Succinylpurinemic autism: Increased sensitivity of defective adenylosuccinate lyase towards 4-hydroxy-2-nonenal

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1500, Issue 3, 2000, Pages 335-341

  Salerno, Costantino ^a   Siems, Werner G ^b   Crifò, Carlo ^b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Herzog Julius Klinik GmbH & Co KG   (Germany)

Author keywords

4 Hydroxy 2 nonenal; Adenylosuccinate lyase; Inherited diseases; Lipid peroxidation; Psychomotor retardation

Indexed keywords

4 HYDROXYNONENAL; ADENYLOSUCCINATE LYASE; DITHIOTHREITOL; ENZYME INHIBITOR; HYDROXYLAMINE; ISOENZYME; PURINE DERIVATIVE; SUCCINYLPURINE; UNCLASSIFIED DRUG;

ARTICLE; AUTISM; CONCENTRATION RESPONSE; ENZYME INHIBITION; INHIBITION KINETICS; METABOLIC DISORDER; MISSENSE MUTATION; PRIORITY JOURNAL; PURINE METABOLISM;

ADENYLOSUCCINATE LYASE; ALDEHYDES; AUTISTIC DISORDER; CYSTEINE PROTEINASE INHIBITORS; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYDROXYLAMINE; KINETICS; PURINES;

EID: 0034007601     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(99)00117-9     Document Type: Article

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