Monoclonal antibodies directed against the T-cell activation molecule CD137 (interleukin-A or 4-1BB) block human lymphocyte-mediated suppression of tumor xenografts in severe combined immunodeficient mice

Journal of Immunotherapy

Volumn 23, Issue 3, 2000, Pages 362-368

  Sabel, Michael S ^a   Conway, Thomas F ^a   Chen, Fang An ^a   Bankert, Richard B ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

4 1BB; CD137; Human tumor xenografts; Interleukin A Lymphocyte dependent tumor immunity Mixed lymphocyte reaction; SCID mice; SCID Winn assay; T cell activation antigen

Indexed keywords

INTERLEUKIN 4; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER IMMUNOTHERAPY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; T LYMPHOCYTE ACTIVATION; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR XENOGRAFT;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD137; ANTIGENS, CD4; ANTIGENS, CD8; DENDRITIC CELLS; HUMANS; ISOANTIGENS; LUNG NEOPLASMS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; LYMPHOCYTES; MICE; NEOPLASM TRANSPLANTATION; RECEPTORS, NERVE GROWTH FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR; SEVERE COMBINED IMMUNODEFICIENCY; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0034074135     PISSN: 10538550     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002371-200005000-00009     Document Type: Article

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