Deactivation of cultured human liver myofibroblasts by trans- resveratrol, a grapevine-derived polyphenol

Hepatology

Volumn 31, Issue 4, 2000, Pages 922-931

  Godihaud, Sandrine ^a   Krisa, Stéphanie ^b   Couronné, Baptiste ^a   Dubuisson, Liliane ^a   Mérillon, Jean Michel ^b   Desmoulière, Alexis ^a   Rosenbaum, Jean ^a  

^a INSERM   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; BETA ACTIN; COLLAGEN TYPE 1; GELATINASE A; MESSENGER RNA; PICEATANOL; PICEID; POLYPHENOL DERIVATIVE; RESVERATROL; STILBENE DERIVATIVE; UNCLASSIFIED DRUG; VIMENTIN;

ARTICLE; CANCER INHIBITION; CELL ACTIVATION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME RELEASE; FIBROGENESIS; HUMAN; HUMAN CELL; LIVER CARCINOMA; LIVER CELL; LIVER FIBROSIS; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0034065342     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/he.2000.5848     Document Type: Article

References (32)

1. Milani S, Herbst H, Schuppan D, Surrenti C, Riecken EO, Stein H. Cellular localization of type I, III, and IV procollagen gene transcripts in normal and fibrotic human liver. Am J Pathol 1990;137:59-70.
2. Friedman SL. The cellular basis of hepatic fibrosis. Mechanisms and treatment strategies. N Engl J Med 1993;328:1828-1835.
3. Desmoulière A, Darby I, Costa AMA, Raccurt M, Tuchweber B, Sommer P, Gabbiani G. Extracellular matrix deposition, lysyl oxidase expression, and myofibroblastic differentiation during the initial stages of cholestatic fibrosis in the rat. Lab Invest 1997;76:765-778.
4. Enzan H, Himeno H, Iwamura S, Saibara T, Yamamoto Y, Hara H. α-Smooth muscle actin-positive perisinusoidal stromal cells in human hepatocellular carcinoma. HEPATOLOGY 1994;19:895-903.
5. Terada T, Makimoto K, Terayama N, Suziki Y, Nakanuma Y. Alpha-smooth muscle actin-positive stromal cells in cholangiocarcinomas, hepatocellular carcinomas and metastatic liver carcinomas. J Hepatol 1996;24:706-712.
6. Faouzi S, Le Bail B, Neaud V, Boussarie L, Saric J, Bioulac-Sage P, Balabaud C, et al. Myofibroblasts are responsible for collagen synthesis in the stroma of human hepatocellular carcinoma: an in vivo and in vitro study. J Hepatol 1999;30:275-284.
7. Mérillon JM, Fauconneau B, Waffo Teguo P, Barrier L, Vercauteren J, Huguet F. Antioxidant activity of the stilbene astringin, newly extracted from vitis vinifera cell cultures. Clin Chem 1997;43:1092-1093.
8. Waffo Teguo P, Fauconneau B, Deffieux G, Huguet F, Vercauteren J, Mérillon JM. Isolation, identification, and antioxidant activity of three stilbene glucosides newly extracted from Vitis vinifera cell cultures. J Nat Prod 1998;61:655-657.
9. Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implication for protection against coronary heart disease. Clin Chim Acta 1995;235:207-219.
10. Jang M, Cai M, Udeani GO, Slowing KV, Thomas CF, Beecher CWW, Fong HHS, et al. Cancer chemopreventive activity of Resveratrol, a natural product derived from grapes. Science 1997;275:218-219.
11. Win KM, Charlotte F, Mallat A, Cherqui D, Martin N, Mavier P, Préaux AM, et al. Mitogenic effect of transforming growth factor-β1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor. HEPATOLOGY 1993;18:137-145.
12. Blazejewski S, Préaux AM, Mallat A, Brochériou I, Mavier P, Dhumeaux D, Schuppan D, et al. Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver. HEPATOLOGY 1995;22:788-797.
13. Waffo Teguo P, Descendit A, Krisa S, Deffieux G, Vercauteren J, Mérillon JM. The accumulation of stilbene glycosides in vitis vinifera cell suspension cultures. J Nat Prod 1996;59:1189-1191.
14. Labarca C, Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 1980;102:344-352.
15. Herron GS, Banda MJ, Clark EJ, Gavrilovic J, Werb Z. Secretion of metalloproteinases by stimulated capillary endothelial cells. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors. J Biol Chem 1986;261:2814-2818.
16. Chu ML, de Wet W, Bernard R, Ramirez F. Fine structural analysis of the human pro-α1(I) collagen gene. Promoter structure, AluI repeats and polymorphic transcripts. J Biol Chem 1985;260:2315-2320.
17. Neaud V, Faouzi S, Guirouilh J, Le Bail B, Balabaud C, Bioulac-Sage P, Rosenbaum J. Human hepatic myofibroblasts increase invasiveness of hepatocellular carcinoma cells: evidence for a role of hepatocyte growth factor. HEPATOLOGY 1997;26:1458-1466.
18. Monvoisin A, Neaud V, De Ledinghen V, Dubuisson L, Balabaud C, Bioulac-Sage P, Desmoulière A, et al. Direct evidence that hepatocyte growth factor-induced invasion of hepatocellular carcinoma cells is mediated by urokinase. J Hepatol 1999;30:511-518.
19. Clément MV, Hirpara J, Chawdhury S, Pervaiz S. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood 1998;92:996-1002.
20. Mgbonyebi OP, Russo J, Russo IH. Antiproliferative effect of synthetic resveratrol on human breast epithelial cells. Int J Oncol 1998;12:865-869.
21. Kawada N, Seki S, Inoue M, Kuroki T. Effect of antioxidants, resveratrol, quercetin, and N-acetylcysteine, on the functions of cultured rat hepatic stellate cells and Kupffer cells. HEPATOLOGY 1998;27:1265-1274.
22. 2. Cancer Res 1999;59: 2596-2601.
23. Fontecave M, Lepoivre M, Elleingand E, Gerez C, Guittet O. Resveratrol, a remarkable inhibitor of ribonucleotide reductase. FEBS Lett 1998;421: 277-279.
24. Jayatilake GS, Jayasuriya H, Lee ES, Koonchanok NM, Geahlen RL, Ashendel CL, McLaughlin JL, et al. Kinase inhibitors from polygonum cuspidatum. J Nat Prod 1993;56:1805-1810.
25. Wang BH, Lu ZX, Polya GM. Inhibition of eukaryote serine/threonine-specific protein kinases by piceatannol. Planta Med 1998;64:195-199.
26. Liang YC, Lin-shiau SY, Chen CF, Lin JK. Suppression of extracellular signal and cell proliferation through EGF receptor binding by (-)epigallocatechin gallate in human A431 epidermoid carcinoma cells. J Cell Biochem 1997;67:55-65.
27. Marra F, Gentilini A, Pinzani M, Choudhury GG, Parola M, Herbst H, Dianzani MU, et al. Phosphatidylinositol 3-kinase is required for platelet-derived growth factor's actions on hepatic stellate cells. Gastroenterology 1997;112:1297-1306.
28. Agullo G, Gamet-Payrastre L, Manenti S, Viala C, Rémésy C, Chap H, Payrastre B. Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition. Biochem Pharmacol 1997;53:1649-1657.
29. Mallat A, Préaux AM, Blazejewski S, Rosenbaum J, Dhumeaux D, Mavier P. Interferon alfa and gamma inhibit proliferation and collagen synthesis of human Ito cells in culture. HEPATOLOGY 1995;21:1003-1010.
30. Préaux AM, Mallat A, Rosenbaum J, Zafrani ES, Mavier P. Pentoxifylline inhibits growth and collagen synthesis of cultured human hepatic myofibroblast-like cells. HEPATOLOGY 1997;26:315-321.
31. Juan M, Lamuela-Raventos RM, De la Torre-Boronat MC, Planas JM. Determination of trans-resveratrol in plasma by HPLC. Anal Chem 1999;71:747-750.
32. Bertelli AAE, Giovannini L, Stradi R, Bertelli A, Tillement JP. Plasma, urine and tissue levels of trans and cis-resveratrol (3,4′,5-trihydroxystilbene) after short-term or prolonged administration of red wine to rats. Int J Tiss React 1996;18:67-71.