The alpha-fetoprotein promoter is the target of Afr1-mediated postnatal repression

Genomics

Volumn 63, Issue 2, 2000, Pages 173-180

  Peyton, David K ^a   Huang, Mei Chuan ^a   Giglia, Meredith A ^a   Hughes, Nedda K ^a   Spear, Brett T ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN;

ANIMAL TISSUE; ARTICLE; ENHANCER REGION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE REPRESSION; HUMAN; HUMAN CELL; LIVER CARCINOMA; LIVER REGENERATION; MOUSE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION;

ANIMALIA;

EID: 0034007475     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1999.6073     Document Type: Article

References (37)

1. Abelev G. I. Alpha-fetoprotein in oncogenesis and its association with malignant tumors. Adv. Cancer Res. 14:1971;295-358.
2. Apergis G. A., Crawford N., Ghosh D., Steppan C. M., Vorachek W. R., Wen P., Locker J. A novel nk-2-related transcription factor associated with human fetal liver and hepatocellular carcinoma. J. Biol. Chem. 273:1998;2917-2925.
3. Auffray C., Rougeon F. Purification of mouse immunoglobulin heavy-chain mRNAs from total myeloma tumor RNA. Eur. J. Biochem. 107:1980;303-314.
4. Belayew A., Tilghman S. M. Genetic analysis of α-fetoprotein synthesis in mice. Mol. Cell. Biol. 2:1982;1427-1435.
5. Blankenhorn E. P., Duncan R., Huppi C., Potter M. Chromosomal location of the regulator of mouse α-fetoprotein, afr-1. Genetics. 119:1988;687-691.
6. Bois-Joyeux B., Danan J.-L. Members of the CAAT/enhancer-binding protein, hepatocyte nuclear factor-1 and nuclear factor-1 families can differentially modulate the activities of the rat α-fetoprotein promoter and enhancer. Biochem. J. 301:1994;49-55.
7. Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10:1996;267-282.
8. Chaudhry A. Z., Lyons G. E., Gronostajski R. M. Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. Dev. Dyn. 208:1997;313-325.
9. Chaudhry A. Z., Vitullo A. D., Gronostajski R. M. Nuclear factor I-mediated repression of the mouse mammary tumor virus promoter is abrogated by the coactivators p300/CBP and SRC-1. J. Biol. Chem. 274:1999;7072-7081.
10. Chen H., Egan J. O., Chiu J.-F. Regulation and activities of α-fetoprotein. Crit. Rev. Eukaryotic Gene Expression. 7:1997;11-41.
11. Cooke D. W., Lane M. D. The transcription factor nuclear factor I mediates repression of the GLUT4 promoter by insulin. J. Biol. Chem. 274:1999;12917-12924.
12. Crawford D. R., Leahy P., Hu C. Y., Chaudhry A., Gronostajski R., Grossman G., Woods J., Hakimi P., Roesler W. J., Hanson R. W. Nuclear factor I regulates expression of the gene for phosphoenolpyruvate carboxykinase (GTP). J. Biol. Chem. 273:1998;13387-13390.
13. Dietrich W., Miller J. C., Steen R. G., Merchant M., Damron N. R., Gross A., Joyce D. C., Wessel M., Dredge R. D., Marquis A., Stein L. D., Goodman N., Page D. C., Lander E. C. A genetic map of the mouse with 4006 simple sequence length polymorphisms. Nat. Genet. 7:1994;220-245.
14. Feuerman M. H., Godbout R., Ingram R. S., Tilghman S. M. Tissue-specific transcription of the mouse α-fetoprotein gene promoter is dependent on HNF-1. Mol. Cell. Biol. 9:1989;4204-4212.
15. Galarneau L., Pare J.-F., Allard D., Hanek D., Levesque L., Tugwood J. D., Green S., Belanger L. The α-fetoprotein locus is activated by a nuclear receptor of the Drosophila FTZ-F1 family. Mol. Cell. Biol. 16:1996;3853-3865.
16. Godbout R., Ingram R. S., Tilghman S. M. Multiple regulatory elements in the intergenic region between the α-fetoprotein and albumin genes. Mol. Cell. Biol. 6:1986;477-487.
17. Godbout R., Ingram R. S., Tilghman S. M. Fine-structure mapping of the three mouse α-fetoprotein enhancers. Mol. Cell. Biol. 8:1988;1169-1178.
18. Godbout R., Tilghman S. M. Configuration of the α-fetoprotein regulatory domain during development. Genes Dev. 2:1988;949-956.
19. Graham F. L., Van der Eb A. J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:1973;456-467.
20. Hammer R. E., Krumlauf R., Camper S. A., Brinster R. L., Tilghman S. M. Diversity of α-fetoprotein gene expression in mice is generated by a combination of separate enhancer elements. Science. 235:1987;53-58.
21. Hayashi Y., Wang W., Ninomiya T., Nagano H., Ohta K., Itoh H. Liver enriched transcription factors and differentiation of hepatoceullular carcinoma. J. Clin. Pathol. Mol. Pathol. 52:1999;19-24.
22. Hogan B., Constantini F., Lacy E. Manipulating the Mouse Embryo. 1986;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
23. McVey J. H., Michaelides K., Hansen L. P., Ferguson-Smith M., Tilghman S., Krumlauf R., Tuddenham E. G. D. A G to A substitution in an HNF-1 binding site in the human α-fetoprotein gene is associated with hereditary persistence of α-fetoprotein (HPAFP). Hum. Mol. Genet. 2:1993;379-384.
24. Olsson M., Lindahl G., Roushlahti E. Genetic control of alpha-fetoprotein synthesis in the mouse. J. Exp. Med. 145:1977;819-830.
25. Pachnis V., Belayew A., Tilghman S. M. Locus unlinked to α-fetoprotein under the control of the murine raf and Rif genes. Proc. Natl. Acad. Sci. USA. 81:1984;5523-5527.
26. Ramesh T., Ellis A. W., Spear B. T. Individual mouse α-fetoprotein enhancer elements exhibit different patterns of tissue-specific and hepatic position-dependent activity. Mol. Cell. Biol. 15:1995;4947-4955.
27. Song Y.-H., Ray K., Liebhaber S. A., Cooke N. A. Vitamin D-binding protein gene transcription is regulated by the relative abundance of hepatocyte nuclear factors 1α and 1β J. Biol. Chem. 273:1998;28408-28418.
28. Spear B. T. Mouse α-fetoprotein gene 5′ regulatory elements are required for postnatal regulation by raf and Rif. Mol. Cell. Biol. 14:1994;6497-6505.
29. Spear B. T. Alpha-fetoprotein gene regulation: Lessons from transgenic mice. Semin. Cancer Biol. 9:1999;109-116.
30. Spear B. T., Tilghman S. M. Role of α-fetoprotein regulatory elements in transcriptional activition in transient heterokaryons. Mol. Cell. Biol. 10:1990;5047-5054.
31. Thomassin H., Hamel D., Bernier D., Guertin M., Belanger L. Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the α-fetoprotein gene. Further analysis of C/EBPb and C/EBPg. Nucleic Acids Res. 20:1992;3091-3098.
32. Tilghman S. M. The structure and regulation of the mouse α-fetoprotein and albumin genes. Oxford Surv. Eukaryotic Genes. 2:1985;160-206.
33. Tilghman S. M., Belayew A. Transcriptional control of the murine albumin: α-fetoprotein locus during development. Proc. Natl. Acad. Sci. USA. 79:1982;5254-5257.
34. Vacher J., Camper S. A., Krumlauf R., Compton R. S., Tilghman S. M. raf regulates the postnatal repression of the mouse α-fetoprotein gene at the posttranscriptional level. Mol. Cell. Biol. 12:1992;856-864.
35. Vacher J., Tilghman S. M. Dominant negative regulation of the mouse α-fetoprotein gene in adult liver. Science. 250:1990;1732-1735.
36. Yoo-Warren H., Pachnis V., Ingram R. S., Tilghman S. M. Two regulatory domains flank the mouse H19 gene. Mol. Cell. Biol. 8:1988;4707-4715.
37. Zhang D.-E., Ge X., Rabek J. P., Papaconstantinou J. Functional analysis of the trans-acting factor binding sites of the mouse α-fetoprotein proximal promoter by site-directed mutagenesis. J. Biol. Chem. 266:1991;21179-21185.