Induction of chromosomal aberrations and growth-transformation of lymphoblastoid cell lines by inhibition of reactive oxygen species-induced interleukin-6

Laboratory Investigation

Volumn 80, Issue 5, 2000, Pages 725-734

  Miwa, Hideaki ^a   Kanno, Hiroyuki ^a,c   Munakata, Satoru ^a   Akano, Yumiko ^b   Taniwaki, Masafumi ^b   Aozasa, Katsuyuki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; XANTHINE OXIDASE;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL DEATH; CELL GROWTH; CELL KINETICS; CELL SURVIVAL; CHROMOSOME ABERRATION; CHROMOSOME STRUCTURE; COLONY FORMATION; CONTROLLED STUDY; CYTOGENETICS; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL;

EID: 0034040365     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780076     Document Type: Article

References (51)

1. Akira S, Taga T, and Kishimoto T (1993). Interleukin-6 in biology and medicine. Adv Immunol 54:1-78.
2. Ando T, Kusugami K, Ohsuga M, Ina K, Shinoda M, Konagaya T, Sakai T, Imada A, Kasuga N, Nada T, Ichiyama S, and Blaser MJ (1998). Differential normalization of mucosal interleukin-8 and interleukin-6 activity after Helicobacter pylori eradication. Infect Immun 66:4742-4747.
3. Aozasa K (1992). Malignant lymphoma of the mucosaassociated lymphoid tissue. Am J Surg Pathol 16:90-92.
4. Banchereau J, De Paoli P, Vallé A, Garcia E, and Rousset F (1991). Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 251:70-72.
5. Bertoni F, Cazzaniga G, Bosshard G, Roggero E, Barbazza R, De Boni M, Capella C, Pedrinis E, Cavalli F, Blondi A, and Zucca E (1997). Immunoglobulin heavy chain diversity genes rearrangement pattern indicates that MALT-type gastric lymphoma B cells have undergone an antigen selection process. Br J Haematol 97:830-836.
6. Bursch W, Lauer B, Timmermann-Trosiener I, Barthel G, Schuppler J, and Schulte-Hermann R (1984). Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters. Carcinogenesis 5:453-458.
7. Buschle M, Campana D, Carding SR, Richard C, Hoffbrand AV, and Brenner MK (1993). Interferon γ inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med 177:213-218.
8. Carson DA, Seto S, Wasson DB, and Carrera CJ (1986). DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res 164:273-281.
9. Cerutti PA and Trump BF (1991). Inflammation and oxidative stress in carcinogenesis. Cancer Cells 3:1-7.
10. Cigudosa JC, Parsa NZ, Louie DC, Filippa DA, Jhanwar SC, Johansson B, Mitelman F, and Chaganti RSK (1999). Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas. Genes Chromosomes Cancer 25: 123-133.
11. Duell H, Lengfelder E, Fink R, Giesen R, and Bauchinger M (1995). Effect of activated oxygen species in human lymphocytes. Mutat Res 336:29-38.
12. L rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli. J Immunol 155:66-75.
13. Gaidano G and Dalla-Favera R (1993). Biologic and molecular characterization of non-Hodgkin's lymphoma. Curr Opin Oncol 5:776-784.
14. Glaser R, Theil KS, Bonneau RH, Sheridan JF, Vasquez M, and Allen CM (1993). Spontaneous development of a chromosomal translocation 5;14 in an Epstein-Barr-virus-associated B-cell lymphoma in a SCID mouse. Int J Cancer 55:281-287.
15. Gong J, Traganos F, and Darzynkiewicz Z (1994). A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal Biochem 218:314-319.
16. Greiner A, Knörr C, Qin Y, Sebald W, Schimpl A, Banchereau J, and Müller-Hermelink HK (1997). Low-grade B cell lymphomas of mucosa-associated lymphoid tissue (MALT-type) require CD40-mediated signaling and Th2-type cytokines for in vitro growth and differentiation. Am J Pathol 150:1583-1593.
17. H genes of high-grade mucosa-associated lymphoid tissue lymphomas show a high load of somatic mutations and evidence of antigen-dependent affinity maturation. Lab Invest 78:277-287.
18. Henderson S, Rowe M, Gregory C, Croom-Carter D, Wang F, Longnecker R, Kieff E, and Rickinson A (1991). Induction of bcl-2 expression by Epstein-Barr virus latent membrane protein 1 protects infected B cells from programmed cell death. Cell 65:1107-1115.
19. Hildebrandt AG and Roots I (1975). Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes. Arch Biochem Biophys 171:385-397.
20. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, and Korsmeyer SJ (1993). Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251.
21. International System for Human Cytogenetic Nomenclature (ISCN) 1995 (1995). Report of the standing committee on human cytogenetic nomenclature. Mitelman F, editor. Basel: S. Karger.
22. Iuchi K, Aozasa K, Yamamoto S, Mori T, Tajima K, Minato K, Mukai K, Komatsu H, Tagaki T, Kobashi Y, Yamabe H, and Shimoyama M (1989). Non-Hodgkin's lymphoma of the pleural cavity developing from long-standing pyothorax: Summary of clinical and pathological findings in thirty-seven cases. Jpn J Clin Oncol 19:249-257.
23. Iuchi K, Ichimiya A, Akashi A, Mizuta T, Lee YE, Tada H, Mori T, Sawamura K, Lee YS, Furuse K, Yamamoto S, and Aozasa K (1987). Non-Hodgkin's lymphoma of the pleural cavity developing from long-standing pyothorax. Cancer 60:1771-1775.
24. Kanno H, Wolfinbarger JB, and Bloom ME (1993). Aleutian mink disease parvovirus infection of mink peritoneal macrophages and human macrophage cell lines. J Virol 67:2075-2082.
25. Kanno H, Yasunaga Y, Ohsawa M, Taniwaki M, Iuchi K, Naka N, Torikai K, Shimoyama M, and Aozasa K (1996). Expression of Epstein-Barr virus latent infection genes and oncogenes in lymphoma cell lines derived from pyothorax-associated lymphoma. Int J Cancer 67:86-94.
26. Kato I, Tajima K, Suchi T, Aozasa K, Matsuzuka F, Kuma K, and Tominaga S (1985). Chronic thyroiditis as a risk factor of B-cell lymphoma in the thyroid gland. Jpn J Cancer Res 76:1085-1090.
27. Kellogg III EW and Fridovich I (1975). Superoxide, hydrogen peroxide, and singlet oxygen in lipid peroxidation by a xanthine oxidase system. J Biol Chem 250:8812-8817.
28. Muehlematter D, Larsson R, and Cerutti P (1988). Active oxygen induced DNA strand breakage and poly ADP-ribosylation in promotable and non-promotable JB6 mouse epidermal cells. Carcinogenesis 9:239-245.
29. Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, Orentreich N, Vogelman JH, and Friedman GD (1994). Helicobacter pylori infection and gastric lymphoma. N Engl J Med 330:1267-1271.
30. Phillips BJ, James TEB, and Anderson D (1984). Genetic damage in CHO cells exposed to enzymically generated active oxygen species. Mutat Res 126:265-271.
31. 2 release from human granulocytes during phagocytosis: I. Documentation, quantitation, and some regulating factors. J Clin Invest 55:945-955.
32. Rousset F, Garcia E, Defrance T, Péronne C, Vezzio N, Hsu DH, Kastelein R, Moore KW, and Banchereau J (1992). lnterleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 89:1890-1893.
33. Rowe M, Young LS, Crocker J, Stokes H, Henderson S, and Rickinson AB (1991). Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: Implications for the pathogenesis of EBV-positive lymphomas in man. J Exp Med 173:147-158.
34. Scala G, Quinto I, Ruocco MR, Arcucci A, Mallardo M, Caretto P, Forni G, and Venuta S (1990). Expression of an exogenous interleukin 6 gene in human Epstein Barr virus B cells confers growth advantage and in vivo tumorigenicity. J Exp Med 172:61-68.
35. Schraufstätter I, Hyslop PA, Jackson JH, and Cochrane CG (1988). Oxidant-induced DNA damage of target cells. J Clin Invest 82:1040-1050.
36. L. Cancer Res 55:2262-2265.
37. Scudiero DA, Shoemaker RH, Paull KD, Monks A, Tierney S, Nofziger TH, Currens MJ, Seniff D, and Boyd MR (1988). Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 48:4827-4833.
38. Sellins KS and Cohen JJ (1987). Gene induction by γ-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 139:3199-3206.
39. Shibanuma M, Kuroki T, and Nose K (1988). Induction of DNA replication and expression of proto-oncogene c-myc and c-fos in quiescent Balb/3T3 cells by xanthine/xanthine oxidase. Oncogene 3:17-21.
40. Sofuni T and Ishidate Jr M (1984). Induction of chromosomal aberrations in cultured Chinese hamster cells in a superoxide-generating system. Mutat Res 140:27-31.
41. Suematsu S, Matsuda T, Aozasa K, Akira S, Nakano N, Ohno S, Miyazaki J, Yamamura K, Hirano T, and Kishimoto T (1989). IgG1 plasmacytosis in interleukin-6 transgenic mice. Proc Natl Acad Sci USA 86:7547-7551.
42. Suematsu S, Matsusaka T, Matsuda T, Ohno S, Miyazaki J, Yamamura K, Hirano T, and Kishimoto T (1992). Generation of plasmacytomas with the chromosomal translocation t(12; 15) in interleukin 6 transgenic mice. Proc Natl Acad Sci USA 89:232-235.
43. Teague TK, Marrack P, Kappler JW, and Vella AT (1997). IL-6 rescues resting mouse T cells from apoptosis. J Immunol 158:5791-5796.
44. Tosato G, Tanner J, Jones KD, Revel M, and Pike SE (1990). Identification of interleukin-6 as an autocrine growth factor for Epstein-Barr virus-immortalized B cells. J Virol 64:3033-3041.
45. Tsujimoto Y and Croce CM (1986). Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci USA 83:5214-5218.
46. Weitberg AB, Weitzman SA, Destrempes M, Latt SA, and Stossel TP (1983). Stimulated human phagocytes produce cytogenetic changes in cultured mammalian cells. N Engl J Med 308:26-30.
47. Weitzman SA, Weitberg AB, Clark EP, and Stossel TP (1985). Phagocytes as carcinogens: Malignant transformation produced by human neutrophils. Science 227:1231-1233.
48. Whitacre CM and Cathcart MK (1992). Oxygen free radical generation and regulation of proliferative activity of human mononuclear cells responding to different mitogens. Cell Immunol 144:287-295.
49. Yokoyama A, Maruyama M, Ito M, Kohno N, Hiwada N, and Yano S (1992). Interleukin 6 activity in pleural effusion: Its diagnostic value and thrombopoietic activity. Chest 102: 1055-1059.
50. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, and Oren M (1991). Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 352:345-347.
51. 1/2/ C18 fibroblasts. Proc Natl Acad Sci USA 81:2085-2087.