Stimulatory effects of δ-hexachlorocyclohexane on Ca2+-activated K+ currents in GH3 lactotrophs

Molecular Pharmacology

Volumn 57, Issue 5, 2000, Pages 865-873

  Wu, Sheng Nan ^a   Li, Hui Fang ^a   Chiang, Hung Ting ^a  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; DANTROLENE; HEXACHLOROCYCLOHEXANE; INOSITOL 1,4,5 TRISPHOSPHATE; NEUROTRANSMITTER; PAXILLINE; POTASSIUM ION; RUTHENIUM RED; RYANODINE;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NEUROSECRETORY CELL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

ACTION POTENTIALS; ANIMALS; CALCIUM; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DANTROLENE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC CONDUCTIVITY; ESTRADIOL; HUMANS; INDOLES; INOSITOL 1,4,5-TRISPHOSPHATE; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; LINDANE; NEUROBLASTOMA; PITUITARY GLAND; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RUTHENIUM; RYANODINE; TUMOR CELLS, CULTURED;

EID: 0034015262     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Aspinwall LS, Bermudez I, King LA and Wafford KA (1997) The interactions of hexachlorocyclohexane isomers with human gamma-aminobutyric acid (A) receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther 282:1557-1564.
2. Barron S, Serratosa J and Tusell JM (1995) Regulation of c-fos expression by convulsants and hexachlorocyclohexane isomers in primary cultures of cortical neurons. J Neurochem 64:1708-1714.
3. Belelli D, Callachan H, Hill-Venning C, Peters JA and Lambert JJ (1996) Interaction of positive allosteric modulators with human and Drosophila recombinant GABA receptors expressed Xenopus laevis oocytes. Br J Pharmacol 118:563-576.
4. 1 receptor. Br J Pharmacol 127: 601-604.
5. Bhalla P and Agrawal D (1998) Alterations in rat erythrocyte membrane due to hexachlorocyclohexane (technical) exposure. Hum Exp Toxicol 17:638-642.
6. Bloomquist JR (1992) Intrinsic lethality of chloride-channel-directed insecticides and convulsants in mammals. Toxicol Lett 60:289-298.
7. +-selective ionophore activity. J Pharmacol Exp Ther 289:486-493.
8. Carl A and Sanders KM (1990) Measurement of single channel open probability with voltage ramps. J Neurosci Methods 33:157-163.
9. Cristofol RM and Rodriguez-Farre E (1993) Modulation of noradrenaline release from hippocampal slices by hexachlorocyclohexane isomers: Effects of GABAergic compounds. Brain Res 606:237-243.
10. Cristofol RM and Rodriguez-Farre E (1994) Hippocampal noradrenaline release is modulated by gamma-and delta-hexachlorocyclohexane isomers: Which mechanisms are involved? Eur J Pharmacol 252:305-312.
11. Doong RA, Lee CY and Sun YC (1999) Dietary intake and residues of organochlorine pesticides in foods from Hsinchu, Taiwan. J AOAC Int 82:677-682.
12. Hamill OP, Marty A, Neher E, Sakmann B and Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391:85-100.
13. Kaczorowski GJ, Knaus H-G, Leonard RJ, McManus OB and Garcia ML (1996) High conductance calcium-activated potassium channels: Structure, pharmacology, and function. J Bioenerg Biomembr 28:255-267.
14. McManus OB, Blatz AL and Magleby KL (1987) Sampling, log binning, fitting, and plotting durations of open and shut intervals from single channels and the effects of noise. Pflügers Arch 410:530-553.
15. 2+ entry in rat basophilic leukemia cells. Mol Pharmacol 48:512-522.
16. Nagata K, Huang CS, Hamilton BJ, Carter DB and Narahashi T (1996) Differential effects of hexachlorocyclohexane isomers on the GABA receptor subunits expressed in human embryonic kidney cell line. Brain Res 738:131-137.
17. Nagata K and Narahashi T (1995) Differential effects of hexachlorocyclohexane isomers on the GABA receptor-chloride channel complex in rat dorsal root ganglion neurons. Brain Res 704:85-91.
18. Narahashi T (1996) Neuronal ion channels as the target sites of insecticides. Pharmacol Toxicol 79:1-14.
19. Narahashi T, Ginsburg KS, Nagata K, Song JH and Tatebayashi H (1998) Ion channels as targets for insecticides. Neurotoxicology 19:581-590.
20. Pessah IN, Mohr FC, Schiedt M and Joy RM (1992) Stereoselective modulation of ryanodine-sensitive calcium channels by the delta isomer of hexachlorocyclohexane (delta-HCH). J Pharmacol Exp Ther 262:661-669.
21. Pomes A, Rodriguez-Farre E and Sunol C (1994) Disruption of GABA-dependent chloride flux by cyclodienes and hexachlorocyclohexanes in primary cultures of cortical neurons. J Pharmacol Exp Ther 271:1616-1623.
22. Robitaille R and Charlton MP (1992) Presynaptic calcium signals and transmitter release are modulated by calcium-activated potassium channels. J Neurosci 12: 297-305.
23. Rosa R, Sanfeliu C, Rodriguez-Farre E, Prandsen A, Schousboe A and Sunol C (1997a) Properties of ryanodin receptors in cultured cerebellar granule neurons: Effects of hexachlorocyclohexane isomers and calcium. J Neurosci Res 47:27-33.
24. 2+ homeostasis in cultured cerebellar granule neurons is different for the gamma-and delta-isomers. Toxicol Appl Pharmacol 142:31-39.
25. + channels. Biochem Biophys Res Commun 214:367-372.
26. Sanchez M and McManus OB (1996) Paxilline inhibition of the alpha-subunit of the high-conductance calcium-activated potassium channel. Neuropharmacology 35: 963-968.
27. 2+ influx. Biochem J 321:691-698.
28. Srivastava SC, Kumar R, Prasad AK and Srivastava SP (1995) Effect of hexachlorocyclohexane (HCH) on testicular plasma membrane of rat. Toxicol Lett 75:153-157.
29. Steinmetz R, Young PC, Caperell-Grand A, Gize EA, Madhukar BV, Ben-Jonathan N and Bigsby RM (1996) Novel estrogenic action of the pesticide residue beta-hexachlorocyclohexane in human breast cancer cells. Cancer Res 56:5403-5409.
30. Sun X-P, Schlichter LC and Stanley EF (1999) Single channel properties of BK-type calcium-activated potassium channels at a cholinergic presynaptic nerve terminal. J Physiol 518:639-651.
31. Tusell JM, Barron S and Serratosa J (1994) Anticonvulsant activity of calmodulin antagonist W-7 in convulsions induced by lindane and Bay K-8644: Effects in c-fos expression. Neurotoxicology 15:751-756.
32. Vendrell M, Tusell JM and Serratosa J (1992) c-fos expression as a model for studying the action of hexachlorocyclohexane isomers in the CNS. J Neurochem 58:862-869.
33. Verma SP and Singhal A (1991) Low levels of the pesticide, delta-hexachlorocyclohexane, lyses human erythrocytes and alters the organization of membrane lipids and proteins as revealed by Raman spectroscopy. Biochem Biophys Acta 1070:265-273.
34. 3 cells. J Pharmacol Exp Ther 290:998-1005.
35. 2+ current. Brain Res 812:133-141.
36. 3 cells. Neuropharmacology 38:979-989.