Hypothermia differentially increases extracellular signal-regulated kinase and stress-activated protein kinase/c-Jun terminal kinase activation in the hippocampus during reperfusion after asphyxial cardiac arrest

Neuroscience

Volumn 98, Issue 4, 2000, Pages 677-685

  Hicks, S D ^a,b   Parmele, K T ^a   Defranco, D B ^b   Klann, E ^b   Callaway, C W ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Heart arrest; Hippocampus; Hypothermia; MAPK; Phosphorylation; Transient cerebral ischemia

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPHYXIA; CONTROLLED STUDY; ENZYME ACTIVATION; HEART ARREST; HIPPOCAMPUS; HYPOTHERMIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION; SIGNAL TRANSDUCTION; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; ASPHYXIA; ENZYME INDUCTION; HEART ARREST; HIPPOCAMPUS; HYPOTHERMIA; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-JUN; RATS; REPERFUSION;

EID: 0034048006     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00169-X     Document Type: Article

References (53)

1. Ahn N.G., Seger R., Krebs E.G. The mitogen-activated protein kinase activator. Curr. Opin. Cell Biol. 4:1992;962-999.
2. Alessi D.R., Gomez N., Moorhead G., Lewis T., Keyse S.M., Cohen P. Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100 in various cell lines. Curr. Biol. 5:1995;283-295.
3. Atkins C., Selcher J., Petraits J., Trzasko J., Sweatt J. The MAPK cascade is required for mammalian associative learning. Nature Neurosci. 1:1998;602-609.
4. Boulton Y., Nye S., Robbins D., Ip N., Redziejewska E., Morgenbesser S., DePinho R., Panayotatos N., Cobb M., Yancopoulos G. ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and nGF. Cell. 65:1991;663-675.
5. Cobb M., Goldsmith E.J. How MAP kinases are regulated. J. biol. Chem. 270:1995;14843-14846.
6. Coimbra C., Wieloch T. Moderate hypothermia mitigates neuronal damage in the rat brain when initiated several hours following transient cerebral ischemia. Acta neuropath. 87:1994;325-331.
7. Colbourne F., Corbett D. Delayed and prolonged post-ischemic hypothermia is neuroprotective in the gerbil. Brain Res. 654:1994;265-272.
8. Colbourne F., Corbett D. Delayed postischemic hypothermia: a six-month survival study using behavioral and histological assessments of neuroprotection. J. Neurosci. 15:1995;7250-7260.
9. Colbourne F., Sutherland G.R., Auer R.N. An automated system for regulating brain temperature in awake and freely moving rodents. J. Neurosci. Meth. 67:1996;185-190.
10. Colbourne F., Li H., Buchan A. Indefatigable CA1 sector neuroprotection with mild hypothermia induced 6 hours after severe forebrain ischemia in rats. J. cerebr. Blood Flow Metab. 19:1999;742-749.
11. Davis R. The mitogen-activated protein kinase signal transduction pathway. J. biol. Chem. 208:1993;14553-14556.
12. Derijard B., Raingeaud J., Barret T., Wu I.H., Han J., Ulevitch R.J., Davis R.J. Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science. 267:1995;682-685.
13. Eisenberg M., Bergner L., Hallstrom A. Epidemiology of cardiac arrest and resuscitation in children. Ann. emerg. Med. 12:1983;672-674.
14. English J., Sweatt J. Activation of the p42 mitogen-activated protein kinase in hippocampal long-term potentiation. J. biol. Chem. 271:1996;24,329-24,332.
15. Herdegen T., Claret F., Tuula K., Martin-Villalba A., Winter C., Hunter T., Karin M. Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J. Neurosci. 18:1998;5124-5135.
16. Hicks S., DeFranco D., Callaway C. Hypothermia during reperfusion after asphyxial cardiac arrest improves functional recovery and selectively alters stress-induced protein expression. J. cerebr. Blood Flow Metab. 20:2000;520-530.
17. Hill C., Treisman R. Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell. 80:1995;199-211.
18. Hu B.R., Wieloch T. Tyrosine phosphorylation and activation of mitogen-activated protein kinase in the rat brain following transient cerebral ischemia. J. Neurochem. 62:1994;1357-1367.
19. Johnson N., Gardner A., Diener K., Lange-Carter C., Gleavy J., Jarpe M., Minden A., Karin M., Zon L., Johnson G. Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase induce cell death. J. biol. Chem. 271:1996;3229-3237.
20. Katz L., Callaway C.W., Kagan V.E., Kochanek P.M. Electron spin resonance measure of brain antioxidant activity during ischemia/reperfusion. NeuroReport. 9:1998;1587-1593.
21. Katz L., Ebmeyer U., Safar P., Radovsky A., Neumar R. Outcome model of asphyxial cardiac arrest in rats. J. cerebr. Blood Flow Metab. 15:1995;1032-1039.
22. Kawai K., Nitecka L., Ruetzler C., Nagashima G., Jou F., Mies G., Nowak T., Saito N., Lohr J., Klatzo I. Global cerebral ischemia associated with cardiac arrest in the rat: 1. Dynamics of early neuronal changes. J. cerebr. Blood. Flow. Metab. 12:1992;238-249.
23. Khokhlatchev A., Canagarajah B., Wilsbacher J., Robinson M., Atkinson M., Goldsmith E., Cobb M.H. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell. 93:1998;605-615.
24. Kummer J., Rao P., Heindenreich K. Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase. J. biol. Chem. 272:1997;20,490-20,494.
25. Kyriakis J., Banerjee P., Nikolakaki E., Da T., Ruble E., Ahmad M., Avruch J., Woodgett J. The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 369:1994;156-161.
26. Kyriakis J.M., App H., Zhang X.-F., Banerjee P., Brautigan D., Rapp U.R., Avruch J. Raf-1 activates MAP kinase-kinase. Nature. 358:1992;417-421.
27. Le-Niculescu H., Bonfoco E., Kasuya Y., Claret F.X., Green D.R., Karin M. Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to FAS ligand induction and cell death. Molec. cell. Biol. 19:1999;751-763.
28. Lin A., Minden A., Martinetto H., Claret R.-X., Lange-Carter C., Mercurio F., Johnson G.L., Karin M. Identification of a dual specificity kinase that activates the Jun kinase and p38-Mpk2. Science. 268:1995;286-290.
29. Meriin A., Yaglom J.A., Gabal V.L., Mosser D.D., Zon L., Sherman M.Y. Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72. Molec. cell. Biol. 19:1999;2547-2555.
30. Morrison D., Cutler R.E. The complexity of Raf-1 regulation. Curr. Opin. Cell Biol. 9:1997;174-179.
31. Olah Z., Komoly S., Nagashima N., Joo F., Rapp U.R., Anderson W.B. Cerebral ischemia induces transient intracellular redistribution and intranuclear translocation of the raf proto-oncogene product in hippocampal pyramid cells. Expl Brain Res. 84:1991;403-410.
32. O'Rourke P.P. Outcome of children who are apneic and pulseless in the emergency room. Crit. Care Med. 14:1986;466-468.
33. Ozawa H., Shioda S., Dohi K., Matsumoto H., Mizushima H., Zhou S.J., Funahashi H., Nakai Y., Nakajo S., Matsumoto K. Delayed neuronal cell death in the rat hippocampus is mediated by the mitogen-activated protein kinase signal transduction pathway. Neurosci. Lett. 262:1999;57-60.
34. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 1997;Academic, San Diego, CA.
35. Pulsinelli W., Brierly J.B., Plum F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann. Neurol. 11:1982;491-498.
36. Roberson E.D., English D., Adams J.P., Selcher J., Kondratick C., Sweatt J. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. J. Neurosci. 19:1999;4337-4348.
37. Robinson M., Cobb M. Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 9:1997;180-186.
38. Ross D., Graham D.I. Selective loss and selective sparing of neurons in the thalamic reticular nucleus following human cardiac arrest. J. cerebr. Blood Flow Metab. 13:1993;558-567.
39. Schaeffer H., Catling A., Eblen S., Collier L., Krauss A., Weber M. MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade. Science. 281:1998;1668-1674.
40. Schulz S., Siemer H., Krug M., Hollt V. Direct evidence for biphasic cAMP responsive element-binding protein phosphorylation during long-term potentiation in the rat dentate gyrus in vivo. J. Neurosci. 19:1999;5683-5692.
41. Shamloo M., Rytter R., Weiloch T. Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning. Neuroscience. 93:1999;81-88.
42. Singer C., Figueroa-Masot X., Batchelor R., Dorsa D. The mitogen-activated protein kinase pathway mediates estrogen neuroprotection after glutamate toxicity in primary cortical neurons. J. Neurosci. 19:1999;2455-2463.
43. Sluss K., Barrett T., Derljard B., Davis R.J. Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Molec. cell. Biol. 14:1994;8376-8384.
44. Takekawa M., Maeda T., Saito H. Protein phosphatase 2Ca inhibits the human stress-responsive p38 and JNK MAPK pathways. Eur. molec. Biol. Org. J. 17:1998;4744-4752.
45. Thomas K., Hunt S. The regional distribution of extracellular regulated kinase-1 and -2 messenger RNA in the adult rat central nervous system. Neuroscience. 56:1993;741-757.
46. Thomas K.L., Laroche S., Errington M.L., Bliss T., Hunt S. Spatial and temporal changes in signal transduction pathways during LTP. Neuron. 13:1994;737-745.
47. 2-terminal kinase. Proc. natn. Acad. Sci. U.S.A. 94:1997;7337-7342.
48. Walton K., DiRicco R., Bartlett B., Koury E., Marcy V., Jarvis B., Schaefer E., Bhat R. Activation of p38 MAPK in microglia after ischemia. J. Neurochem. 70:1998;1764-1767.
49. Watson A., Eilers A., Lallemand D., Kyriakis J., Rubin L., Ham J. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J. Neurosci. 18:1998;751-762.
50. Whitmarsh A., Cavanagh J., Tournier C., Yasuda J., Davis R. A mammalian scaffold complex that selectively mediates MAP kinase activation. Science. 281:1998;1671-1674.
51. Xia Z., Dickens M.R.J., Davis R., Greenberg M. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1995;1326-1331.
52. Yaglom J., Gabai V.L., Meriin A.B., Mosser D.D., Sherman M.Y. The function of HSP72 in suppression of c-Jun N-terminal kinase activation can be dissociated from its role in prevention of protein damage. J. biol. Chem. 274:1999;20223-20228.
53. Yanamoto H., Hong S.C., Soleau S., Kasell N.F., Lee K.S. Mild postischemic hypothermia limits cerebral injury following transient focal ischemia in rat neocortex. Brain Res. 718:1996;207-211.