Apoptosis and apoptosis-related proteins (Fas, Fas ligand, bcl-2, p53) in macrophages of human ovarian epithelial tumors

European Journal of Gynaecological Oncology

Volumn 21, Issue 2, 2000, Pages 141-145

  Ben Hur, H ^a   Gurevich, P ^a   Ben Arie, A ^a   Huszar, M ^a   Berman, V ^a   Tendler, Y ^b   Tchanishev, R ^a   Mor, G ^c   Gershon, S ^d   Zusman, I ^d  

^a KAPLAN MEDICAL CENTER   (Israel)

^b RAMBAM MEDICAL CENTER   (Israel)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Apoptosis; Bcl 2; Fas; Fas ligand; Macrophages; Ovarian tumors

Indexed keywords

FAS LIGAND; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CLINICAL ARTICLE; EPITHELIUM TUMOR; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTIC INFILTRATION; MACROPHAGE; OVARY CARCINOMA; OVARY CYST; OVARY TUMOR; PARENCHYMA; STROMA;

AGED; ANTIGENS, CD59; APOPTOSIS; CARCINOMA; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MIDDLE AGED; MULTIVARIATE ANALYSIS; OVARIAN NEOPLASMS; PROBABILITY; PROTO-ONCOGENE PROTEINS C-BCL-2; REGRESSION ANALYSIS; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034010902     PISSN: 03922936     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Valkovic T., Lucin K., Krstulja M., Dobi-Babic R., Jonjic N.: "Expression of monocyle chemotactic protein-1 in human invasive ductal breast cancer". Path. Res. Pract., 1998, 194, 335.
2. Jonjic N., Valkovic T., Lucin K., Iternicka Z., Krstulja M., Mustac E., Dobi-Babic R. et al.: "Comparison of microvessel density with tumor associated macrophages in invasive breast carcinoma". Anticancer Res., 1998, 18, 3767.
3. Mor G., Yue W., Santen R. J., Gutierrez L., Eliza M., Bernstein L., Harada N. et al.: "Macrophages, estrogen and the microenvironment of breast cancer". J. Steroid. Biochem. Mol. Biol., 1998, 67, 403.
4. Leber T. M., Balkwill F. R.: "Regulation of monocyte MMP-9 production by TNF-alpha and a tumour-derived soluble factor (MMPSF)". Br. J. Cancer, 1998, 78, 724.
5. Mor G., Gutierrez L. S., Eliza M., Kahyaogili F., Arici A.: "Induction of apoptosis mediated by the Fas-Fas ligand system in human placental trophoblast and gestational trophoblastic disease". Am. J. Reprod. Immunol., 1998, 40, 89.
6. Gutierrez L., Eliza M., Niven-Fairchild T., Mor G.: "Fas/Fas-ligand system induced apoptosis in human breast carcinoma: a mechanism for immune evasion". Breast Cancer Res. Treatment, 1999, 54, 245.
7. Liu D. L., Yang M. Q., Eberhardt J., Persson B.: "Repeated immunotherapy using intratumoral injection with recombinant interleukin-2 and tumor-infiltrating lymphocytes". Cancer Lett., 1996, 103, 131.
8. Ridolfi R., Flamini E., Ricobon A., DePaola F., Maltoni R., Gardini A., Ridolfi L. et al.: "Adjuvant adaptive immunotherapy with tumour-infiltrating lymphocytes and modulated doses of interleukin-2 in 22 patients with melanoma, colorectal and renal cancer, after radical metastasectomy, and in 12 advanced patients". Cancer Immunol. Immunother., 1998, 46, 185.
9. Zhang X. D., Schiller G. D., Gill P. G., Conventry B. J.: "Lymphoid cell infiltration during breast cancer growth: a syngeneic rat model", Immunol. Cell. biol., 1998, 76, 550.
10. Ben-Hur H., Gurevich P., Huszar M., Berman V., Tendler Y., Ben-Arie A., Zinder O. et al.: "Apoptosis and apoptotic-related proteins (Fas, Fas ligand, bcl-2, p53) in lymphoid elements of human ovarian epithelial tumors". Eur. J. Gynaec. Oncol., 1999a, 21.
11. Spielman J., Lee R. K., Podack E. R.: "Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitis". J. Immunol., 1998, 161, 7063.
12. Elgert K. D., Alleva D. G., Mullins D. W.: "Tumor-induced immune dysfunction: the macrophage connection". J. Leukocite Biol., 1998, 64, 275.
13. Orre M., Rogers P. A. W.: "Macrophages and microvessel density in tumors of the ovary". Gynecol. Oncol., 1999, 73, 47.
14. Senturk L. M., Seli E., Gutierrez L. M., Mor G., Zeyneloglu H. B., Arici A.: "Monocyte chemoattractant protein-1 expression in human corpus luteum". Mol. Hum. Reprod., 1999, 5, 697.
15. Harmey J. H., Dimitriadis E., Kay E., Redmond H. P., Bouchier-Hayes D.: "Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1". Ann. Surg. Oncol., 1998, 5, 271.
16. Negus R. P., Stamp G. W., Hadley J., Balkwill F. R.: "Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines". Am. J. Path., 1997, 150, 1723.
17. Merogi A. J., Marrogi A. J., Ramesh R., Robinson W. R., Fermin C. D., Freeman S. M.: "Tumor-host interaction: analysis of cytokines, growth factors, and tumor-infiltrating lymphocytes in ovarian carcinomas". Hum. Path., 1997, 28, 321.
18. Garcia-Velasces J., Arici A., Naftolin F., Zreick T., Mor G.: "Macrophage-derived growth factors regulate Fas Ligand expression in endometrial stromal cells. A role in endometriosis". Mol. Hum. Reprod., 1999, 5, 642.
19. Ben-Hur H., Gurevich P., Huszar M., Berman V., Ben-Arie A., Tendler Y., Zinder O. et al.: "Expression of apoptosis and apoptosis-related proteins in epithelial cells of human ovarian tumors: immunohistochemical and morphometric studies". Eur. J. Gynaec. Oncol., 1999b, 20, 249.