Use of a non-rigid region in T4 lysozyme to design an adaptable metal-binding site

Protein Engineering

Volumn 13, Issue 5, 2000, Pages 313-321

  Wray, Jonathan W ^a,c   Baase, Walter A ^c   Ostheimer, Gerard J ^c   Zhang, Xue Jun ^b,c   Matthews, Brian W ^c  

^a Advanced Medicine Inc   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^c UNIVERSITY OF OREGON   (United States)

Author keywords

Divalent metals; Flexibility; Hinge bending; Protein stability

Indexed keywords

COBALT; DIVALENT CATION; GLUTAMINE; HISTIDINE; LYSOZYME; NICKEL; POLYPEPTIDE; THREONINE; ZINC;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIOPHAGE T4; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; GEOMETRY; METAL BINDING; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; SPECTROSCOPY; TEMPERATURE;

EID: 0034038551     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/13.5.313     Document Type: Article

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