-
1
-
-
0030700533
-
Estimating the electrostatic potential at the acetylcholine receptor agonist site using power saturation EPR
-
Addona, G. H., S H. Andrews, and D. S. Cafiso. 1997. Estimating the electrostatic potential at the acetylcholine receptor agonist site using power saturation EPR. Biochim. Biophys. Acta. 1329:74-84.
-
(1997)
Biochim. Biophys. Acta.
, vol.1329
, pp. 74-84
-
-
Addona, G.H.1
Andrews, S.H.2
Cafiso, D.S.3
-
2
-
-
0030032121
-
Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptors
-
Akk, G., and A. Auerbach. 1996. Inorganic, monovalent cations compete with agonists for the transmitter binding site of nicotinic acetylcholine receptors. Biophys. J. 70:2652-2658.
-
(1996)
Biophys. J.
, vol.70
, pp. 2652-2658
-
-
Akk, G.1
Auerbach, A.2
-
4
-
-
0024725677
-
Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor
-
Blount, P., and J. P. Merlie. 1989. Molecular basis of the two nonequivalent ligand binding sites of the muscle nicotinic acetylcholine receptor. Neuron. 3:349-357.
-
(1989)
Neuron
, vol.3
, pp. 349-357
-
-
Blount, P.1
Merlie, J.P.2
-
5
-
-
0019225784
-
3H]acetylcholine to Torpedo postsynaptic membranes: Association and dissociation rate constants by rapid mixing and ultrafiltration
-
3H]acetylcholine to Torpedo postsynaptic membranes: association and dissociation rate constants by rapid mixing and ultrafiltration. Biochemistry. 19: 5353-5358.
-
(1980)
Biochemistry
, vol.19
, pp. 5353-5358
-
-
Boyd, N.D.1
Cohen, J.B.2
-
8
-
-
0004021770
-
Interactions of local anesthetics with Torpedo nicotinic acetylcholine receptors
-
Plenum Publishing Corporation, New York
-
Cohen, J. B., L. A. Correll, E. B. Dreyer, I. R. Kuisk, D. C. Medynski, and N. P. Strnad. 1986. Interactions of local anesthetics with Torpedo nicotinic acetylcholine receptors. In Molecular and Cellular Mechanisms of Anesthetics. Plenum Publishing Corporation, New York. 111-124.
-
(1986)
Molecular and Cellular Mechanisms of Anesthetics
, pp. 111-124
-
-
Cohen, J.B.1
Correll, L.A.2
Dreyer, E.B.3
Kuisk, I.R.4
Medynski, D.C.5
Strnad, N.P.6
-
9
-
-
0028852622
-
Structure of the nicotinic receptor acetylcholine-binding site. Identification of acidic residues in the delta subunit within 0.9 nm of the alpha subunit-binding site disulfide
-
Czajkowski, C., and A. Karlin. 1995. Structure of the nicotinic receptor acetylcholine-binding site. Identification of acidic residues in the delta subunit within 0.9 nm of the alpha subunit-binding site disulfide. J. Biol. Chem. 270:3160-3164.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 3160-3164
-
-
Czajkowski, C.1
Karlin, A.2
-
10
-
-
0027522236
-
Functional architecture of the nicotinic acetylcholine receptor: A prototype of ligand-gated ion channels
-
Devillers-Thiery, A., J. L. Galzi, J. L. Eisele, S. Bertrand, and J.-P. Changeux. 1993. Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channels. J. Membr. Biol. 136:97-112.
-
(1993)
J. Membr. Biol.
, vol.136
, pp. 97-112
-
-
Devillers-Thiery, A.1
Galzi, J.L.2
Eisele, J.L.3
Bertrand, S.4
Changeux, J.-P.5
-
11
-
-
0030043489
-
Cation-pi interactions in chemistry and biology: A new view of benzene, Phe, Tyr, and Trp
-
Dougherty, D. A. 1996. Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp. Science. 271:163-168.
-
(1996)
Science
, vol.271
, pp. 163-168
-
-
Dougherty, D.A.1
-
12
-
-
0024460245
-
A possible model for the inner wall of the acetylcholine receptor channel
-
Furois-Corbin, S., and A. Pullman. 1989. A possible model for the inner wall of the acetylcholine receptor channel. Biochim. Biophys. Acta. 984:339-350.
-
(1989)
Biochim. Biophys. Acta.
, vol.984
, pp. 339-350
-
-
Furois-Corbin, S.1
Pullman, A.2
-
13
-
-
0021041862
-
Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata
-
Heidmann, T., J. Bernhardt, E. Neumann, and J. P. Changeux. 1983. Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata. Biochemistry. 22:5452-5459.
-
(1983)
Biochemistry
, vol.22
, pp. 5452-5459
-
-
Heidmann, T.1
Bernhardt, J.2
Neumann, E.3
Changeux, J.P.4
-
14
-
-
0023268737
-
Interaction of noncompetitive inhibitors with the acetylcholine receptor. The site specificity and spectroscopic properties of ethidium binding
-
Herz, J. M., D. A. Johnson, and P. Taylor. 1987. Interaction of noncompetitive inhibitors with the acetylcholine receptor. The site specificity and spectroscopic properties of ethidium binding. J. Biol. Chem. 262:7238-7247.
-
(1987)
J. Biol. Chem.
, vol.262
, pp. 7238-7247
-
-
Herz, J.M.1
Johnson, D.A.2
Taylor, P.3
-
15
-
-
0030011258
-
The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor
-
Hucho, F., V. I. Tsetlin, and J. Machold. 1996. The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor. Eur. J. Biochem. 239:539-557.
-
(1996)
Eur. J. Biochem.
, vol.239
, pp. 539-557
-
-
Hucho, F.1
Tsetlin, V.I.2
Machold, J.3
-
16
-
-
0023748825
-
Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance
-
Imoto, K., C. Busch, B. Sakmann, M. Mishina, T. Konno, J. Nakai, H. Bujo, Y. Mori, K. Fukuda, and S. Numa. 1988. Rings of negatively charged amino acids determine the acetylcholine receptor channel conductance. Nature. 335:645-648.
-
(1988)
Nature
, vol.335
, pp. 645-648
-
-
Imoto, K.1
Busch, C.2
Sakmann, B.3
Mishina, M.4
Konno, T.5
Nakai, J.6
Bujo, H.7
Mori, Y.8
Fukuda, K.9
Numa, S.10
-
17
-
-
84965075853
-
A study of the desensitization produced by acetylcholine at the motor endplate
-
Katz, B., and S. Thesleff. 1957. A study of the desensitization produced by acetylcholine at the motor endplate. J. Physiol. 138:63-80.
-
(1957)
J. Physiol.
, vol.138
, pp. 63-80
-
-
Katz, B.1
Thesleff, S.2
-
18
-
-
0018351106
-
Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue
-
Krodel, E. K., R. A. Beckman, and J. B. Cohen. 1979. Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue. Mol. Pharmacol. 15:294-312.
-
(1979)
Mol. Pharmacol.
, vol.15
, pp. 294-312
-
-
Krodel, E.K.1
Beckman, R.A.2
Cohen, J.B.3
-
19
-
-
0004270702
-
-
McGraw-Hill Book Company, New York
-
Levine, I. 1988. Physical Chemistry. McGraw-Hill Book Company, New York.
-
(1988)
Physical Chemistry
-
-
Levine, I.1
-
20
-
-
0031059313
-
Quinacrine and ethidium bromide bind the same locus on the nicotinic acetylcholine receptor from Torpedo californica
-
Lurtz, M. M., M. L. Hareland, and S. E. Pedersen. 1997. Quinacrine and ethidium bromide bind the same locus on the nicotinic acetylcholine receptor from Torpedo californica. Biochemistry. 36:2068-2075.
-
(1997)
Biochemistry
, vol.36
, pp. 2068-2075
-
-
Lurtz, M.M.1
Hareland, M.L.2
Pedersen, S.E.3
-
21
-
-
0029929234
-
The contributions of aspartyl residues in the acetylcholine receptor gamma and delta subunits to the binding of agonists and competitive antagonists
-
Martin, M., C. Czajkowski, and A. Karlin. 1996. The contributions of aspartyl residues in the acetylcholine receptor gamma and delta subunits to the binding of agonists and competitive antagonists. J. Biol. Chem. 271:13497-13503.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 13497-13503
-
-
Martin, M.1
Czajkowski, C.2
Karlin, A.3
-
22
-
-
0017905087
-
Local anaesthetics transiently block currents through single acetylcholine-receptor channels
-
Neher, E., and J. H. Steinbach. 1978. Local anaesthetics transiently block currents through single acetylcholine-receptor channels. J. Physiol. 277: 153-176.
-
(1978)
J. Physiol.
, vol.277
, pp. 153-176
-
-
Neher, E.1
Steinbach, J.H.2
-
23
-
-
0018651261
-
3H]acetylcholine by Torpedo postsynaptic membranes: Stoichiometry and ligand interactions
-
3H]acetylcholine by Torpedo postsynaptic membranes: stoichiometry and ligand interactions. Biochemistry. 18:5464-5475.
-
(1979)
Biochemistry
, vol.18
, pp. 5464-5475
-
-
Neubig, R.R.1
Cohen, J.B.2
-
24
-
-
0019317512
-
Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands
-
Nolle, H. J., T. L. Rosenberry, and E. Neumann. 1980. Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands. Biochemistry. 19:3705-3711.
-
(1980)
Biochemistry
, vol.19
, pp. 3705-3711
-
-
Nolle, H.J.1
Rosenberry, T.L.2
Neumann, E.3
-
25
-
-
0024319944
-
Desensitization of the nicotinic acetylcholine receptor: Molecular mechanisms and effect of modulators
-
Ochoa, E. L., A. Chattopadhyay, and M. G. McNamee. 1989. Desensitization of the nicotinic acetylcholine receptor: molecular mechanisms and effect of modulators. Cell Mol. Neurobiol 9:141-178.
-
(1989)
Cell Mol. Neurobiol
, vol.9
, pp. 141-178
-
-
Ochoa, E.L.1
Chattopadhyay, A.2
McNamee, M.G.3
-
26
-
-
0028819573
-
Site-selective photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor by azide derivatives of ethidium bromide
-
Pedersen, S. E. 1995. Site-selective photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor by azide derivatives of ethidium bromide. Mol. Pharmacol. 47:1-9.
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 1-9
-
-
Pedersen, S.E.1
-
27
-
-
0025308169
-
d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor
-
Pedersen, S. E., and J. B. Cohen. 1990. d-Tubocurarine binding sites are located at alpha-gamma and alpha-delta subunit interfaces of the nicotinic acetylcholine receptor. Proc. Natl. Acad. Sci. USA. 87:2785-2789.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 2785-2789
-
-
Pedersen, S.E.1
Cohen, J.B.2
-
28
-
-
0022972430
-
Location of ligand-binding sites on the nicotinic acetylcholine receptor alpha-subunit
-
Pedersen, S. E., E. B. Dreyer, and J. B. Cohen. 1986. Location of ligand-binding sites on the nicotinic acetylcholine receptor alpha-subunit. J. Biol. Chem. 261:13735-13743.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 13735-13743
-
-
Pedersen, S.E.1
Dreyer, E.B.2
Cohen, J.B.3
-
29
-
-
0029588321
-
Interaction of d-tubocurarine analogs with the Torpedo nicotinic acetylcholine receptor. Methylation and stereoisomerization affect site-selective competitive binding and binding to the noncompetitive site
-
Pedersen, S. E., and R. V. Papineni. 1995. Interaction of d-tubocurarine analogs with the Torpedo nicotinic acetylcholine receptor. Methylation and stereoisomerization affect site-selective competitive binding and binding to the noncompetitive site. J. Biol. Chem. 270:31141-31150.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 31141-31150
-
-
Pedersen, S.E.1
Papineni, R.V.2
-
30
-
-
0029958548
-
Molecular dissection of subunit interfaces in the acetylcholine receptor. Identification of residues that determine agonist selectivity
-
Prince, R. J., and S. M. Sine. 1996. Molecular dissection of subunit interfaces in the acetylcholine receptor. Identification of residues that determine agonist selectivity. J. Biol. Chem. 271:25770-25777.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 25770-25777
-
-
Prince, R.J.1
Sine, S.M.2
-
31
-
-
33845282579
-
Acetylcholinesterase: Enzyme structure, reaction dynamics, and virtual transition states
-
Quinn, D. M. 1987. Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states. Chem. Rev. 87:955-979.
-
(1987)
Chem. Rev.
, vol.87
, pp. 955-979
-
-
Quinn, D.M.1
-
32
-
-
0032548470
-
Transient low-affinity agonist binding to Torpedo postsynaptic membranes resolved by using sequential mixing stopped-flow fluorescence spectroscopy
-
Raines, D. E., and N. S. Krishnan. 1998. Transient low-affinity agonist binding to Torpedo postsynaptic membranes resolved by using sequential mixing stopped-flow fluorescence spectroscopy. Biochemistry. 37: 956-964.
-
(1998)
Biochemistry
, vol.37
, pp. 956-964
-
-
Raines, D.E.1
Krishnan, N.S.2
-
33
-
-
0016115777
-
The cation sensitivity of the acetylcholine receptor from Torpedo californica
-
Schmidt, J., and M. A. Raftery. 1974. The cation sensitivity of the acetylcholine receptor from Torpedo californica. J. Neurochem. 23:617-623.
-
(1974)
J. Neurochem.
, vol.23
, pp. 617-623
-
-
Schmidt, J.1
Raftery, M.A.2
-
34
-
-
0025123090
-
Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities
-
Sine, S. M., T. Claudio, and F. J. Sigworth. 1990. Activation of Torpedo acetylcholine receptors expressed in mouse fibroblasts. Single channel current kinetics reveal distinct agonist binding affinities. J. Gen. Phys. 96:395-437.
-
(1990)
J. Gen. Phys.
, vol.96
, pp. 395-437
-
-
Sine, S.M.1
Claudio, T.2
Sigworth, F.J.3
-
35
-
-
0029085766
-
Molecular dissection of subunit interfaces in the acetylcholine receptor: Identification of determinants of alpha-conotoxin M1 selectivity
-
Sine, S. M., H. J. Kreienkamp, N. Bren, R. Maeda, and P. Taylor. 1995. Molecular dissection of subunit interfaces in the acetylcholine receptor: identification of determinants of alpha-conotoxin M1 selectivity. Neuron. 15:205-211.
-
(1995)
Neuron
, vol.15
, pp. 205-211
-
-
Sine, S.M.1
Kreienkamp, H.J.2
Bren, N.3
Maeda, R.4
Taylor, P.5
-
36
-
-
0017708049
-
Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent extracted forms from Torpedo marmorata electric organ
-
Sobel, A., M. Weber, and J.-P. Changeux. 1977. Large-scale purification of the acetylcholine-receptor protein in its membrane-bound and detergent extracted forms from Torpedo marmorata electric organ. Eur. J. Biochem. 80:215-224.
-
(1977)
Eur. J. Biochem.
, vol.80
, pp. 215-224
-
-
Sobel, A.1
Weber, M.2
Changeux, J.-P.3
-
37
-
-
0028355745
-
Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates
-
Stauffer, D. A., and A. Karlin. 1994. Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates. Biochemistry. 33:6840-6849.
-
(1994)
Biochemistry
, vol.33
, pp. 6840-6849
-
-
Stauffer, D.A.1
Karlin, A.2
-
38
-
-
0029970913
-
Anionic residue in the alpha-subunit of the nicotinic acetylcholine receptor contributing to subunit assembly and ligand binding
-
Sugiyama, N., A. E. Boyd, and P. Taylor. 1996. Anionic residue in the alpha-subunit of the nicotinic acetylcholine receptor contributing to subunit assembly and ligand binding. J. Biol. Chem. 271:26575-26581.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 26575-26581
-
-
Sugiyama, N.1
Boyd, A.E.2
Taylor, P.3
-
39
-
-
0025778840
-
Atomic structure of acetylcholinesterase from Torpedo californica: A prototypic acetylcholine-binding protein
-
Sussman, J. L., M. Harel, F. Frolow, C. Oefner, A. Goldman, L. Toker, and I. Silman. 1991. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science. 253: 872-879.
-
(1991)
Science
, vol.253
, pp. 872-879
-
-
Sussman, J.L.1
Harel, M.2
Frolow, F.3
Oefner, C.4
Goldman, A.5
Toker, L.6
Silman, I.7
-
40
-
-
0027386759
-
Acetylcholinesterase: Electrostatic steering increases the rate of ligand binding
-
Tan, R. C., T. N. Truong, J. A. McCammon, and J. L. Sussman. 1993. Acetylcholinesterase: electrostatic steering increases the rate of ligand binding. Biochemistry. 32:401-403.
-
(1993)
Biochemistry
, vol.32
, pp. 401-403
-
-
Tan, R.C.1
Truong, T.N.2
McCammon, J.A.3
Sussman, J.L.4
-
41
-
-
0017082837
-
Synthesis of fluorescent acyl-cholines with agonistic properties: Pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor-rich membrane fragments
-
Waksman, G., M. C. Fournie-Zaluski, and B. Roques. 1976. Synthesis of fluorescent acyl-cholines with agonistic properties: pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor-rich membrane fragments. FEBS Lett. 67:335-342.
-
(1976)
FEBS Lett.
, vol.67
, pp. 335-342
-
-
Waksman, G.1
Fournie-Zaluski, M.C.2
Roques, B.3
-
42
-
-
0020362247
-
Activation and inactivation kinetics of Torpedo californica acetylcholine receptor in reconstituted membranes
-
Walker, J. W., K. Takeyasu, and M. G. McNamee. 1982. Activation and inactivation kinetics of Torpedo californica acetylcholine receptor in reconstituted membranes. Biochemistry. 21:5384-5389.
-
(1982)
Biochemistry
, vol.21
, pp. 5384-5389
-
-
Walker, J.W.1
Takeyasu, K.2
McNamee, M.G.3
-
43
-
-
0026625673
-
Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist
-
White, B. H., and J. B. Cohen. 1992. Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist. J. Biol. Chem. 267:15770-15783.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15770-15783
-
-
White, B.H.1
Cohen, J.B.2
-
44
-
-
0032514762
-
From ab initio quantum mechanics to molecular neurobiology: A cation-pi binding site in the nicotinic receptor
-
Zhong, W., J. P. Gallivan, Y. Zhang, L. Li, H. A. Lester, and D. A. Dougherty. 1998. From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor. Proc. Natl. Acad. Sci. USA. 95:12088-12093.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12088-12093
-
-
Zhong, W.1
Gallivan, J.P.2
Zhang, Y.3
Li, L.4
Lester, H.A.5
Dougherty, D.A.6
|