functional Fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce acute graft-versus-host disease. J. Exp. Med. 1996. 183: 657-661.
    • (1996) J. Exp. Med. , vol.183 , pp. 657-661
    • Braun, M.Y.1    Lowin, B.2    French, L.3    Acha-Orbea, H.4    Tschopp, J.5
  • 15
    • 0025873217 scopus 로고
    • Hematopoietic cell transfers between C57BL/6 mice differing at the lpr or gld locus
    • Montecino-Rodriguez, E. M. and Loor, F., Hematopoietic cell transfers between C57BL/6 mice differing at the lpr or gld locus. Immunology 1991. 74: 127-131.
    • (1991) Immunology , vol.74 , pp. 127-131
    • Montecino-Rodriguez, E.M.1    Loor, F.2
  • 16
    • 0025085992 scopus 로고
    • Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules
    • Allen, R. D., Marshall, J. D., Roths, J. B. and Sidman, C. L., Differences defined by bone marrow transplantation suggest that lpr and gld are mutations of genes encoding an interacting pair of molecules. J. Exp. Med. 1990. 172: 1367-1375.
    • (1990) J. Exp. Med. , vol.172 , pp. 1367-1375
    • Allen, R.D.1    Marshall, J.D.2    Roths, J.B.3    Sidman, C.L.4
  • 17
    • 0023280008 scopus 로고
    • Selective elimination of non-lpr lymphoid cells in mice undergoing lpr-mediated graft-vs-host disease
    • Perkins, D. L., Michaelson, J., Glaser, R. M. and Marshak-Rothstein, A., Selective elimination of non-lpr lymphoid cells in mice undergoing lpr-mediated graft-vs-host disease. J. Immunol. 1987. 139: 1406.
    • (1987) J. Immunol. , vol.139 , pp. 1406
    • Perkins, D.L.1    Michaelson, J.2    Glaser, R.M.3    Marshak-Rothstein, A.4
  • 18
    • 0032127448 scopus 로고    scopus 로고
    • Involvement of Fas-mediated apoptosis in the hematopoietic progenitor cells of graft-versus-host reaction-associated myelosuppression
    • Mori, T., Nishimura, T., Ikeda, Y., Hotta, T., Yagita, H. and Ando, K., Involvement of Fas-mediated apoptosis in the hematopoietic progenitor cells of graft-versus-host reaction-associated myelosuppression. Blood 1998. 92: 101-107.
    • (1998) Blood , vol.92 , pp. 101-107
    • Mori, T.1    Nishimura, T.2    Ikeda, Y.3    Hotta, T.4    Yagita, H.5    Ando, K.6
  • 19
    • 0032100478 scopus 로고    scopus 로고
    • Differential effects of anti-Fas ligand and anti-tumor necrosis factor α antibodies on acute graft-versus-host disease pathologies
    • Hattori, K., Hirano, T., Miyajima, H., Yamakawa, N., Tateno, M., Oshimi K., Kayagaki N., Yagita, H. and Okumura, K., Differential effects of anti-Fas ligand and anti-tumor necrosis factor α antibodies on acute graft-versus-host disease pathologies. Blood 1998. 91: 4051-4055.
    • (1998) Blood , vol.91 , pp. 4051-4055
    • Hattori, K.1    Hirano, T.2    Miyajima, H.3    Yamakawa, N.4    Tateno, M.5    Oshimi, K.6    Kayagaki, N.7    Yagita, H.8    Okumura, K.9
  • 20
    • 0028835952 scopus 로고
    • Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders
    • Watanabe, D., Suda, T., Hashimoto, H. and Nagata, S., Constitutive activation of the Fas ligand gene in mouse lymphoproliferative disorders. EMBO J. 1995. 14: 12-18.
    • (1995) EMBO J. , vol.14 , pp. 12-18
    • Watanabe, D.1    Suda, T.2    Hashimoto, H.3    Nagata, S.4
  • 21
    • 0028928654 scopus 로고
    • Massive upregulation of the Fas ligand in lpr and gld mice: Implications for Fas regulation and the graft-versus-host disease like wasting syndrome
    • Chu, J. L., Ramos, P., Rosendorff, A., Nikolic-Zugic, J., Lacy, E., Matsuzawa A. and Elkon, K. B., Massive upregulation of the Fas ligand in lpr and gld mice: implications for Fas regulation and the graft-versus-host disease like wasting syndrome. J. Exp. Med. 1995. 181: 393-398.
    • (1995) J. Exp. Med. , vol.181 , pp. 393-398
    • Chu, J.L.1    Ramos, P.2    Rosendorff, A.3    Nikolic-Zugic, J.4    Lacy, E.5    Matsuzawa, A.6    Elkon, K.B.7
  • 22
    • 0027314703 scopus 로고
    • Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide
    • Russell, J. H., Rush, B., Weaver, C. and Wang, R., Mature T cells of autoimmune lpr/lpr mice have a defect in antigen-stimulated suicide. Proc. Natl. Acad. Sci. USA 1993. 90: 4409.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 4409
    • Russell, J.H.1    Rush, B.2    Weaver, C.3    Wang, R.4
  • 23
    • 0027284016 scopus 로고
    • Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells
    • Russell, J. H. and Wang, R., Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated, mature T cells. Eur. J. Immunol. 1993. 23: 2379-2384.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 2379-2384
    • Russell, J.H.1    Wang, R.2
  • 24
    • 0030296281 scopus 로고    scopus 로고
    • Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of of CPP32-mediated apoptosis
    • Sekine, C., Yagita, H., Kobata, T., Hasunuma, T., Nishioka, K. and Okumura, K., Fas-mediated stimulation induces IL-8 secretion by rheumatoid arthritis synoviocytes independently of of CPP32-mediated apoptosis. Biochem. Biophys. Res. Commun. 1996. 228: 14.
    • (1996) Biochem. Biophys. Res. Commun. , vol.228 , pp. 14
    • Sekine, C.1    Yagita, H.2    Kobata, T.3    Hasunuma, T.4    Nishioka, K.5    Okumura, K.6
  • 25
    • 0031730436 scopus 로고    scopus 로고
    • Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand
    • Miwa, K., Asano, M., Horai, R., Iwakura, Y., Nagata, S. and Suda, T., Caspase 1-independent IL-1β release and inflammation induced by the apoptosis inducer Fas ligand. Nat. Med. 1998. 4: 1287-1292.
    • (1998) Nat. Med. , vol.4 , pp. 1287-1292
    • Miwa, K.1    Asano, M.2    Horai, R.3    Iwakura, Y.4    Nagata, S.5    Suda, T.6
  • 26
    • 0031973637 scopus 로고    scopus 로고
    • Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand
    • Suzuki, I. and Fink. P. J., Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand. J. Exp. Med. 1998. 187: 123-128.
    • (1998) J. Exp. Med. , vol.187 , pp. 123-128
    • Suzuki, I.1    Fink, P.J.2
  • 28
    • 0026094303 scopus 로고
    • B lymphocytes from the autoimmune-prone mouse strain MRL/ lpr manifest an intrinsic defect in MRL/lpr ↔ DBA/2 chimeras
    • Nemazee, D., Guiet, C., Buerki, K. and Marshak-Rothstein, A., B lymphocytes from the autoimmune-prone mouse strain MRL/ lpr manifest an intrinsic defect in MRL/lpr ↔ DBA/2 chimeras. J. Immunol. 1991. 147: 2536-2539.
    • (1991) J. Immunol. , vol.147 , pp. 2536-2539
    • Nemazee, D.1    Guiet, C.2    Buerki, K.3    Marshak-Rothstein, A.4
  • 29
    • 0026532676 scopus 로고
    • Tetraparental mice reveal complex cellular interactions of the mutant, autoimunity-inducing lpr gene
    • Katagiri, T., Azuma, S., Toyoda, Y., Mori, S., Kono, K., Cohen, P. L. and Eisenberg, R. A., Tetraparental mice reveal complex cellular interactions of the mutant, autoimunity-inducing lpr gene. J. Immunol. 1992. 148: 430-438.
    • (1992) J. Immunol. , vol.148 , pp. 430-438
    • Katagiri, T.1    Azuma, S.2    Toyoda, Y.3    Mori, S.4    Kono, K.5    Cohen, P.L.6    Eisenberg, R.A.7
  • 30
    • 0027500801 scopus 로고
    • Correction of gld autoimmunity by co-infusion of normal bone marrow suggests that gld is a mutation of the Fas ligand gene
    • Sobel, E. S., Kakkanaiah, V. N., Cohen, P. L. and Eisenberg, R. A., Correction of gld autoimmunity by co-infusion of normal bone marrow suggests that gld is a mutation of the Fas ligand gene. Int. Immunol. 1993. 5: 1275-1278.
    • (1993) Int. Immunol. , vol.5 , pp. 1275-1278
    • Sobel, E.S.1    Kakkanaiah, V.N.2    Cohen, P.L.3    Eisenberg, R.A.4
  • 31
    • 0028080948 scopus 로고
    • Defective T cells from gld mice play a pivitol role in development of Thy1.2+B220+ cells and autoimmunity
    • Yasutomo, K., Maeda K., Nagata, S., Nagasawa, H., Okada, K., Good, R. A., Kuroda, Y. and Himeno, K., Defective T cells from gld mice play a pivitol role in development of Thy1.2+B220+ cells and autoimmunity. J. Immunol. 1994. 153: 5855-5864.
    • (1994) J. Immunol. , vol.153 , pp. 5855-5864
    • Yasutomo, K.1    Maeda, K.2    Nagata, S.3    Nagasawa, H.4    Okada, K.5    Good, R.A.6    Kuroda, Y.7    Himeno, K.8
  • 32
    • 0028833565 scopus 로고
    • In vivo depletion of Thy-1-positive cells originating from normal bone marrow abrogates the suppression of gld disease in normal-gld mixed bone marrow chimeras
    • MacDonald, G. C., Kakkanaiah, V. N., Sobel, E. S., Cohen, P. L. and Eisenberg, R. A., In vivo depletion of Thy-1-positive cells originating from normal bone marrow abrogates the suppression of gld disease in normal-gld mixed bone marrow chimeras. J. Immunol. 1995. 154: 444-449.
    • (1995) J. Immunol. , vol.154 , pp. 444-449
    • MacDonald, G.C.1    Kakkanaiah, V.N.2    Sobel, E.S.3    Cohen, P.L.4    Eisenberg, R.A.5
  • 33
    • 0031213797 scopus 로고    scopus 로고
    • + T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL
    • + T cells reactivated with superantigen are both more sensitive to FasL-mediated killing and express a higher level of FasL. Cell. Immunol. 1997. 179: 153-164.
    • (1997) Cell. Immunol. , vol.179 , pp. 153-164
    • Wang, J.K.M.1    Zhu, B.2    Ju, S.-T.3    Tschopp, J.4    Marshak-Rothstein, A.5
  • 34
    • 0023107230 scopus 로고
    • The lpr gene is associated with resistance to engraftment by lymphoid but not erythroid stem cells from normal mice
    • Perkins, D. L., Michaelson, J. and Marshak-Rothstein, A., The lpr gene is associated with resistance to engraftment by lymphoid but not erythroid stem cells from normal mice. J. Immunol. 1987. 138: 466-469.
    • (1987) J. Immunol. , vol.138 , pp. 466-469
    • Perkins, D.L.1    Michaelson, J.2    Marshak-Rothstein, A.3


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