The SH2D2A gene encoding the T-cell-specific adapter protein (TSAd) is localized centromeric to the CD1 gene cluster on human Chromosome 1

Immunogenetics

Volumn 51, Issue 3, 2000, Pages 179-185

  Dai, Ke Zheng ^a   Vergnaud, Gilles ^b   Ando, Asako ^c   Inoko, Hidetoshi ^c   Spurkland, Anne ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adapter protein; Alternative splicing; Linkage analysis; SH2D2A gene; Single nucleotide polymorphism

Indexed keywords

ADAPTOR PROTEIN; CONTIG; DNA; DNA MARKER; MESSENGER RNA;

ARTICLE; CENTROMERE; CHROMOSOME 1Q; COSMID; DNA LIBRARY; DNA POLYMORPHISM; EXON; GENE CLUSTER; GENE ISOLATION; GENE MAPPING; GENETIC LINKAGE; HUMAN; INTRON; MOLECULAR CLONING; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 0034058716     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050029     Document Type: Article

References (23)

1. Antalis TM, Costelloe E, Muddiman J, Ogbourne S, Donnan K (1996) Regulation of the plasminogen activator inhibitor type-2 gene in monocytes: localization of an upstream transcriptional silencer. Blood 88:3686-3697
2. Antonarakis SE (1998) Recommendations for a nomenclature system for human gene mutations. Nomenclature Working Group. Hum Mutat 11:1-3
3. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (1994) Preparation and analysis of RNA. In: Current protocols in molecular biology. Current Protocols, Greene/Wiley, New York, pp 4.7.1-4.7.8
4. Birge RB, Knudsen BS, Besser D, Hanafusa H (1996) SH2- and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction. Genes Cells 1:595-613
5. Chen Y, Gill GN (1996) A heterodimeric nuclear protein complex binds two palindromic sequences in the proximal enhancer of the human erbB-2 gene. J Biol Chem 271:5183-5188
6. Crabtree GR, Clipstone NA (1994) Signal transmission between the plasma membrane and nucleus of T lymphocytes. Annu Rev Biochem 63:1045-1083
7. Dib C, Faure S, Fizames C, Samson D, Drouot N, Vignal A, Millasseau P, Marc S, Kazan J, Seboun E, Lathrop M, Gyapay G, Morissette J, Weissenbach J (1996) A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 380:152-154
8. Eck MJ, Shoelson SE, Harrison SC (1993) Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p561ck. Nature 362:87-91
9. Endo T, Imanishi T, Gojobori T, Inoko H (1997) Evolutionary significance of intra-genome duplications on human chromosomes. Gene 205:19-27
10. Heinemeyer T, Wingender E, Reuter I, Hermjakob H, Kel AE, Kel OV, Ignatieva EV, Ananko EA, Podkolodnaya OA, Kolpakov FA, Podkolodny NL, Kolchanov NA (1998) Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res 26:362-367
11. Inoko H, Shigenari A, Suto Y, Kawata H, Shiina T, Soeda E, Sugaya K, Tokunaga K, Ikemura T, Ando A (1998) Gene organization of human chromosome Iq22-q23 region which is homologous to the HLA region on chromosome 6p21.3 (abstract). Cytogenet Cell Genet 83:147-175
12. Kim S-J, Onwuta US, Lee YI, Li R, Botchan MR, Robbins PD (1992) The retinoblastoma gene product regulates Sp1-mediated transcription. Mol Cell Biol 12:2455-2463
13. Körner K, Wolfraim LA, Lucibello FC, Muller R (1997) Characterization of the TATA-less core promoter of the cell cycle-regulated cdc25°C gene. Nucleic Acids Res 25:4933-4939
14. Kruglyak L (1997) The use of a genetic map of biallelic markers in linkage studies. Nat Genet 17:21-24
15. Osoegawa K, Susukida R, Okano S, Kudoh J, Minoshima S, Shimizu N, Jong PJ de, Groet J, Ives J, Lehrach H, Nizetic D, Soeda E (1996) An integrated map with cosmid/PAC contigs of a 4-Mb Down syndrome critical region. Genomics 32:375-387
16. Pandey A, Duan H, Dixit VM (1995) Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase. J Biol Chem 270:19201-19204
17. Park JH, Lee HW, Fleischhauer KL, Kim CG, Sheffery M, Yang SY (1993) DNA-binding proteins for transcription enhancing region of HLA class I gene. Tissue Antigens 42:78-86
18. Risch N, Merikangas K (1996) The future of genetic studies of complex human diseases. Science 273:1516-1517
19. Rudd CE (1998) Lymphocyte signaling: adapting new adaptors. Curr Biol 8:805-808
20. Spurkland A, Brinchmann JE, Markussen G, Pedeutour F, Munthe E, Lea T, Vartdal F, Aasheim HC (1998) Molecular cloning of a T cell-specific adapter protein (TSAd) containing an Src homology (SH) 2 domain and putative SH3 and phosphotyrosine binding sites. J Biol Chem 273:4539-4546
21. Strachan T, Read AP (1996) Genetic mapping. In: Human molecular genetics. Bios, Oxford UK, pp 318-334
22. Sugaya K, Fukagawa T, Matsumoto K, Mita K, Takahashi E, Ando A, Inoko H, Ikemura T (1994) Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3. Genomics 23:408-419
23. Sugaya K, Sasanuma S, Nohata J, Kimura T, Fukagawa T, Nakamura Y, Ando A, Inoko H, Ikemura T, Mita K (1997) Gene organization of human NOTCH4 and (CTG)n polymorphism in this human counterpart gene of mouse proto-oncogene Int3. Gene 189:235-244