메뉴 건너뛰기




Volumn 98, Issue 4, 2000, Pages 793-800

Mechano-insensitive nociceptors encode pain evoked by tonic pressure to human skin

Author keywords

Anti inflammatory analgesics; C fiber; Microneurography; Polymodal nociceptor; Psychophysics; Static mechanical hyperalgesia

Indexed keywords

CAPSAICIN;

EID: 0034053632     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00189-5     Document Type: Article
Times cited : (104)

References (40)
  • 1
    • 0021207111 scopus 로고
    • Nociceptor discharges and sensations due to prolonged noxious mechanical stimulation - A paradox
    • Adriaensen H., Gybels J., Handwerker H.O., Van Hees J. Nociceptor discharges and sensations due to prolonged noxious mechanical stimulation - a paradox. Hum. Neurobiol. 3:1984;53-58.
    • (1984) Hum. Neurobiol. , vol.3 , pp. 53-58
    • Adriaensen, H.1    Gybels, J.2    Handwerker, H.O.3    Van Hees, J.4
  • 2
    • 0032719392 scopus 로고    scopus 로고
    • Peripheral coding of tonic mechanical cutaneous pain: Comparison of nociceptor activity in rat and human psychophysics
    • Andrew D., Greenspan J.D. Peripheral coding of tonic mechanical cutaneous pain: comparison of nociceptor activity in rat and human psychophysics. J. Neurophysiol. 82:1999;2641-2648.
    • (1999) J. Neurophysiol. , vol.82 , pp. 2641-2648
    • Andrew, D.1    Greenspan, J.D.2
  • 3
    • 0015950370 scopus 로고
    • Nervous outflow from the cat's foot during noxious radiant heat stimulation
    • Beck P.W., Handwerker H.O., Zimmermann M. Nervous outflow from the cat's foot during noxious radiant heat stimulation. Brain Res. 67:1974;373-386.
    • (1974) Brain Res. , vol.67 , pp. 373-386
    • Beck, P.W.1    Handwerker, H.O.2    Zimmermann, M.3
  • 4
    • 0032102772 scopus 로고    scopus 로고
    • Effects of antihyperalgesic drugs on experimentally induced hyperalgesia in man
    • Bickel A., Dorfs S., Schmelz M., Forster C., Uhl W., Handwerker H.O. Effects of antihyperalgesic drugs on experimentally induced hyperalgesia in man. Pain. 76:1998;317-325.
    • (1998) Pain , vol.76 , pp. 317-325
    • Bickel, A.1    Dorfs, S.2    Schmelz, M.3    Forster, C.4    Uhl, W.5    Handwerker, H.O.6
  • 5
    • 0023740979 scopus 로고
    • Prolonged noxious mechanical stimulation of the rat's tail: Responses and encoding properties of dorsal horn neurones
    • Cervero F., Handwerker H.O., Laird J.M. Prolonged noxious mechanical stimulation of the rat's tail: responses and encoding properties of dorsal horn neurones. J. Physiol. 404:1988;419-436.
    • (1988) J. Physiol. , vol.404 , pp. 419-436
    • Cervero, F.1    Handwerker, H.O.2    Laird, J.M.3
  • 6
    • 0023894715 scopus 로고
    • Measurement of the analgesic effects of aspirin with a new experimental algesimetric procedure
    • Forster C., Anton F., Reeh P.W., Weber E., Handwerker H.O. Measurement of the analgesic effects of aspirin with a new experimental algesimetric procedure. Pain. 32:1988;215-222.
    • (1988) Pain , vol.32 , pp. 215-222
    • Forster, C.1    Anton, F.2    Reeh, P.W.3    Weber, E.4    Handwerker, H.O.5
  • 7
    • 0025134244 scopus 로고
    • Automatic classification and analysis of microneurographic spike data using a PC/AT
    • Forster C., Handwerker H.O. Automatic classification and analysis of microneurographic spike data using a PC/AT. J. Neurosci. Meth. 31:1990;109-118.
    • (1990) J. Neurosci. Meth. , vol.31 , pp. 109-118
    • Forster, C.1    Handwerker, H.O.2
  • 8
  • 9
    • 0030218982 scopus 로고    scopus 로고
    • Activity-dependent slowing of conduction velocity provides a method for identifying different functional classes of C-fibre in the rat saphenous nerve
    • Gee M.D., Lynn B., Cotsell B. Activity-dependent slowing of conduction velocity provides a method for identifying different functional classes of C-fibre in the rat saphenous nerve. Neuroscience. 73:1996;667-675.
    • (1996) Neuroscience , vol.73 , pp. 667-675
    • Gee, M.D.1    Lynn, B.2    Cotsell, B.3
  • 11
    • 0016327555 scopus 로고
    • Methods to differentiate electrically induced afferent and sympathetic C unit responses in human cutaneous nerves
    • Hallin R.G., Torebjörk H.E. Methods to differentiate electrically induced afferent and sympathetic C unit responses in human cutaneous nerves. Acta physiol. scand. 92:1974;318-331.
    • (1974) Acta Physiol. Scand. , vol.92 , pp. 318-331
    • Hallin, R.G.1    Torebjörk, H.E.2
  • 12
    • 0016359140 scopus 로고
    • Single unit sympathetic activity in human skin nerves during rest and various manoeuvres
    • Hallin R.G., Torebjörk H.E. Single unit sympathetic activity in human skin nerves during rest and various manoeuvres. Acta physiol. scand. 92:1974;303-317.
    • (1974) Acta Physiol. Scand. , vol.92 , pp. 303-317
    • Hallin, R.G.1    Torebjörk, H.E.2
  • 13
    • 0023127240 scopus 로고
    • Discharge patterns of afferent cutaneous nerve fibers from the rat's tail during prolonged noxious mechanical stimulation
    • Handwerker H.O., Anton F., Reeh P.W. Discharge patterns of afferent cutaneous nerve fibers from the rat's tail during prolonged noxious mechanical stimulation. Expl Brain Res. 65:1987;493-504.
    • (1987) Expl Brain Res. , vol.65 , pp. 493-504
    • Handwerker, H.O.1    Anton, F.2    Reeh, P.W.3
  • 15
    • 0029146939 scopus 로고
    • Inflammatory models of cutaneous hyperalgesia are sensitive to effects of ibuprofen in man
    • Kilo S., Forster C., Geisslinger G., Brune K., Handwerker H.O. Inflammatory models of cutaneous hyperalgesia are sensitive to effects of ibuprofen in man. Pain. 62:1995;187-193.
    • (1995) Pain , vol.62 , pp. 187-193
    • Kilo, S.1    Forster, C.2    Geisslinger, G.3    Brune, K.4    Handwerker, H.O.5
  • 16
    • 0025907656 scopus 로고
    • A novel technique for the evaluation of mechanical pain and hyperalgesia
    • Kohllöffel L.U.E., Koltzenburg M., Handwerker H.O. A novel technique for the evaluation of mechanical pain and hyperalgesia. Pain. 46:1991;81-87.
    • (1991) Pain , vol.46 , pp. 81-87
    • Kohllöffel, L.U.E.1    Koltzenburg, M.2    Handwerker, H.O.3
  • 17
    • 0028262934 scopus 로고
    • Differential ability of human cutaneous nociceptors to signal mechanical pain and to produce vasodilatation
    • Koltzenburg M., Handwerker H.O. Differential ability of human cutaneous nociceptors to signal mechanical pain and to produce vasodilatation. J. Neurosci. 14:1994;1756-1765.
    • (1994) J. Neurosci. , vol.14 , pp. 1756-1765
    • Koltzenburg, M.1    Handwerker, H.O.2
  • 18
    • 0032421304 scopus 로고    scopus 로고
    • Low-dose lidocaine suppresses experimentally induced hyperalgesia in humans
    • Koppert W., Zeck S., Sittl R., Likar R., Knoll R., Schmelz M. Low-dose lidocaine suppresses experimentally induced hyperalgesia in humans. Anesthesiology. 89:1998;1345-1353.
    • (1998) Anesthesiology , vol.89 , pp. 1345-1353
    • Koppert, W.1    Zeck, S.2    Sittl, R.3    Likar, R.4    Knoll, R.5    Schmelz, M.6
  • 19
    • 0021258972 scopus 로고
    • Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: A comparison with C-fiber nociceptor activities in monkey and human
    • LaMotte R.H., Torebjörk H.E., Robinson C.J., Thalhammer J.G. Time-intensity profiles of cutaneous pain in normal and hyperalgesic skin: a comparison with C-fiber nociceptor activities in monkey and human. J. Neurophysiol. 51:1984;1434-1450.
    • (1984) J. Neurophysiol. , vol.51 , pp. 1434-1450
    • Lamotte, R.H.1    Torebjörk, H.E.2    Robinson, C.J.3    Thalhammer, J.G.4
  • 20
    • 0025005964 scopus 로고
    • Pain and vascular reflexes in man elicited by prolonged noxious mechano-stimulation
    • Magerl W., Geldner G., Handwerker H.O. Pain and vascular reflexes in man elicited by prolonged noxious mechano-stimulation. Pain. 43:1990;219-225.
    • (1990) Pain , vol.43 , pp. 219-225
    • Magerl, W.1    Geldner, G.2    Handwerker, H.O.3
  • 21
    • 0001895691 scopus 로고
    • Responses of dorsal cord cells to peripheral cutaneous unmyelinated fibres
    • Mendell L.M., Wall P.D. Responses of dorsal cord cells to peripheral cutaneous unmyelinated fibres. Nature, Lond. 206:1965;97-99.
    • (1965) Nature, Lond. , vol.206 , pp. 97-99
    • Mendell, L.M.1    Wall, P.D.2
  • 22
    • 84960959252 scopus 로고
    • A method for the measurement of analgesic activity on inflamed tissue
    • Randall L.O., Selitto J.J. A method for the measurement of analgesic activity on inflamed tissue. Archs int. Pharmacodyn. Ther. 3:1957;409-419.
    • (1957) Archs Int. Pharmacodyn. Ther. , vol.3 , pp. 409-419
    • Randall, L.O.1    Selitto, J.J.2
  • 23
    • 0023127241 scopus 로고
    • Sensitization of nociceptive cutaneous nerve fibres from the rat's tail by noxious mechanical stimulation
    • Reeh P.W., Bayer J., Kocher L., Handwerker H.O. Sensitization of nociceptive cutaneous nerve fibres from the rat's tail by noxious mechanical stimulation. Expl Brain Res. 65:1987;505-512.
    • (1987) Expl Brain Res. , vol.65 , pp. 505-512
    • Reeh, P.W.1    Bayer, J.2    Kocher, L.3    Handwerker, H.O.4
  • 24
    • 0020553173 scopus 로고
    • Psychophysical detection and pain ratings of incremental thermal stimuli: A comparison with nociceptor responses in humans
    • Robinson C.J., Torebjörk H.E., LaMotte R.H. Psychophysical detection and pain ratings of incremental thermal stimuli: a comparison with nociceptor responses in humans. Brain Res. 274:1983;87-106.
    • (1983) Brain Res. , vol.274 , pp. 87-106
    • Robinson, C.J.1    Torebjörk, H.E.2    Lamotte, R.H.3
  • 26
    • 0000551698 scopus 로고    scopus 로고
    • Differential sensitivity of mechanosensitive and -insensitive C-fibers in human skin to tonic pressure and capsaicin
    • Schmelz M., Schmidt R., Bickel A., Handwerker H.O., Torebjörk H.E. Differential sensitivity of mechanosensitive and -insensitive C-fibers in human skin to tonic pressure and capsaicin. Soc. Neurosci. Abstr. 23:(Part 1):1997;1004.
    • (1997) Soc. Neurosci. Abstr. , vol.23 , Issue.1 PART , pp. 1004
    • Schmelz, M.1    Schmidt, R.2    Bickel, A.3    Handwerker, H.O.4    Torebjörk, H.E.5
  • 28
    • 0033975763 scopus 로고    scopus 로고
    • Encoding of burning pain from capsaicin treated human skin in two categories of unmyelinated nerve fibers
    • Schmelz M., Schmidt R., Handwerker H.O., Torebjörk H.E. Encoding of burning pain from capsaicin treated human skin in two categories of unmyelinated nerve fibers. Brain. 123:2000;560-571.
    • (2000) Brain , vol.123 , pp. 560-571
    • Schmelz, M.1    Schmidt, R.2    Handwerker, H.O.3    Torebjörk, H.E.4
  • 32
    • 0033559376 scopus 로고    scopus 로고
    • Activity-dependent slowing of conduction differentiates functional subtypes of C fibers innervating human skin
    • Serra J., Campero M., Ochoa J., Bostock H. Activity-dependent slowing of conduction differentiates functional subtypes of C fibers innervating human skin. J. Physiol., Lond. 515:1999;799-811.
    • (1999) J. Physiol., Lond. , vol.515 , pp. 799-811
    • Serra, J.1    Campero, M.2    Ochoa, J.3    Bostock, H.4
  • 33
    • 0028557067 scopus 로고
    • Modality-dependent modulation of conduction by impulse activity in functionally characterized single cutaneous afferents in the rat
    • Thalhammer J.G., Raymond S.A., Popitz B., Strichartz G.R. Modality-dependent modulation of conduction by impulse activity in functionally characterized single cutaneous afferents in the rat. Somatosensory Motor Res. 11:1994;243-257.
    • (1994) Somatosensory Motor Res. , vol.11 , pp. 243-257
    • Thalhammer, J.G.1    Raymond, S.A.2    Popitz, B.3    Strichartz, G.R.4
  • 34
    • 0016167588 scopus 로고
    • Afferent C units responding to mechanical, thermal and chemical stimuli in human non-glabrous skin
    • Torebjörk H.E. Afferent C units responding to mechanical, thermal and chemical stimuli in human non-glabrous skin. Acta physiol. scand. 92:1974;374-390.
    • (1974) Acta Physiol. Scand. , vol.92 , pp. 374-390
    • Torebjörk, H.E.1
  • 35
    • 0014889228 scopus 로고
    • C-fiber units recorded from human sensory nerve fascicles in situ. A preliminary report
    • Torebjörk H.E., Hallin R.G. C-fiber units recorded from human sensory nerve fascicles in situ. A preliminary report. Acta Soc. Med. upsal. 75:1970;81-84.
    • (1970) Acta Soc. Med. Upsal. , vol.75 , pp. 81-84
    • Torebjörk, H.E.1    Hallin, R.G.2
  • 36
    • 0016252491 scopus 로고
    • Responses in human A and C fibers to repeated electrical intradermal stimulation
    • Torebjörk H.E., Hallin R.G. Responses in human A and C fibers to repeated electrical intradermal stimulation. J. Neurol. Neurosurg. Psychiat. 37:1974;653-664.
    • (1974) J. Neurol. Neurosurg. Psychiat. , vol.37 , pp. 653-664
    • Torebjörk, H.E.1    Hallin, R.G.2
  • 37
    • 0021368388 scopus 로고
    • Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: Simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibers
    • Torebjörk H.E., LaMotte R.H., Robinson C.J. Peripheral neural correlates of magnitude of cutaneous pain and hyperalgesia: simultaneous recordings in humans of sensory judgments of pain and evoked responses in nociceptors with C-fibers. J. Neurophysiol. 51:1984;325-339.
    • (1984) J. Neurophysiol. , vol.51 , pp. 325-339
    • Torebjörk, H.E.1    Lamotte, R.H.2    Robinson, C.J.3
  • 38
    • 0019478576 scopus 로고
    • C nociceptor activity in human nerve during painful and non painful skin stimulation
    • Van Hees J., Gybels J. C nociceptor activity in human nerve during painful and non painful skin stimulation. J. Neurol. Neurosurg. Psychiat. 44:1981;600-607.
    • (1981) J. Neurol. Neurosurg. Psychiat. , vol.44 , pp. 600-607
    • Van Hees, J.1    Gybels, J.2
  • 39
    • 0033571905 scopus 로고    scopus 로고
    • Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin
    • Weidner C., Schmelz M., Schmidt R., Hansson B., Handwerker H.O., Torebjörk H.E. Functional attributes discriminating mechano-insensitive and mechano-responsive C nociceptors in human skin. J. Neurosci. 19:1999;10184-10190.
    • (1999) J. Neurosci. , vol.19 , pp. 10184-10190
    • Weidner, C.1    Schmelz, M.2    Schmidt, R.3    Hansson, B.4    Handwerker, H.O.5    Torebjörk, H.E.6
  • 40
    • 0026059301 scopus 로고
    • Delayed activation of nociceptors: Correlation with delayed pain sensations induced by sustained stimuli
    • White D.M., Taiwo Y.O., Coderre T.J., Levine J.D. Delayed activation of nociceptors: correlation with delayed pain sensations induced by sustained stimuli. J. Neurophysiol. 66:1991;729-734.
    • (1991) J. Neurophysiol. , vol.66 , pp. 729-734
    • White, D.M.1    Taiwo, Y.O.2    Coderre, T.J.3    Levine, J.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.