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10 Silverman K, Chutuape MA, Bigelow GE, Stitzer ML. Voucher-based reinforcement of cocaine abstinence in treatment-resistant methadone patients: effects of reinforcement magnitude. Psychopharmacology (Berl) 1999; 146:128-138. This study demonstrated that cocaine abstinence among treatment-resistant cocaine-abusing heroin addicts can be increased by increasing the value of vouchers used in a voucher-based contingency management therapy. Reinforcement magnitude was a critical determinant of the effectiveness of this abstinence reinforcement intervention.
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21 Kidorf M, Hollander JR, King VL, Brooner RK. Increasing employment of opioid dependent outpatients: an intensive behavioral intervention. Drug Alcohol Depend 1998; 50:73-60. This study evaluated the success of a new treatment requirement that patients who had been maintained on methadone for 12 months gain employment (20 h/week, paid or volunteer) using a behavioral contingency paradigm. Of the patients 75% secured employment and maintained the position for at least 1 month. Most patients (78%) continued working throughout the 6-month follow up. These results demonstrate that behavioral contingencies can motivate many methadone maintenance patients to obtain employment.
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23 Fischer G, Gombas W, Eder H, Jagsch R, Peternell A, Stuhlinger G, et al. Buprenorphine versus methadone maintenance for the treatment of opioid dependence. Addiction 1999; 94:1337-1347. This report describes an open study that compared the efficacy of buprenorphine versus methadone in 60 opiate addicts over a 24-week period. Both drugs were effective for some patients. The retention rate was significantly better in the methadone maintained group, however, whereas those in the buprenorphine group had significantly lower rates of illicit opiate consumption.
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