메뉴 건너뛰기




Volumn 57, Issue 4, 2000, Pages 805-810

A molecularly identified P2Y receptor simultaneously activates phospholipase C and inhibits adenylyl cyclase and is nonselectively activated by all nucleoside triphosphates

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE CYCLASE; CYCLIC AMP; CYTIDINE TRIPHOSPHATE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; NUCLEOSIDE TRIPHOSPHATE; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE; XANTHOSINE 5' TRIPHOSPHATE;

EID: 0034074488     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.57.4.805     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 0030852425 scopus 로고    scopus 로고
    • Potential signalling roles for UTP and UDP: Sources, regulation and release of uracil nucleotides
    • Anderson CM and Parkinson FE (1997) Potential signalling roles for UTP and UDP: Sources, regulation and release of uracil nucleotides. Trends Pharmacol Sci 18: 387-392.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 387-392
    • Anderson, C.M.1    Parkinson, F.E.2
  • 2
    • 0030974128 scopus 로고    scopus 로고
    • Early expression of a novel nucleotide receptor in the neural plate of Xenopus embryos
    • Bogdanov YD, Dale L, King BF, Whittock N and Burnstock G (1997) Early expression of a novel nucleotide receptor in the neural plate of Xenopus embryos. J Biol Chem 272:12583-12590.
    • (1997) J Biol Chem , vol.272 , pp. 12583-12590
    • Bogdanov, Y.D.1    Dale, L.2    King, B.F.3    Whittock, N.4    Burnstock, G.5
  • 8
    • 0031466317 scopus 로고    scopus 로고
    • Molecular cloning and expression of an avian G-protein coupled P2Y receptor
    • Boyer JL, Waldo GL and Harden TK (1997) Molecular cloning and expression of an avian G-protein coupled P2Y receptor. Mol Pharmacol 52:928-934.
    • (1997) Mol Pharmacol , vol.52 , pp. 928-934
    • Boyer, J.L.1    Waldo, G.L.2    Harden, T.K.3
  • 10
    • 0031437421 scopus 로고    scopus 로고
    • Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase
    • Communi D, Govaerts C, Parmentier M and Boeynaems J-M (1997) Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase. J Biol Chem 272:31969-31973.
    • (1997) J Biol Chem , vol.272 , pp. 31969-31973
    • Communi, D.1    Govaerts, C.2    Parmentier, M.3    Boeynaems, J.-M.4
  • 11
    • 0031807760 scopus 로고    scopus 로고
    • Ecto-nucleotidases in isolated intact rat vagi, nodose ganglia, and superior cervical ganglia
    • Connolly GP, Demaine C and Duley JA (1998) Ecto-nucleotidases in isolated intact rat vagi, nodose ganglia, and superior cervical ganglia. Adv Exp Med Biol 431: 769-776.
    • (1998) Adv Exp Med Biol , vol.431 , pp. 769-776
    • Connolly, G.P.1    Demaine, C.2    Duley, J.A.3
  • 12
    • 0018804588 scopus 로고
    • ADP is a potent inhibitor of human platelet plasma membrane adenylate cyclase
    • Cooper DMF and Rodbell M (1979) ADP is a potent inhibitor of human platelet plasma membrane adenylate cyclase. Nature (Lond) 282:517-518.
    • (1979) Nature (Lond) , vol.282 , pp. 517-518
    • Cooper, D.M.F.1    Rodbell, M.2
  • 13
    • 0031914973 scopus 로고    scopus 로고
    • Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets
    • Daniel JL, Dangelmaier C, Jin J, Ashby B, Smith JB and Kunapuli SP (1998) Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets. J Biol Chem 273:2024-2029.
    • (1998) J Biol Chem , vol.273 , pp. 2024-2029
    • Daniel, J.L.1    Dangelmaier, C.2    Jin, J.3    Ashby, B.4    Smith, J.B.5    Kunapuli, S.P.6
  • 14
    • 0028177967 scopus 로고
    • The increase in the intracellular Ca2+ concentration induced by mechanical stimulation is propagated via release of pyrophosphorylated nucleotides in mammary epithelial cells
    • Enomoto K, Furuya K, Yamagishi S, Oka T and Maeno T (1994) The increase in the intracellular Ca2+ concentration induced by mechanical stimulation is propagated via release of pyrophosphorylated nucleotides in mammary epithelial cells. Pflugers Arch 427:533-542.
    • (1994) Pflugers Arch , vol.427 , pp. 533-542
    • Enomoto, K.1    Furuya, K.2    Yamagishi, S.3    Oka, T.4    Maeno, T.5
  • 17
    • 0000815257 scopus 로고
    • Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets
    • Gaarder A, Jonsen A, Laland S, Hellem AJ and Owen P (1961) Adenosine diphosphate in red cells as a factor in the adhesiveness of human blood platelets. Nature (Lond) 192:531-532.
    • (1961) Nature (Lond) , vol.192 , pp. 531-532
    • Gaarder, A.1    Jonsen, A.2    Laland, S.3    Hellem, A.J.4    Owen, P.5
  • 18
    • 0021895138 scopus 로고
    • 2+ indicators with greatly improved fluorescence properties
    • 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
    • (1985) J Biol Chem , vol.260 , pp. 3440-3450
    • Grynkiewicz, G.1    Poenie, M.2    Tsien, R.Y.3
  • 20
    • 0031081539 scopus 로고    scopus 로고
    • Release, metabolism and interconversion of adenine and uridine nucleotides: Implications for G protein-coupled P2 receptor agonist selectivity
    • Harden TK, Lazarowski ER and Boucher RC (1997) Release, metabolism and interconversion of adenine and uridine nucleotides: Implications for G protein-coupled P2 receptor agonist selectivity. Trends Pharmacol Sci 18:43-46.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 43-46
    • Harden, T.K.1    Lazarowski, E.R.2    Boucher, R.C.3
  • 21
    • 0020049863 scopus 로고
    • Differential modification of the interaction of cardiac muscarinic cholinergic and β-adrenergic receptors with a guanine nucleotide binding component(s)
    • Harden TK, Scheer AG and Smith MM (1982) Differential modification of the interaction of cardiac muscarinic cholinergic and β-adrenergic receptors with a guanine nucleotide binding component(s). Mol Pharmacol 21:570-580.
    • (1982) Mol Pharmacol , vol.21 , pp. 570-580
    • Harden, T.K.1    Scheer, A.G.2    Smith, M.M.3
  • 22
    • 0025952271 scopus 로고
    • Pharmacological receptors on blood platelets
    • Hourani SMO and Cusack NJ (1991) Pharmacological receptors on blood platelets. Pharmacol Rev 43:243-298.
    • (1991) Pharmacol Rev , vol.43 , pp. 243-298
    • Hourani, S.M.O.1    Cusack, N.J.2
  • 25
    • 0032415306 scopus 로고    scopus 로고
    • Metabotropic receptors for ATP and UTP: Exploring the correspondence between native and recombinant nucleotide receptors
    • King BF, Townsend-Nicholson A and Burnstock G (1998) Metabotropic receptors for ATP and UTP: Exploring the correspondence between native and recombinant nucleotide receptors. Trends Pharmacol Sci 19:506-514.
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 506-514
    • King, B.F.1    Townsend-Nicholson, A.2    Burnstock, G.3
  • 26
    • 0032803745 scopus 로고    scopus 로고
    • Quantitaten of extracellular UTP using a sensitive enzymatic assay
    • Lazarowski ER and Harden TK (1999) Quantitaten of extracellular UTP using a sensitive enzymatic assay. Br J Pharmacol 127:1272-1278.
    • (1999) Br J Pharmacol , vol.127 , pp. 1272-1278
    • Lazarowski, E.R.1    Harden, T.K.2
  • 27
    • 0030882314 scopus 로고    scopus 로고
    • Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation
    • Lazarowski ER, Homolya L, Boucher RC and Harden TK (1997) Direct demonstration of mechanically induced release of cellular UTP and its implication for uridine nucleotide receptor activation. J Biol Chem 272:24348-24354.
    • (1997) J Biol Chem , vol.272 , pp. 24348-24354
    • Lazarowski, E.R.1    Homolya, L.2    Boucher, R.C.3    Harden, T.K.4
  • 28
    • 0018831729 scopus 로고
    • Inhibition of platelet adenylate cyclase by ADP
    • Mellwig KP and Jakobs KH (1980) Inhibition of platelet adenylate cyclase by ADP. Thromb Res 18:7-17.
    • (1980) Thromb Res , vol.18 , pp. 7-17
    • Mellwig, K.P.1    Jakobs, K.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.