Pharmacological characterization of leukotriene receptors

American Journal of Respiratory and Critical Care Medicine

Volumn 161, Issue 2 II, 2000, Pages

  Dahlén, Sven Erik ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 METHOXY 4 [(PHENYLSULFONYLAMINO)CARBONYL]BENZYL] 1H INDAZOLE 6 CARBAMIC ACID CYCLOPENTYL ESTER; 2 [2 PROPYL 3 [3 [2 ETHYL 4 (4 FLUOROPHENYL) 5 HYDROXYPHENOXY]PROPOXY]PHENOXY]BENZOIC ACID; 2 [4 [2 (5 TETRAZOLYLMETHYL)BENZYLOXY]PHENOXYMETHYL]QUINOLINE; 3 [(2 CARBOXYETHYL)THIO] 3 [2 (8 PHENYLOCTYL)PHENYL]PROPIONIC ACID; 4 (4 CARBOXYPHENYLTHIO) 7 [4 (4 PHENOXYBUTOXY)PHENYL] 5 HEPTENOIC ACID; 6 (4 CARBOXYPHENYLTHIO) 5 HYDROXY 7,9,11,14 ICOSATETRAENOIC ACID; 7 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY) 2 HYDROXYPROPOXY] 4 OXO 8 PROPYL 4H 1 BENZOPYRAN 2 CARBOXYLIC ACID; CGP 45715; IRALUKAST; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE E4; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; MONTELUKAST; POBILUKAST; PRANLUKAST; TOMELUKAST; UNCLASSIFIED DRUG; VERLUKAST; ZAFIRLUKAST;

BLOOD VESSEL REACTIVITY; BRONCHOSPASM; CHEMOKINESIS; CHEMOTAXIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; RECEPTOR BINDING; RECEPTOR BLOCKING; REVIEW;

EID: 0034011524     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.161.supplement_1.ltta-9     Document Type: Review

References (80)

1. Coleman, R. A., R. M. Eglen, R. L. Jones, S. Narumiya, T. Shimizu, W. L. Smith, S.-E Dahlén, J. M. Drazen, P. J. Gardiner, W. T. Jackson, T. R. Jones, R. D. Krell, and S. Nicosia. 1994. Prostanoid and leukotriene receptors: a progress report from the IUPHAR Working Parties on Classification and Nomenclature. Adv. Prostaglandin Thromboxane Leukotriene Res. 23:283-285.
2. 4 to a receptor on human polymorphonuclear leukocytes. J. Exp. Med. 157:628-632.
3. 4 binding to human neutrophils. Prostaglandins 28:837-845.
4. Goldman, D. W., F. H. Chang, L. A. Gifford, E. J. Goetzl, and H. R. Bourne. 1985. Pertussis toxin inhibition of chemotactic factor induced calcium mobilization and function in hman polymorphonuclear leukocytes. J. Exp. Med. 162:145-156.
5. 4 receptor in sheep lung membranes. J. Pharm. Exp. Ther. 265:841-847.
6. 4 from leukocyte membrane preparations by (12R)-and (12S)-hydroxyeicosatetraenoic acid. Biochim. Biophys. Acta 917:406-410.
7. 4, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature (London) 286:264-265.
8. Dahlén, S.-E., J. Björk, P. Hedqvist, K.-E. Arfors, S. Hammarström, J. Å. Lindgren, and B. Samuelsson. 1981. Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc. Natl. Acad. Sci U.S.A. 78:3887-3891.
9. 4: an inflammatory mediator in vivo. Prostaglandins 22:213-222.
10. Sehmi, R., A. J. Wardlaw, O. Cromwell, K. Kurihawa, P. Waltman, and A. B. Kay. 1992. Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood 79:2952-2959.
11. 4 induces interleukin-5 generation from human T lymphocytes. Eur. J. Immunol. 23:2392-2398.
12. 4 - a stereospecific stimulator for release of lysosomal enzymes from neutrophils. FEBS Lett. 130:14-17.
13. 4. Pharm. Pharmacol. 33:616-618.
14. 4. Biochem. Biophys. Res. Commun. 153:203-208.
15. 4 enhances IL-4-induced IgE production from normal human lymphocytes. Cell. Immunol. 156: 124-134.
16. 4 pathway to inflammation control. Nature (London) 384:39-43.
17. Serhan, C. N. 1996. Signalling the fat controller. Nature (London) 384:23-24.
18. Lewis, R. A., E. J. Goetzl, J. M. Drazen, N. A. Soter, K. F. Austen, and E. J. Corey. 1981. Functional characterization of synthetic leukotriene B and its stereochemical isomers. J. Exp. Med. 154:1243-1248.
19. 4 in guinea-pig lung in vitro. Br. J. Pharmacol. 77:267-275.
20. 4) on the guinea-pig lung. Prostaglandins Leukotrienes Med. 8:157-170.
21. 4 acts indirectly. Acta Physiol. Scand. 118:393-403.
22. 4 induces airway hyperresponsiveness in dogs. J. Appl. Physiol. 59:1941-1946.
23. 2 on bronchial responsiveness to histamine in normal subjects. Thorax 44:491-495.
24. 4 in the human lung. J. Clin. Invest. 94:1609-1619.
25. 4 in normal and asthmatic subjects. Am. J. Respir. Crit. Care Med. 155:1789-1792.
26. 4 that mediates chemotaxis. Nature (London) 387:620-624.
27. Owman, C., C. Nilsson, and S. J. Lolait. 1996. Cloning of cDNA encoding a putative chemoattractant receptor. Genomics 37:187-194.
28. 4 and used by human immunodeficiency virus type 1 to infect CD4-positive immune cells: a therapeutic connection to asthma? Am. J. Respir. Crit. Care Med. 161(Suppl. 1):S56-S61.
29. 4 and its L-oxidized metabolites. FEBS Lett. 136:141-148.
30. 4 to guinea pig lung membranes. Biochem. Biophys. Res. Commun. 143:364-371.
31. 4. Tetrahedron Lett. 29:143-146.
32. 4 receptor antagonist, LY293111, on allergen-induced responses in asthma. Thorax 51:1178-1184.
33. Drazen, J. M., K. F. Austen, R. A. Lewis, D. A. Clark, G. Goto, and E. J. Corey. 1980. Comparative airway and vascular activities of leukotrienes C-1 and D in vivo and in vitro. Proc. Natl. Acad. Sci. U.S.A. 77: 4354-4358.
34. 4. Acta Physiol. Scand. 110:331-333.
35. Dahlén, S.-E., P. Hedqvist, S. Hammarström, and B. Samuelsson. 1980. Leukotrienes are potent constrictors of human bronchi. Nature (London) 288:484-486.
36. Hanna, C. J., M. K. Bach, P. D. Pare, and R. R. Schellenberg. 1981. Slow reacting substances (leukotrienes) contract human airway and pulmonary vascular smooth muscle. Nature (London) 290:343-344.
37. 4 on isolated human airway smooth muscle. Can. J. Physiol. Pharmacol. 60:638-643.
38. 4 cause extensive and widespread plasma extravasation in the guinea pig. Naunyn-Schmiedeberg's Arch. Pharmacol. 330:136-141.
39. Gardiner, P. J., T. S. Abram, and N. J. Cuthbert. 1990. Evidence for two leukotriene receptor types in the guinea-pig isolated ileum. Eur. J. Pharmacol. 182:291-299.
40. Weichman, B. M., R. M. Muccitelli, R. R. Osborn, D. A. Holden, J. G. Gleason, and M. A. Wasserman. 1982. In vitro and in vivo mechanisms of leukotriene-mediated bronchoconstriction in the guinea pig. J. Pharm. Exp. Ther. 222:202-208.
41. 4-induced airway hyperresponsiveness of guinea pig tracheal smooth muscle to histamine and evidence for three separate sulfidopeptide receptors. Proc. Natl. Acad. Sci. U.S.A. 81:4922-4925.
42. 4-induced histamine hyperresponsiveness in guinea-pig tracheal and human bronchial smooth muscle in vitro. Br. J. Pharmacol. 104:859-866.
43. Buckner, C. K., J. S. Fedyna, J. L. Robertson, J. A. Will, D. M. England, R. D. Krell, and R. Saban. 1990. Examination of the influence of the epithelium on contractile responses to peptidoleukotrienes and blockade by ICI 204,219 in isolated guinea-pig trachea and human intralobar airways. J. Pharm. Exp. Ther. 252:77-85.
44. 4. J. Pharm. Exp. Ther. 237:558-562.
45. 4 on glycoprotein and Iysozyme secretion by human bronchial mucosa. Prostaglandins 25:155-170.
46. 0, increase the release of mucus from human airways in vitro. Am. Rev. Respir. Dis. 126:449-451.
47. 4 on mucin release into the cat trachea in vivo and in vitro. Br. J. Pharmacol. 77:391-393.
48. 2 release by leukotrienes in isolated guinea pig hearts. Eur. J. Pharmacol. 73:357-361.
49. 4 on guinea-pig isolated hearts. Br. J. Pharmacol. 76:169-176.
50. 4: a potent coronary artery vasoconstrictor associated with impaired ventricular contraction. Science 217:841-843.
51. 4: effects on human and guinea-pig cardiac preparations in vitro. J. Pharm. Exp. Ther. 221:235-241.
52. 4 causes granulocyte infiltration into asthmatic airways. Lancet 341:989-990.
53. 4 and methacholine on sputum cell differentials in asthma. Am. J. Respir. Crit. Care Med. 155:1247-1253.
54. 4 receptor antagonist pranlukast or an interleukin-5 monoclonal antibody. Am. J. Respir. Crit. Care Med. 154:850-857.
55. Munoz, N. M., I. Douglas, I. Mayer, A. Herrnreiter, X. Zhu, and A. R. Leff. 1997. Eosinophil chemotaxis inhibited by 5-lipoxygenase blockade and leukotriene receptor antagonism. Am. J. Respir. Crit. Care Med. 155:1398-1403.
56. Peppelenbosch, M. P., L. G. J. Teretoolen, W. J. Hage, and S. W. de Laat. 1993. Epidermal growth factor-induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products. Cell 74:565-575.
57. 4 in allergen-induced increased in airway smooth muscle in the rat. Am. Rev. Respir. Dis. 148:413-417.
58. Augstein, J., J. B. Farmer, T. B. Lee, P. Sheard, and M. L. Tattersall. 1973. Selective inhibitor of slow reacting substance of anaphylaxis. Nature New Biol. 245:215-217.
59. 4 receptors in smooth muscle. Life Sci. 31:577-581.
60. Krell, R. D., B. S. Tsai, A. Berdoulay, M. Barone, and R. E. Giles. 1983. Heterogeneity of leukotriene receptors in the guinea-pig trachea. Prostaglandins 25:171-178.
61. 4 receptor in guinea-pig trachea. J. Pharm. Exp. Ther. 231:616-622.
62. 4-induced contractions of guinea-pig trachea. Br. J. Pharmacol. 91:179-188.
63. Morris, H. R., G. W. Taylor, C. M. Jones, P. J. Piper, M. N. Samhoun, and J. R. Tippins. 1982. Slow-reacting substances (leukotrienes): enzymes involved in their biosynthesis. Proc: Natl. Acad. Sci. U.S.A. 79: 4838-4842.
64. 4, and antigen in vitro. Am. Rev. Respir. Dis. 146:923-929.
65. Labat, C., J. L. Ortiz, X. Norel, I. Gorenne, J. Verkey, T. S. Abram, N. J. Cuthbert, S. R. Tudhope, P. Normann, P. J. Gardiner, and C. Brink. 1992. A second cysteinyl leukotriene receptor in human lung. J. Pharm. Exp. Ther. 263:800-805.
66. Snyder, D. W., and R. D. Krell. 1986. Pharmacology of peptide leukotrienes on ferret isolated airway smooth muscle. Prostaglandins 32:189-200.
67. 4 in the guinea-pig ileum. Eur. J. Pharmacol. 317:107-113.
68. Tudhope, S. R., N. J. Cuthbert, T. S. Abram, M. A. Jennings, R. J. Maxey, A. M. Thompson, P. Norman, and P. J. Gardiner. 1994. BAY u9773, a novel antagonist of cysteinyl-leukotrienes with activity against two receptor subtypes. Eur. J. Pharmacol. 264:317-323.
69. Wikström-Jonsson, E. 1997. Functional characterisation of receptors for cysteinyl-leukotrienes in sheep trachealis muscle. Pulm. Pharm. Ther. 10:29-36.
70. Ortiz, J. L., I. Gorenne, J. Cortijo, A. Seller, C. Labat, B. Sarria, T. S. Abram, P. J. Gardiner, E. Morcillo, and C. Brink. 1995. Leukotriene receptors on human pulmonary vascular endothelium. Br. J. Pharmacol. 115:1382-1386.
71. Wikström Jonsson, E., U. Rosenqvist, and S.-E. Dahlén. 1998. Agonist and antagonist activities of the leukotriene analogue BAY u9773 in the guinea-pig lung. Eur. J. Pharmacol. 357:203-211.
72. 4 to membranes from guinea-pig lung: regulation by ions and guanine nucleotides. Life Sci. 33:645-653.
73. 4 receptor in guinea pig lung. Proc. Natl. Acad. Sci. U.S.A. 80:7415-7420.
74. Lewis, M. A., S. Mong, R. L. Veseela, and S. T. Crooke. 1985. Characterization of leukotriene D4 receptors in adult and fetal human lung. Biochem. Pharmacol. 34:4311-4317.
75. 4 in membranes from guinea pig ileal longitudinal muscle. Prostaglandins 27:483-494.
76. 4 in membranes from human lung. Biochem. Pharmacol. 34:2831-2837.
77. 4 in human bronchi. J. Pharmacol. Exp. Ther. 242:189-198.
78. 4-binding protein in rat liver cytosol as glutathione S-transferase. J. Biol. Chem. 261:8540-8546.
79. 4 is a tight-binding inhibitor of microsomal glutathione transferase-1. J. Biol. Chem. 274:1994-1999.
80. 4 synthase. J. Biol. Chem. 271:22203-22210.