Topographically based search for an 'ethogram' among a series of novel D4 dopamine receptor agonists and antagonists

Neuropsychopharmacology

Volumn 22, Issue 5, 2000, Pages 538-544

  Clifford, Jeremiah J ^a   Waddington, John L ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

Behavioral topography; CP 226,269; CP 293,019; D4 agonists; D4 antagonists; D4 dopamine receptor; Ethological assessment; L 745,870; PD 168077; Ro 61 6270

Indexed keywords

3 [[4 (4 CHLOROPHENYL) 1 PIPERAZINYL]METHYL] 1H PYRROLO[2,3 B]PYRIDINE; 7 (4 FLUOROPHENOXYMETHYL) 2 (5 FLUORO 2 PYRIMIDINYL) 2,3,4,6,7,8,9,9A OCTAHYDROPYRIDO[1,2 A]PYRAZINE; CP 226269; DOPAMINE 2 RECEPTOR STIMULATING AGENT; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; HALOPERIDOL; N (3 HYDROXYPHENETHYL) N (PHENETHYL)PROPYLAMINE; PD 168077; RO 616270; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; HABITUATION; LOCOMOTION; MALE; MASTICATION; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOTYPY; TOPOGRAPHY;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BRAIN MAPPING; DOPAMINE AGONISTS; DOPAMINE ANTAGONISTS; HABITUATION, PSYCHOPHYSIOLOGIC; MALE; PSYCHOTIC DISORDERS; PYRAZINES; PYRIDINES; PYRIMIDINES; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4;

EID: 0034019852     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(99)00141-4     Document Type: Article

References (35)

1. 4 receptor antagonist, does not exhibit a neuroleptic-like profile in rodent behavioral tests. J Pharmacol Exp Ther. 283:1997;1256-1263.
2. 3 dopamine receptor antagonists using an ethologically based approach. Psychopharmacology. 136:1998;284-290.
3. 1A dopamine receptor. Paradoxical elevation of grooming syntax Neuropharmacology. 37:1998;1595-1602.
4. Colgan P.W. Quantitative Ethology. 1978;Wiley, New York.
5. 2-like" agonist RU 24213. Psychopharmacology. 124:1996;40-49.
6. 1-like" dopamine receptor agonists. Pharmacol Biochem Behav. 58:1997;551-558.
7. Euvrard C., Ferland L., Di Paulo T., Beaulieu M., Labrie F., Oberlander C., Raynaud J.P., Boissier J.R. Activity of two new potent dopaminergic agonists at the striatal and anterior pituitary levels. Neuropharmacology. 19:1980;379-386.
8. Gerlai R., Clayton N.S. Analyzing hippocampal function in transgenic mice. An ethological perspective Trends Neurosci. 22:1999;47-51.
9. 4 agonists J Med Chem. 40:1997;1771-1772.
10. Goudie A.J., Smith J.A., Taylor A., Taylor M.A.I., Tricklebank M.D. Discriminative stimulus properties of the atypical neuroleptic clozapine in rats. Tests with subtype selective receptor ligands Behav Pharmacol. 9:1998;699-710.
11. 4 receptor antagonist induces c-fos expression in mouse cortex. Soc Neurosci Abstr. 22:1996;498.
12. 4 receptor. Eur J Pharmacol. 314:1996;229-233.
13. 4 selective dopamine antagonist produces clozapine-like effects on c-fos mRNA and dopamine levels in rat brain Soc Neurosci Abstr. 22:1996;1771.
14. Jaber M., Robinson S.W., Missale C., Caron M.G. Dopamine receptors and brain function. Neuropharmacology. 35:1996;1503-1519.
15. 4 receptor antagonist reversal of subchronic phencyclidine-induced object retrieval/detour deficits in monkeys. Psychopharmacology. 142:1999;78-84.
16. 4 dopamine receptor antagonist (L-745,870) in acutely psychotic inpatients with schizophrenia. Arch Gen Psychiat. 54:1997;567-572.
17. 4 receptor antagonists reverse apomorphine-induced blockade of prepulse inhibition. Psychopharmacology. 135:1998;194-200.
18. 4 receptor selective antagonist. J Pharmacol Exp Ther. 279:1996;1392-1403.
19. 4 receptors. An in vitro and in vivo comparison with L 745, 870 (3-(4-[4-chlorophenyl]piperazin-1-yl)methyl-1H-pyrrolo[2,3b]pyridine) and raclopride J Pharmacol Exp Ther. 287:1998;167-186.
20. Missale C., Nash S.R., Robinson S.W., Jaber M., Caron M.G. Dopamine receptors. from structure to function Physiol Rev. 78:1998;189-225.
21. Neve K.A., Neve R.L. The Dopamine Receptors. 1997;Humana Press, Totowa.
22. 4 receptor. J Pharmacol Exp Ther. 283:1997;636-647.
23. 4, receptor subtype is essential for the disruption of prepulse inhibition produced by amphetamine in mice. J Neurosci. 19:1999;4627-4633.
24. 4 receptors are supersensitive to ethanol, cocaine, and methamphetamine. Cell. 90:1997;991-1001.
25. Sams-Dodd F. Effects of dopamine agonists and antagonists on PCP-induced stereotyped behavior and social isolation in the rat social interaction test. Psychopharmacology. 135:1998;182-193.
26. 4 receptor antagonist Bioorg Med Chem Lett. 8:1998;725-730.
27. 4 receptors. Neuropsychopharmacology. 16:1997;93-110.
28. Tallman J.F. Ngd 94-1. A specific dopamine-4-receptor antagonist Goldstein D., Eisenhofer G., McCarthy R. Catecholamines. Bridging Basic Science with Clinical Medicine:1998;490-492 Academic Press, San Diego.
29. 4 receptors. Basic and clinical status Int J Neuropsychopharmacol. 2:1999;41-58.
30. 2A antagonist fananserin in the treatment of schizophrenia. Am J Psychiat. 156:1999;419-425.
31. 4 receptor gene with high affinity for the antipsychotic clozapine. Nature. 350:1991;614-619.
32. 1 antagonist Pharmacol Ther. 43:1989;1-52.
33. Waddington J.L., Daly S.A., Downes R.P., Deveney A.M., McCauley P.G., O'Boyle K.M. Behavioral pharmacology of "D-1-like" dopamine receptors. Further subtyping, new pharmacological probes, and interactions with "D-2-like" receptors Prog Neuro-Psychopharmacol Biol Psychiat. 19:1995;811-831.
34. 1A targeted gene deletion Jenner P., Demirdamar R. Dopamine Receptor Subtypes. 1998;45-63 IOS Press, Amsterdam.
35. 4 receptor agonist. Soc Neurosci Abstr. 23:1997;685.