Gas chromatography/negative ion chemical ionization mass spectrometry and liquid chromatography/electrospray ionization tandem mass spectrometry quantitative profiling of N-acetylcysteine conjugates of valproic acid in urine: Application in drug metabolism studies in humans

Journal of Mass Spectrometry

Volumn 35, Issue 6, 2000, Pages 698-704

  Gopaul, S V ^a   Farrell, K ^a   Abbott, F S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Gas chromatography; Liquid chromatography tandem mass spectrometry; Negative ion chemical ionization; Positive electrospray ionization; Valproic acid, N acetylcysteine conjugates

Indexed keywords

ACETYLCYSTEINE; DRUG METABOLITE; VALPROIC ACID;

ACCURACY; ADOLESCENT; ARTICLE; CALIBRATION; CASE REPORT; CHILD; CONTROLLED STUDY; DRUG METABOLISM; DRUG URINE LEVEL; EXTRACTION; GAS CHROMATOGRAPHY; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METHODOLOGY; PRIORITY JOURNAL; STANDARD; TANDEM MASS SPECTROMETRY; URINARY EXCRETION;

ACETYLCYSTEINE; ADOLESCENT; ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, LIQUID; EPILEPSY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; MASS SPECTROMETRY; RATS; VALPROIC ACID;

ANIMALIA;

EID: 0034039312     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-9888(200006)35:6<698::AID-JMS996>3.0.CO;2-S     Document Type: Article

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