Release of GM-CSF and G-CSF by human arterial and venous smooth muscle cells: Differential regulation by COX-2

British Journal of Pharmacology

Volumn 129, Issue 5, 2000, Pages 835-838

  Stanford, Salome J ^a   Pepper, John R ^a   Mitchell, Jane A ^a  

^a ROYAL BROMPTON AND HAREFIELD NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Cyclo oxygenase 2; G CSF; GM CSF; Prostacyclin; Smooth muscle cells

Indexed keywords

CICAPROST; COLONY STIMULATING FACTOR; CYCLOOXYGENASE 2; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INDOMETACIN; PROSTACYCLIN; PROSTAGLANDIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INDUCTION; HUMAN; HUMAN CELL; INFLAMMATION; MEDIATOR RELEASE; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; VASCULAR SMOOTH MUSCLE;

EID: 0034057080     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703151     Document Type: Article

References (15)

1. 2 enhances interleukin-8 (IL-8) and IL-6 but inhibits GM-CSF production by IL-1 stimulated human synovial fibroblasts in vitro. J. Rheumatol., 23, 862-868.
2. Bishop-Bailey, D., Pepper, J.R., Larkin, S.W. & Mitchell, J.A. (1998). Differential induction of cyclo-oxygenase-2 in human arterial and venous smooth muscle: role of endogenous prostanoids. Arterioslcer. Thromb. Vasc. Biol., 18, 1655-1661.
3. Colotta, F., Re, F., Polentarutti, N., Sozzani, S. & Mantovani, A. (1992). Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products. Blood, 80, 2012-2020.
4. Eischen, A., Vincent, F., Bergerat, J.P., Louis, B., Faradji, A., Bohbot, A. & Oberling, F. (1991). Long term cultures of human monocytes in vitro. Impact of GM-CSF on survival and differentiation. J. Immunol. Methods, 143, 209-221.
5. Erickson-Miller, C.L., Brennan, J.K. & Abboud, C.N. (1990). Examination of survival, proliferation and cell surface antigen expression of human monocytes exposed to macrophage colony-stimulating factor (M-CSF). Int. J. Cell Cloning, 8, 346-356.
6. Hamilton, J.A., Piccoli, D.S., Cebon, J., Layton, J.E., Rathanaswani, P., McColl, S.R. & Leizer, T. (1992). Cytokine regulation of colony-stimulating factor (CSF) production in cultured human synovial fibroblasts. II. Similarities and differences in the control of interleukin-1 induction of granulocyte-macrophage CSF and granulocyte-CSF production. Blood, 79, 1413-1419.
7. Lee, M.T., Kaushanski, K., Ralph, P. & Ladner, M.B. (1990). Differential expression of M-CSF, G-CSF and GM-CSF by human monocytes. J. Leuk. Biol., 47, 275-282.
8. Lopez, A.F., Williamson, D.J., Gamble, J.R., Begley, C.G., Harlan, J.M., Klebanoff, S.J., Waltersdorph, A., Wong, G., Clark, S.C. & Vadas, M.A. (1986). Recombinant human granulocyte macrophage-colony stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression and survival. J. Clin. Invest., 78, 1220-1228.
9. Luttmann, W., Herzog, V., Virchow, J.C., Matthys, H., Thierauch, K.H. & Kroegel, C. (1996). Prostacyclin modulates granulocyte, macrophage colony-stimulating factor release by human blood mononuclear cells. Pulm. Pharmacol., 9, 43-48.
10. Metcalf, D. (1986). The molecular biology and functions of the granulocyte-macrophage colony stimulating factors. Blood, 67, 257-267.
11. Mitchell, J.A., Akarasereenont, P., Thiemermann, C., Flower, R.J. & Vane, J.R. (1993). Selectivity of nonsteroidal anti-inflammatory drugs as inhibitors of constitutive and inducible cyclo-oxygenase. Proc. Natl. Acad. Sci. U.S.A., 90, 11693-11697.
12. Mitchell, J.A. & Warner, T.D. (1999). Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br. J. Pharmacol., 128, 1121-1132.
13. Stanford, S.J., Pepper, J.R. & Mitchell, J.A. (2000). Cyclo-oxygenase-2 regulates Granulocyte macrophage-colony stimulating factor, but not interleukin-8, production by human vascular cells: role of cyclic AMP. Arterioscler. Thromb. Vasc. Biol., In press.
14. Warner, T.D., Giuliano, F., Vojnovic, I., Bukasa, A., Mitchell, J.A. & Vane, J.R. (1999). Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc. Natl. Acad. Sci. U.S.A., 96, 7563-7568.
15. Zoellner, H., Filonzi, E.L., Stanton, H.R., Layton, J.E. & Hamilton, J.A. (1992). Human arterial smooth muscle cells synthesise granulocyte colony-stimulating factor in response to interleukin-1 alpha and tumour necrosis factor-alpha. Blood, 80, 2805-2810.