Hemodynamic effects of acute hyperglycemia in type 2 diabetic patients

Diabetes Care

Volumn 23, Issue 5, 2000, Pages 658-663

  Marfella, Raffaele ^a,b   Nappo, Francesco ^a   De Angelis, Lorenita ^a   Paolisso, Giuseppe ^a   Tagliamonte, Maria Rosaria ^a   Giugliano, Dario ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b NONE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CATECHOLAMINE; GLUCOSE; GLUTATHIONE; INSULIN; NITRIC OXIDE; OCTREOTIDE;

ARTICLE; CATECHOLAMINE BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; GLUCOSE CLAMP TECHNIQUE; HEART RATE; HEMODYNAMICS; HUMAN; HYPERGLYCEMIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PRESSORECEPTOR REFLEX; SYSTOLIC BLOOD PRESSURE;

EID: 0034074629     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.23.5.658     Document Type: Article

References (26)

1. DCCT Research Group: The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986, 1993
2. Kuusisto J, Mikkänen L, Pyórälä K, Laakso M: NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes 43:960-967, 1994
3. Bohlen HG, Lash JM: Topical hyperglycemia rapidly suppresses EDRF-mediated vasodilation in normal rat arterioles. Am J Physiol 265:H219-H225, 1993
4. Hollenbaugh DC, Pavek TJ, Crampton MJ, Laxoson DD: Hyperglycemia impairs coronary microvascular endothelium dependent vasodilation (Abstract). Circulation 92 (Suppl. 1):1-451, 1995
5. Bucala R, Tracey KJ, Cerami A: Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes. J Clin Invest 87:432-438, 1991
6. Marfella R, Verrazzo G, Acampora R, La Marca C, Giunta R, Lucarelli C, Paolisso G, Ceriello A, Giugliano D: Glutathione reverses systemic hemodynamic changes induced by hyperglycemia in healthy subjects. Am J Physiol 268:E1167-E1173, 1995
7. Giugliano D, Marfella R, Coppola L, Verrazzo G, Acampora R, Giunta R, Nappo F, Lucarelli C, D'Onofrio F: Vascular effects of acute hyperglycemia in humans are reversed by L-arginine: evidence for reduced availability of nitric oxide during hyperglycemia. Circulation 95:1783-1790, 1997
8. Pieper GM: Review of alteration in endothelial nitric oxide production in diabetes. Hypertension 31:1047-1060, 1998
9. Ceriello A: The emerging role of post-prandial spikes in the pathogenesis of diabetic complications. Diabet Med 15:188-193, 1998
10. Baron AD: Hemodynamic actions of insulin. Am J Physiol 267:E187-E202, 1994
11. Pei D, Jones CN, Bhargava YD, Chen I, Reaven GM: Evaluation of octreotide to assess insulin-mediated glucose disposal by the insulin suppression test. Diabetologia 37:843-845, 1994
12. Parati G, Casadei A, Groppelli M, Di Rienzo M, Mancia G: Comparison of finger and intra-arterial blood pressure monitoring at rest and during laboratory testing. Hypertension 13:647-655, 1989
13. Marfella R, Giugliano D, Di Maro G, Acampora R, Giunta R, D'Onofrio F: The squatting test: a useful tool to assess both parasympathetic and sympathetic involvement of the cardiovascular autonomic neuropathy in diabetes. Diabetes 43:607-612, 1944
14. Paolisso G, Giugliano D, Scheen AJ, Franchimont P, D'Onofrio F, Lefebvre PJ: Primary role of glucagon release in the effect of beta-endorphin on glucose homeostasis in normal man. Acta Endocrinol 115: 161-169, 1987
15. Cross EC, Holliwell B, Borisch ET, Pryor WA, Ames BN, Saul RL, McCord JM, Harman D: Oxygen radicals and human disease. Ann Intern Med 107:526-545, 1987
16. Tesfamarian B, Cohen RA: Free radicals mediate endothelial cell dysfunction caused by elevated glucose. Am J Physiol 263: H321-H326, 1992
17. Houben AJ, Schafer NC, de Haan CHA, Huvers FC, Slaaf W, de Leeuw W, Nieu Wenhuijzen-Kruseman: The effecfs of 7-hour local hyperglycemia on forearm macro and microcirculatory blood flow and vascular reactivity in healthy man. Diabetologia 37:750-756, 1994
18. Williams SB, Goldfine AB, Timimi FK, Ting HH, Roddy MA, Simonson DC, Creager MA: Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation 97:1695-1701, 1998
19. Giugliano D, Ceriello A, Paolisso G: Oxidative stress and diabetic vascular complication. Diabetes Care 19:257-267, 1996
20. Moncada S, Higgs A: The L-arginine-nitric oxide pathway. N Engl J Med 329:2002-2012, 1993
21. Bode-Boger SM, Boger RH, Creutzig A, Tsikas D, Gutzki FM, Alexander K, Frolich JC: L-Arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects. Clin Sci 87: 303-310, 1994
22. Smulders RA, Stehouwer DA, Olthof CG, van Kamp GJ, Teerlink T, de Vries PM, Donker AJ: Plasma endothelin levels and vascular effects of intravenous L-arginine infusion in subjects with uncomplicated insulin-dependent diabetes mellitus. Clin Sci 87:37-43, 1994
23. Kharitonov SA, Lubec G, Lubec B, Hjelm M, Barnes PJ: L-Arginine increases exhaled nitric oxide in normal human subjects. Clin Sci 88:135-139, 1995
24. Rees DD, Palmer RM, Schulz R, Hodson HF, Moncada S: Characterization of three inhibitors of endothelium nitric oxide synthase in vitro and in vivo. Br J Pharmacol 101:746-752, 1990
25. White MF: The transport of cationic amino acids across the plasma membrane of mammalian cells. Biochim Biophys Acta 822:355-374, 1985
26. Giugliano D, Marfella R, Coppola L, Verrazzo G, Acampora R, Coppola L, Cozzolino D, D'Onofrio F: The vascular effects of L-arginine in humans: the role of endogenous insulin. J Clin Invest 99:433-438, 1997