Chronic Effects of the Novel Glucocorticosteroid RPR 106541 Administered to Beagle Dogs by Inhalation

Toxicologic Pathology

Volumn 28, Issue 2, 2000, Pages 226-236

  Miller, Glen K ^a   Valerio, Marion G ^a   Pino, Michael V ^a   Larson, Jeffrey L ^b   Viau, André ^b   Hamelin, Nicole ^b   Labbé, Raymond ^b   Banks, Christopher M ^b  

^a SANOFI   (France)

^b ClinTrials BioResearch Ltd   (Canada)

Author keywords

adrenocortical atrophy; dogs; dry powder formulation; glucocorticosteroids; Inhalation toxicity; metered dose inhaler; reproductive toxicity

Indexed keywords

17 THIOSTEROID DERIVATIVE; GLUCOCORTICOID; RPR 106541; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ASTHMA; DOG; DRUG EFFECT; DRUG FORMULATION; DRUG SAFETY; ENDOMETRIUM HYPERPLASIA; METERED DOSE INHALER; NONHUMAN; OSTEOLYSIS; OVARY FOLLICLE ATRESIA; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE;

ADMINISTRATION, INHALATION; ADRENAL GLANDS; AEROSOLS; ANDROSTENES; ANIMALS; ANTI-ASTHMATIC AGENTS; BODY WEIGHT; BONE MARROW; CLINICAL CHEMISTRY TESTS; DOGS; FEMALE; FEMUR; GONADS; LIVER; LYMPHOID TISSUE; MALE; MAMMARY GLANDS, ANIMAL; NEBULIZERS AND VAPORIZERS; ORGAN SIZE; POWDERS; STERNUM;

ANIMALIA; CANIS FAMILIARIS;

EID: 0034062590     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262330002800202     Document Type: Article

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