WP14865A and B, new cathepsins B and L inhibitors produced by Aphanoascus fulvescens. I. taxonomy, production, purification and biological properties

Journal of Antibiotics

Volumn 53, Issue 5, 2000, Pages 449-458

  Otsuka, Takanao ^a   Muramatsu, Yuko ^a   Nakanishi, Tomoko ^a   Hatanaka, Hiroshi ^a   Okamoto, Masanori ^a   Hino, Motohiro ^a   Hashimoto, Seiji ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN B; CATHEPSIN L; ENZYME INHIBITOR; UNCLASSIFIED DRUG; WF 14865A; WF 14865B; CATHEPSIN; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DRUG DERIVATIVE; EPOXIDE; ISOLEUCINE; PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG MANUFACTURE; DRUG POTENCY; DRUG PURIFICATION; DRUG STRUCTURE; FEMALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPECTROSCOPY; TAXONOMY; ANIMAL; ASCOMYCETES; CHEMISTRY; CLASSIFICATION; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; INSTITUTE FOR CANCER RESEARCH MOUSE; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; LIVER; METABOLISM;

APHANOASCUS FULVESCENS;

ANIMALS; ASCOMYCOTA; CATHEPSIN B; CATHEPSINS; CHROMATOGRAPHY, LIQUID; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENDOPEPTIDASES; EPOXY COMPOUNDS; FEMALE; HUMANS; ISOLEUCINE; LIVER; MICE; MICE, INBRED ICR;

EID: 0034043560     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.449     Document Type: Article

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